Clinical trials
Functionality clinical trials
Below are recruiting functionality clinical trials, each written for real people, not researchers. We’re tracking 2,474 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06753812Enrolling by invitation
Lower limb therapy for children with unilateral cerebral palsy
This trial tests a therapy called constraint-induced movement therapy (CIMT) for the legs in children with unilateral cerebral palsy. It aims to improve leg function by encouraging use of the affected leg through structured exercises and activities.
BoluAges 5–15 - NCT06751537Recruiting
Testing a wearable device for COPD severity
This trial tests a wearable device (WearME) that tracks your breathing and activity to see how well it can measure COPD severity. It may help you and your doctor better understand your lung function at home.
Baltimore, MarylandAges 21–100 - NCT06747689Recruiting
Sleep quality and self-care in heart failure
This study looks at how sleep quality affects the ability of people with heart failure to manage their own health. It aims to find if better sleep leads to better self-care.
IzmirAges 18 years+ - NCT06738394Recruiting
Exercise study for older adults with kidney disease
This study tests whether a supervised exercise program can help older adults with chronic kidney disease improve their physical function and stay active. You have to be able to do exercise and not be on dialysis.
Winston-Salem, North CarolinaAges 65–100 - NCT06747000Recruiting
Study of fats in blood and platelets
This study looks at how fats (lipids) in your blood affect blood cells called platelets, which help with clotting. It includes both healthy people and those with high cholesterol or other fat issues.
East Providence, Rhode IslandAges 18–69 - NCT06727773RecruitingPhase 2
Memantine and exercise to protect thinking during chemo for breast cancer
This study tests whether a medicine called memantine combined with a structured exercise program can help protect your thinking and memory during chemotherapy for breast cancer. It may also help understand how these treatments work in the body.
Chapel Hill, North CarolinaAges 18 years+ - NCT06729437Recruiting
Transcranial brain stimulation for patellar tendon pain
This trial tests whether a gentle brain stimulation technique called transcranial direct current stimulation (tDCS) can improve knee function and reduce pain in people with long-term patellar tendinopathy (jumper's knee). It may help by calming pain signals in the brain.
Valencia, ValenciaAges 18–50 - NCT06737770Recruiting
Bone-anchored leg implant study
This study tests a bone-anchored implant (directly attached to the thighbone) for people with a single leg amputation above the knee. It aims to see if this implant helps with pain, movement, and skin issues caused by a traditional socket prosthetic.
BolognaAges 18–65 - NCT06727500Recruiting
Exercise training for kids with obesity
This trial tests whether two types of exercise training (high-intensity interval training or a mix of HIIT and jumping exercises) improve muscle and tendon health in children and teenagers with obesity. It looks at how results differ based on whether kids are before or after their growth spurt.
SantiagoAges 7–17 - NCT05964712Recruiting
Therapies for acromegaly and effects on body movement
This study looks at how treatments for acromegaly affect how you function and move, especially in your hands, feet, and overall body structure. You may be asked to do assessments to understand changes over time and whether certain groups respond differently.
MilanAges 18–90 - NCT06265636Recruiting
Nerve stimulation for jaw pain and function in TMD
This trial tests whether gentle electrical stimulation of a nerve in your jaw can reduce pain and improve chewing, talking, and mouth opening for people with temporomandibular joint disorder (TMD).
Alcorcón, MadridAges 18–65 - NCT06723717RecruitingPhase 2
Daily dornase alfa after aneurysm bleed for better recovery
This trial tests whether giving dornase alfa daily for up to 14 days after a subarachnoid hemorrhage (a type of bleeding around the brain from a burst aneurysm) helps people be more independent 6 months later. It is for people whose bleeding started less than 48 hours ago and whose aneurysm has already been treated.
Grenoble, GrenobleAges 18 years+ - NCT06724289RecruitingEarly Phase 1
Psilocybin for prolonged grief
This trial tests if a single dose of psilocybin (a psychedelic drug) can help people with prolonged grief disorder. You'll receive counseling and be observed in a safe setting.
