Clinical trials
General Population (no Specific Condition or Disease) clinical trials
Below are recruiting general population (no specific condition or disease) clinical trials, each written for real people, not researchers. We’re tracking 10,612 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06538649RecruitingEarly Phase 1
Testing statins for Crohn's disease before and after surgery
This study tests whether taking a statin (a cholesterol-lowering medicine) before and after surgery for Crohn's disease can help improve outcomes. It's for people with a specific type of Crohn's that causes narrowing in the small intestine and who are already scheduled for surgery.
Stanford, CaliforniaAges 18–80 - NCT06527768Recruiting
Helping with metabolic syndrome and kidney disease through lifestyle changes
This study tests a program that uses WeChat to help people with metabolic syndrome and chronic kidney disease make healthy lifestyle changes. They want to see if this support can improve health and slow down kidney problems.
Chengdu, SichuanAges 18 years+ - NCT06529913Recruiting
Metals, pollutants, and risk of allergies
This study looks at whether heavy metals, nanoparticles, and other pollutants in the environment increase the risk of allergic diseases like contact dermatitis. If you have a metal allergy or are a healthy adult, you may help researchers understand how these exposures affect your health.
BolognaAges 18 years+ - NCT06523270Recruiting
Advanced imaging biobank study
This study collects medical images (CT and MRI scans) and data from adults who are already having scans at the hospital. It creates a biobank to help researchers learn more about health and disease.
MilanAges 18 years+ - NCT06520397RecruitingPhase 4
Combination therapy vs. higher dose ustekinumab for Crohn's
This trial tests whether a combination of two drugs (upadacitinib and ustekinumab) works better than a higher dose of ustekinumab alone for people with active Crohn's disease that hasn't responded well to previous treatments.
Guangzhou, GuangdongAges 18–70 - NCT06525987Recruiting
Exercise coaching for brain health after small stroke
This study tests whether a home-based exercise program, guided by a coach over video calls, can help improve brain function and connectivity in people who have had a small stroke. The program is designed for people aged 60 and older with a history of lacunar stroke who are not very active but otherwise have minimal disability.
Avezzano, L'AquilaAges 60 years+ - NCT06518824Recruiting
Theta brain stimulation to boost thinking in Parkinson's
This study tests whether a special pattern of deep brain stimulation (called theta bursts) can improve thinking and memory in people with Parkinson's disease. It's for patients who already have a DBS device in their brain that is at least 3 months old.
Vancouver, British ColumbiaAges 18–80 - NCT06526195Recruiting
A study of CardioMEMS and HeartMate 3 for advanced heart failure
This trial tests if a combination of a tiny lung-artery pressure sensor (CardioMEMS) and a mechanical heart pump (HeartMate 3) is safe and effective for people with advanced heart failure. If you qualify, you'll either get the heart pump plus standard medical therapy, or continue with standard therapy alone and have your pressure monitored remotely.
Phoenix, ArizonaAges 18 years+ - NCT06514001RecruitingPhase 2
Testing a new drug for Alzheimer's disease with eye scans
This trial tests an investigational drug called AMDX-2011P for people with Alzheimer's disease. It looks at whether the drug affects the retina, which may be linked to brain changes in Alzheimer's.
Phoenix, ArizonaAges 18 years+ - NCT06518681Enrolling by invitation
Testing a new polymer heart valve for aortic disease
This trial tests a new type of artificial heart valve made of polymer (a special plastic-like material) for people with severe aortic valve disease. It aims to see if the valve is safe and works well, giving you an option for a replacement valve that might last longer.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06506942Recruiting
TRICURE device study for leaky heart valve
This study tests a new device to help people with severe tricuspid regurgitation (leaky heart valve) who are at higher risk from surgery. It aims to see if the device can reduce the leak and improve symptoms.
Atlanta, GeorgiaAges 18 years+ - NCT06508801Recruiting
Blood flow restriction to improve balance in Parkinson's
This study tests whether gently restricting blood flow to your legs during exercise can help improve balance for people with Parkinson's disease. You will do simple leg exercises while wearing a special cuff, which may strengthen muscles and improve steadiness.
