Clinical trials
Functionality clinical trials
Below are recruiting functionality clinical trials, each written for real people, not researchers. We’re tracking 2,577 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05427136Recruiting
Study early lung problems after childhood cancer treatment
This study looks for early lung (breathing) problems in children after certain cancer treatments, using lung tests and sometimes MRI scans. It may help doctors spot breathing complications earlier and guide better care.
BaselAges 4–22 - NCT05443633Recruiting
Brain and speech training for people with aphasia
This study looks at ways to improve language (speaking and understanding) for people with aphasia caused by stroke or dementia, using MRI to study brain function. It may help by testing language-focused approaches and how brain activity changes during treatment.
Tucson, ArizonaAges 21–80 - NCT05445180Recruiting
Brain scan study of thinking in cannabis users with psychosis
This study uses brain imaging to understand how thinking works in people who use cannabis, comparing those with psychosis to people without psychosis. It may help researchers learn what brain patterns relate to thinking difficulties and how cannabis use fits in.
Montreal, QuebecAges 16–80 - NCT05445960Recruiting
Tourniquet use during ankle surgery and recovery outcomes
This study looks at whether using a tourniquet during ankle fracture surgery affects healing, leg movement, and patient-reported recovery. It may help doctors choose the safest, most comfortable approach for surgery.
Portland, OregonAges 18–89 - NCT05459090Recruiting
Study of how brain “brakes” work in drug-resistant temporal epilepsy
This study looks at how the brain’s natural “braking” system works in people with drug-resistant temporal lobe epilepsy. It may help researchers better understand the condition in order to improve future treatments.
Pozzilli, IserniaAges Any age - NCT05459116Recruiting
Record breathing effort to protect lungs during ventilation
This trial studies a way to measure how hard a patient is breathing and how the lungs and diaphragm are working while someone is on a breathing machine. The goal is to help the team use a “lung- and diaphragm-protective” ventilation strategy and see if it improves care.
Edegem, AntwerpAges 4 weeks+ - NCT05467215RecruitingEarly Phase 1
Brief oxygen breathing trial after spinal cord injury
This early-phase study tests whether a short period of breathing extra oxygen (hyperoxia) soon after lying in one position can improve physical function in people with long-term spinal cord injury. If you qualify, the goal is to see whether this treatment can help your body work better after chronic injury.
Edmonton, AlbertaAges 18–65 - NCT05468255Recruiting
Study how stopping exercise affects blood sugar and blood vessels
This study looks at what happens to blood sugar levels and blood vessel health when active adults stop exercising. It may help doctors understand how quickly these changes can happen and who may be most affected.
Norfolk, VirginiaAges Any age - NCT05473520RecruitingPhase 3
Doxycycline add-on therapy for lung improvement in tuberculosis
This Phase 3 trial tests whether adding doxycycline to standard TB medicine can improve lung function and reduce lung tissue damage. It aims to see if patients recover better by targeting the lung response to TB.
Kota Kinabalu, SabahAges 21 years+ - NCT05480826Recruiting
Family genetic study for mood, thinking, and autism conditions
This study looks at genetic changes found in people with conditions like bipolar disorder, schizophrenia, depression, or autism, and compares how those genetic differences may function. It may help researchers understand the causes of these conditions using information from patients and their relatives.
CréteilAges 18 years+ - NCT05487534Recruiting
How sugar swings may affect brain and eating in type 1 diabetes
This study looks at whether changes in blood sugar (“sugar swings”) affect brain functioning and eating behaviors in adults with type 1 diabetes. You would likely track your blood sugar and complete computer-based tasks or questionnaires to help researchers understand these links.
MontrealAges 18–65 - NCT05489042Recruiting
Brain scan and rTMS study for suicidal thoughts in opioid users
This study looks at brain connectivity using an MRI scan and then treats some people with rTMS (a non-surgical brain stimulation). It’s designed for adults who use opioids and currently have active suicidal thoughts, to better understand and help those symptoms.
