Clinical trials
Functionality clinical trials
Below are recruiting functionality clinical trials, each written for real people, not researchers. We’re tracking 2,474 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07723924RecruitingPhase 2
Plecanatide for constipation in children and teens
This study tests a new medicine called plecanatide for children and teens with functional constipation. It aims to see if it helps improve bowel movements compared to a placebo (a pill with no medicine).
Birmingham, AlabamaAges 6–17 - NCT07863908Recruiting
Sepsis and acute respiratory distress syndrome study in China
This study looks at patients with sepsis (a severe infection that affects organs) and acute respiratory distress syndrome (ARDS, a serious lung condition) to learn more about these illnesses and improve care.
Xiamen, FujianAges 18 years+ - NCT05714241Recruiting
Blood tests to study heart pain with blocked-unblocked arteries
This study looks at blood “biomarkers” and platelet function to better understand INOCA (heart-related chest pain despite no major artery blockage). You may be eligible if you have INOCA and are already taking aspirin, and if you haven’t taken certain blood-thinner or platelet-altering medicines recently.
RomeAges 18 years+ - NCT06261645Recruiting
Exercise program for non-traumatic shoulder instability
This study tests a new exercise program for people with non-traumatic shoulder instability (looseness without injury). It focuses on improving how well your rotator cuff muscles control shoulder rotation.
Gothenburg, MölndalAges 16–35 - NCT05774262Recruiting
Pacemaker or nerve-targeting treatment for certain heart rhythm blocks
This study compares two treatments for specific “AV block” heart rhythm problems: a pacemaker versus a procedure called cardioneuroablation. The goal is to see which approach works better for preventing symptoms like fainting or slow heart rates.
Dąbrowa GórniczaAges 18–75 - NCT06322654Recruiting
Comparing two types of robotic rehab for spinal muscular atrophy
This study compares two robot-assisted rehabilitation programs to see which one helps children and young adults with spinal muscular atrophy (SMA) improve their movement and function better. You may join if you have SMA (types 1-4), are up to 21 years old, and are already receiving medication for SMA.
PoznanAges Up to 21 years - NCT06324682Recruiting
Comparing heart pacemaker types for better treatment
This trial looks at different ways to pace the heart (like left, right, or both sides) to see which works best for people who need a pacemaker. If you have a heart condition requiring a pacemaker, this study may help find the safest and most effective option for you.
Ferrara, FEAges 18 years+ - NCT06335836Recruiting
Social connections and brain health in memory decline
This study looks at how being socially isolated or socially active affects memory and brain health in people who feel their thinking is getting worse. You may join if you notice a slow decline in memory or thinking, but otherwise have normal test results.
Nanjing, China, JiangsuAges 45–85 - NCT04151693Recruiting
Group therapy for chronic fatigue syndrome
This trial tests a health-psychology–based rehabilitation program delivered in a group setting for people with chronic fatigue syndrome (ME/CFS). It may help by teaching strategies to cope with symptoms and improving daily functioning through structured group support.
LahtiAges 18–65 - NCT05638503Recruiting
Study of heart changes in people with hypertension
This study looks at new ways to measure heart structure and heart pumping function in people with high blood pressure. The results may help doctors better understand heart changes over time and improve care.
Jinan, ShandongAges 30–75 - NCT06332742Recruiting
Herbal formula for low egg reserve in women ages 25–45
This trial tests a Chinese herbal formula called Qingxin Zishen Decoction to see if it can improve egg health and hormone levels in women with low ovarian reserve. It may be an option if you are between 25 and 45 and have not had surgery or hormone treatments recently.
Nanjing, JiangsuAges 25–45 - NCT06353620Recruiting
Brain connections study for certain epilepsies and genetic syndromes
This study uses MRI and a special EEG to understand brain connections in people with specific types of epilepsy or genetic conditions like Angelman syndrome and Dup15q. It may help find better ways to treat these conditions.
Conegliano, TrevisoAges 6–75 - NCT05468255Recruiting
Study how stopping exercise affects blood sugar and blood vessels
This study looks at what happens to blood sugar levels and blood vessel health when active adults stop exercising. It may help doctors understand how quickly these changes can happen and who may be most affected.
Norfolk, VirginiaAges Any age - NCT05747404Recruiting
3D heart ultrasound study for certain right-heart problems
This study uses a special 3D heart ultrasound to measure how well the tricuspid valve and right side of the heart are working. It may help improve how these conditions are evaluated and followed over time.
MilanAges 18 years+ - NCT05480826Recruiting
Family genetic study for mood, thinking, and autism conditions
This study looks at genetic changes found in people with conditions like bipolar disorder, schizophrenia, depression, or autism, and compares how those genetic differences may function. It may help researchers understand the causes of these conditions using information from patients and their relatives.
CréteilAges 18 years+ - NCT05621278Recruiting
School study of mental and physical well-being from kids to adults
This study follows students from middle school through high school and asks their parents and teachers questions about mental well-being and physical (body-related) health. It may help researchers understand what supports healthy development over time.
Beijing, Beijing MunicipalityAges 9–65 - NCT05558111Recruiting
Brain and bladder study after sigmoid bladder surgery
This study uses an MRI scan to look at how the brain controls bladder function after you’ve had a sigmoid “neobladder” surgery. You may be able to take part if you’re well enough for MRI and don’t have certain brain, mental health, or urinary conditions.
Guangzhou, GuangdongAges 18 years+ - NCT04754659Recruiting
Checking kidney function after EVAR stent graft for aneurysm
This study looks at how a stent graft treatment for an abdominal aortic aneurysm affects kidney function over time. It may help doctors choose the safest approach for people whose aneurysm is treated with a procedure called EVAR.
Gothenburg, VastraGotalandAges 18–90 - NCT06401057Recruiting
Long-term brain function tracking for brain lesions
This study creates a registry to track brain function over time in people with brain lesions. It aims to better understand how the brain works and may help improve future care.
HeidelbergAges 18 years+ - NCT03914378Recruiting
Study how radiation and cisplatin affect hearing in head and neck cancer
This study looks at how radiotherapy, and possibly cisplatin chemotherapy, affect hearing in people treated for head and neck cancer. It may help doctors better predict hearing side effects and plan hearing monitoring or prevention.
ManchesterAges 18 years+ - NCT06399939Recruiting
Biphasic sleep in 9-month-old infants
This study looks at how infants sleep in two different patterns (biphasic sleep) and how that relates to their development. If your child is 9 months old and healthy, researchers will track their sleep and development over the next 6 months.
Amherst, MassachusettsAges 9 months–1.3 years - NCT06404164Recruiting
3D Lung Map to Guide Small Nodule Surgery
This trial tests a new way to guide lung surgery by using a 3D map of the lung's natural zones (watersheds) to find the best spot to remove a small lung nodule. It aims to help doctors remove just the right amount of lung tissue while preserving as much healthy lung as possible.
Guangzhou, GuangdongAges Any age - NCT06345625Recruiting
Balance and walking with head movement in older adults
This study looks at how older adults keep their balance and walk when their head is moving. You may be asked to stand or walk while your head gently moves, so researchers can understand how your body reacts.
AntwerpAges 65–100 - NCT06068114Recruiting
Stomach function study in people with diabetes
This study looks at how diabetes affects stomach function by measuring stomach activity with special tests. It may help doctors better understand and treat stomach problems in people with diabetes.
OstravaAges 18–70
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Common questions
- Are there clinical trials for functionality?
- Yes. Clin2 currently lists 2,474 recruiting functionality studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a functionality trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a functionality trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.