Clinical trials
Focused Ultrasound clinical trials
Below are recruiting focused ultrasound clinical trials, each written for real people, not researchers. We’re tracking 113 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03342625Recruiting
Focused ultrasound treatment for certain breast tumors
This trial tests whether high-intensity focused ultrasound (a targeted heat treatment) can treat some types of breast tumors and potentially reduce the need for more invasive surgery. It may help people who have specific tumor features and who are able to safely undergo MRI and the required positioning.
BordeauxAges 18 years+ - NCT04549688Recruiting
Active surveillance with focused ultrasound for prostate cancer
This trial studies whether a high-intensity focused ultrasound treatment can help people with localized prostate cancer while still avoiding traditional full-dose treatment for some patients. It may be an option for certain intermediate-risk cases where the cancer is confined to the prostate.
Tønsberg, VestfoldAges 18–80 - NCT07513844Recruiting
Ultrasound Treatment for Huntington's Disease Movement Symptoms
This trial tests a new focused ultrasound technique aimed at reducing involuntary movements (chorea) in people with Huntington's disease. The treatment targets a specific brain region and may help improve movement control and quality of life.
Fuzhou, FujianAges 18–75 - NCT05303415Recruiting
Low-intensity ultrasound study during brain MRI
This study tests how low-power focused ultrasound changes brain signals measured during MRI. You may help researchers understand how ultrasound can affect brain activity, even if you don’t have a known brain condition.
Roanoke, VirginiaAges 18–65 - NCT06453109Recruiting
Focused ultrasound for chronic back pain with opioid use
This study tests whether focused ultrasound (a non-invasive treatment using sound waves) can help people with chronic back pain who also have opioid use disorder and anxiety. It aims to find a better way to manage pain without relying on opioids.
Washington D.C., District of ColumbiaAges 18–75 - NCT07277309Recruiting
Recovery after brain injury using focused ultrasound
This study tests whether focused ultrasound can help people recover from a brain injury that has left them with a disorder of consciousness. The treatment involves a non-invasive technique that uses sound waves to stimulate brain activity.
Boston, MassachusettsAges 18–79 - NCT05610852Recruiting
Surgery through the bladder opening versus focused ultrasound for prostate cancer
This trial compares two ways to treat early prostate cancer: a single small surgery through the bladder versus high-intensity focused ultrasound (HIFU). It aims to see which approach works better while keeping side effects and recovery acceptable.
Cleveland, OhioAges 19 years+ - NCT05620290RecruitingPhase 1
MR-guided ultrasound plus radiation to help skin cancer respond
This Phase 1 study tests a new way to make radiation work better using MRI-guided focused ultrasound. It focuses on improving treatment for malignant melanoma and other skin cancers, while checking safety and how patients experience treatment.
Toronto, OntarioAges 18 years+ - NCT06405074Recruiting
Ultrasound for Smoking Cessation in Veterans
This study tests if a gentle ultrasound aimed at a specific part of the brain (the insula) can help veterans who smoke tobacco reduce or quit smoking. The research is for veterans who smoke heavily and are motivated to think about quitting but are not currently in treatment.
Washington D.C., District of ColumbiaAges 18–75 - NCT06036199Recruiting
Focused ultrasound for movement problems in cerebral palsy
This trial tests if focused ultrasound can help reduce uncontrolled movements in children and young adults with cerebral palsy caused by a lack of oxygen at birth. It may offer an option for those whose current medications aren't working well enough.
Washington D.C., District of ColumbiaAges 8–22 - NCT06816511Enrolling by invitation
Focused ultrasound study for hard-to-treat OCD
This trial tests if a non-invasive ultrasound treatment can help people with obsessive-compulsive disorder (OCD) that hasn't improved with standard therapies. You must have had OCD for at least five years, have severe symptoms, and have tried multiple medications and cognitive-behavioral therapy without enough benefit.
TaipeiAges 18–65 - NCT07734623Recruiting
Ultrasound treatment for severe opioid or amphetamine use disorder
This trial tests a low-intensity focused ultrasound treatment for people with severe opioid or amphetamine use disorder. The ultrasound targets a part of the brain linked to addiction, and the goal is to see if it is safe and helpful.
TaipeiAges 20–50 - NCT06906211Recruiting
Ultrasound for chronic back pain in veterans
This trial tests if a gentle ultrasound treatment to a specific part of the brain can help veterans with chronic back pain. It aims to see if targeting the insula can reduce pain that spreads to other areas of the body.
