Clinical trials
Genotype clinical trials
Below are recruiting genotype clinical trials, each written for real people, not researchers. We’re tracking 96 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04156893RecruitingPhase 1/Phase 2
RH-matched blood transfusions for sickle cell patients
This study tests whether giving red blood cells matched to your child’s RH (a blood marker) can improve safety and fit for people with sickle cell disease who need regular transfusions. It may help reduce mismatches by using blood units selected to match the child’s blood type more closely.
Philadelphia, PennsylvaniaAges 6 months+ - NCT06500351Recruiting
Postpartum hypertension gene and aging study
This study looks at two things in women with postpartum hypertension (high blood pressure after giving birth). It tests a gene called Renalase and measures the length of telomeres (a marker of cell aging) to see if they are linked to this condition.
SohagAges 18–45 - NCT06529536RecruitingPhase 4
Personalized tacrolimus dosing for children after transplant
This trial tests a new way to personalize tacrolimus dosing for children after a kidney, liver, or heart transplant. It uses genetic information and a formula to find the best starting dose, aiming to improve outcomes.
Melbourne, VictoriaAges 1–18 - NCT06839833Recruiting
APOL1 gene test study for trial volunteers
This study checks if a new genetic test for the APOL1 gene works correctly. It uses samples from people who have already joined another drug trial.
Durham, North CarolinaAges 18–70 - NCT04974138RecruitingPhase 4
Preventing first stroke in people with high-risk blood pressure
This trial tests whether a study medicine regimen can help prevent a first stroke in people with hard-to-control “high homocysteine” risk factors linked to a specific gene type. You may qualify if you have certain blood pressure levels, a specific MTHFR gene result, and related blood test findings.
Bengbu, AnhuiAges 45–74 - NCT04974151RecruitingPhase 4
Prevention trial for stroke risk in people with high blood pressure
This trial tests an approach to prevent first-time stroke and heart problems in people with high blood pressure who also have a specific genetic test result (MTHFR 677 TT). It may help by lowering risk before a first stroke happens.
Bengbu, AnhuiAges 45–74 - NCT05385406Recruiting
HPV screening with different ways to check for cervical problems
This trial tests two cervical screening approaches to find early signs of HPV-related changes. It may help by improving how results are sorted into “needs follow-up” versus “routine care,” especially for women with different HPV patterns.
Dschang, MenouaAges 25–49 - NCT06283888RecruitingPhase 4
Choosing a blood thinner based on your genes after complex heart treatment
This trial tests whether choosing a blood thinner based on your DNA can prevent more heart problems. If you've had a complex heart procedure, you may be able to get a medication that works best for your body.
Zunyi, GuizhouAges 18–80 - NCT06292117Recruiting
Genotype-guided antiplatelet therapy for stroke patients
This trial tests whether using a rapid genetic test to choose antiplatelet medication can improve outcomes for people who have had a stroke or mini-stroke. The test checks a gene that affects how your body processes a common antiplatelet drug, so your doctors can pick the safest and most effective medicine for you.
Charlottesville, VirginiaAges 18 years+ - NCT06791421Recruiting
Using AI to Predict Genes from Health Records
This study is testing an AI tool that uses your health records—like medical history, lab tests, and scans—to predict your genetic information. You may be eligible if you have complete health records and agree to let researchers use your data for this prediction analysis.
Guangzhou, GuangdongAges Any age - NCT06881771Recruiting
Tracking Fuchs' dystrophy progression and genetics in the UK
This study follows people with Fuchs' endothelial corneal dystrophy over time to see how the condition changes and how it relates to their genes. It aims to help doctors better predict and manage the disease.
LondonAges 18 years+ - NCT07138963Recruiting
Gene study in children with congenital muscle weakness
This study looks at how genes affect symptoms in children with congenital myopathies or congenital muscular dystrophies. It may help doctors better understand these conditions.
