Clinical trials · Boston, MA
Heart Diseases clinical trials in Boston
We’re tracking 46 recruiting heart diseases studies with a site in or near Boston — including Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Boston
- NCT06217302RecruitingPhase 3
Sotagliflozin for kidney protection in type 1 diabetes
This study tests whether sotagliflozin (a pill that helps control blood sugar and protects the kidneys) can slow down kidney function decline in people with type 1 diabetes and diabetic kidney disease. You may qualify if you have had type 1 diabetes for at least 8 years, have moderate kidney damage, and are on standard treatments.
Boston, MassachusettsAges 18–75 - NCT04604418Recruiting
Tracking outcomes during non-heart procedures in children with heart defects
This study looks at how children with congenital heart disease do during routine non-heart procedures, including medical or minor treatments that are not heart-related. It also measures how much health care they use afterward, which may help improve care planning for families.
Boston, MassachusettsAges Up to 21 years - NCT03524222Recruiting
Home hospital care for adults after sudden illness
This trial tests whether certain adults can safely receive hospital-level care at home instead of staying in the hospital, using a home care team. It may help you recover in your own home if your condition fits their plan and you have support at home.
Boston, MassachusettsAges 18 years+ - NCT04299828Recruiting
Study of inflammation activity during complex heart surgery
This study measures how active white blood cells and inflammation are during complex heart surgery using a heart-lung machine. It may help doctors better understand what triggers inflammation during surgery and how to improve care.
Boston, MassachusettsAges Any age - NCT07525843Recruiting
Well-being education program for teens with heart disease
This study tests whether a special education program about managing emotions and stress helps teenagers with moderate-to-severe congenital heart disease (a heart condition from birth) feel better and cope with their condition. Participants attend sessions and complete surveys over time.
Boston, MassachusettsAges 12–17 - NCT06001814Recruiting
Mindfulness program for heart health in older adults with HIV
This study tests whether a mindfulness and behavior change program can help older adults with HIV improve their heart health. It combines phone-based coaching and text messages to reduce stress and manage heart risk factors like high blood pressure and diabetes.
Boston, MassachusettsAges 50 years+ - NCT02061436Recruiting
Chronic total occlusion procedure registry
This study collects data from patients who are having a procedure to open a completely blocked coronary artery. It may help improve future treatments for this condition.
Boston, MassachusettsAges Any age - NCT04451044Enrolling by invitation
Guided heart stent planning using an inside pressure sensor
This study tests whether using a tiny pressure sensor in heart arteries during a procedure can better guide where to place a stent. It may help doctors choose the safest and most effective stent plan by more accurately measuring artery narrowing.
Boston, MassachusettsAges 18 years+ - NCT06434207Recruiting
Heart defect study in newborns to understand blood clots
This study looks at tiny particles from cells in newborns with heart defects to understand blood clot risks. It aims to find ways to prevent clots after heart surgery.
Boston, MassachusettsAges 1 day–1 week - NCT06387446Recruiting
Donated heart valve transplant for children and young adults
This study is testing a new way to replace a damaged heart valve using a donated valve (allograft) that may last longer and work better for children and young adults. It may be a good option if you need a new valve and have few other choices.
Boston, MassachusettsAges 4 weeks–50 years - NCT05687292Recruiting
Decision tool to shorten breathing machine time in children
This study tests whether a computer “decision support” tool can help doctors safely reduce how long a child stays on a breathing machine after heart surgery. It may help children get off mechanical ventilation sooner and recover faster.
Boston, MassachusettsAges 1 day–12 years - NCT07466745Recruiting
New Pulmonary Valve Study for Kids Needing Replacement
This study tests a new type of replacement valve for children who need a new pulmonary valve (the valve between the heart and lungs). Researchers want to see if the valve works safely and well in real-world use.
Boston, MassachusettsAges 1.5 years–16 years - NCT05443321Enrolling by invitation
Health information sharing during hospital transfers
This trial studies whether sharing patients’ health information between hospitals during transfers can improve outcomes. You may be included if you are moved from a specific partner hospital to Brigham and Women’s Hospital and admitted to certain hospital units.
