Clinical trials
General Population (no Specific Condition or Disease) clinical trials
Below are recruiting general population (no specific condition or disease) clinical trials, each written for real people, not researchers. We’re tracking 10,548 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05797519Recruiting
Transcatheter valve replacement for leaking tricuspid valve
This trial studies a catheter-based procedure to replace the tricuspid valve in people with severe valve leakage. It aims to improve symptoms and heart function while tracking safety and effectiveness.
Sydney, New South WalesAges 18 years+ - NCT05791864RecruitingPhase 1/Phase 2
Gene therapy for vision loss in CLN2 disease
This study tests a new gene therapy, TTX-381, given as an eye injection to slow or stop vision loss in children with CLN2 disease. It is for children who are already receiving enzyme replacement therapy and are in a stage of rapid vision decline.
HamburgAges 2–7 - NCT05317390Recruiting
Tests an AI tool to diagnose isolated dystonia
This trial checks whether an AI (software) called DystoniaNet can accurately identify isolated dystonia using information from your evaluation, and compares its results to standard diagnosis. If you have focal, segmental, or generalized dystonia, this study may help improve faster and more accurate diagnosis in the future.
Boston, MassachusettsAges Any age - NCT05776030Recruiting
Test of different-speed ergonomic wheelchairs for daily users
This study tests a wheelchair design that can better match how you move and sit while using a manual wheelchair every day. You may be able to try different wheelchair setups if you meet the safety, seating, and body-size requirements.
Minneapolis, MinnesotaAges 18 years+ - NCT05777993Enrolling by invitationPhase 4
Continued access to mitapivat for prior study participants
This study provides continued access to the drug mitapivat for people who have already been in a mitapativ study and are benefiting from it.
Anderlecht, Brussels CapitalAges 18 years+ - NCT05750901Recruiting
Laser treatment study for loose skin or scars
This study tests a laser procedure to improve visible skin looseness or scars. You may be eligible if you have a targeted skin area needing treatment and can follow scheduled visits and after-care.
Boca Raton, FloridaAges 18–85 - NCT05770349Recruiting
Heart failure patients having bypass surgery are studied
This study looks at tiny structures inside heart muscle cells (especially “power stations” in the cells) in people with certain types of heart failure who are getting coronary bypass surgery. It may help researchers better understand what changes happen in the heart and how this could guide future care.
TomskAges 18 years+ - NCT05763732Recruiting
Testing how brain stimulation affects walking in Parkinson’s
This trial looks at how turning on and using a specific Parkinson’s brain stimulator affects your walking. It may help doctors understand what changes in gait (walking) can happen with this device and settings.
Baltimore, MarylandAges 18–89 - NCT05757310RecruitingPhase 1
Stem cell transplant with lower-intensity chemo for severe aplastic anemia
This Phase 1 trial tests a “lower-intensity” chemotherapy plan followed by a stem cell transplant from a related half-match donor for severe aplastic anemia that has returned or did not respond to prior medicines. It aims to see if this approach is safe and works well enough to help your blood counts recover.
Duarte, CaliforniaAges Up to 75 years - NCT05751967RecruitingPhase 3
Fenofibrate plus ursodeoxycholic acid for primary biliary cholangitis
This trial tests whether adding fenofibrate to ursodeoxycholic acid (UDCA) can improve liver test results in people with primary biliary cholangitis (PBC) who did not respond enough to UDCA alone. It aims to see if the combination works better and is safe for adults with persistent, abnormal liver markers.
Lanzhou, GansuAges 18–75 - NCT05748613Recruiting
Anxiety-focused skills training for people with Alzheimer’s
This study tests a treatment aimed at reducing anxiety in people who have Alzheimer’s disease or related memory problems. It also involves a support partner, and the goal is to see whether the program can lower anxiety and stress day-to-day.
Tallahassee, FloridaAges 60 years+ - NCT05770661Recruiting
Study of eye growth length in children in China
This study looks at how a child’s eye “length” changes as they grow. It may help researchers understand patterns in eye development and who may be at higher risk for future vision problems.
Shanghai, Shanghai MunicipalityAges 3–18 - NCT05775224Enrolling by invitation
Join a research data hub for sickle cell or multiple myeloma
This study builds a database of people with sickle cell disease and/or active multiple myeloma (diagnosed or treated in recent years). It may help researchers learn how these illnesses behave and support better future studies or treatments.
