Clinical trials
Functionality clinical trials
Below are recruiting functionality clinical trials, each written for real people, not researchers. We’re tracking 2,474 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05558709Recruiting
Test for thinking and behavior skills in neurodegenerative disease
This trial checks a new kind of paper-and-pen (or computer-based) test to better measure thinking and social/behavior skills in people with certain brain diseases. It may help researchers improve how these skills are tracked and understood over time.
ParisAges 18–90 - NCT05561361Recruiting
Test treatment for primary aldosteronism and blood vessel function
This trial studies whether a specific treatment (related to spironolactone/aldosterone support) can improve how well your blood vessels work in people with primary aldosteronism. It may help reduce blood pressure risk by improving blood vessel health.
NanchangAges 18–75 - NCT05565443Recruiting
Ultrasound plus GCase treatment for Parkinson’s symptoms
This trial studies whether MR-guided focused ultrasound combined with an enzyme treatment called GCase can improve Parkinson’s disease. It includes people with specific Parkinson’s diagnosis and scan findings, and it may help those with certain genetic or imaging markers.
Toronto, OntarioAges 35–80 - NCT04171323Recruiting
Active mind training to improve thinking and delay dementia
This study tests an “active mind” computer-based program to help improve thinking skills and possibly slow the process toward dementia. You may be randomly assigned to different program options to see which approach works best for your goals.
San Francisco, CaliforniaAges 55–89 - NCT05028712Recruiting
Multi-sensory rehab program for people with ultra low vision
This trial tests a rehabilitation program using multiple senses to help people with very low vision function more independently. It may help you learn new skills for daily life by using vision plus other senses.
New York, New YorkAges 12–99 - NCT04713722Recruiting
Study of early stress and depression using brain imaging
This study looks at how early life stress may be linked to depression, using brain scans. You’ll be asked about your history and asked to do brain imaging to help researchers understand these brain and mood changes.
Belmont, MassachusettsAges 20–32 - NCT05527548RecruitingPhase 4
Alendronate for knee recovery after ACL surgery
This trial tests whether alendronate, a drug commonly used for bone health, can improve knee function and recovery after ACL surgery. It is for people having their first ACL repair.
ShatinAges 14 years+ - NCT05524610Recruiting
Screening plan for sexual health in young cancer survivors
This study tests a new way to screen for sexual problems in teens and young adults (ages 15–24) who have had childhood cancer. The goal is to better spot issues and improve care during survivorship.
Aurora, ColoradoAges 15–24 - NCT05508035RecruitingPhase 3
Testing sacubitril/valsartan vs ramipril for heart failure
This trial compares two blood-pressure and heart-failure medicines: sacubitril/valsartan versus ramipril, to see which improves heart pumping and heart structure over time. It’s aimed at people with ischemic (blocked-artery) heart failure with mid-range ejection fraction and ongoing symptoms.
Krakow, Lesser Poland VoivodeshipAges 18 years+ - NCT05499091Recruiting
Study rare disease genetics using family and health data
This study tries to find genetic causes for rare diseases that are not yet understood. It uses a national rare-disease data bank and collects consent from patients and sometimes close family members.
AngersAges Any age - NCT05493241Recruiting
Behavior therapy to help older veterans stay independent
This study tests a behavior-change program (called Behavioral Activation) to help older veterans keep their independence and daily functioning. It may help if you’re at risk of getting weaker or less able to do everyday activities.
Bedford, MassachusettsAges 65 years+ - NCT05500066Enrolling by invitation
Shoulder implant study for people needing shoulder replacement
This trial studies a specific shoulder replacement implant system. It may help people with damaged shoulder joints by testing how well the implant works and how it affects recovery and function.
Denver, ColoradoAges 18 years+ - NCT05467215RecruitingEarly Phase 1
Brief oxygen breathing trial after spinal cord injury
This early-phase study tests whether a short period of breathing extra oxygen (hyperoxia) soon after lying in one position can improve physical function in people with long-term spinal cord injury. If you qualify, the goal is to see whether this treatment can help your body work better after chronic injury.