Boston, MassachusettsAges 18 years+ - NCT05918211RecruitingPhase 3
Udenafil test during exercise for teens with Fontan circulation
This trial tests whether udenafil helps teens and young people with Fontan circulation do better on exercise and breathing-related measures over time. You’d need to be on blood-thinning medicine, and be able to complete exercise testing safely.
Boston, MassachusettsAges 12–18 - NCT05610787Enrolling by invitation
Testing a device that helps move an EXCOR pediatric heart pump
This trial studies an “active driving” system that controls the EXCOR pediatric heart pump. It’s meant for children who need a heart pump as a bridge to heart transplantation, to help the pump work more safely and effectively.
Boston, MassachusettsAges Up to 21 years - NCT03142152Recruiting
Mitral valve implant for heart failure with leaky mitral valve
This trial tests whether a device called the Carillon Mitral Contour System can help people with heart failure caused by a mild-to-moderate leaky mitral valve. You’d be compared against a control group, and the goal is to improve heart failure symptoms and outcomes.
Boston, MassachusettsAges 18 years+ - NCT06526195Recruiting
A study of CardioMEMS and HeartMate 3 for advanced heart failure
This trial tests if a combination of a tiny lung-artery pressure sensor (CardioMEMS) and a mechanical heart pump (HeartMate 3) is safe and effective for people with advanced heart failure. If you qualify, you'll either get the heart pump plus standard medical therapy, or continue with standard therapy alone and have your pressure monitored remotely.
Boston, MassachusettsAges 18 years+ - NCT06563895RecruitingPhase 3
Testing acoramidis to prevent ATTR amyloidosis in gene carriers
This trial tests a daily pill called acoramidis to see if it can prevent ATTR amyloidosis in people who carry a gene mutation but have no symptoms yet. It aims to stop the disease before it starts.
Boston, MassachusettsAges 18–75 - NCT07114718Recruiting
Stent for babies with heart defect needing extra blood flow
This trial tests a special stent for babies with a heart defect that needs a temporary blood vessel to stay open. The stent is placed to help blood flow to the lungs until the baby can have a more permanent surgery.
Boston, MassachusettsAges 1 minute–6 months - NCT04735835Recruiting
Personalized diet testing using ZOE app and blood samples
This trial studies how different food compositions affect your body, using the ZOE testing program plus meals you eat and blood samples you collect. It may help you learn more about what foods work best for you, especially if you have a long-term health condition.
Needham, MassachusettsAges 18 years+ - NCT04124120Recruiting
Single vs multiple bypass grafts for women heart surgery
This study compares outcomes of using one bypass graft versus multiple bypass grafts during coronary artery bypass surgery in women. It aims to see which approach leads to better recovery and heart outcomes for eligible patients.
Worcester, MassachusettsAges 18 years+ - NCT07714252Enrolling by invitation
Virtual palliative care team for veterans with heart or lung disease
This study tests a virtual team of nurses and social workers who provide palliative care to veterans with heart failure, COPD, or interstitial lung disease. The goal is to improve quality of life by offering extra support at home.
Providence, Rhode IslandAges 18 years+
Hear when a new Heart Diseases trial opens near Boston, MA
We’ll email you when one opens near Boston, MA — at most once a week, no account needed, unsubscribe anytime.
Heart Diseases trials in other cities
Where these studies are running near Boston
Institutions with a site for the recruiting heart diseases studies listed above.
- Boston Children's Hospital · 10 studies
- Massachusetts General Hospital · 5 studies
- Brigham and Women's Hospital · 4 studies
- Beth Israel Deaconess
- Beth Israel Deaconess Medical Center
- Boston University (BU) School of Medicine
- Joslin Diabetes Center
- Mass General
What taking part in a heart diseases study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting heart diseases studies in Massachusetts.
Common questions
- Are there heart diseases clinical trials near Boston?
- Yes. We're currently tracking 46 recruiting heart diseases studies with a site near Boston, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a heart diseases study near Boston?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Boston to take part?
- Not necessarily. These studies have a site near Boston, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a heart diseases trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New heart diseases studies open near Boston regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.