Clinical trials
Functional Impairment clinical trials
Below are recruiting functional impairment clinical trials, each written for real people, not researchers. We’re tracking 135 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06089096Recruiting
Sleep apnea and memory in people with mild memory problems
This study looks at whether sleep apnea (pauses in breathing during sleep) is linked to thinking and memory in people who have mild memory problems. You will do a home sleep test and take memory tests to help researchers find this connection.
Hong KongAges 18 years+ - NCT07342868RecruitingPhase 1
Single dose study for liver health
This trial tests a single dose of an experimental drug called pevifoscorvir in people with moderate liver problems and in healthy people. It aims to see how the body processes the drug and if it is safe.
Orlando, FloridaAges 18–75 - NCT06753578Recruiting
Cognitive training for seniors with mild memory loss
This trial tests a new cognitive training program designed to improve quality of life and thinking skills in older adults living in care facilities who have mild cognitive impairment (MCI). The program uses acceptance and commitment therapy (ACT) to help participants adapt to memory challenges.
Santander, CantabriaAges 65 years+ - NCT07165002RecruitingPhase 1
Study of LY3537031 in people with and without liver problems
This trial tests how a new medicine, LY3537031, moves through the body and how safe it is for people with different levels of liver function. It includes people with normal livers and those with mild, moderate, or severe liver impairment.
KistarcsaAges 18–85 - NCT07342881RecruitingPhase 1
Single dose study of pevifoscorvir in people with kidney impairment
This study tests how a single dose of the study drug, pevifoscorvir, is processed in people with different levels of kidney function. It helps understand if the dose needs to be adjusted for people with kidney problems.
Orlando, FloridaAges 18–75 - NCT02290834Recruiting
Studying brain and thinking changes after chemotherapy in older breast cancer patients
This study looks at how chemotherapy may affect memory and thinking, using thinking tests and possibly brain imaging. It compares older breast cancer patients who do and do not get chemotherapy, plus a group of healthy older adults.
Boston, MassachusettsAges 60 years+ - NCT06407141Enrolling by invitation
Brain stimulation study for older adults with mild memory loss
This trial tests whether a harmless brain stimulation technique called TPS can improve memory and thinking in older adults with mild memory problems. You may be able to join if you have MCI, are right-handed, and are generally healthy otherwise.
Hong KongAges 50–100 - NCT07243600Recruiting
Brain Training for Memory in Mild Cognitive Impairment
This study tests a computer-based brain-training program designed to improve memory and thinking skills in older adults with mild cognitive impairment (MCI). It aims to see if these exercises can help keep the brain healthy and slow down memory decline.
Montreal, QuebecAges 65 years+ - NCT07105800Recruiting
Dance classes for thinking and movement in older adults
This study tests whether weekly dance classes can help improve thinking skills (like planning and focus) and physical abilities in older adults who have noticed some memory or mood changes. You would take part in a group dance program, and the researchers will track your progress over time.
New Taipei City, TaiwanAges 55 years+ - NCT05865093Recruiting
Check early vision changes in infants at risk for brain vision problems
This pilot study looks at early vision (what babies can see and how their eyes respond) in children who have risk factors for future “cerebral visual impairment,” meaning vision problems caused by the brain. It may help doctors spot issues earlier and better understand which early visual signs matter.
RomeAges 2 days–3 years - NCT06395558Recruiting
Online support program for cardiac arrest survivors
This trial tests if an internet-based program helps people recover after a cardiac arrest. You may qualify if you were discharged from the hospital with good brain function and can use the web.
Bologna, BolognaAges 18–80 - NCT06408103Recruiting
Brain health program for you and your caregiver
This study tests a program that combines exercise, nutrition, and mental activities for both you and your family caregiver. It aims to help keep your thinking and memory skills strong.
Bucaramanga, Santander DepartmentAges 55 years+ - NCT06852209Recruiting
Brain training with neurofeedback after a stroke
This study tests a brain-training technique called neurofeedback to see if it can improve thinking skills after a stroke. If you have ongoing memory or attention problems despite recovery, this trial may help you train your brain using real-time feedback from your own brain activity.
BordeauxAges 18–75 - NCT07733726Enrolling by invitation
Dual-Task Mouth and Memory Training for Oral Frailty
This study tests a program that combines mouth exercises with memory tasks to see if it can improve both chewing, swallowing, and thinking skills in people who have oral frailty and some memory decline.
KowloonAges 50 years+ - NCT06955494Recruiting
Smartphone brain training for memory and hearing
This study tests whether a brain-training program done on a smartphone can improve hearing, thinking, and quality of life in people with mild memory problems and hearing loss. You and a family caregiver will use the program together.
Hong KongAges 60 years+ - NCT06701630Recruiting
Italian study of daily thinking and memory scales
This study is testing new questionnaires to better understand everyday thinking and memory problems in older adults. It aims to improve how doctors identify and track conditions like mild cognitive impairment and early dementia.
Milan, MichiganAges 60 years+ - NCT07659964Recruiting
Rhythmic music and walking study for Alzheimer's
This study tests whether listening to a steady beat (rhythmic music) while walking can improve movement and brain function in people with mild Alzheimer's disease. Healthy volunteers are also needed for comparison.
Boston, MassachusettsAges 50–90 - NCT05436600Recruiting
Exercise program for people with narrowed neck arteries
This trial studies whether a supervised exercise program can improve mobility and balance in people who have narrowed carotid arteries in the neck but no stroke symptoms. If you fit the criteria, the goal is to see whether exercise helps your movement and safety without increasing risks.
Baltimore, MarylandAges 18–89 - NCT07672834Recruiting
Resistance band training for leg strength in older adults
This study tests whether using simple elastic resistance bands can help improve leg muscle strength in older adults who have weak leg muscles. It involves supervised training sessions and may help you move better and feel stronger.
LondonAges 50 years+ - NCT07287852Enrolling by invitationPhase 2
Ginkgo biloba extract for mild cognitive impairment
This trial tests whether a specific ginkgo biloba extract (EGb761) can improve thinking and memory in people with mild cognitive impairment (MCI). It also looks at changes in blood markers related to the condition.
JerusalemAges 65 years+ - NCT07404761Recruiting
Moving your arm after stroke or TBI
This study tests a device that uses mild electrical pulses and augmented reality (a computer overlay on real life) to help people who have arm or hand weakness after a recent stroke or brain injury regain movement.
HaifaAges 18 years+ - NCT04171323Recruiting
Active mind training to improve thinking and delay dementia
This study tests an “active mind” computer-based program to help improve thinking skills and possibly slow the process toward dementia. You may be randomly assigned to different program options to see which approach works best for your goals.
San Francisco, CaliforniaAges 55–89 - NCT06411561Recruiting
Boosting memory after ICU stay for older adults
This study tests a combination of activities (like cognitive training and exercise) to help older adults recover thinking and memory after a serious illness in the ICU. It may help you regain sharpness and independence after leaving the intensive care unit.
Seattle, WashingtonAges 60 years+ - NCT06672367Recruiting
Balance and gaze exercises for brain health in older adults
This study looks at whether adding gaze stability exercises (eye and head movements) to balance training can improve thinking, balance, and walking steadiness in older adults with mild memory problems. It may help those who can follow simple instructions and join in physical activity.
IslamabadAges 55 years+
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Common questions
- Are there clinical trials for functional impairment?
- Yes. Clin2 currently lists 135 recruiting functional impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a functional impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a functional impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.