Clinical trials
Gastric Cancer Stage III clinical trials
Below are recruiting gastric cancer stage iii clinical trials, each written for real people, not researchers. We’re tracking 124 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03941561RecruitingPhase 3
Shorter versus longer chemotherapy for stage II stomach cancer
This trial compares two lengths of an oral chemotherapy medicine (9 months vs 1 year) after surgery for stage II stomach cancer. It aims to see which schedule works better and is easier to complete, while checking safety for people without major health problems.
AnqingAges 18–75 - NCT04595929Recruiting
Tested aerosol chemotherapy inside the abdomen for stomach cancer
This trial looks at a way to give chemotherapy into the abdomen (through a small tube during laparoscopy) for certain stomach cancers. It aims to see whether this approach improves cancer control and surgical outcomes for people whose tumors can potentially be removed.
Saint PetersburgAges 18–65 - NCT04483076RecruitingPhase 3
Chemo before stomach surgery with different cycles
This trial studies whether giving oxaliplatin plus S-1 (SOX) chemotherapy before stomach surgery works best when given for different cycle lengths. It may help shrink stage III gastric cancer before a standard D2 gastrectomy and improve outcomes.
Beijing, Beijing MunicipalityAges 18–70 - NCT04843215Recruiting
Surgery comparison for advanced stomach cancer after initial surgery
This trial studies whether removing all of the fatty lining (omentum) or only part of it during surgery leads to better outcomes in people with advanced stomach cancer. It also checks that participants can safely have the same stomach-cancer chemotherapy plan after surgery.
Tianjin, Tianjin MunicipalityAges 18–70 - NCT05537129Recruiting
Laparoscopic vs open stomach surgery for stomach cancer
This trial compares two ways surgeons remove the entire stomach (total gastrectomy): laparoscopic (small keyhole cuts) versus open surgery (one larger cut). It’s testing which approach is safer and works better for people with certain stages of stomach cancer.
Shanghai, Shanghai MunicipalityAges 20–80 - NCT05618821RecruitingPhase 2
Indocyanine green dye during stomach surgery for leftover cancer
This Phase 2 study tests whether using a special light-activated dye (indocyanine green) during laparoscopic stomach surgery can improve surgical outcomes for people with remnant (leftover) stomach cancer that has not spread to distant organs. It may help surgeons better find lymph nodes while operating.
Fuzhou, FujianAges 18–75 - NCT05723718Recruiting
Testing body-water measurements in people with stomach cancer
This trial uses a painless machine to measure your body composition (mainly fluid and muscle) using bioelectrical impedance. It’s looking at people with stage II–III stomach cancer who are receiving standard “multi-treatment” care, to see whether these measurements are useful during treatment.
LublinAges 18–100 - NCT06042998Recruiting
Robot vs. laparoscopic surgery for stomach cancer after chemo
This trial compares robotic and laparoscopic surgery for stomach cancer patients who have already received chemotherapy or targeted therapy. It aims to see which approach leads to better outcomes after neoadjuvant (pre-surgery) treatment.
Qingdao, ShandongAges 18–75 - NCT01935778RecruitingPhase 3
Extra chemo after stomach cancer surgery: compare two drug plans
This Phase 3 trial tests which combination of chemotherapy works better after surgery for stage IIIB/IV stomach or stomach–esophagus junction adenocarcinoma. Participants get randomized to one of two chemotherapy plans to see which helps people live longer and/or prevents cancer from coming back.
SeoulAges 20–75 - NCT05975749RecruitingPhase 2
Trastuzumab, serplulimab, and chemo after stomach cancer surgery
This Phase 2 study looks at whether adding serplulimab to trastuzumab and chemotherapy after surgery can lower the chance of stomach cancer coming back. It is for people with HER2-positive stage II–III stomach adenocarcinoma who have already had curative surgery with lymph node removal.
Shanghai, Shanghai MunicipalityAges 20–80 - NCT04660760RecruitingPhase 2
Comparing two treatments for advanced stomach cancer after first treatment
This study tests two different treatment options for advanced stomach or gastroesophageal junction cancer that has grown after earlier chemotherapy. One option combines a targeted therapy (ramucirumab) with a chemotherapy pill (trifluridine/tipiracil), and the other is a standard chemotherapy drug (paclitaxel). The goal is to see which approach works better for people whose cancer has progressed, with the hope of improving outcomes.
Birmingham, AlabamaAges 18 years+ - NCT06161207RecruitingPhase 3
Laparoscopic surgery for stomach cancer using 3D and dye
This trial tests a new way to remove stomach cancer using 3D-4K cameras and a special dye during laparoscopic (keyhole) surgery. It may help surgeons see the cancer better and remove it more precisely.
