Clinical trials
General Population (no Specific Condition or Disease) clinical trials
Below are recruiting general population (no specific condition or disease) clinical trials, each written for real people, not researchers. We’re tracking 10,546 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06092892RecruitingPhase 2
Upfront targeted lymph node removal for early breast cancer
This trial is for women age 45 and older with early ER-positive breast cancer that has spread to the lymph nodes under the arm. It tests a surgery approach where the main tumor and only a few key lymph nodes (rather than many) are removed.
Los Angeles, CaliforniaAges 45 years+ - NCT06092671Recruiting
Can FPCA prevent confusion in young kids after surgery?
This study tests whether a medicine called FPCA can prevent sudden confusion (delirium) in young children after surgery. If your child is having short surgery with mask anesthesia for the first time, this study may help them have a smoother recovery.
Wenzhou, ZhejiangAges 2–6 - NCT06090201Recruiting
Brain health study for severe bleeding disorders
This study uses brain scans and thinking tests to understand how severe hemophilia or von Willebrand disease affects the brain and memory over time.
LilleAges 18 years+ - NCT06083844RecruitingPhase 2
Keytruda + Avastin + chemo for ovarian cancer with minimal remaining disease
This trial tests a combination of three drugs—pembrolizumab (Keytruda, an immunotherapy), bevacizumab (Avastin, a blood-vessel blocker), and oral cyclophosphamide (a chemotherapy pill)—for women with high-grade ovarian cancer who have only tiny bits of disease left after finishing their initial treatment.
New York, New YorkAges 18 years+ - NCT06095063Recruiting
Magnetic brain stimulation for memory concerns with family Alzheimer's history
This study tests whether a type of magnetic brain stimulation (dTMS) can help people who are worried about their memory. It is for people who have a family history of Alzheimer's but are still thinking clearly.
Toronto, OntarioAges 55–70 - NCT06087029Recruiting
Improving outcomes in aortic dissection
This study tests a minimally invasive procedure called TEVAR to repair a type B aortic dissection (a tear in the wall of the main artery from your heart). It may help prevent further damage and improve recovery.
Birmingham, AlabamaAges 21 years+ - NCT06088758Recruiting
Preserving fatty livers with a machine for transplant
This study tests a new way to preserve donated livers that have extra fat (steatotic livers) using a special machine that keeps the liver healthy outside the body. If successful, it could allow more livers to be used for transplantation, helping people on the waiting list get a transplant sooner.
Boston, MassachusettsAges 18–80 - NCT06084026Recruiting
Measuring daily activity with a small leg monitor
This study uses a small device called ActivPal clipped to your leg to measure how much you move during daily life. Researchers want to compare activity levels between people with neuromuscular disorders and healthy volunteers to better understand physical activity patterns.
New York, New YorkAges 1 year+ - NCT03665831Recruiting
Deep TMS for depression and memory problems in older adults
This study tests a type of brain stimulation called Deep TMS to help reduce depression and improve or stabilize memory-related symptoms in older adults with Alzheimer’s disease. It’s mainly for people whose depression did not improve or could not be tolerated with antidepressant medicine.
Toronto, OntarioAges 60 years+ - NCT05366140Recruiting
Implanet Jazz spine fusion for adults needing thoracolumbar stabilization
This trial looks at using the Implanet Jazz system during spine fusion surgery for adults who need stabilization in the middle-to-lower back. It may help patients by improving how well the fused spine heals and stays in place.
Lexington, KentuckyAges 18–100 - NCT05918211RecruitingPhase 3
Udenafil test during exercise for teens with Fontan circulation
This trial tests whether udenafil helps teens and young people with Fontan circulation do better on exercise and breathing-related measures over time. You’d need to be on blood-thinning medicine, and be able to complete exercise testing safely.
Phoenix, ArizonaAges 12–18 - NCT05031897RecruitingPhase 2
Haplo transplant with reduced donor mismatch and radiation
This trial tests a special bone marrow/stem cell transplant approach using a partially matched family donor, along with conditioning treatment that involves radiation. It aims to help treat certain blood cancers by replacing damaged blood-forming cells with new ones from the donor.