Charlottesville, VirginiaAges 18–65 - NCT06725550Recruiting
Acupuncture for pain in sickle cell disease
This trial tests whether adding acupuncture to standard pain treatments can help manage pain in people with sickle cell disease. It involves brain scans, questionnaires, and acupuncture sessions to see if this approach reduces pain and improves quality of life.
Cincinnati, OhioAges 14–80 - NCT06719739Recruiting
Special lens implant for cataract patients with epiretinal membrane
This study tests a special intraocular lens (IOL) implanted during cataract surgery in people who also have epiretinal membrane (ERM), a thin layer of scar-like tissue on the retina. The goal is to see if this lens works well and safely for their eyes.
Shanghai, Shanghai MunicipalityAges 20–90 - NCT06717711RecruitingPhase 3
Shockwave therapy for penis recovery after prostate cancer surgery
This trial tests if low-intensity shockwaves can help men regain erectile function after robot-assisted prostate surgery. If you had nerve-sparing surgery and have good erections before treatment, this may help you recover faster.
Rome, RMAges 18–75 - NCT06724393Enrolling by invitation
Blood Flow Restriction Exercise for Older Adults
This study tests whether low-intensity exercise with blood flow restriction (using special cuffs on your arms or legs) can improve strength and daily function in older adults. You join online classes from home and go to the campus three times for check-ups.
Montreal, QuebecAges 60 years+ - NCT06724653Recruiting
Reducing Heart Failure Meds After Heart Recovery Study
This trial tests whether it is safe to slowly reduce some heart failure medications for people whose heart function has improved to normal. It is for patients who once had a weak heart pump but now have recovered strength and are stable on multiple medicines.
Jeonju, Jeollabuk-doAges 18 years+ - NCT05800470Recruiting
Brain-training with light sensors to improve walking in Parkinson’s
This trial tests a “neurofeedback” training program using a special light-sensing cap (fNIRS) to help improve balance and walking in people with Parkinson’s disease. You may also do guided walking practice mentally (imagery training), and your ability to walk and balance will be measured.
Taipei, None SelectedAges 40–85 - NCT06705816Recruiting
Cognitive function in Rett syndrome during trofinetide treatment
This study looks at how trofinetide (a medicine for Rett syndrome) affects thinking and memory in people with Rett syndrome. It will follow participants who are starting this treatment through a specific clinic.
Minneapolis, MinnesotaAges 18–99 - NCT06709027Enrolling by invitation
Mobile health program for depression in older adults
This study is testing a smartphone-based health program designed for older adults with depression. The program aims to help you manage your mood and track changes in thinking and memory using a mobile app.
Fuzhou, FujianAges 60 years+ - NCT06706882Enrolling by invitation
Thinking and memory in women who have experienced partner violence
This study looks at how thinking skills like planning and memory are affected in women who have survived intimate partner violence. It may help explain how these experiences affect daily life and mental health.
Granada, GranadaAges 18–50 - NCT06710418Recruiting
Comparing two red blood cell transfusion thresholds for people with high-grade myeloid neoplasms, AML or B-ALL
This study compares two different strategies for when to give red blood cell transfusions to people receiving intensive chemotherapy or stem cell transplant for high-grade myeloid neoplasms, AML or B-ALL. The goal is to see which approach better improves quality of life and daily function.
Seattle, WashingtonAges 18 years+ - NCT06705790Recruiting
Pelvic floor training for bladder, bowel, and sexual health after spinal cord injury
This study tests whether pelvic floor muscle exercises can improve bladder, bowel, and sexual function in people with a spinal cord injury. If you have ongoing symptoms in these areas and a stable health routine, this trial may help you learn ways to strengthen those muscles.
Vancouver, British ColumbiaAges 19 years+
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Common questions
- Are there clinical trials for functionality?
- Yes. Clin2 currently lists 2,474 recruiting functionality studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a functionality trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a functionality trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.