Clinical trials
General Population (no Specific Condition or Disease) clinical trials
Below are recruiting general population (no specific condition or disease) clinical trials, each written for real people, not researchers. We’re tracking 10,548 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05307731RecruitingPhase 4
Fingolimod for adults with type 2 diabetes
This trial studies whether fingolimod can improve diabetes in adults with type 2 diabetes who are not yet on many medications. It will mainly check whether the drug is safe and whether it can help control blood sugar over time.
ShenyangAges 18–70 - NCT05285917RecruitingPhase 3
Hydroxyurea safety study for young children with sickle cell
This trial tests a way to use hydroxyurea more safely and effectively in children with sickle cell anemia. It may help doctors fine-tune dosing to reduce complications and side effects.
LuandaAges 6 months–12 years - NCT05282550RecruitingPhase 2
Trazodone trial to improve sleep in early Alzheimer’s
This study tests whether the sleep medicine trazodone can improve thinking and memory in people with early Alzheimer’s-related changes who also have sleep problems. If better sleep helps the brain, it may improve memory test results over time.
Baltimore, MarylandAges 55 years+ - NCT05265299RecruitingPhase 3
Testing the right aspirin dose for COPD symptoms
This Phase 3 trial studies which aspirin dose works best in people with COPD, with the goal of improving disease control. You may be asked to take aspirin and be monitored for safety, especially bleeding risk and heart/brain history.
Baltimore, MarylandAges 40–80 - NCT05301101Recruiting
Re-irradiation planning for tumors near previously treated organs
This study tests a more personalized way to plan “re-irradiation,” meaning giving radiation again in an area that was already treated before. It aims to better calculate organ risk to reduce harmful side effects while treating cancer.
Milwaukee, WisconsinAges 18 years+ - NCT05296889Recruiting
Safety follow-up for Ennovate cervical device
This study checks how safely and effectively a cervical device (Ennovate® Cervical) works after it’s been used in routine care. It may help by monitoring real-world safety and performance over time.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT05265273RecruitingPhase 2/Phase 3
Nipocalimab for children with generalized myasthenia gravis
This trial studies nipocalimab, an immune-focused medicine, to see if it can improve generalized myasthenia gravis (gMG) in children ages 2 to under 18. It may help reduce weakness caused by this autoimmune muscle disease, but you must meet specific antibody and health requirements.
Phoenix, ArizonaAges 2–17 - NCT05292794Recruiting
CereGate therapy for freezing of gait in Parkinson’s
This trial tests whether CereGate therapy can reduce “freezing of gait,” a walking problem, in people with Parkinson’s disease who already have deep brain stimulation (DBS). If you meet the device and medication stability requirements, the study may help your walking and movement symptoms measured during testing.
Redwood City, CaliforniaAges 21–80 - NCT05266872Recruiting
Earlier diagnosis and better treatment study for Parkinson’s
This study is looking to improve how Parkinson’s and related brain conditions are identified and treated sooner. You may be asked to share your health information and provide blood or other samples, and possibly have procedures like a spinal fluid test or a small skin sample.
LuxembourgAges 18 years+ - NCT04179695Recruiting
Testing a new communication aid to improve patient-centered care
This study tests a new tool meant to help patients and healthcare teams communicate better and support “patient-centered care.” You may be invited to use the tool and complete study activities during your neurology care visits.
LilleAges 18–90 - NCT05201469RecruitingPhase 2
VIB4920 for lupus kidney inflammation not responding well enough
This Phase 2 study tests VIB4920 to treat active lupus nephritis, a type of kidney disease caused by lupus. It may help reduce kidney inflammation and improve kidney outcomes in people with active disease despite standard care.
La Jolla, CaliforniaAges 18 years+ - NCT05199870Enrolling by invitation
Long-term follow-up for specific hip implant parts
This study follows people who had a particular bipolar hip implant (RingLoc cup and/or Endo II head) placed during a hemi-hip replacement surgery at least 8 years ago. It checks how well the implants keep working over time and why.
Falls Church, VirginiaAges 18 years+ - NCT05238740Recruiting
Compare fusion results after two spine surgeries with added biologics
This study compares two types of spine surgery (ALIF or XLIF) for one spinal level, and tests how well the bones fuse when a specific bone-forming product is used. It also looks at how patients feel and function after surgery.
