Clinical trials · Boston, MA
Epilepsy clinical trials in Boston
We’re tracking 31 recruiting epilepsy studies with a site in or near Boston — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Boston
- NCT06265103Recruiting
Epilepsy learning healthcare system registry
This is a registry study that collects information from people being treated for epilepsy at participating healthcare centers. The goal is to improve care by learning from real-world patient data.
Boston, MassachusettsAges Any age - NCT05718817Enrolling by invitationPhase 3
Long-term study of XEN1101 for people with epilepsy
This study gives XEN1101 in an open-label way (everyone knows they’re getting the drug) to people who finished earlier epilepsy studies. It aims to see how the treatment continues to work and whether it’s safe over the long term.
Boston, MassachusettsAges 12 years+ - NCT06700811RecruitingPhase 1
Ketogenic diet to prevent infant seizures in genetic epilepsy
This trial tests whether starting a special high-fat diet (ketogenic diet) early can prevent epileptic spasms in babies with genetic epilepsy. It uses a specific formula called KetoVie and is for infants under 9 months old.
Boston, MassachusettsAges birth–9 months - NCT06967727Recruiting
Registry study for epilepsy and movement disorders
This study is creating a registry to track the health of people who have specific genetic changes that cause epilepsy and uncontrolled movements (dyskinesia). It may help researchers better understand these conditions and how they change over time.
Boston, MassachusettsAges birth–30 years - NCT05406349Recruiting
Study of brain activity for space memory using epilepsy implants
This study looks at how your brain represents locations in space, including how it relates to you (beyond your “self”). It uses special epilepsy-related implants or procedures to record brain activity, which may help researchers understand spatial thinking.
Boston, MassachusettsAges 18–70 - NCT05944692Recruiting
Tripolar EEG test during seizure monitoring
This study checks whether a new type of EEG recording (a brain wave test) can detect seizure activity in people with epilepsy. You may join if you are already scheduled for routine and video EEG testing (and possibly inpatient monitoring) as part of your clinical care, including a brain MRI.
Boston, MassachusettsAges 6 years+ - NCT06585605Recruiting
Study of epilepsy and movement disorder genes in children
This study looks at children with epilepsy and movement disorders to better understand the genes involved. It aims to help doctors recognize and treat these conditions more effectively.
Boston, MassachusettsAges birth–18 years - NCT07110337Recruiting
Diagnosing epilepsy to help guide treatment
This trial tests a new device to help diagnose epilepsy in people whose previous EEG brain monitoring did not give clear answers. If you have drug-resistant epilepsy with at least one seizure a month on average, this study may help find better treatment options.
Boston, MassachusettsAges 18–75 - NCT06593951Recruiting
EPM1 natural history study
This study will follow people with EPM1 over time to better understand the disease. It is a registry, meaning you will share information through video calls and questionnaires, with no experimental treatments involved.
Boston, MassachusettsAges Any age - NCT07110454Recruiting
Long-term follow-up study for epilepsy monitoring implant
This study follows people who previously enrolled in the DETECT study and had a Minder device implanted to monitor brain activity. The goal is to see how the device performs over a longer period of time.
Boston, MassachusettsAges 18–75 - NCT06443463Enrolling by invitationPhase 2
Long-term safety of BHV-7000 in epilepsy
This study checks the long-term safety of BHV-7000 for people who already completed an earlier trial with this drug. You keep taking the same medicine while doctors watch for any side effects over time.
Boston, MassachusettsAges 18–75 - NCT06275685Recruiting
Forecasting seizures with a smart wearable
This study tests if a smart wristband called EmbracePlus can predict seizures. You wear the device and track your seizures to see if it can warn you ahead of time.
Boston, MassachusettsAges 6 years+ - NCT06585618Recruiting
Pediatric Deep Brain Stimulation Registry
This study creates a list of children who already have or plan to get Deep Brain Stimulation (DBS) to see how it helps with movement problems. Joining helps doctors learn more about how DBS works in kids.
Boston, MassachusettsAges birth–18 years - NCT03868293Recruiting
Low-intensity ultrasound for drug-resistant temporal lobe seizures
This pilot study tests whether low-intensity focused ultrasound can reduce seizures in adults whose temporal lobe epilepsy hasn’t improved with at least two anti-seizure medicines. You may be asked to track seizure timing and undergo brain imaging before and during the study.