Fuzhou, FujianAges 18–75 - NCT07829081Recruiting
Watch-and-wait after immunotherapy for early-stage GI cancers
This study looks at whether some patients with early-stage stomach, colon, or rectal cancers that are mismatch repair-deficient (a genetic feature making them more likely to respond to immunotherapy) can safely avoid surgery and instead be monitored closely after treatment with immunotherapy. It aims to confirm if this watch-and-wait approach is as effective and helps patients avoid major operations.
BaselAges 18 years+ - NCT06313567RecruitingPhase 3
Metronomic capecitabine for stage III stomach cancer
This trial tests a low-dose, frequent regimen of the chemotherapy drug capecitabine (taken as a pill) to see if it can help prevent stage III stomach cancer from coming back after surgery. It's for people who have had their stomach cancer completely removed with a specific type of lymph node dissection.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07817147Recruiting
Microwave ablation treatment for advanced cancer
This study tests a procedure called microwave ablation (using heat to destroy cancer cells) for tumors that are hard to remove with surgery. It aims to see if the procedure is safe and effective when done through a scope in the stomach.
Gilbert, ArizonaAges 18 years+ - NCT07770100RecruitingPhase 2
Matching immunotherapy and targeted radiation for advanced cancer
This trial tests combining immunotherapy (a treatment that boosts your immune system to fight cancer) with a targeted type of radiation called SBRT, which precisely delivers high-dose radiation to multiple cancer spots. The main goal is to see if this combination helps control metastatic cancer (cancer that has spread) better than standard care.
Lexington, KentuckyAges 18–99 - NCT07619521RecruitingPhase 1/Phase 2
Combination drug therapy for advanced pancreatic cancer
This trial tests two targeted drugs, selumetinib and DS-8201a (trastuzumab deruxtecan), for advanced pancreatic cancer that has spread or cannot be removed. The combination may help people whose tumors have specific markers (KRAS mutation and HER2 positivity).
New Haven, ConnecticutAges 18 years+ - NCT07587229Recruiting
Predicting chemotherapy response in gastric cancer
This research study analyzes tumor tissue samples to understand why some patients respond better to chemotherapy after gastric cancer surgery. By studying how genes are processed in cancer cells, researchers hope to predict which patients will benefit most from treatment.
Duarte, CaliforniaAges 18 years+ - NCT07533825Enrolling by invitation
Minimally Invasive Surgery Staging for Advanced Stomach Cancer
This trial tests whether a minimally invasive camera-guided surgical procedure (laparoscopy) can better detect hidden cancer spread in patients with advanced stomach cancer. The goal is to help doctors plan the best treatment and improve outcomes.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT07517107RecruitingPhase 2
Blood tests to guide gastric cancer treatment decisions
This study uses special blood tests to detect cancer DNA and help doctors decide the best treatment plan for gastric cancer. The goal is to improve outcomes by personalizing therapy based on how your cancer responds.
ShanghaiAges 18 years+ - NCT06786169Recruiting
Stress and treatment results in stomach cancer
This study looks at how psychological stress affects treatment success and long-term outcomes in people with stomach cancer. It includes three different groups of patients at various stages of the disease.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06792162RecruitingPhase 2
Immunotherapy and targeted therapy trial for advanced gastric cancer
This trial tests a combination of two drugs: carilizumab (an immunotherapy) and apatinib (a targeted therapy) for patients with unresectable stage III or IV gastric cancer that has a specific DNA repair problem (dMMR). The goal is to see if this treatment can help shrink tumors and improve outcomes.
BeijingAges 18 years+ - NCT07441785Recruiting
Comparing stomach reconstruction types after upper stomach cancer surgery
This study compares different ways to rebuild the digestive tract after removing the upper part of the stomach for cancer. It aims to find which method works best for eating and quality of life.
MoscowAges 18 years+ - NCT07443943RecruitingPhase 2
Potato starch supplement for joint pain from hormone therapy
This trial studies whether a dietary supplement made from resistant potato starch can help reduce joint and muscle pain in people who are about to start aromatase inhibitor therapy for breast cancer or high risk. You take the supplement daily and report how you feel over 24 weeks.
Ann Arbor, MichiganAges Any age
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Common questions
- Are there clinical trials for gastric cancer stage iii?
- Yes. Clin2 currently lists 124 recruiting gastric cancer stage iii studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gastric cancer stage iii trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gastric cancer stage iii trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.