Clinical trials
Functional Impairment clinical trials
Below are recruiting functional impairment clinical trials, each written for real people, not researchers. We’re tracking 135 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07682818RecruitingPhase 1
Petrelintide in people with liver impairment
This trial tests how a drug called petrelintide is processed in people with different levels of liver function. It may help doctors understand how to dose the drug safely for patients with liver disease, including those with type 2 diabetes.
Wroclaw, PolandAges 18–70 - NCT06307652RecruitingPhase 3
Testing a new heart failure and kidney treatment combo
This study tests a new combination of two medicines (balcinrenone and dapagliflozin) for people with heart failure and reduced kidney function. The goal is to see if this combination helps improve heart and kidney health better than current treatments.
Alexander City, AlabamaAges 18–130 - NCT06404970Recruiting
A study for older veterans with frailty in primary care
This study aims to help identify and manage functional impairment and frailty in older veterans. It will test ways to improve how primary care providers screen and support veterans who may have difficulty with daily activities or overall health declines.
Philadelphia, PennsylvaniaAges 60 years+ - NCT07368166Recruiting
A study to measure PTSD-related daily life challenges in children
This trial tests a questionnaire called PTSD-iMPACT that helps measure how PTSD affects a child's daily life. It is designed for children and teens who may or may not have a PTSD diagnosis, and their caregivers.
AachenAges 7–18 - NCT07132944Recruiting
CTraC-FIT: a program for frail older veterans
This study is testing a program called CTraC-FIT, designed to help older veterans who are frail or have trouble with walking or balance. The goal is to see if it's possible to run this program and if it helps people improve their physical function.
Boston, MassachusettsAges 65 years+ - NCT05619068Recruiting
Study tracking outcomes in Moyamoya disease
This study looks at how Moyamoya disease changes over time and what predicts outcomes. It uses approved brain imaging and, likely, thinking/memory tests to understand prognosis.
Beijing, Beijing MunicipalityAges 10–60 - NCT06577415RecruitingPhase 1
Study of RAY1225 in people with reduced liver function
This study tests a new medicine called RAY1225 in people with mild or moderate liver problems compared to those with healthy livers. It helps researchers understand how the liver affects the medicine, which could lead to safer dosing.
Guangzhou, GuangdongAges 18–75 - NCT07227922RecruitingPhase 1
Study of clofutriben in people with kidney impairment
This study tests how the drug clofutriben is processed in people with moderate kidney impairment compared to those with normal kidneys. It helps determine if dose adjustments are needed in kidney patients.
Orlando, FloridaAges 18–83 - NCT06897670Recruiting
Brain blood flow patterns in mood and memory disorders
This study uses a headband with light sensors (fNIRS) to measure blood flow in the brain while you do thinking tasks. It aims to understand differences in brain activity for people with depression, bipolar disorder, or mild memory loss.
Rochester, MinnesotaAges 18 years+ - NCT07287410Recruiting
Assessing thinking and daily life in dementia and MCI
This study looks at how dementia or mild cognitive impairment affects thinking, daily living, and mood. The goal is to better understand these conditions by doing careful assessments.
Messina, MEAges 50–86 - NCT06848751Recruiting
Tubeless lung surgery for patients with weak lungs
This trial tests whether a tubeless surgery technique (no breathing tube during or after surgery) is safe and effective for people whose lungs are not working well. If you need lung surgery and have trouble breathing, this approach might help you avoid a breathing tube and a stay in the ICU.
Jinan, ShandongAges 14–85 - NCT07735910Recruiting
Binaural beats for memory in older adults with mild cognitive impairment
This trial tests whether listening to special sounds called binaural beats can help older adults with mild memory or thinking problems improve their cognitive function. If you live in a nursing home and have mild cognitive impairment (not dementia), you may be able to join.
