Clinical trials
GERD (Gastroesophageal Reflux Disease) clinical trials
Below are recruiting gerd (gastroesophageal reflux disease) clinical trials, each written for real people, not researchers. We’re tracking 43 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06928350Recruiting
Normal esophagus readings in healthy Indian adults
This trial is studying normal acid and fluid movement in the esophagus of healthy people in India. It will help doctors better understand what is typical, which may improve care for people with acid reflux or other swallowing issues.
Hyderabad, TelanganaAges 18–50 - NCT04255693Recruiting
Real-life reflux study of diet and behavior changes
This study looks at how following specific diet and behavior changes affects symptoms of acid reflux (heartburn/regurgitation) in everyday life. It may help you understand what lifestyle steps improve reflux and how symptoms change over time.
MoscowAges 18–80 - NCT06613438Recruiting
New wearable device for GERD symptoms
This study tests a new wearable device (eGERD) that aims to reduce symptoms of GERD (heartburn and regurgitation). The trial will check if the device is safe and works well without needing medication.
Chicago, IllinoisAges 22–75 - NCT06255886RecruitingPhase 4
Treatment for acid reflux in babies under 1 year
This trial tests a treatment for babies under 1 year old who have frequent and troublesome reflux (GERD). It aims to find a safe and effective way to reduce symptoms like crying, feeding problems, and breathing pauses.
Aabenraa, Region SyddanmarkAges 1 month–1 year - NCT05678491Enrolling by invitation
Endoscopic treatment for reflux after gastric sleeve surgery
This trial studies an endoscopic procedure to treat gastroesophageal reflux disease (GERD) in people who had gastric sleeve surgery. It may help if reflux symptoms are not controlled on once-daily acid medicine (PPI) or if you cannot tolerate it and want an alternative.
TrondheimAges 18–70 - NCT05216133Enrolling by invitation
Study WTC lung and reflux markers using noninvasive tests
This study looks at blood “biomarkers” and breathing/acid-reflux measurements in FDNY workers exposed to the 9/11 site to understand airway disease, Barrett’s esophagus, and reflux. It may help identify which people have hidden (underdiagnosed) reflux or lung involvement after 9/11.
New York, New YorkAges 37–90 - NCT04960566Enrolling by invitation
Behavior therapy for reflux symptoms tied to stress responses
This study tests a behavioral approach for people with GERD whose reflux symptoms keep coming back even after they tried an acid-blocking medicine (a PPI). It aims to help by targeting stress-related body responses that may worsen symptoms.
Chicago, IllinoisAges 18–80 - NCT04506593Recruiting
GI Motility diagnosis registry for people with digestion movement problems
This trial is a registry, meaning it collects information about people being evaluated for problems with how the gut moves. It may help doctors better diagnose gastrointestinal motility disorders in the future.
Indianapolis, IndianaAges Any age - NCT03853772Enrolling by invitation
Heartburn registry for long-term symptom and care follow-up
This registry enrolls people with GERD (chronic heartburn/reflux) to track symptoms and treatments over time for up to 5 years. It may help researchers understand what works best in everyday care, and you’ll be asked to complete check-in surveys.
Orange, CaliforniaAges 18 years+ - NCT00260585Recruiting
Esophageal risk and tissue registry study
This study collects information and, if you already need blood tests or procedures, may take extra small tissue samples (biopsies) to better understand esophageal-related conditions. It may help researchers learn about risk and future management for people with certain esophagus or reflux-related diagnoses.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06783751Recruiting
New surgical method to reduce acid reflux after weight loss surgery
This trial tests a modified version of sleeve gastrectomy that aims to reduce the risk of acid reflux (GERD) after surgery. It is for people aged 18–65 with a BMI between 35 and 55 who already have some degree of GERD and are planning to have weight loss surgery.
Orange, CaliforniaAges 18–65 - NCT07708220Recruiting
Laparoscopic treatment for acid reflux in children
This trial tests a minimally invasive surgery to treat gastroesophageal reflux disease (GERD) in children. It aims to reduce symptoms and improve quality of life for kids who have not had prior reflux surgery.
TantaAges 2–18 - NCT05697393Recruiting
Testing a pressure band to ease GERD throat and cough symptoms
This study tests whether using an “external Shaker pressure band” can reduce GERD symptoms that affect the throat and airway, like chronic cough, choking, or food coming back up. It also checks whether these people can safely tolerate the study measurements through the nose.
Milwaukee, WisconsinAges 18–85 - NCT07707011Enrolling by invitation
Comparing two test-guided treatments for acid reflux
This trial compares two ways to choose the best treatment for people with frequent acid reflux. It tests whether using a simple test (called PCAB-guided) is as good as a more detailed test (called physiologic test-guided) for deciding on the right medicine. The goal is to find a more practical and effective approach.
Bangkok Noi, BangkokAges 18–70 - NCT07291700Recruiting
Talcid for acid rebound after stopping long-term PPI therapy
This study tests whether Talcid chewable tablets can relieve the acid reflux symptoms that often happen when you stop taking a long-term daily acid-reducing medicine (like omeprazole). It is for people whose doctor says they no longer need that medicine.
LeverkusenAges 18 years+ - NCT05696184Recruiting
Studying why reflux reaches the throat and what stops it
This study looks at the “upward reflux” that can irritate the throat and sometimes worsen symptoms like cough or asthma. It aims to understand the mechanisms that prevent or allow throat reflux, which may lead to better ways to manage symptoms.
Milwaukee, WisconsinAges 18–85 - NCT07158008Recruiting
Weight loss surgery for people with obesity and heartburn
This study compares two weight-loss surgeries for people who have both obesity and severe heartburn or GERD. One surgery combines part of the stomach removal with an anti-reflux wrap, while the other reroutes the stomach to help with weight loss and reflux.
KrakowAges 18–65 - NCT06939465Recruiting
Cognitive therapy for throat and chest symptoms
This trial tests if a cognitive-behavioral therapy (a type of talk therapy that helps change thoughts and habits) can improve chronic throat and chest symptoms like heartburn, reflux, lump in throat, or trouble swallowing. It is for people who have these symptoms without a known structural problem in the esophagus.
Hualien CityAges 18–75 - NCT06778824Recruiting
Brain-gut medicine trial for chronic esophagus issues
This trial tests a type of brain-gut medicine to see if it helps with ongoing esophagus problems like heartburn, acid reflux, a lump in the throat, trouble swallowing, or chest pain. It might help if other treatments haven't worked well.
Hualien CityAges 18–75
Hear when a new GERD (Gastroesophageal Reflux Disease) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for gerd (gastroesophageal reflux disease)?
- Yes. Clin2 currently lists 43 recruiting gerd (gastroesophageal reflux disease) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gerd (gastroesophageal reflux disease) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gerd (gastroesophageal reflux disease) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.