Clinical trials
Functional Impairment clinical trials
Below are recruiting functional impairment clinical trials, each written for real people, not researchers. We’re tracking 134 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07315334Recruiting
Understanding nerve damage from chemotherapy
This study looks at how chemotherapy-related nerve damage affects daily activities like walking and standing. It includes people who currently have or have had nerve-damaging chemotherapy and are experiencing nerve pain or weakness.
SalzburgAges 18 years+ - NCT05856552Recruiting
Study on how depression affects older women’s health
This study looks at how depression impacts the health and social life of older women. It aims to understand the effects of depression so care and support can improve.
Chennai, Tamil NaduAges 55 years+ - NCT07528261Recruiting
Support Group for Family Caregivers of Stroke Survivors
This study tests whether a support group using acceptance and commitment therapy (a type of counseling that helps people cope with stress) can reduce caregiver burden and distress. You would meet online with other people caring for stroke survivors.
Alameda, CaliforniaAges 40 years+ - NCT05131399Recruiting
Test an off-the-shelf carbon ankle brace for drop foot walking
This trial studies whether a ready-made carbon ankle-foot brace (AFO) improves walking when someone has “drop foot” (trouble lifting the front of the foot). It’s meant to help with standing and stability by supporting the ankle and foot.
AngersAges 18 years+ - NCT05624125Recruiting
Beetroot juice study for circulation problems in leg arteries
This trial tests whether drinking beetroot juice can improve how well people with peripheral artery disease (PAD) can function and walk. It’s looking at circulation-related measurements in the legs and how you do on walking tests.
Chicago, IllinoisAges 50 years+ - NCT06133244Recruiting
Hand function in systemic sclerosis
This study looks at how systemic sclerosis (a condition that can cause hardening of the skin) affects hand function. It aims to understand the problems people face and find better ways to help.
UtrechtAges 18 years+ - NCT06137196Recruiting
Lung function risks after severe pneumonia in AIDS patients
This study looks at why some people with AIDS who recover from severe pneumonia later have trouble breathing. Researchers want to find risk factors so they can help prevent lung damage.
Guangzhou, GuangdongAges 18–65 - NCT06260111Recruiting
Laser therapy for mouth sores during stem cell transplant
This study tests whether a special light therapy (photobiomodulation) can reduce painful mouth sores and help you eat, drink, and speak better during a stem cell transplant. It is for adults with blood cancers who are having a stem cell transplant.
Santiago, Santiago MetropolitanAges 18–65 - NCT06345976Recruiting
How albinism affects daily vision and activities
This study is for adults with any type of albinism. It looks at how albinism affects your everyday vision and activities through a simple questionnaire.
ParisAges 18 years+ - NCT06476470Recruiting
Taiwan ILD registry for understanding lung disease
This registry is gathering information from people with different types of interstitial lung disease (ILD) across Taiwan. It aims to better understand the disease and improve future care.
TaichungAges 18 years+ - NCT07190092Recruiting
Brain stimulation for post-stroke muscle stiffness and movement
This study tests a new type of brain stimulation (deep anterior cerebellar stimulation) to see if it can reduce muscle stiffness and improve movement in people who had a stroke 9–36 months ago and still have tightness or weakness that hasn't gotten better with therapy.
BydgoszczAges 18 years+ - NCT07348081Recruiting
Digital support program for caregivers of ER patients
This trial tests a digital program that helps caregivers coordinate and monitor care for adults leaving the emergency department. It may reduce stress and make caring easier.
ParisAges 18 years+ - NCT07287527Recruiting
Light therapy for memory and brain health
This study tests whether a type of light therapy called photobiomodulation can improve brain connections and thinking abilities in people with mild memory problems.
IstanbulAges 55 years+ - NCT07694869RecruitingPhase 1
Study of ammoxetine tablets in people with moderate kidney problems
This trial tests how a new drug called ammoxetine works in people with moderate kidney impairment compared to those with normal kidney function. It aims to find the right dose and understand how the drug is processed by the body.
Hefei, AnhuiAges 18–75 - NCT06598163Recruiting
Cognitive training app for mild memory problems
This trial tests a mobile app called Five Lives MED to see if it can improve thinking and memory in people with mild cognitive impairment (MCI). You can join if you have MCI and are 50 or older.
Paris, Île-de-France RegionAges 50 years+ - NCT07519798Enrolling by invitation
Brain Stimulation for Memory Problems in Older Adults
This study tests a new, non-invasive brain stimulation technique called transcranial temporal interference stimulation to see if it can improve memory and thinking skills in older adults with mild cognitive impairment (early memory loss that isn't yet dementia). Participants will receive the stimulation treatment and have their cognitive function monitored over time.
Shanghai, Shanghai MunicipalityAges 60–80 - NCT07422857RecruitingPhase 3
A PET scan for detecting signs of Alzheimer's
This trial uses a new type of PET scan to look for specific proteins in the brain that are linked to Alzheimer's disease. It will help doctors see how these proteins relate to cognitive decline and compare scans from people with normal thinking to those with memory problems.
Wuhan, HubeiAges 50 years+ - NCT07244809Recruiting
Study on stress history and blood vessel health in young adults
This study tests whether early-life stress affects blood vessel function in young adults by looking at a type of cell stress called oxidative stress. It involves measuring how well your blood vessels work and may help understand why some people have higher heart risks.
Iowa City, IowaAges 18–29 - NCT07269301RecruitingPhase 1
Liver function and study drug processing
This study looks at how the medicine PF-07328948 is processed by people with different levels of liver function. It includes both healthy people and those with stable liver disease (classified as mild, moderate, or severe). The goal is to see if the liver condition affects how the drug works in the body.
Lake Forest, CaliforniaAges 18–74 - NCT07662135RecruitingPhase 3
A study of elecoglipron for type 2 diabetes with kidney problems
This trial tests a new medicine called elecoglipron to see if it helps control blood sugar in people with type 2 diabetes who also have reduced kidney function. You would continue taking your current SGLT2i medication (like dapagliflozin).
Peoria, ArizonaAges 18 years+ - NCT07741292RecruitingPhase 4
Kidney health study for older adults not on dialysis
This study tests whether a traditional Chinese medicine called Niaoduqing Granules can help improve kidney function in people over 60 with chronic kidney disease. It may offer a new way to manage the condition without dialysis.
Shanghai, Shanghai MunicipalityAges 61 years+ - NCT04196244RecruitingPhase 4
IV-contrast CT vs no-contrast CT for urgent abdominal pain
This study compares two types of CT scans—using IV contrast dye versus not using dye—in people who need an emergency abdominal scan but have reduced kidney function. It aims to see which approach is safer and works well enough to help doctors find the cause.
EspooAges 18 years+ - NCT04297020Recruiting
Checking brain health in breast cancer survivors
This study looks at differences in brain function in people who have had breast cancer, compared with certain people without that history. It’s testing how brain health changes after breast cancer and relates to mood, thinking, and daily functioning.
Los Angeles, CaliforniaAges 35–65 - NCT05701852Recruiting
Study brain scans during tasks in chronic nerve pain
This study looks at how brain activity changes in people with long-lasting nerve pain using an MRI scan while you do simple behavioral tasks. It may help researchers understand brain function in chronic neuropathic pain and how it affects day-to-day abilities.
ParisAges 18 years+
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Common questions
- Are there clinical trials for functional impairment?
- Yes. Clin2 currently lists 134 recruiting functional impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a functional impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a functional impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.