Shenyang, LiaoningAges 60 years+ - NCT07521371Enrolling by invitation
Intranasal Insulin for Autism in Children and Young Adults
This study observes how intranasal insulin (a form of insulin delivered through the nose) affects children and young adults with autism spectrum disorder who are already using or planning to use it as part of their regular care. Researchers will track changes in behavior and social skills over about 6 months.
Spring, TexasAges 4–21 - NCT07559539Recruiting
Life after scoliosis surgery: long-term outcomes study
This research follows adults who had spine-straightening surgery (called fusion) for adolescent scoliosis in their teens. Researchers want to understand how surgery affects your daily life, physical function, and quality of life 10–25 years later.
Warsaw, Masovian VoivodeshipAges 25–40 - NCT07694843RecruitingPhase 1
Study of ammoxetine for people with mild to moderate liver problems
This trial tests how the body processes ammoxetine in people with mild or moderate liver impairment compared to people with normal liver function. It aims to find out if the drug is safe and how it works in these groups.
Suzhou, JiangsuAges 18–75 - NCT06530056Recruiting
Back mobilization for posture and lung function
This trial studies a special hands-on technique called costovertebral mobilization to see if it can improve rounded upper back posture and lung function in non-smokers with early kyphosis. It may help you breathe easier and stand taller.
IslamabadAges 20–40 - NCT06554717RecruitingPhase 2
Tesamorelin and exercise for physical function in HIV
This study tests whether adding tesamorelin to an exercise program helps older adults with HIV improve their physical function and reduce belly fat. It is designed for people who are mostly sedentary and show early signs of frailty.
Aurora, ColoradoAges 50–80 - NCT07715149RecruitingPhase 1
D-2570 study for people with and without liver issues
This trial tests how a drug called D-2570 is processed in people with different levels of liver function. It compares people with liver impairment to those with healthy livers to see how the drug moves through the body.
Bengbu, AnhuiAges 18–70 - NCT06756633Recruiting
Breathing and movement study for neuromuscular disease
This study looks at breathing, chest and belly movement, and exercise ability in people with Duchenne Muscular Dystrophy or Spinal Muscular Atrophy, as well as healthy people. The goal is to compare these functions to help understand how these diseases affect the body.
Ankara, ÇankayaAges 5–15 - NCT05847426Recruiting
Testing early hearing support using brain scans in babies
This study helps improve early hearing care by using a simple brain scan test (fNIRS) in babies with permanent hearing loss. It compares different early intervention approaches and aims to find better ways to support hearing development early on.
East Melbourne, VictoriaAges 24 years+ - NCT05756894Recruiting
Stimulation therapy to improve breathing after spinal cord injury
This trial studies a neurostimulation approach to help breathing problems after a spinal cord injury. You may be able to join if you have a certain type and level of spinal cord injury and breathing weakness, and you can safely attend study visits with caregiver support.
Chicago, IllinoisAges 18–85 - NCT05329662RecruitingPhase 2
Stem cell treatment for sexual function problems in perimenopausal women
This Phase 2 study tests an injected stem cell treatment made from body fat to improve sexual function in women who are in the perimenopause stage (not yet fully through menopause). You may qualify if your hormone and symptom levels suggest decline and you meet general health and infection-safety checks.
HanoiAges 40–65 - NCT07348926Recruiting
Family well-being & independence in rare genetic disorders
This study looks at how a child's ability to function independently affects the well-being of their family. It is for caregivers of young children (0–4 years) with rare genetic disorders who have been in physiotherapy for at least 6 months.
IstanbulAges 18–65 - NCT07282522Recruiting
Sensory and function in cervical disc herniation
This study looks at how cervical disc herniation affects sensation and daily function. If you have had neck pain for at least 3 months and have been diagnosed with cervical disc herniation, researchers want to compare your results to people without neck pain.
Iğdır, IğdirAges 18–65
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Common questions
- Are there clinical trials for functional impairment?
- Yes. Clin2 currently lists 135 recruiting functional impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a functional impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a functional impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.