Clinical trials · Washington, D.C., DC
Epilepsy clinical trials in Washington, D.C.
We’re tracking 21 recruiting epilepsy studies with a site in or near Washington, D.C. — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Washington, D.C.
- NCT05135091RecruitingPhase 3
Cell therapy trial for hard-to-control one-sided temporal lobe epilepsy
This Phase 3 study tests a neural cell therapy (NRTX-1001) for adults whose seizures come from one side of the hippocampus and have not improved with standard seizure medicines. The goal is to reduce seizure frequency and improve seizure control where other treatments have not worked.
Washington D.C., District of ColumbiaAges 18–75 - NCT06443463Enrolling by invitationPhase 2
Long-term safety of BHV-7000 in epilepsy
This study checks the long-term safety of BHV-7000 for people who already completed an earlier trial with this drug. You keep taking the same medicine while doctors watch for any side effects over time.
Silver Spring, MarylandAges 18–75 - NCT06132893RecruitingPhase 2/Phase 3
Testing BHV-7000 for hard-to-control focal seizures in adults
This study tests a new medicine called BHV-7000 for adults whose focal seizures (starting in one part of the brain) are not controlled by current treatments. The goal is to see if it can reduce seizures safely.
Silver Spring, MarylandAges 18–75 - NCT06063850RecruitingPhase 1/Phase 2
Gene therapy for adults with hard-to-control epilepsy
This trial tests a one-time gene therapy (AMT-260) for adults whose seizures start in one area of the brain (the temporal lobe) and aren't controlled by medication. The goal is to see if it's safe and reduces seizure frequency.
Bethesda, MarylandAges 18–75 - NCT02531880RecruitingPhase 1
MRI test of a brain barrier issue in hard-to-treat epilepsy
This early-phase study uses a special MRI approach to look for signs that the “blood-brain barrier” is breaking down in people with drug-resistant epilepsy. It may help researchers understand what is happening in the brain and guide future treatments, though it is primarily a testing/study study.
Bethesda, MarylandAges 18–60 - NCT07563881RecruitingPhase 3
Testing RAP-219 for Focal Seizure Control in Adults
This study tests whether a new medication called RAP-219 can help adults with focal seizures (seizures that start in one area of the brain) control their seizures better. You would take this medication alongside your current seizure drugs for about 12 weeks.
Bethesda, MarylandAges 18–75 - NCT05718817Enrolling by invitationPhase 3
Long-term study of XEN1101 for people with epilepsy
This study gives XEN1101 in an open-label way (everyone knows they’re getting the drug) to people who finished earlier epilepsy studies. It aims to see how the treatment continues to work and whether it’s safe over the long term.
Bethesda, MarylandAges 12 years+ - NCT01273129Recruiting
Surgery for epilepsy that medicines cannot control
This trial looks at using brain surgery to treat epilepsy that does not improve with usual medicines, or epilepsy caused by a brain tumor. It may help some people reduce seizures if surgery is appropriate for their situation.
Bethesda, MarylandAges 8–99 - NCT06019182Recruiting
MEHMO syndrome: Understanding the condition over time
This study follows people with or at risk for MEHMO syndrome over time to better understand the condition and identify biological markers. It may include both affected individuals and their family members to see how the condition runs in families.
Bethesda, MarylandAges 1 week–100 years - NCT04095026Enrolling by invitation
Brain recording and stimulation to improve memory
This study tests a brain-recording and brain-stimulation approach to help improve memory. It is offered to adults who are already enrolled in a specific epilepsy surgery program and can safely complete memory-related tasks.
Bethesda, MarylandAges 18–65 - NCT03478852Recruiting
Epilepsy screening and evaluation for people 8 and older
This study checks how people with known or suspected epilepsy are evaluated and followed. It may help by improving screening and understanding care for epilepsy in children and adults.
Bethesda, MarylandAges 8–110 - NCT02639325Recruiting
Seizure treatment study for people with brain tumors
This study looks at how a brain tumor-related seizure condition is handled in children and adults. It may be a good option if your seizures started soon after your brain tumor was found or is in the same brain area as your seizure symptoms.