CairoAges 1–18 - NCT07368777Recruiting
Genetics-based diet counseling vs standard diet for weight loss
This trial compares two types of diet counseling—one based on your genetic makeup and the other standard advice—to see which helps more with weight loss and reducing body fat. It is for adults who are overweight or obese and willing to follow a diet program.
MarousiAges 18–65 - NCT01145196Recruiting
Study drug eye damage and genes in Plaquenil users
This study looks at how Plaquenil (hydroxychloroquine) can harm the retina (the eye’s light-sensing layer) and whether genetics affect who gets affected. You may help by sharing medical details and providing an eye-related blood sample so researchers can compare gene patterns to eye findings.
Bethesda, MarylandAges 18–120 - NCT06406465RecruitingPhase 2
Belinostat trial for neuroendocrine cancer based on genetics
This trial tests a drug called belinostat, possibly combined with other drugs, based on your genetic makeup. It aims to find the right dose for people with a rare and aggressive neuroendocrine cancer that started outside the lungs.
Bethesda, MarylandAges 18–120 - NCT05789173RecruitingEarly Phase 1
Testing how genetics affect drug levels with methadone
This early study tests how a person’s genetic makeup may change how fast certain medicines move through the body. It compares drug levels when combined with methadone and tizanidine, aiming to understand safer dosing and effects.
Indianapolis, IndianaAges 18–65 - NCT05367609Recruiting
Personalized pain plan for kids getting spine fusion surgery
This trial tests a personalized plan to manage pain around the time of pediatric posterior-lateral spinal fusion surgery. It aims to improve comfort and reduce the chance of pain or opioid problems after surgery by tailoring pain medicines to the child.
San Francisco, CaliforniaAges 10–21 - NCT06801977Recruiting
Chinese lung cancer study for a rare type
This study is collecting information from people with a rare lung cancer called pulmonary lymphoepithelioma-like carcinoma (a type of lung tumor that looks like certain head and neck cancers). It aims to learn more about the disease and how to better treat it.
Foshan, GuangdongAges 18 years+ - NCT06515587Recruiting
Lewis antigen test for pancreatic cancer prognosis
This study looks at how a special blood test (Lewis antigen) combined with a standard CA19-9 test might help predict the outlook for people with pancreatic cancer. You will give a small extra blood sample and have routine follow-up tests.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05380531Recruiting
Personalized pain plan for planned C-section using opioid options
This trial tests a personalized approach to pain control during and after a scheduled C-section. It may help by matching pain medicine choices to each person’s needs, including the use of in-hospital opioids for relief.
Indianapolis, IndianaAges 18 years+ - NCT04989751Enrolling by invitation
Study of gene patterns in limb-girdle muscle weakness
This study looks at how specific gene changes relate to the pattern of muscle weakness in people with limb-girdle muscular dystrophy (LGMD). It may help doctors better understand the condition and improve future care.
ShanghaiAges 10 years+ - NCT03024775Recruiting
Study wheat triggers in people with non-celiac wheat sensitivity
This study looks at how different types (genotypes) of wheat affect gut symptoms in people who react to wheat but do not have celiac disease. It may help clarify which wheat triggers symptoms and how to confirm the trigger in a structured food challenge.
Sciacca, AgrigentoAges 18–65 - NCT06824987RecruitingPhase 2
Study of AZD2373 for APOL1-related kidney disease
This trial tests an experimental drug (AZD2373) for people with kidney disease caused by APOL1 gene changes. It aims to find the safest and most effective dose to slow kidney damage.
Alabaster, AlabamaAges 18–65 - NCT06354322Recruiting
Genetic study for unclassified autoinflammatory disease or AA amyloidosis
This study looks for genetic causes of hard-to-diagnose autoinflammatory diseases or a related condition called AA amyloidosis. It aims to find answers for people whose condition does not fit any known type, by studying their genes and medical history.
ParisAges 3–80
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Common questions
- Are there clinical trials for genotype?
- Yes. Clin2 currently lists 96 recruiting genotype studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a genotype trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a genotype trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.