Clinical trials · Los Angeles, CA
Heart Diseases clinical trials in Los Angeles
We’re tracking 41 recruiting heart diseases studies with a site in or near Los Angeles — including Early Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Los Angeles
- NCT07582848Recruiting
Breastfeeding Support for Babies with Heart Disease
This study helps mothers of babies born with heart defects learn to breastfeed directly, even when the baby needs heart surgery in the first month of life. Researchers want to see if direct breastfeeding improves health outcomes for both mother and baby during this critical time.
Los Angeles, CaliforniaAges 18 years+ - NCT06310031Recruiting
Testing BrioVAD heart pump for severe heart failure
This trial tests a new left-ventricular assist device (LVAD) called BrioVAD for people with advanced heart failure who are not getting enough benefit from medicines. If you qualify, the device is implanted to help your heart pump blood.
Los Angeles, CaliforniaAges 18–100 - NCT05427370Recruiting
Compare bypass or stent treatment in weak heart patients
This study compares two ways to restore blood flow to the heart—bypass surgery (CABG) or stent procedure (PCI)—in people with a weak pumping heart. It looks at which approach works best when the heart muscle is not pumping well and there are multiple blocked heart arteries.
Los Angeles, CaliforniaAges 18 years+ - NCT06326996RecruitingEarly Phase 1
Thiamine before bypass surgery
This study tests if giving thiamine (vitamin B1) before heart bypass surgery can help people with low thiamine levels. It is designed for patients who are having a specific type of bypass that does not use a heart-lung machine.
Los Angeles, CaliforniaAges 60–80 - NCT07466745Recruiting
New Pulmonary Valve Study for Kids Needing Replacement
This study tests a new type of replacement valve for children who need a new pulmonary valve (the valve between the heart and lungs). Researchers want to see if the valve works safely and well in real-world use.
Los Angeles, CaliforniaAges 1.5 years–16 years - NCT07023367Recruiting
Parent navigator program for Latino families of babies with heart disease
This study offers a parent navigator program to help Latino families whose baby had early heart surgery. The program aims to support both the child's recovery and the parents' well-being.
Los Angeles, CaliforniaAges birth+ - NCT05918211RecruitingPhase 3
Udenafil test during exercise for teens with Fontan circulation
This trial tests whether udenafil helps teens and young people with Fontan circulation do better on exercise and breathing-related measures over time. You’d need to be on blood-thinning medicine, and be able to complete exercise testing safely.
Los Angeles, CaliforniaAges 12–18 - NCT05610787Enrolling by invitation
Testing a device that helps move an EXCOR pediatric heart pump
This trial studies an “active driving” system that controls the EXCOR pediatric heart pump. It’s meant for children who need a heart pump as a bridge to heart transplantation, to help the pump work more safely and effectively.
Los Angeles, CaliforniaAges Up to 21 years - NCT03142152Recruiting
Mitral valve implant for heart failure with leaky mitral valve
This trial tests whether a device called the Carillon Mitral Contour System can help people with heart failure caused by a mild-to-moderate leaky mitral valve. You’d be compared against a control group, and the goal is to improve heart failure symptoms and outcomes.
Los Angeles, CaliforniaAges 18 years+ - NCT06563895RecruitingPhase 3
Testing acoramidis to prevent ATTR amyloidosis in gene carriers
This trial tests a daily pill called acoramidis to see if it can prevent ATTR amyloidosis in people who carry a gene mutation but have no symptoms yet. It aims to stop the disease before it starts.
Los Angeles, CaliforniaAges 18–75 - NCT06590467Recruiting
Abbott heart device registry study
This registry is a large, ongoing study that collects information about Abbott heart devices used in routine care. It helps doctors learn how well these devices work and how patients are doing over time, without changing your treatment plan.
Los Angeles, CaliforniaAges Any age - NCT06478017RecruitingPhase 2
Belatacept for heart transplant recipients
This study tests a drug called belatacept, which may help prevent the body from rejecting a new heart. It is given after a heart transplant, and the goal is to see if it works as well as or better than standard anti-rejection medicines.
Los Angeles, CaliforniaAges 18–76 - NCT07114718Recruiting
Stent for babies with heart defect needing extra blood flow
This trial tests a special stent for babies with a heart defect that needs a temporary blood vessel to stay open. The stent is placed to help blood flow to the lungs until the baby can have a more permanent surgery.
Los Angeles, CaliforniaAges 1 minute–6 months - NCT03954574Recruiting
Check blood flow changes in lungs during exercise testing
This study measures how blood moves through your lungs and heart while you exercise, using standard heart-lung pressure measurements. It may help doctors better understand unexplained breathing trouble or suspected pulmonary hypertension and improve how testing and care are guided.
