Clinical trials
General Population (no Specific Condition or Disease) clinical trials
Below are recruiting general population (no specific condition or disease) clinical trials, each written for real people, not researchers. We’re tracking 10,548 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05545865Recruiting
Test how grape-based drinks affect blood flow response
This study tests whether a grape product (“Chardonnay Marc”) can change how your blood vessels respond to stress, measured with a finger sensor. It may help researchers understand how diet influences circulation in people with a low baseline blood-flow response.
Davis, CaliforniaAges 30–50 - NCT05531474Recruiting
Bariatric surgery to lower future heart and stroke events
This trial looks at whether weight-loss surgery can reduce the chances of heart attack, stroke, or other serious heart problems in people at higher heart risk. You might be offered surgery and followed over time to see if cardiovascular events are reduced.
Hamilton, OntarioAges 18 years+ - NCT05519046Recruiting
Test a heart pacing treatment for Chagas-related heart failure
This study looks at a heart treatment called cardiac contractility modulation in people with Chagas heart disease who have moderate symptoms and weak heart pumping. It aims to see whether this therapy improves heart function and related outcomes in the right patients.
São Paulo, São PauloAges 18–75 - NCT05521503Recruiting
Collecting heart tissue samples for a shared research database
This trial builds a database by collecting and storing biopsy or biopsy-related samples from adults being evaluated for certain heart conditions. It may help researchers study heart disease and amyloidosis by making past tissue samples easier to access for future research.
Lexington, KentuckyAges 18 years+ - NCT05465044Recruiting
Twice-weekly dialysis for veterans starting kidney treatment
This study compares starting hemodialysis two times per week versus three times per week for veterans in their first year of dialysis. It aims to see if a less frequent schedule can be just as safe and effective for those who still make urine.
Long Beach, CaliforniaAges 18 years+ - NCT05470504RecruitingPhase 2
Pegvisomant for severe insulin resistance from rare fat or gene problems
This Phase 2 study tests pegvisomant, a medicine that blocks growth hormone, to see if it can improve severe insulin resistance in people with a specific genetic cause or a rare fat distribution condition. If you fit the rare diagnosis, the study may help clarify whether growth-hormone blocking can improve blood sugar and related health markers.
Bethesda, MarylandAges 18–70 - NCT05470491RecruitingPhase 1/Phase 2
Haploidentical bone marrow transplant with GVHD prevention drugs
This trial tests a reduced-intensity bone marrow transplant from a related donor (haploidentical), using medicines to help prevent a serious complication called GVHD. It is for people with certain blood cancers and aims to improve outcomes by balancing transplant benefit with lower treatment intensity.
Bethesda, MarylandAges 12–120 - NCT02022943Recruiting
Join an Alzheimer's prevention registry website
This trial builds a registry so researchers can contact you about future Alzheimer’s studies. It mainly requires agreeing to the registry’s website terms and conditions.
Phoenix, ArizonaAges 18–110 - NCT05485961RecruitingPhase 2/Phase 3
Clazakizumab for kidney failure patients on dialysis
This study tests an experimental drug called clazakizumab (CSL300) to see if it can reduce inflammation and lower the risk of heart problems in people with kidney failure who are on dialysis. It may help if you have diabetes or heart disease and have high inflammation levels.
Decatur, AlabamaAges 18 years+ - NCT05488431RecruitingPhase 2
Bempedoic acid to lower cholesterol and inflammation in HIV
This Phase 2 trial studies whether bempedoic acid can lower cholesterol and inflammation in people with HIV who are already on effective HIV medications. It may help reduce signs of artery inflammation that can contribute to heart and stroke risk.
Los Angeles, CaliforniaAges 40 years+ - NCT05462574Recruiting
MRI study of heart fat in pulmonary arterial hypertension
This trial uses MRI (and an additional MRI measurement called MRS) to study fat in the right side of the heart in people with pulmonary arterial hypertension (PAH). It may help researchers understand what’s going on in PAH and how it relates to symptoms and exercise ability.