Philadephia, PennsylvaniaAges 18 years+ - NCT06047626Recruiting
Living well with lymphoma: a fatigue and nutrition study
This study tests if eating more fruits and vegetables can help reduce persistent fatigue in people with lymphoma. You will receive questionnaires by email to track your fatigue and diet over time.
Ann Arbor, MichiganAges 18 years+ - NCT05178069RecruitingPhase 2
Probiotic supplement study for alcohol use disorder and liver injury
This Phase 2 trial studies whether a probiotic (LGG) can improve health in people with alcohol use disorder and alcohol-related liver injury. It’s not an alcohol treatment study, so participants are mainly joining to see how the supplement affects the body and liver-related outcomes.
Louisville, KentuckyAges 21–65 - NCT05000996Recruiting
Gut microbiome study for people having metabolic surgery
This study looks at your gut bacteria (your “microbiome”) around the time of metabolic surgery. It may help researchers understand how surgery affects gut health and related conditions like diabetes, blood pressure, and cholesterol.
Nashville, TennesseeAges 21–65 - NCT04164173Recruiting
Breathing therapies after heart surgery for lung overinflation
This study looks at breathing (respiratory) therapies to help after certain heart surgeries that can cause the lungs to feel overly inflated. If you’re eligible, you may receive and be assessed for how well these breathing treatments work during your recovery.
Dallas, TexasAges 18–80 - NCT05152888RecruitingPhase 4
Testing a cholesterol drug to improve heart blood flow on scans
This trial studies whether lowering LDL (“bad cholesterol”) with a PCSK-9 inhibitor (evolocumab) improves blood flow to the heart, measured by special PET scans. It’s for people over a certain age who have stable coronary artery disease and a higher risk of heart problems.
Boston, MassachusettsAges 50–90 - NCT02855554Recruiting
MRI heart scan study for specific heart conditions
This study uses a special MRI approach to measure details of your heart muscle in people with certain heart problems. It may help researchers better understand how different conditions affect the heart and how those changes can be measured.
Charleston, South CarolinaAges 18–90 - NCT01851642Recruiting
Study how lung disease affects white blood cells
This study looks at how lung disease changes a type of blood cell called white blood cells. It may help researchers understand what’s happening in the lungs and how to better monitor or treat lung problems.
Gainesville, FloridaAges 18 years+ - NCT06075745RecruitingPhase 2
CMV Vaccine Study for Liver Transplant Candidates
This trial tests a vaccine to prevent cytomegalovirus (CMV) infection in people awaiting a first liver transplant. You may be eligible if you have never been infected with CMV and are scheduled to receive a liver transplant within the next 1 to 12 months.
Birmingham, AlabamaAges 18 years+ - NCT06079216Recruiting
Music and connection for older adults
This trial uses music to help older adults in residential care feel more connected. Volunteers will attend music sessions to see if they improve mood and social bonds.
Winchester, MassachusettsAges 18–103 - NCT06071429Recruiting
Dissolvable medicine stent for leg artery disease
This trial tests a new dissolvable stent that slowly releases medicine to keep your lower-leg artery open. It is for people with severe leg pain or small wounds due to poor blood flow, and who are not eligible for other stents.
New York, New YorkAges 18 years+ - NCT06080074RecruitingPhase 2
Emergency heart-lung machine study for children with severe heart failure
This study tests a specific heart-lung machine called Cardiohelp to help children with severe heart failure. It looks at how well the machine works and whether a blood thinner (either heparin or bivalirudin) is safer and more effective.
Palo Alto, CaliforniaAges birth–16 years - NCT06063564Recruiting
Testing a digital tool to improve heart health in rural clinics
This study is testing a digital health app called PREVENT to help doctors and patients work together on heart-healthy habits like eating well and being active. It is designed for people in rural areas who want to lower their risk of heart disease.
St Louis, MissouriAges 18–64
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Common questions
- Are there clinical trials for general population (no specific condition or disease)?
- Yes. Clin2 currently lists 10,546 recruiting general population (no specific condition or disease) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a general population (no specific condition or disease) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a general population (no specific condition or disease) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.