Bethesda, MarylandAges 8–99 - NCT02107989Recruiting
MRI and brain scans before epilepsy surgery
This study collects noninvasive brain scan data (mainly MRI, sometimes MEG) from people being evaluated for focal epilepsy surgery, and from healthy volunteers. It aims to build reference “normal” brain images and improve how doctors plan and interpret epilepsy surgery evaluations.
Bethesda, MarylandAges 8–120 - NCT06908356RecruitingPhase 2
Testing PRAX-628 for focal or tonic-clonic seizures
This study tests an experimental pill called PRAX-628 for adults whose seizures are not fully controlled by current medications. It aims to see if the drug is safe and effective at reducing seizures.
Bethesda, MarylandAges 18–75 - NCT07287163Enrolling by invitationPhase 3
Long-term study of vormatrigine for epilepsy
This trial is for adults with epilepsy who have already taken vormatrigine in a previous study or through a special access program. It aims to collect ongoing safety and effectiveness information.
Bethesda, MarylandAges 18–85 - NCT06265103Recruiting
Epilepsy learning healthcare system registry
This is a registry study that collects information from people being treated for epilepsy at participating healthcare centers. The goal is to improve care by learning from real-world patient data.
Bowie, MarylandAges Any age - NCT05289934Recruiting
Recorded music to see how it affects seizures
This study is testing whether listening to recorded music can change seizure activity and brain-wave patterns in children monitored in an epilepsy center. Your child might benefit by helping researchers learn how music could affect seizures during close observation.
Baltimore, MarylandAges 4–17 - NCT04274179RecruitingPhase 3
Ketogenic diet for children with new childhood absence seizures
This trial tests whether a high-fat, low-carbohydrate (ketogenic) diet can reduce absence seizures in children who are newly diagnosed. It may help some kids by changing how the brain uses energy, but participation requires close diet monitoring and follow-up.
Baltimore, MarylandAges 3–12 - NCT06391294Enrolling by invitation
Brain stimulation study for language mapping during awake surgery
This study uses gentle electrical stimulation on the brain during awake surgery to understand how language works. It's for people having brain tumor removal or epilepsy monitoring who can speak English and do not have serious speech or thinking problems.
Baltimore, MarylandAges 18–80 - NCT06369571Enrolling by invitationPhase 1/Phase 2
Improving heart health in adults with epilepsy on a modified Atkins diet
This study tests whether a statin medication (atorvastatin) can help lower cholesterol and improve heart health in adults with epilepsy who have been on a modified Atkins diet for a year or more. It may be a good fit if you have high cholesterol and are not already on a statin or have had heart problems.
Baltimore, MarylandAges 18 years+ - NCT07594652RecruitingPhase 4
ADHD Treatment for Children With Epilepsy
This study tests whether a specific ADHD medication (Jornay PM) is safe and helpful for children who have both epilepsy and ADHD. Researchers want to see if treating ADHD can improve focus and behavior without making seizures worse.
Baltimore, MarylandAges 6–17
Hear when a new Epilepsy trial opens near Washington, D.C., DC
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Epilepsy trials in other cities
Where these studies are running near Washington, D.C.
Institutions with a site for the recruiting epilepsy studies listed above.
- National Institutes of Health Clinical Center · 7 studies
- Johns Hopkins University · 4 studies
- Mid-Atlantic Epilepsy and Sleep Center · 4 studies
- Javara / Privia Medical Group · 2 studies
- Johns Hopkins Hospital · 2 studies
- Research Site · 2 studies
- Epilepsy Foundation
- George Washington University Hospital
What taking part in a epilepsy study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Common questions
- Are there epilepsy clinical trials near Washington, D.C.?
- Yes. We're currently tracking 21 recruiting epilepsy studies with a site near Washington, D.C., each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a epilepsy study near Washington, D.C.?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Washington, D.C. to take part?
- Not necessarily. These studies have a site near Washington, D.C., but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a epilepsy trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New epilepsy studies open near Washington, D.C. regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.