Edmonton, AlbertaAges 18–65 - NCT05473520RecruitingPhase 3
Doxycycline add-on therapy for lung improvement in tuberculosis
This Phase 3 trial tests whether adding doxycycline to standard TB medicine can improve lung function and reduce lung tissue damage. It aims to see if patients recover better by targeting the lung response to TB.
Kota Kinabalu, SabahAges 21 years+ - NCT05501028Enrolling by invitation
Audio-recorded gut symptom interview to help diagnose FGIDs
This trial uses natural-language conversations (spoken interactions) to improve how clinicians evaluate and diagnose functional gastrointestinal disorders, a group of conditions that affect the gut. If you are scheduled for a GI clinic visit or a diagnostic endoscopy, your recorded responses may help build better evaluation tools.
Boston, MassachusettsAges 18 years+ - NCT05498116RecruitingPhase 4
Montelukast to improve kidney and blood vessel function in type 1 diabetes
This trial tests whether montelukast, a medicine commonly used for allergies, can improve kidney health and blood vessel function in adults with long-term type 1 diabetes. You may join a treatment group and have kidney and circulation measurements taken over the study period.
Aurora, ColoradoAges 18–80 - NCT05436600Recruiting
Exercise program for people with narrowed neck arteries
This trial studies whether a supervised exercise program can improve mobility and balance in people who have narrowed carotid arteries in the neck but no stroke symptoms. If you fit the criteria, the goal is to see whether exercise helps your movement and safety without increasing risks.
Baltimore, MarylandAges 18–89 - NCT05427136Recruiting
Study early lung problems after childhood cancer treatment
This study looks for early lung (breathing) problems in children after certain cancer treatments, using lung tests and sometimes MRI scans. It may help doctors spot breathing complications earlier and guide better care.
BaselAges 4–22 - NCT05414357Recruiting
Sleep and thinking in breast cancer survivors
This study looks at how sleep problems affect memory, thinking, and quality of life in women who have had breast cancer surgery. If you are having trouble sleeping, joining could help you understand these effects better.
CaenAges 45–65 - NCT05435859Enrolling by invitation
Mapping the brain area for speech during surgery
This study uses tiny brain electrodes placed during surgery to better understand how a brain region helps with speech. The results may guide safer brain mapping during surgery for people with epilepsy or brain tumors.
San Francisco, CaliforniaAges 18–70 - NCT05445180Recruiting
Brain scan study of thinking in cannabis users with psychosis
This study uses brain imaging to understand how thinking works in people who use cannabis, comparing those with psychosis to people without psychosis. It may help researchers learn what brain patterns relate to thinking difficulties and how cannabis use fits in.
Montreal, QuebecAges 16–80 - NCT04550728RecruitingPhase 1/Phase 2
Robot training plus electrical stimulation after stroke
This trial tests a “hybrid” rehab program that combines robot-assisted walking practice with electrical stimulation to help movement after stroke. It may help people improve walking and leg function at home as they work with a caregiver.
Baltimore, MarylandAges 18–85 - NCT05400499Recruiting
Deep brain stimulation study in Parkinson’s visuomotor function
This trial studies how deep brain stimulation affects hand-eye (visuomotor) coordination in people with Parkinson’s. It may help researchers understand whether the stimulation settings change movement control for daily tasks.
Cleveland, OhioAges Any age - NCT05376254Recruiting
3D heart scan study during LVAD implantation
This study uses special 3D heart imaging to better measure right-heart function during LVAD surgery. It may help doctors understand how the right side of the heart responds when a mechanical pump is put in.
Edmonton, AlbertaAges 16 years+
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Common questions
- Are there clinical trials for functionality?
- Yes. Clin2 currently lists 2,474 recruiting functionality studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a functionality trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a functionality trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.