Clinical trials · Florida
Heart Failure With Preserved Ejection Fraction clinical trials in Florida
We’re tracking 16 recruiting heart failure with preserved ejection fraction studies with a site in Florida — including Early Phase 1, Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Florida
- NCT07830758RecruitingPhase 1
Resmetirom for fatty liver disease with heart failure
This trial tests a drug called resmetirom for people who have both a type of fatty liver disease (MASH) and a type of heart failure (HFpEF). It aims to see if the drug can help both conditions. You may be able to join if you have both conditions and meet certain health criteria.
Fort Myers, FloridaAges 18 years+ - NCT07795814RecruitingPhase 2
Study of a new medicine for heart failure with preserved pumping function
This study tests an investigational medicine called EDG-15400 for people with a type of heart failure where the heart muscle is stiff and doesn't relax properly, even though the pumping function is normal. The goal is to see if the medicine improves symptoms and daily functioning.
Gainesville, FloridaAges 30–84 - NCT07761117RecruitingPhase 3
Heart failure treatment study for people with preserved pumping function
This study tests an investigational medication called elecoglipron to see if it can improve heart and blood vessel outcomes in people with heart failure with preserved or mildly reduced ejection fraction. If you join, you will receive either the study drug or a placebo, and your heart health will be monitored over time.
Ocoee, FloridaAges 18 years+ - NCT02901184RecruitingPhase 3
Spironolactone start study for heart failure with preserved pumping
This trial tests whether starting spironolactone helps people with heart failure symptoms when the heart pumps “preserved” (not severely reduced). Participants are assigned to start spironolactone or usual care so researchers can see if it improves outcomes.
Fort Lauderdale, FloridaAges 50–99 - NCT07634640RecruitingEarly Phase 1
Testing an Inflammation Treatment for Heart Failure
This early-stage trial tests a new approach to treat heart failure with preserved ejection fraction (HFpEF)—a type of heart failure where the heart's pumping strength is normal, but it doesn't relax properly. Researchers believe inflammation plays a role and want to see if targeting it can help patients feel better and function more easily.
Gainesville, FloridaAges 18–85 - NCT07219511RecruitingPhase 1
Safety study of VS-041 for heart failure with preserved pumping strength
This trial tests an investigational drug called VS-041 to see if it's safe and helps people with a type of heart failure where the heart pumps well but doesn't relax properly (HFpEF). It may be an option if you are 50 or older and have stable heart failure symptoms.
Hialeah, FloridaAges 50 years+ - NCT07214376Recruiting
Nerve ablation for pulmonary hypertension from left heart disease
This trial tests a device that uses a catheter to deliver energy to nerves around the pulmonary arteries, aiming to reduce high blood pressure in the lungs caused by left heart failure. It is for people with ongoing heart failure symptoms despite optimal medications.
Weston, FloridaAges 18–85 - NCT07037459RecruitingPhase 3
A study of a new drug for heart failure with obesity
This trial tests a medication called maridebart cafraglutide for people with heart failure (where the heart doesn't pump as well as it should) and obesity. The goal is to see if it can help improve symptoms and outcomes.
Altamonte Springs, FloridaAges 18–99 - NCT06979362RecruitingPhase 2
Testing a new medicine for heart failure with thickened heart muscle
This study tests an experimental medicine, CDR132L, to see if it can improve heart structure and function in people with a type of heart failure where the heart muscle is thickened. If you have heart failure with normal pumping function and thickened heart walls, this trial may offer access to a new potential treatment.
Miami Lakes, FloridaAges 40–84 - NCT06793371RecruitingPhase 2
Study of CK-4021586 for heart failure with preserved ejection fraction
This trial tests an investigational drug called CK-4021586 for people with heart failure with preserved ejection fraction (HFpEF). It aims to see if the drug is safe and well-tolerated. You may qualify if you are 40 to 85, have heart failure symptoms, and have a heart that pumps well but shows signs of strain.
Hialeah, FloridaAges 40–85 - NCT06763549Enrolling by invitation
AI-powered wearable patch for heart and lung monitoring
This study tests an AI-powered wearable patch (the COR ECG) to see if it can better track heart and lung health. It may help doctors find problems earlier without needing bulky equipment.
Melbourne, FloridaAges 18 years+ - NCT06678841Recruiting
Pacing therapy for heart failure with preserved pumping ability
This study tests a new pacing approach for people with a specific type of heart failure (HFpEF) to see if it can improve symptoms and quality of life. It involves a pacemaker-like device that adjusts heart rate based on your needs.
Panama City, FloridaAges 40 years+ - NCT05839067Recruiting
Support program for U.S. veterans living with heart failure
This trial supports U.S. Veterans who have heart failure, to see whether the added support improves health and well-being. You may be able to join if you meet the age, diagnosis, and communication requirements.
Gainesville, FloridaAges 18 years+ - NCT06008197RecruitingPhase 3
A study of finerenone for hospitalized heart failure patients
This trial tests a medication called finerenone to see if it helps people hospitalized for heart failure live longer and have fewer heart-related problems. It may be an option for those with a certain type of heart failure where the heart's pumping strength is mildly reduced or normal.
Bradenton, FloridaAges 18 years+ - NCT05064709Recruiting
Test device for heart failure symptoms in some patients
This study tests whether a heart-related device called CCM can improve symptoms and daily function in people with heart failure and a moderately reduced pumping strength. It may help if you’ve had recent heart-failure-related hospital care or urgent treatment and your heart and overall health fit the study limits.
Miami, FloridaAges 18 years+ - NCT03876223Recruiting
Testing imaging to study heart symptoms without blocked arteries
This trial studies people who have heart-related symptoms but do not have clear blocked heart arteries, using special heart imaging. It may help researchers better understand early forms of heart weakness (with preserved pumping function) and improve how these conditions are diagnosed.
Gainesville, FloridaAges 18 years+
Heart Failure With Preserved Ejection Fraction trials by city in Florida
Where these studies are running in Florida
Institutions with a site for the recruiting heart failure with preserved ejection fraction studies listed above.
- AdventHealth Orlando · 3 studies
- Broward Research Center · 2 studies
- Cleveland Clinic Florida · 2 studies
- Jacksonville Center for Clinical Research · 2 studies
- New Generation of Medical Research · 2 studies
- University of Florida · 2 studies
- Amavita Health
- Ascension Sacred Heart
What taking part in a heart failure with preserved ejection fraction study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Heart Failure With Preserved Ejection Fraction trials in other states
Common questions
- Are there heart failure with preserved ejection fraction clinical trials in Florida?
- Yes. We're currently tracking 16 recruiting heart failure with preserved ejection fraction studies with a site in Florida, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a heart failure with preserved ejection fraction study in Florida?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Florida to take part?
- Not necessarily. These studies have a site in Florida, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a heart failure with preserved ejection fraction trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New heart failure with preserved ejection fraction studies open in Florida regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.