Clinical trials
Gastrointestinal clinical trials
Below are recruiting gastrointestinal clinical trials, each written for real people, not researchers. We’re tracking 482 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05606848Recruiting
Testing a special nutrition drink around surgery for gut cancer
This study tests whether a special medical nutrition (a drink/food meant for people who need medical nutrition) given around the time of surgery helps patients with gastrointestinal cancer recover better. It aims to see if this nutrition approach is safe and beneficial when cancer is being removed.
BeijingAges 18–75 - NCT05623722Recruiting
Nerve block to help organ function in severe gut sepsis
This trial studies whether an erector spinae plane nerve block (a pain-control injection near the spine) can improve organ health in adults with sepsis caused by acute gut injury. It’s meant for people sick enough to need ICU care for several days.
Guangzhou, GuangdongAges 18 years+ - NCT05651672RecruitingPhase 2
Pemigatinib for advanced gut cancers with FGFR gene changes
This Phase 2 trial tests pemigatinib, a targeted medicine, for advanced or metastatic gastrointestinal (GI) cancers that have specific FGFR1–3 gene changes. It’s for people whose cancer has grown despite prior standard treatment, and who may benefit if their tumor has the right genetic change.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT05694338Recruiting
Study frailty during major surgery for gut cancer
This trial studies how “frailty” affects people with gastrointestinal (gut) cancer who are about to have major surgery, sometimes after chemotherapy or other treatment beforehand. It may help doctors better prepare and support patients through surgery.
East Corning, New YorkAges 18 years+ - NCT05743426Recruiting
Tracking outcomes and side effects in GI and sarcoma cancers
This study follows adults with gastrointestinal cancer or sarcoma to better understand how patients do after treatment and what side effects happen. It may help researchers improve care for future patients by documenting real-world outcomes and toxicities.
Chapel Hill, North CarolinaAges 18 years+ - NCT05789485RecruitingPhase 2
Exercise program to reduce treatment side effects in GI cancer
This trial studies whether a structured exercise plan can lessen side effects from chemotherapy in people with colorectal or stomach/esophagus solid tumors. If you’re about to start chemotherapy, the study will check whether exercising helps you feel and function better during treatment.
Hartford, ConnecticutAges 18 years+ - NCT05844865Recruiting
GI cancer study using a lab tumor model from your surgery
This study uses a special lab model made from tumor tissue taken during a planned standard cancer surgery. It tests how well the lab model can represent your cancer, which may help researchers improve future treatments.
Orange, CaliforniaAges 18 years+ - NCT05880199Recruiting
Test Meal and Monitoring in Teens With GI Symptoms
This study studies how a standardized meal affects digestion using special monitoring in children and young adults with stomach or gut symptom problems (and compares them to healthy controls). It may help doctors understand what causes gut symptoms and guide better treatments.
San Diego, CaliforniaAges 8–25 - NCT05905887RecruitingPhase 2
Rivoceranib and paclitaxel for advanced gastrointestinal stromal tumor
This Phase 2 trial tests whether combining rivoceranib with paclitaxel can shrink or control advanced metastatic gastrointestinal stromal tumor (GIST) after standard medicines have stopped working. It may help people whose GIST has progressed despite prior treatments like imatinib, sunitinib, and regorafenib.
Seoul, SeoulAges 20 years+ - NCT05938309Recruiting
Safety study of laparoscopic surgery for large stomach GISTs
This study looks at how safe laparoscopic surgery is for stomach GISTs that are 5 cm or larger. If you’re eligible and choose to participate, your team will plan and perform surgery and track safety outcomes.
Fuzhou, FujianAges 18–75 - NCT05949268Recruiting
Video capsule test to find bleeding in the small intestine
This trial studies whether a swallowable camera capsule can detect bleeding in the small intestine when standard scopes (up the stomach and through the colon) haven’t found the cause. If your bleeding source is suspected but not seen on those tests, this could help identify where the bleeding is coming from.