Los Angeles, CaliforniaAges 18 years+ - NCT05867381Recruiting
Air purifier use to slow heart artery plaque in older adults
This trial tests whether using indoor air filtration at home can slow the progression of heart artery plaque-related problems in people with a past history of ischemic heart disease. It may help by improving indoor air quality, which the study links to inflammation in the body.
Los Angeles, CaliforniaAges 65–84 - NCT04843072Recruiting
Comparing two new valve options for a failing replacement aortic valve
This trial compares two types of replacement heart valves (balloon-expandable and self-expanding) for people whose prior surgical aortic valve is no longer working. It looks at which valve type offers better outcomes when placed through a catheter in the leg.
Los Angeles, CaliforniaAges 18 years+ - NCT07288216RecruitingPhase 2
Switching to KPL-387 alone for well-controlled pericarditis
This study tests whether a new drug, KPL-387, can keep your pericarditis under control as your only treatment, after you have been stable on other medicines. It is for people whose pericarditis is well controlled now but who have had flares in the past.
Los Angeles, CaliforniaAges 18–80 - NCT06927739RecruitingPhase 2
Orticumab for heart artery inflammation after a heart attack
This trial tests a drug called orticumab to see if it can reduce inflammation in the arteries of the heart after a heart attack. It may help prevent future heart problems.
Los Angeles, CaliforniaAges 18 years+ - NCT07582861Recruiting
Support for Mothers Expecting Babies With Heart Disease
This study offers psychological support to pregnant mothers who have learned their baby has congenital heart disease (a heart condition present at birth). The research tests whether counseling and coping strategies provided before and after birth can help mothers manage stress and anxiety during this challenging time.
Los Angeles, CaliforniaAges 18 years+ - NCT07797335RecruitingPhase 3
Zenagamtide for diabetes and weight loss
This study compares a new once-weekly injection to lower blood sugar levels against a standard daily injection in people with type 2 diabetes who are at high risk for heart problems. It aims to find out if the new medicine is more effective in managing blood sugar and body weight.
Los Angeles, CaliforniaAges 45 years+ - NCT00573027Recruiting
Study of heart pain from small artery heart disease
This trial studies people who have chest pain (angina) due to problems with the heart’s small arteries, not a big blockage. It aims to test whether treatment approaches can help these patients by better understanding the cause of their heart-related symptoms.
Los Angeles, CaliforniaAges 18 years+ - NCT02852031Recruiting
Care program for newborns needing the Norwood procedure
This trial focuses on improving care for babies born with certain complex heart conditions where only one pumping chamber works. It is meant for babies (including unborn babies) who are planned to have the Norwood procedure, which is a common early surgery.
Los Angeles, CaliforniaAges Up to 1.3 years - NCT04124120Recruiting
Single vs multiple bypass grafts for women heart surgery
This study compares outcomes of using one bypass graft versus multiple bypass grafts during coronary artery bypass surgery in women. It aims to see which approach leads to better recovery and heart outcomes for eligible patients.
Los Angeles, CaliforniaAges 18 years+ - NCT07130994Recruiting
Testing a new less invasive mitral valve replacement (SATURN)
This trial tests a new, less invasive device called the SATURN system to replace a severely leaky mitral heart valve without open-heart surgery. It is for people who are too high-risk for traditional surgery and are willing to take blood thinners.
Los Angeles, CaliforniaAges 18 years+
Hear when a new Heart Diseases trial opens near Los Angeles, CA
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Heart Diseases trials in other cities
Where these studies are running near Los Angeles
Institutions with a site for the recruiting heart diseases studies listed above.
- Cedars-Sinai Medical Center · 6 studies
- Children's Hospital of Los Angeles · 4 studies
- Children's Hospital Los Angeles · 3 studies
- Keck School of Medicine of USC · 2 studies
- University of California, Los Angeles (UCLA) · 2 studies
- Abcentra Investigational Site
- Cedars-Sinai Women's Heart Center
- First Valley Medical Group
What taking part in a heart diseases study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting heart diseases studies in California.
Common questions
- Are there heart diseases clinical trials near Los Angeles?
- Yes. We're currently tracking 41 recruiting heart diseases studies with a site near Los Angeles, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a heart diseases study near Los Angeles?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Los Angeles to take part?
- Not necessarily. These studies have a site near Los Angeles, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a heart diseases trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New heart diseases studies open near Los Angeles regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.