Boston, MassachusettsAges 18 years+ - NCT06934356Recruiting
Awareness and brain arousal study
This study looks at how your brain becomes aware of things—like sounds and images—by measuring pupil size and brain activity. Healthy people may have an MRI; epilepsy patients with special brain electrodes already implanted can also join a part of the study.
Boston, MassachusettsAges 13 years+ - NCT05104983RecruitingPhase 2
Sirolimus to prevent first seizures in babies with TSC
This Phase 2 study tests whether sirolimus (a targeted medicine) can stop or slow the start of seizures in very young babies diagnosed with tuberous sclerosis complex (TSC). If seizures are prevented early, it may also help protect early brain development.
Boston, MassachusettsAges 1 day–6 months - NCT06388707RecruitingPhase 1/Phase 2
Ultrasound brain stimulation for drug-resistant epilepsy
This trial tests a low-intensity focused ultrasound device that aims to calm overactive brain areas causing seizures. It's for people whose seizures are not controlled by medication.
Boston, MassachusettsAges 18 years+ - NCT06701084Recruiting
Genetic Causes of Infant Epilepsy at Boston Children's
This study looks at the genetic causes of epilepsy that starts in babies under 1 year old. It aims to learn how a genetic diagnosis might help guide care.
Boston, MassachusettsAges Any age - NCT06063850RecruitingPhase 1/Phase 2
Gene therapy for adults with hard-to-control epilepsy
This trial tests a one-time gene therapy (AMT-260) for adults whose seizures start in one area of the brain (the temporal lobe) and aren't controlled by medication. The goal is to see if it's safe and reduces seizure frequency.
Boston, MassachusettsAges 18–75 - NCT07145489Recruiting
Infrared light therapy for seizures
This trial tests whether shining a special infrared light on the scalp can reduce seizures in adults with epilepsy that is not controlled by standard medications. You would receive the light treatments and keep a diary of your seizures.
Boston, MassachusettsAges 18 years+ - NCT05222594Recruiting
Brain language study using electrodes during epilepsy care
This study looks at how the brain processes language using recordings from electrodes placed during epilepsy treatment. If you’re already being considered for this type of brain monitoring, the study’s tasks may help researchers better understand language function in the brain.
Boston, MassachusettsAges 18–85 - NCT00041600Recruiting
Brain Development and Genetic Study for Family Members
This research study investigates how genetic factors affect brain development and function in families where members have brain malformations, intellectual disability, or autism. Researchers hope to identify genetic causes that could lead to better understanding and future treatments.
Boston, MassachusettsAges Any age - NCT01858285Recruiting
Genetics study for children with epilepsy
This study looks for genetic (inherited DNA) causes of epilepsy in children. It may help your family better understand what could be driving seizures, even if the cause isn’t known yet.
Boston, MassachusettsAges Any age - NCT04419272RecruitingPhase 4
Methylphenidate for thinking problems in adults with focal seizures
This trial studies whether methylphenidate (a stimulant medicine) can improve thinking and memory problems related to epilepsy. You may be kept on your usual seizure medicines, and your thinking will be tested over about 16 weeks.
Boston, MassachusettsAges 18 years+
Hear when a new Epilepsy trial opens near Boston, MA
We’ll email you when one opens near Boston, MA — at most once a week, no account needed, unsubscribe anytime.
Epilepsy trials in other cities
Where these studies are running near Boston
Institutions with a site for the recruiting epilepsy studies listed above.
- Boston Children's Hospital · 10 studies
- Massachusetts General Hospital · 6 studies
- Brigham and Women's Hospital · 4 studies
- Beth Israel Deaconess Medical Center · 3 studies
- Boston Clinical Trials
- Boston University
- Empatica
- University of Massachusetts Chan Medical School
What taking part in a epilepsy study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting epilepsy studies in Massachusetts.
Common questions
- Are there epilepsy clinical trials near Boston?
- Yes. We're currently tracking 31 recruiting epilepsy studies with a site near Boston, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a epilepsy study near Boston?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Boston to take part?
- Not necessarily. These studies have a site near Boston, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a epilepsy trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New epilepsy studies open near Boston regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.