Freiburg im BreisgauAges 18 years+ - NCT05951517Recruiting
Mycophenolate for stubborn stomach Purpura (HSP) in children
This trial looks at whether mycophenolate mofetil can help children ages 3–18 who have Henoch-Schönlein purpura affecting the gut that does not improve with steroid treatment. It may help reduce serious stomach symptoms like severe belly pain, bleeding, or bowel problems.
Guangzhou, GuangdongAges 3–18 - NCT06002425Recruiting
AI guidance for stomach and colorectal cancer treatment
This study uses a computer program (like ChatGPT) to help doctors recommend the best treatments for people with stomach or colorectal cancer. All your care must happen at one of the study hospitals.
Duarte, CaliforniaAges 18 years+ - NCT06031025Recruiting
Study of tummy problems in at-risk infants
This study looks at how common stomach and gut issues are in babies who were born early or had problems at birth, and how these issues change over time.
RomaAges 3 months–2 years - NCT06065371RecruitingPhase 1
Sacituzumab govitecan plus capecitabine for advanced GI cancers
This trial tests a combination of two drugs—sacituzumab govitecan (targeted therapy) and capecitabine (chemotherapy)—for people with advanced stomach, colon, or pancreatic cancer that has stopped responding to standard treatments.
Detroit, MichiganAges 18 years+ - NCT06072976Recruiting
How feeding affects gut health in babies with bowel conditions
This study looks at whether breast milk or formula helps babies with certain bowel problems heal faster and reach full feeds sooner. It compares how different milk affects the bacteria in a baby's gut.
Seattle, WashingtonAges birth–55 years - NCT06152757RecruitingEarly Phase 1
Cell therapy for advanced gastrointestinal cancers
This trial tests a new type of cell therapy (BGT007H cells) for people with advanced gastrointestinal cancers that have not responded to at least two standard treatments. The therapy uses your own immune cells that are modified to target and attack the cancer.
Zhengzhou, HenanAges 18 years+ - NCT06188585Recruiting
New blue dye vs standard treatment for upper GI bleeding
This study tests a new blue dye spray (UI-EWD) versus standard endoscopy treatment for people with active upper GI bleeding. The goal is to see if the dye helps doctors find and stop bleeding more effectively.
New Haven, ConnecticutAges 22 years+ - NCT06215222Recruiting
Studying gut bacteria in IBS and digestive issues
This study uses a tiny capsule to collect samples from your small intestine to learn about gut bacteria in people with IBS or other functional gut disorders. It could help researchers understand what causes digestive symptoms.
Redwood City, CaliforniaAges 18–70 - NCT06222645Recruiting
Comparing two dyes in gastrointestinal surgery
This trial compares two dyes used during stomach or intestine surgery to see which helps surgeons see the blood flow better. It may help decide which dye works best for safe reconnections.
Yantai, ShandongAges 18 years+ - NCT06263088Recruiting
Equity in GI Cancer Care Study
This trial is looking for Black patients newly diagnosed with any stage of gastrointestinal cancer to help improve cancer care and make sure research includes everyone. By joining, you help doctors learn how to better support patients like you.
Cleveland, OhioAges 18 years+ - NCT06420206Recruiting
Goals of care discussion in the ER for advanced cancer
This study is for people with advanced lung or GI cancer who come to the emergency room at MD Anderson. It’s testing a conversation to help you and your doctor discuss your goals and wishes for care.
Houston, TexasAges 18 years+ - NCT06445062RecruitingPhase 1/Phase 2
Study of new RAS inhibitors for GI solid tumors
This trial tests new drugs that target specific RAS mutations in advanced gastrointestinal cancers, like pancreatic or colorectal cancer. It aims to see if these drugs can shrink tumors or slow their growth.
Chandler, ArizonaAges 18 years+ - NCT06466096Recruiting
Thinking and memory after stomach/colon cancer surgery
This study looks at how older adults (65+) think and remember after surgery for gastrointestinal cancer. It compares those who have temporary confusion after surgery with those who don't, to understand long-term changes in brain function.
BeijingAges 65–100
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Common questions
- Are there clinical trials for gastrointestinal?
- Yes. Clin2 currently lists 482 recruiting gastrointestinal studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gastrointestinal trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gastrointestinal trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.