Nashville, TennesseeAges 18 years+ - NCT05491668Recruiting
Testing heart artery narrowing before planned stent procedure
This study checks how severely blocked a coronary artery is using measurements taken during a planned heart catheterization, to help guide whether and how to do a stent (PCI). It may help doctors choose the best treatment plan for people with about 70% or more narrowing.
Boston, MassachusettsAges 18 years+ - NCT05472597Enrolling by invitation
Follow-up study about heart health after pregnancy
This study is continuing follow-up interviews and surveys to learn about heart health after pregnancy. If you already took part before, it may help researchers understand how postpartum health changes over time.
Orange, CaliforniaAges 18 years+ - NCT05473871Recruiting
Help churches deliver low-exercise physical activity programs
This trial tests a program to help churches support people who currently get little exercise to become more active. You may be invited to join activities through your church over the next 18 months.
San Diego, CaliforniaAges 18–65 - NCT05489575Recruiting
CPAP machine for high blood pressure when lying down at night
This study tests whether using a CPAP breathing machine at night can lower high blood pressure that happens while you sleep. It targets people with nervous-system problems that affect blood pressure changes when standing.
Nashville, TennesseeAges 40–80 - NCT05462600Enrolling by invitation
Breathing monitoring test in non-smokers
This study measures how you breathe and how well oxygen and carbon dioxide move in and out of your lungs. It’s mainly a monitoring study to help researchers understand breathing patterns during a breathing test.
La Jolla, CaliforniaAges 18 years+ - NCT05464186Recruiting
Whole versus nonfat milk effects on kids’ body composition
This study compares whole milk vs nonfat milk to see how each affects body composition (such as fat and lean mass) in children. It may help families understand whether milk type makes a difference for healthy growth.
Boston, MassachusettsAges 9–12 - NCT05461729Recruiting
Testing a heart rehab timing prediction tool after a heart attack
This study follows people with coronary artery disease who are starting a structured heart rehabilitation program after a heart attack or heart procedures. The trial tests whether it can predict and improve the right timing or planning for cardiac rehab.
Ennepetal, North Rhine-WestphaliaAges 18 years+ - NCT05466825Recruiting
Using health data to study cardiovascular risk
This study brings together existing health information to understand how common heart-risk factors relate to heart outcomes. It may help improve how future risk is predicted and prevented, especially in people who have not yet had heart disease.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT05463692Enrolling by invitation
Study of STI prevention and sexual health in Alabama women
This study follows women in Alabama to better understand sexual health and STI prevention over time. You may be able to join if you recently had an STI report and you’re currently negative for HIV, gonorrhea, and syphilis.
Birmingham, AlabamaAges 18–89 - NCT05484557Recruiting
Apixaban vs enoxaparin to prevent blood clots after spinal cord injury
This trial studies whether apixaban works as well as enoxaparin to prevent dangerous blood clots after spinal cord injury. If you qualify, you would take one of these medicines to lower clot risk during the recovery period.
RaananaAges 18 years+ - NCT05495035RecruitingPhase 1
Olverembatinib plus APG-2575 for children with resistant leukemia
This study tests a new combination of two oral drugs (olverembatinib and APG-2575) for children with a type of leukemia (Ph+ ALL) that has returned or stopped responding to standard treatments. The goal is to see if this combination is safe and effective.
Hefei, AnhuiAges 1–18 - NCT05487612Recruiting
MiECC heart-lung machine vs standard bypass during heart surgery
This trial compares a newer heart-lung machine setup (MiECC) with the usual bypass technique during certain heart operations. It may help see whether MiECC changes outcomes like the need for blood transfusions or recovery after surgery.
TorontoAges 18–85 - NCT05461092RecruitingEarly Phase 1
Nerve blocks to improve pain control after spinal fusion
This early-stage study tests whether a regional nerve block can improve pain control and recovery for older adults having elective lumbar spinal fusion. If you qualify, you may receive a special pain-control injection during surgery to reduce opioid needs and improve recovery comfort.
Iowa City, IowaAges 65 years+
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Common questions
- Are there clinical trials for general population (no specific condition or disease)?
- Yes. Clin2 currently lists 10,548 recruiting general population (no specific condition or disease) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a general population (no specific condition or disease) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a general population (no specific condition or disease) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.