San Antonio, TexasAges 40–85 - NCT06507449Enrolling by invitation
Treating Heavily Calcified Heart Blockages to Improve Microcirculation
This study is testing a technique to treat heavily calcified (hard) blockages in heart arteries. The goal is to see if a special way of preparing the blockage before placing a stent helps improve blood flow to the tiny blood vessels in the heart muscle.
KatowiceAges 18 years+ - NCT06512597Recruiting
Behavioral therapy for active Crohn's disease
This study tests whether a behavioral therapy program can help people with active Crohn's disease feel better when they start a new biologic medication. You'll get extra support to manage stress and symptoms while you and your doctor adjust your treatment.
New York, New YorkAges 18–65 - NCT06511050RecruitingPhase 1/Phase 2
Testing Lumbrokinase for Long COVID, Lyme, and Chronic Fatigue
This trial tests a supplement called Lumbrokinase (derived from earthworms) to see if it helps reduce symptoms in people with Long COVID, post-treatment Lyme disease syndrome, or ME/CFS. It may benefit those whose daily life is significantly affected by these conditions.
New York, New YorkAges 18 years+ - NCT06500975Recruiting
Long-Term Results After Vestibular Implant
This study checks how well a vestibular implant works over many years for people who already got one in earlier research at Johns Hopkins.
Baltimore, MarylandAges 22–90 - NCT06506513Recruiting
Can exercise help fatty liver disease?
This study tests whether a program of physical activity can reduce fat in the muscles and liver of people with MASLD, a type of fatty liver disease linked to metabolism. It looks at how exercise might help improve liver health.
BrusselsAges 18–70 - NCT06511752RecruitingEarly Phase 1
Support group for Spanish/English speakers with progressive aphasia
This trial tests a support group program for people with progressive aphasia (a language disorder that gets worse over time) and their caregivers. The groups meet online to share experiences and learn together.
Austin, TexasAges 18 years+ - NCT06506058Recruiting
Study on balance and brain in Parkinson's freezing of gait
This study looks at how the balance system and brain work together to cause freezing of gait in Parkinson's disease. By understanding these factors, researchers hope to find better ways to help people walk more steadily.
Minneapolis, MinnesotaAges 21–80 - NCT06511505Recruiting
Testing AI to find hidden heart conditions from ECGs
This study uses an AI tool to look at your ECG (a simple heart test) to help find early signs of atrial fibrillation (an irregular heartbeat) or structural heart disease (changes in heart structure). It aims to see if the AI can help doctors catch these conditions sooner, even in people who don't yet have symptoms.
Chicago, IllinoisAges 40 years+ - NCT06506461RecruitingPhase 1
Gene editing for sickle cell disease in young adults
This trial uses gene editing to fix your own blood stem cells, so you can stop having severe sickle cell crises. It is for young adults with frequent pain episodes or who need regular blood transfusions.
Memphis, TennesseeAges 18–24 - NCT05854615RecruitingPhase 4
Stem cell treatment for painful poor blood flow in limbs
This trial tests whether a stem cell product (Stempeucel®) is safe and effective for people with Buerger’s disease causing critical limb ischemia and foot ulcers. It may help improve healing and blood flow when other options may be limited.
Kuala LumpurAges 18–65 - NCT05854641RecruitingPhase 4
Stem cell treatment for poor blood flow in the leg ulcers
This trial tests whether a stem cell product (Stempeucel®) can improve healing and safety for people with critical limb ischemia caused by peripheral artery disease. It is for patients who cannot have (or have already tried) procedures to reopen blocked leg arteries and who have a leg ulcer and low blood-flow measurements.
Kuala LumpurAges 18–65 - NCT06480786Recruiting
Spinal cord stimulator for diabetic nerve and artery pain
This study tests if a spinal cord stimulator (a device that sends mild electrical pulses to the spine) can relieve severe leg pain caused by diabetic nerve damage and poor blood flow. It may help people who have not found enough relief from other treatments.
Omaha, NebraskaAges 19–89
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Common questions
- Are there clinical trials for general population (no specific condition or disease)?
- Yes. Clin2 currently lists 10,612 recruiting general population (no specific condition or disease) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a general population (no specific condition or disease) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a general population (no specific condition or disease) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.