BernAges 18–70 - NCT05231785RecruitingPhase 1
Test drug safety for early Alzheimer’s memory trouble
This Phase 1 trial tests how safe and tolerable ALN-APP is in people with early Alzheimer’s-related mild memory impairment or mild dementia. It may help researchers find a treatment path for early Alzheimer’s, while closely monitoring side effects and basic health markers.
La Jolla, CaliforniaAges 18 years+ - NCT05239364Recruiting
Ablation for an abnormal heart rhythm after prior AF surgery
This trial tests a procedure to “ablate” (treat) a specific fast heart rhythm in the upper chambers of the heart that happens after previous atrial fibrillation (AF) ablation or heart surgery. It may help by stopping the rhythm and reducing symptoms, while doctors check how well the targeted mapping and ablation work.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT05215171Recruiting
Study breathing and blood changes after 9/11 exposure
This study looks at how breathing problems and blood vessel/heart issues may happen after World Trade Center (WTC) dust exposure. It uses blood samples and breathing tests to understand who may be affected and to compare people with and without WTC-related airway reactivity.
New York, New YorkAges 21–90 - NCT05212129Recruiting
Stimulation of the ear nerve to help gut symptoms
This study tests whether stimulating a nerve in the ear (called auricular vagal nerve stimulation) can improve upper gut symptoms in teens who may have hypermobile Ehlers-Danlos syndrome (hEDS) or hypermobile spectrum disorder (HSD). It also checks whether this treatment helps nerves that control the body (autonomic nervous system) and how well the gut moves.
Milwaukee, WisconsinAges 10–18 - NCT05250375Recruiting
Study of mitochondrial muscle diseases over time
This natural history study follows children and adults with suspected or confirmed mitochondrial myopathy to better understand symptoms and how the condition changes. It may also include healthy participants to compare test results and improve future treatments.
Philadelphia, PennsylvaniaAges birth–100 years - NCT05240885Recruiting
Metabolic and functional effects of aging in health and disease
This study looks at how aging affects your body's metabolism and physical function, especially if you have heart failure or have recently been in the hospital. It may help doctors understand how to better support recovery and health as we age.
College Station, TexasAges 50 years+ - NCT05244486Recruiting
RestoreX traction therapy after prostate surgery
This trial studies whether RestoreX penile traction can help preserve erectile function after a prostatectomy (surgery to remove the prostate), especially when nerves are spared. If you qualify, you may be asked to use the device and be followed over time to see how erections change.
Phoenix, ArizonaAges 18 years+ - NCT05223530Recruiting
Study of how pregnancy programs future child health
This study follows mothers who previously joined two specific pregnancy research programs, to understand why some children may be more likely to develop weight and heart-related health problems later. If you were part of those original studies, your information could help researchers look for early predictors and prevention ideas.
HelsinkiAges 11–55 - NCT05230173Recruiting
Treat to endoscopic remission in inflammatory bowel disease
This study tests whether switching to a different treatment for inflammatory bowel disease (IBD) can achieve healing of the gut lining. It is for people whose symptoms are under control but who still have significant inflammation in their bowel.
Scottsdale, ArizonaAges 18 years+ - NCT05222620RecruitingPhase 2
SRS methods for untreated brain metastases under 4 cm
This trial compares two stereotactic radiation strategies for patients who have intact (not previously radiated) brain metastases that are limited in size. It aims to see which approach works best in controlling the cancer while reducing side effects.
Scottsdale, ArizonaAges 18 years+ - NCT05233631Enrolling by invitation
Registry for people who had endoscopic ultrasound
This trial is a registry that collects information from people who undergo a procedure called endoscopic ultrasound (also known as EUS) at the study center. It helps doctors understand what care is used and what outcomes happen over time.
Dallas, TexasAges 18 years+
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Common questions
- Are there clinical trials for general population (no specific condition or disease)?
- Yes. Clin2 currently lists 10,548 recruiting general population (no specific condition or disease) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a general population (no specific condition or disease) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a general population (no specific condition or disease) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.