Washington D.C., District of ColumbiaAges 21–75 - NCT04063514Enrolling by invitation
MRI-focused ultrasound study of blood-brain barrier in low-grade glioma
This study uses special imaging during routine MRI scans to check how well the blood-brain barrier lets substances pass in people with low-grade brain tumors. It may help researchers better measure and track treatment effects over time.
Santa Monica, CaliforniaAges 18 years+ - NCT07343986RecruitingPhase 1
Ultrasound and Immunotherapy for Newly Diagnosed Brain Cancer
This trial tests whether a special ultrasound (LIFU) can open the blood-brain barrier to help an immunotherapy drug (cetuximab) reach glioblastoma tumors better. It is for people with a specific type of glioblastoma that has not been treated yet and that has a certain protein called EGFR.
Charlottesville, VirginiaAges 18–70 - NCT07168850Recruiting
Focused Ultrasound for Dystonia of Arms or Legs
This study tests whether focused ultrasound, a noninvasive treatment that uses sound waves to target a small area in the brain, can improve limb dystonia that has not been helped by medications or Botox injections. It is a possible option for people whose dystonia affects their arms or legs and who are looking for another treatment without surgery.
Mestre, (Venice)Ages 18–80 - NCT07172295Recruiting
Low-intensity focused ultrasound for hand tremor
This study uses low-intensity focused ultrasound to stimulate a deep brain area and reduce hand tremors. It is for people with Parkinson's disease, essential tremor, or dystonic tremor whose medications don't work well enough.
Hsinchu, Hsinchu CityAges 18–80 - NCT07220005Recruiting
Ultrasound brain stimulation for arm weakness after stroke
This study tests a new non-invasive therapy using low-intensity focused ultrasound to stimulate the brain area affected by a stroke, which may help improve arm weakness in people who have had a stroke more than 6 months ago.
Durham, North CarolinaAges 21 years+ - NCT07791017Recruiting
Ultrasound for detecting baker's cysts in suspected deep vein thrombosis
This study tests whether a focused ultrasound of the back of the knee can accurately detect Baker's cysts (a benign fluid-filled sac) in people who have symptoms that might suggest a blood clot. It aims to improve diagnosis and avoid unnecessary treatments.
AarhusAges 18 years+ - NCT07664176RecruitingPhase 1
Focused ultrasound plus nivolumab for children with brain tumors
This trial tests if combining focused ultrasound (which opens the blood-brain barrier) with the immunotherapy drug nivolumab can treat relapsed or progressive brainstem gliomas and other high-grade brain tumors in children and young adults.
Washington D.C., District of ColumbiaAges 3–25 - NCT07179328RecruitingPhase 1
Focused ultrasound for glioblastoma during standard chemo
This trial tests whether focused ultrasound can safely open the blood-brain barrier to help your chemotherapy work better. It is for people with glioblastoma who have already completed standard surgery and chemo-radiation and are now on maintenance chemo.
Toronto, OntarioAges 18–85 - NCT07076472RecruitingEarly Phase 1
Sound and drug therapy for recurrent glioblastoma
This trial tests a new approach that combines a drug (SONALA-001 or 5-ALA) with focused ultrasound to treat glioblastoma that has come back or is growing despite standard treatments. The drug makes tumor cells sensitive to sound waves, and the ultrasound waves are directed at the tumor using MRI guidance. This may help damage cancer cells while sparing healthy brain tissue.
Rochester, MinnesotaAges 18 years+ - NCT06496971RecruitingPhase 3
Testing focused ultrasound plus Avastin for recurrent glioblastoma
This study tests whether adding focused ultrasound to the standard drug Avastin (bevacizumab) can help treat recurrent glioblastoma. The ultrasound may help more of the drug reach the tumor.
TaipeiAges 18–80 - NCT06283758Recruiting
Ultrasound treatment for kidney fat to lower blood pressure
This trial tests a new ultrasound treatment that targets the fat pad around your kidney to lower blood pressure. It might be an option if your blood pressure is still high despite medication and you meet the size requirements for the fat pad.
Nanjing, JiangsuAges 18–65
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Common questions
- Are there clinical trials for focused ultrasound?
- Yes. Clin2 currently lists 113 recruiting focused ultrasound studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a focused ultrasound trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a focused ultrasound trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.