Houston, TexasAges 18–64 - NCT05490745Recruiting
Parent-focused therapy to improve positive parenting in young children
This study tests a parenting-focused psychological program designed to support how parents understand and respond to their child’s feelings, especially after stressful events. It may help families improve parenting and child mental well-being for children ages 3–6 who are showing emotional or behavior concerns.
Braga, Braga DistrictAges 3–6 - NCT05493241Recruiting
Behavior therapy to help older veterans stay independent
This study tests a behavior-change program (called Behavioral Activation) to help older veterans keep their independence and daily functioning. It may help if you’re at risk of getting weaker or less able to do everyday activities.
Bedford, MassachusettsAges 65 years+ - NCT05498675Recruiting
Sacubitril/valsartan study for high blood pressure by body size
This study tests how sacubitril/valsartan may affect heart function in people with high blood pressure, and whether results differ by body size (BMI). You may benefit by getting closer heart monitoring, though it depends on whether you fit the safety and medical criteria.
Beijing, Beijing MunicipalityAges 18–70 - NCT05499091Recruiting
Study rare disease genetics using family and health data
This study tries to find genetic causes for rare diseases that are not yet understood. It uses a national rare-disease data bank and collects consent from patients and sometimes close family members.
AngersAges Any age - NCT05518617Recruiting
Imaging study for inherited Parkinson’s using PET, SPECT, and spinal fluid
This trial tests how well special brain scans (PET/SPECT) and spinal fluid tests can show changes in people with inherited (genetic) Parkinson’s. It may help researchers understand what’s happening in the brain and improve how these conditions are measured.
Exeter, DevonAges 25–80 - NCT05524610Recruiting
Screening plan for sexual health in young cancer survivors
This study tests a new way to screen for sexual problems in teens and young adults (ages 15–24) who have had childhood cancer. The goal is to better spot issues and improve care during survivorship.
Aurora, ColoradoAges 15–24 - NCT05525598Recruiting
Online therapy for severe body–mind symptom disorders
This trial tests an internet-based treatment program for people with moderate-to-severe functional somatic disorders (long-lasting physical symptoms linked to how the body and brain interact). It may help reduce symptoms and improve day-to-day functioning by offering structured support online.
Aarhus C, DenmarkAges 18–60 - NCT05525507RecruitingPhase 1
Test early immune-tolerance treatment for matched kidney transplant patients
This Phase 1 study tests a treatment plan given after a kidney transplant to help the immune system stay calm and reduce the risk of rejection. Participants must have a well-functioning kidney transplant from a closely matched living donor and meet health and safety requirements.
Los Angeles, CaliforniaAges 18 years+ - NCT05530681Recruiting
Ultrasound and pelvic floor health one year after vaginal birth
This study checks how pelvic floor function and ultrasound (picture) findings relate to each other about one year after childbirth. You may help researchers understand which physical changes after vaginal birth matter most and how to monitor them.
LeuvenAges 18–45 - NCT05539781Recruiting
Blood flow and brain function monitoring after carotid procedure
This trial studies how blood flow and brain function change after a carotid artery revascularization procedure (opening a narrowed carotid artery). It may help doctors understand what to expect after treatment, especially in people with significant artery narrowing.
Beijing, Beijing MunicipalityAges 18–85 - NCT05544344Recruiting
Program to improve health and daily functioning in adults
This trial studies a supportive “re-start” program to help adults with serious mental health conditions improve health and daily functioning. If you can join online sessions and meet the other requirements, you may be able to participate and see whether this program helps.
Chicago, IllinoisAges 18 years+ - NCT05553093RecruitingPhase 4
Tirzepatide vs insulin for diabetes and brain effects
This study tests how tirzepatide and insulin glargine affect blood sugar, fat metabolism, and brain function in adults with type 2 diabetes. It may help researchers learn which treatment changes diabetes-related body and brain processes.
Nanjing, JiangsuAges 18–75
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Common questions
- Are there clinical trials for functionality?
- Yes. Clin2 currently lists 2,577 recruiting functionality studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a functionality trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a functionality trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.