Clinical trials
Functionality clinical trials
Below are recruiting functionality clinical trials, each written for real people, not researchers. We’re tracking 2,577 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05558111Recruiting
Brain and bladder study after sigmoid bladder surgery
This study uses an MRI scan to look at how the brain controls bladder function after you’ve had a sigmoid “neobladder” surgery. You may be able to take part if you’re well enough for MRI and don’t have certain brain, mental health, or urinary conditions.
Guangzhou, GuangdongAges 18 years+ - NCT05558709Recruiting
Test for thinking and behavior skills in neurodegenerative disease
This trial checks a new kind of paper-and-pen (or computer-based) test to better measure thinking and social/behavior skills in people with certain brain diseases. It may help researchers improve how these skills are tracked and understood over time.
ParisAges 18–90 - NCT05561361Recruiting
Test treatment for primary aldosteronism and blood vessel function
This trial studies whether a specific treatment (related to spironolactone/aldosterone support) can improve how well your blood vessels work in people with primary aldosteronism. It may help reduce blood pressure risk by improving blood vessel health.
NanchangAges 18–75 - NCT05563805Recruiting
Virtual reality adventure training for movement and fitness
This study uses a virtual reality “adventure” game that gets you moving to train exercise skills and coordination. It’s designed for U.S. military veterans who can walk on their own and don’t have certain vision, balance, or medical limits.
Arlington, TexasAges 18–45 - NCT05565443Recruiting
Ultrasound plus GCase treatment for Parkinson’s symptoms
This trial studies whether MR-guided focused ultrasound combined with an enzyme treatment called GCase can improve Parkinson’s disease. It includes people with specific Parkinson’s diagnosis and scan findings, and it may help those with certain genetic or imaging markers.
Toronto, OntarioAges 35–80 - NCT05566483Recruiting
Study long COVID physiology and cardiopulmonary rehab effects
This study looks at how long COVID affects the body and whether cardiopulmonary rehabilitation improves quality of life and physical function. It may help participants better understand their symptoms and see if a structured rehab program improves daily abilities.
Aurora, ColoradoAges 18 years+ - NCT05570929Recruiting
Study of kidney changes before and around donation
This study follows people who are planning kidney donation or a kidney transplant to better understand how kidney function changes over time. It may help researchers predict risk and improve care by studying health markers in detail.
BerlinAges 18–75 - NCT05573828Recruiting
Using dye imaging to protect parathyroid glands during thyroid surgery
This trial studies whether a special “dye” imaging test during total thyroid surgery can help preserve your parathyroid gland function, which is important for calcium balance. It may reduce the risk of low calcium after surgery.
L'Hospitalet de Llobregat, BarcelonaAges 18–100 - NCT05574244Recruiting
Partial vs complete prostate surgery to preserve ejaculation
This trial compares two surgical approaches for men with benign prostate enlargement (BPH): one that aims to preserve ejaculation and one that removes more tissue. It looks at how well you recover urinary function and sexual outcomes after surgery.
Aix-en-ProvenceAges 40 years+ - NCT05575882Recruiting
Skin cream trial to prevent relapses in very dry eczema skin
This trial tests whether a cosmetic cream can reduce eczema flare-ups and is comfortable/safe to use on very dry, irritated, eczema-prone skin. It’s mainly for children who have had recent flare-ups and moderate eczema severity.
Ciudad Autónoma de Buenos Aire, Ciudad Autónoma de Buenos AireAges 6 months–15 years - NCT05576090Recruiting
Study tests sleep skills in UCLA students with insomnia symptoms
This study looks at whether sleep techniques can improve sleep problems. It’s designed for UCLA students living on campus who report meaningful insomnia symptoms, and it may help you learn practical ways to sleep better.
Los Angeles, CaliforniaAges 18–22 - NCT05577247Recruiting
Study of new thinking skills in hard-to-treat depression
This trial looks at how people with treatment-resistant major depression respond when starting a new depression medicine that affects glutamate signaling. It also involves brain scans and thinking/learning tasks, aiming to understand what helps people improve when standard treatments haven’t worked.
