Clinical trials
Functional Impairment clinical trials
Below are recruiting functional impairment clinical trials, each written for real people, not researchers. We’re tracking 135 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05701852Recruiting
Study brain scans during tasks in chronic nerve pain
This study looks at how brain activity changes in people with long-lasting nerve pain using an MRI scan while you do simple behavioral tasks. It may help researchers understand brain function in chronic neuropathic pain and how it affects day-to-day abilities.
ParisAges 18 years+ - NCT06623630RecruitingPhase 1
Carvykti with special radiation and chemo for kidney patients
This trial tests adding total body radiation and a chemotherapy drug (cyclophosphamide) before the standard Carvykti cell therapy for multiple myeloma patients who have kidney problems. The goal is to see if this approach is safe and effective for people with reduced kidney function.
St Louis, MissouriAges 18 years+ - NCT07277166Recruiting
Robot-assisted walking training for chronic burn survivors
This study tests whether walking with a mobile robot (a device that helps move your legs) can improve your walking ability. It is for people who still have trouble walking more than 6 months after a serious burn on their legs.
SeoulAges 19–65 - NCT07315360RecruitingPhase 1
How a new medicine works in people with reduced kidney function
This study tests how the body processes the experimental medicine PF-07328948 in people with different levels of kidney function. It may help find the right dose for people with kidney disease.
Lake Forest, CaliforniaAges 18–80 - NCT07322016RecruitingPhase 1
Testing an experimental drug in people with healthy or reduced kidney function
This trial tests a new tablet, HRS-1301, to see how it is processed by the body in people with different levels of kidney function. It aims to help doctors understand dosing for patients with kidney impairment.
Chengdu, SichuanAges 18–65 - NCT07366697Recruiting
Using wrist sensors to measure daily arm use after stroke
This study tests whether wearing small activity monitors on both wrists for 3 days can better measure how stroke affects daily two-handed tasks. It aims to improve understanding of real-world arm function.
LeuvenAges 18–80 - NCT07372066Recruiting
Brain exercise group for seniors with memory concerns
This trial tests a cognitive stimulation therapy group for older adults living in residential homes who have mild cognitive impairment or dementia. The goal is to see if group activities can help keep the mind active and improve quality of life.
Hong Kong, Hong KongAges 60 years+ - NCT07443059RecruitingPhase 1
Zovaglutide study in people with kidney problems
This study tests an investigational drug called Zovaglutide (ZT002) in people with different levels of kidney function, from normal to severely impaired. The goal is to see how the drug is processed by the body and how safe it is for people with kidney problems.
Xiamen, FujianAges 18–75 - NCT07250633RecruitingPhase 1
Study of Vorasidenib in severe liver disease and healthy volunteers
This trial tests how the drug vorasidenib behaves in people with severe liver problems compared to healthy volunteers. It helps doctors understand if the drug needs different dosing for patients with liver disease.
Chandler, ArizonaAges 18–75 - NCT07643155RecruitingPhase 1
Safety study of inhaled treprostinil in people with liver disease
This early-stage study tests how the body processes a new inhaled breathing medication (treprostinil) and whether it's safe in people with normal liver function and those with chronic liver disease. The goal is to understand if the medication works differently depending on liver health.
Lake Forest, CaliforniaAges 18–70 - NCT05563259Enrolling by invitation
Brain and memory testing in fatty liver disease
This study checks how well your brain and memory work in people with non-alcoholic fatty liver disease. It also looks at brain function with special assessments, which may help researchers understand what changes happen with this condition.
Nanjing, JiangsuAges 20–75 - NCT06634147Recruiting
Exercise program to prevent decline in hospitalized older adults
This study is testing a gentle exercise program for older adults (75+) while they are in the hospital. The goal is to see if it helps prevent loss of strength, memory, or thinking skills.
Pamplona, NavarreAges 75 years+ - NCT06201533Recruiting
Light exercise and thinking activities for memory
This study tests if a program that combines light physical activity with simple mental tasks can help improve memory and thinking in people with mild cognitive impairment (MCI). It is for people who are not already exercising regularly and do not take memory medications.
Chiang MaiAges 60 years+ - NCT06579378Recruiting
Virtual reality sailing for memory and thinking
This study tests whether a virtual reality sailing program called 'VSail 3D' can help improve thinking and memory in older adults with mild cognitive impairment. It looks at whether the program is easy and safe to use.
Cagliari, CAAges 65 years+ - NCT07002996Recruiting
Virtual reality memory training for mild cognitive impairment
This study tests whether a special memory training program using virtual reality can improve thinking skills in people with mild cognitive impairment. It may help slow memory loss and keep your mind sharper.
Verdun, QuebecAges 55 years+ - NCT07523503Recruiting
One-sided vs. both-sides arm training after stroke
This study compares two ways of doing hand and arm exercises after stroke: practicing with just your weak arm, or practicing with both arms together. The goal is to see which approach helps you regain better movement, strength, and hand coordination.
Kot AdduAges 40–75 - NCT06682741Enrolling by invitation
Comparing exercise programs for brain health in women
This study tests whether different types of exercise training can improve thinking and memory in women. It may help find the best workout for keeping your mind sharp.
Poznan, PolandAges 50 years+ - NCT05632120Enrolling by invitation
Testing how COPD affects daily movement and participation
This study looks at how chronic obstructive pulmonary disease (COPD) may affect your body function, walking, and ability to take part in everyday life. It may help researchers understand what support or therapies could improve daily activities.
Istanbul, Fatih/İstanbulAges 35–80 - NCT07760545Recruiting
Memory screening by video before surgery
This study tests whether doing a quick memory and thinking check over video call is as reliable as doing it in person. You would take part before your scheduled surgery to help improve how cognitive health is assessed.
Vancouver, British ColumbiaAges 65 years+ - NCT07145294RecruitingPhase 1/Phase 2
Stem cell therapy to improve thinking after stroke
This trial tests whether tiny particles from stem cells can help people recover thinking and memory after a recent stroke. Doctors will check if the treatment is safe and if it boosts brain function.
ShanghaiAges 18 years+ - NCT06867198Recruiting
Peanuts for heart, brain, and gut health
This study tests whether eating peanuts can improve health markers like blood sugar, brain function, and digestion in adults with prediabetes (higher than normal blood sugar levels). You may qualify if you are between 20-59 years old, have prediabetes, and a BMI in the overweight to obese range.
Atlanta, GeorgiaAges 20–59 - NCT07424365Recruiting
Vagus nerve stimulation for thinking skills in health and Parkinson's
This study explores whether vagus nerve stimulation (a gentle electrical pulse that travels through a nerve in your ear) can boost thinking and decision-making skills in healthy people and those with Parkinson's disease. It involves a noninvasive device that stimulates the ear, and you may participate if you meet certain health criteria.
Aurora, ColoradoAges 18–65 - NCT07547319Recruiting
Accelerated rTMS to improve cognitive function
This study tests whether repeated magnetic pulses to the brain (called rTMS) can help improve thinking and memory in older adults with mild to moderate cognitive decline. The treatment is non-invasive and may help slow cognitive changes.
San Francisco, CaliforniaAges 50–90 - NCT05028712Recruiting
Multi-sensory rehab program for people with ultra low vision
This trial tests a rehabilitation program using multiple senses to help people with very low vision function more independently. It may help you learn new skills for daily life by using vision plus other senses.
New York, New YorkAges 12–99
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Common questions
- Are there clinical trials for functional impairment?
- Yes. Clin2 currently lists 135 recruiting functional impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a functional impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a functional impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.