Clinical trials
Functional Impairment clinical trials
Below are recruiting functional impairment clinical trials, each written for real people, not researchers. We’re tracking 133 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07315360RecruitingPhase 1
How a new medicine works in people with reduced kidney function
This study tests how the body processes the experimental medicine PF-07328948 in people with different levels of kidney function. It may help find the right dose for people with kidney disease.
Lake Forest, CaliforniaAges 18–80 - NCT07269301RecruitingPhase 1
Liver function and study drug processing
This study looks at how the medicine PF-07328948 is processed by people with different levels of liver function. It includes both healthy people and those with stable liver disease (classified as mild, moderate, or severe). The goal is to see if the liver condition affects how the drug works in the body.
Lake Forest, CaliforniaAges 18–74 - NCT07277166Recruiting
Robot-assisted walking training for chronic burn survivors
This study tests whether walking with a mobile robot (a device that helps move your legs) can improve your walking ability. It is for people who still have trouble walking more than 6 months after a serious burn on their legs.
SeoulAges 19–65 - NCT06623630RecruitingPhase 1
Carvykti with special radiation and chemo for kidney patients
This trial tests adding total body radiation and a chemotherapy drug (cyclophosphamide) before the standard Carvykti cell therapy for multiple myeloma patients who have kidney problems. The goal is to see if this approach is safe and effective for people with reduced kidney function.
St Louis, MissouriAges 18 years+ - NCT05701852Recruiting
Study brain scans during tasks in chronic nerve pain
This study looks at how brain activity changes in people with long-lasting nerve pain using an MRI scan while you do simple behavioral tasks. It may help researchers understand brain function in chronic neuropathic pain and how it affects day-to-day abilities.
ParisAges 18 years+ - NCT04297020Recruiting
Checking brain health in breast cancer survivors
This study looks at differences in brain function in people who have had breast cancer, compared with certain people without that history. It’s testing how brain health changes after breast cancer and relates to mood, thinking, and daily functioning.
Los Angeles, CaliforniaAges 35–65 - NCT07751250RecruitingPhase 1
Casdatifan in moderate liver impairment
This study looks at how a new drug, casdatifan, is processed in the body in people with moderate liver problems compared to healthy people. Understanding this helps doctors decide if the drug is safe and how to dose it for patients with liver issues.
San Antonio, TexasAges 18–84 - NCT07250633RecruitingPhase 1
Study of Vorasidenib in severe liver disease and healthy volunteers
This trial tests how the drug vorasidenib behaves in people with severe liver problems compared to healthy volunteers. It helps doctors understand if the drug needs different dosing for patients with liver disease.
Chandler, ArizonaAges 18–75 - NCT07643155RecruitingPhase 1
Safety study of inhaled treprostinil in people with liver disease
This early-stage study tests how the body processes a new inhaled breathing medication (treprostinil) and whether it's safe in people with normal liver function and those with chronic liver disease. The goal is to understand if the medication works differently depending on liver health.
Lake Forest, CaliforniaAges 18–70 - NCT07523503Recruiting
One-sided vs. both-sides arm training after stroke
This study compares two ways of doing hand and arm exercises after stroke: practicing with just your weak arm, or practicing with both arms together. The goal is to see which approach helps you regain better movement, strength, and hand coordination.
Kot AdduAges 40–75 - NCT07002996Recruiting
Virtual reality memory training for mild cognitive impairment
This study tests whether a special memory training program using virtual reality can improve thinking skills in people with mild cognitive impairment. It may help slow memory loss and keep your mind sharper.
Verdun, QuebecAges 55 years+ - NCT06634147Recruiting
Exercise program to prevent decline in hospitalized older adults
This study is testing a gentle exercise program for older adults (75+) while they are in the hospital. The goal is to see if it helps prevent loss of strength, memory, or thinking skills.
Pamplona, NavarreAges 75 years+ - NCT06682741Enrolling by invitation
Comparing exercise programs for brain health in women
This study tests whether different types of exercise training can improve thinking and memory in women. It may help find the best workout for keeping your mind sharp.
Poznan, PolandAges 50 years+ - NCT06201533Recruiting
Light exercise and thinking activities for memory
This study tests if a program that combines light physical activity with simple mental tasks can help improve memory and thinking in people with mild cognitive impairment (MCI). It is for people who are not already exercising regularly and do not take memory medications.
Chiang MaiAges 60 years+ - NCT07760545Recruiting
Memory screening by video before surgery
This study tests whether doing a quick memory and thinking check over video call is as reliable as doing it in person. You would take part before your scheduled surgery to help improve how cognitive health is assessed.
Vancouver, British ColumbiaAges 65 years+ - NCT07145294RecruitingPhase 1/Phase 2
Stem cell therapy to improve thinking after stroke
This trial tests whether tiny particles from stem cells can help people recover thinking and memory after a recent stroke. Doctors will check if the treatment is safe and if it boosts brain function.
ShanghaiAges 18 years+ - NCT07424365Recruiting
Vagus nerve stimulation for thinking skills in health and Parkinson's
This study explores whether vagus nerve stimulation (a gentle electrical pulse that travels through a nerve in your ear) can boost thinking and decision-making skills in healthy people and those with Parkinson's disease. It involves a noninvasive device that stimulates the ear, and you may participate if you meet certain health criteria.
Aurora, ColoradoAges 18–65 - NCT06867198Recruiting
Peanuts for heart, brain, and gut health
This study tests whether eating peanuts can improve health markers like blood sugar, brain function, and digestion in adults with prediabetes (higher than normal blood sugar levels). You may qualify if you are between 20-59 years old, have prediabetes, and a BMI in the overweight to obese range.
Atlanta, GeorgiaAges 20–59 - NCT07547319Recruiting
Accelerated rTMS to improve cognitive function
This study tests whether repeated magnetic pulses to the brain (called rTMS) can help improve thinking and memory in older adults with mild to moderate cognitive decline. The treatment is non-invasive and may help slow cognitive changes.
San Francisco, CaliforniaAges 50–90 - NCT07511270Recruiting
Predicting thinking skills from speech using AI
This study uses an AI tool to analyze short stories you tell aloud, to see if it can predict your thinking and memory test scores. It may help develop a simpler way to check cognitive health.
TaoyuanAges 50 years+ - NCT07141030RecruitingPhase 1
Study of GZR18 in people with and without kidney problems
This trial tests how a new drug called GZR18 (given as an injection) affects the body in people with different levels of kidney function. It aims to find the right dose and check for side effects, which could help guide treatment for people with kidney issues.
BeijingAges 18–75 - NCT07121660Recruiting
Changes after spine or hip surgery in children
This study looks at how children with severe neurological impairments recover after major spine or hip surgery. It compares their recovery to children without these impairments, to understand different recovery paths.
Vancouver, British ColumbiaAges 5–18 - NCT05028712Recruiting
Multi-sensory rehab program for people with ultra low vision
This trial tests a rehabilitation program using multiple senses to help people with very low vision function more independently. It may help you learn new skills for daily life by using vision plus other senses.
New York, New YorkAges 12–99 - NCT07033221Recruiting
Balance and inner ear function in obesity
This study looks at how obesity affects your sense of balance (vestibular function). It compares people with obesity who are candidates for weight-loss surgery to people without obesity, to see if weight affects balance.
Istanbul, KüçükçekmeceAges 18–60
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Common questions
- Are there clinical trials for functional impairment?
- Yes. Clin2 currently lists 133 recruiting functional impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a functional impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a functional impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.