ParisAges 18–70 - NCT05577598Recruiting
Brain scan study of deep brain stimulation in OCD
This trial uses a special PET scan to see how brain sugar use changes during deep brain stimulation for obsessive-compulsive disorder (OCD). It may help researchers understand what brain activity patterns relate to treatment response.
Vienna, State of ViennaAges 18–75 - NCT05581147Recruiting
Thyroid health in Klinefelter syndrome
This study looks at how the thyroid gland works and how it looks on ultrasound in people with classic (non-mosaic) 47,XXY Klinefelter syndrome. It may help doctors understand thyroid-related problems in this condition by comparing test results, symptoms, and imaging.
RomaAges 1–80 - NCT05584722Recruiting
Study risk and resilience in pulmonary arterial hypertension
This study looks at how people with pulmonary arterial hypertension (PAH) and certain genetic risks cope and how their bodies respond over time. It may help researchers understand factors linked to better or worse outcomes, and how different people manage the condition.
Nashville, TennesseeAges 15–80 - NCT05586360RecruitingPhase 2
Testing how a statin may change immune markers in prostate cancer
This Phase 2 study tests whether taking simvastatin can change “immune regulation” markers in men with intermediate- to high-risk localized prostate cancer. It also looks at whether this could help lower the risk of cancer coming back after planned prostate surgery.
Atlanta, GeorgiaAges 18 years+ - NCT05593055RecruitingPhase 4
Test a heart and blood-pressure therapy in people with hypertension
This study looks at how mineralocorticoid-related hormone signaling affects small heart blood vessels and how efficiently the heart works in people with high blood pressure. It may help doctors understand which treatments could improve heart function in hypertension.
Boston, MassachusettsAges 18–75 - NCT05604716Recruiting
Surgery Patients: Digestive and Social Function Follow-Up Study
This study checks how your digestion and daily social functioning may change after surgery. It looks at results from completed questionnaires filled out after your diagnosis to understand what issues patients face.
Beijing, Beijing MunicipalityAges Any age - NCT05619068Recruiting
Study tracking outcomes in Moyamoya disease
This study looks at how Moyamoya disease changes over time and what predicts outcomes. It uses approved brain imaging and, likely, thinking/memory tests to understand prognosis.
Beijing, Beijing MunicipalityAges 10–60 - NCT05624125Recruiting
Beetroot juice study for circulation problems in leg arteries
This trial tests whether drinking beetroot juice can improve how well people with peripheral artery disease (PAD) can function and walk. It’s looking at circulation-related measurements in the legs and how you do on walking tests.
Chicago, IllinoisAges 50 years+ - NCT05626816Recruiting
Genital nerve stimulation to improve bowel control after spinal injury
This trial studies whether stimulating nerves near the genitals (a gentle electrical stimulation approach) can improve bowel function in people with spinal cord injury. It may help bowel control when bowel dysfunction is caused by nerve injury.
Cleveland, OhioAges 18 years+ - NCT05633706Recruiting
Testing a capsule to study gut bacteria in the small intestine
This study tests the SIMBA capsule to learn how gut bacteria (dysbiosis) relate to digestive conditions. It may help researchers better understand these conditions and how the capsule can be used safely.
Calgary, AlbertaAges 18–80 - NCT05638503Recruiting
Study of heart changes in people with hypertension
This study looks at new ways to measure heart structure and heart pumping function in people with high blood pressure. The results may help doctors better understand heart changes over time and improve care.
Jinan, ShandongAges 30–75 - NCT05638191Recruiting
Nerve transfer surgery for arm grasp after neck spinal cord injury
This study looks at whether nerve transfer surgery can help restore hand grasp function after a neck (cervical) spinal cord injury. You may be eligible if your injury is recent and you meet specific strength patterns and can commit to rehabilitation after surgery.
Vancouver, British ColumbiaAges 18–70
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Common questions
- Are there clinical trials for functionality?
- Yes. Clin2 currently lists 2,577 recruiting functionality studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a functionality trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a functionality trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.