Washington D.C., District of ColumbiaAges Any age - NCT05747976Recruiting
Study for children with very high body size measurements
This study is building a program database for children who have unusually high body size measurements for their age. By collecting genetic and health information, researchers hope to better understand causes of obesity and guide care.
Houston, TexasAges Any age - NCT05750498Recruiting
Study to improve outcomes in autoimmune liver disease
This trial tests approaches to improve health outcomes for people with autoimmune liver diseases. It includes specific autoimmune conditions affecting the liver and bile ducts, and it may help your care team learn what works best for these illnesses.
Palo Alto, CaliforniaAges Any age - NCT05748197RecruitingPhase 1
Study of ADCLEC.syn1 for relapsed or resistant AML
This Phase 1 study tests ADCLEC.syn1, a new treatment made from a patient’s immune cells, in adults with relapsed or refractory acute myeloid leukemia (AML). The goal is to see how safe it is and how well it may work, especially after standard treatments have not helped.
Basking Ridge, New JerseyAges 18 years+ - NCT05749822RecruitingPhase 2/Phase 3
Fenofibrate for primary biliary cholangitis with stable cirrhosis
This trial studies whether fenofibrate (a cholesterol medicine) can improve outcomes in people with primary biliary cholangitis (PBC) who already take ursodeoxycholic acid (UDCA) but still have abnormal liver blood tests. It specifically looks at people with “compensated” (stable) cirrhosis—meaning the liver disease is present but not causing severe complications right now.
Beijing, Beijing MunicipalityAges 18–75 - NCT05718323RecruitingPhase 2
Niraparib with immunotherapy maintenance for advanced small-cell lung cancer
This trial tests whether adding niraparib (a pill cancer medicine) to ongoing immunotherapy maintenance can help people with advanced small-cell lung cancer live longer or better. It is for tumors that show a specific protein marker (SLFN11) and that did not worsen after standard first-line chemo-immunotherapy.
AngersAges 18 years+ - NCT05731141Recruiting
Study of lymphatic birthmarks and related genetic conditions
This study follows people who have lymphatic anomalies (lymphatic birthmarks) and sometimes related vascular or genetic conditions. It aims to better understand how these problems develop and what genetic causes may be involved.
Bethesda, MarylandAges 1 day–100 years - NCT05732480Recruiting
Studying how gut bacteria affect gallstone disease
This study looks at gut bacteria (your microbiome) in people with gallstones to better understand what’s going on in the body. It includes adults having gallbladder removal surgery, and it may help researchers find better ways to predict or treat gallstone disease.
Ashford, KentAges 18 years+ - NCT05711394RecruitingPhase 3
Atogepant for preventing episodic migraine in children
This study tests whether an oral medicine called atogepant can reduce migraine activity in children ages 6–17 and checks its side effects. It’s meant for kids with episodic migraine (not the more constant types) who may benefit from preventive treatment.
Huntsville, AlabamaAges 6–17 - NCT05734521Recruiting
Study of avalglucosidase alfa use during pregnancy
This study collects safety information about avalglucosidase alfa when it’s taken during pregnancy and/or while breastfeeding. If you (or your baby) were exposed to this medicine and consent to be in a pregnancy safety registry, your information may help researchers better understand risks.
Bridgewater, New JerseyAges Any age - NCT04908696Recruiting
Treatment study for laryngeal and hypopharyngeal cancers
This trial tests treatment approaches for people with cancers of the voice box (larynx) or lower throat (hypopharynx). It may help by finding which treatment strategy works best for different tumor locations and cancer stages.
Shanghai, Shanghai MunicipalityAges 18–90 - NCT04871607RecruitingPhase 2
Yttrium antibody plus chemotherapy for hard-to-treat Hodgkin lymphoma
This trial studies a targeted antibody therapy with yttrium, combined with intensive chemotherapy, for adults whose Hodgkin lymphoma did not respond well or came back. It may help by delivering cancer-killing radiation directly to lymphoma cells and preparing the body for treatment after transplant conditioning.
Duarte, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for general population (no specific condition or disease)?
- Yes. Clin2 currently lists 10,548 recruiting general population (no specific condition or disease) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a general population (no specific condition or disease) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a general population (no specific condition or disease) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.