Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 981 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07234422RecruitingPhase 3
Selenium and CoQ10 for heart failure
This study tests whether adding selenium and CoQ10 (two natural supplements) to standard heart failure treatment helps people with chronic heart failure feel better and improve their health. Researchers are using a registry-based approach to track participants in the Netherlands.
AlkmaarAges 18 years+ - NCT04066127Enrolling by invitation
Heart transplant study comparing two types of heart storage
This trial tests whether using a different method to store a donated heart before transplant improves outcomes. It compares “non-ischemic preservation” versus standard cold storage for people getting a new heart.
Lund, Skåne CountyAges 18 years+ - NCT07741305Recruiting
Comparing heart ultrasound imaging methods for heart failure
This study tests whether a 3D ultrasound of the heart gives better information than a standard 2D ultrasound in people with heart failure. It aims to improve how doctors measure heart function, which could help guide treatment.
Bari, BAAges 18 years+ - NCT07123779RecruitingPhase 1/Phase 2
Study of HS235 in obese patients with pulmonary hypertension and heart failure
This trial tests an investigational drug called HS235 in people who have both obesity (BMI 30-50) and a specific type of heart failure with preserved pumping function, along with high blood pressure in the lungs. The goal is to see if the drug can improve symptoms and quality of life.
Greenville, South CarolinaAges 18 years+ - NCT05383287Recruiting
Study of heart failure with preserved pumping function
This study looks at the different features and patterns of people with heart failure where the heart’s pumping strength is preserved. It may help doctors better understand your type of heart failure and tailor care.
ManchesterAges 18 years+ - NCT05089162Recruiting
Testing a heart ultrasound approach in chronic heart failure
This study looks at people with chronic heart failure with weaker pumping function and checks how well a lung/heart ultrasound can assess congestion (fluid buildup). If you qualify, you may help test a better way to evaluate your condition during a planned hospital visit.
Vandœuvre-lès-NancyAges 18 years+ - NCT06377761Recruiting
Qishen granules for heart failure with preserved pumping function
This trial tests a Chinese herbal medicine called Qishen Granules for people with heart failure who still have a normal pumping ability (ejection fraction 50% or higher). It may help reduce symptoms and improve heart function.
Guangzhou, GuangdongAges 18–85 - NCT05097898Recruiting
Check fluid buildup in heart failure with normal pumping
This study evaluates how well doctors can assess “fluid congestion” in people with chronic heart failure where the heart’s squeezing is still preserved. It may help improve how patients are monitored during hospital visits.
Vandœuvre-lès-NancyAges 18 years+ - NCT06706791RecruitingPhase 4
Empagliflozin for heart failure & diabetes: quality of life study
This trial tests whether a diabetes medicine called empagliflozin can improve the quality of life for people who have both chronic heart failure with a weak heart pump and type 2 diabetes. It compares the effects of adding empagliflozin to your current treatments.
Karachi, SindhAges 40–70 - NCT05507879Recruiting
Breast cancer heart monitoring to predict heart damage risk
This trial studies how a blood test marker (TRPC6) may help predict and prevent heart muscle damage and heart failure related to some breast cancer medicines. You may join if you’re starting or have received treatment that can stress the heart, or if you already have signs of treatment-related heart problems.
Gainesville, FloridaAges 18 years+ - NCT07067658Recruiting
Monitoring leg swelling in heart failure to reduce hospital stays
This trial tests a new home monitoring device for people with heart failure and leg swelling. The device helps track fluid changes early, so you may be able to avoid hospital stays.
Aylesbury, BuckinghamshireAges 18 years+ - NCT04899479RecruitingPhase 4
SGLT-2 inhibitor after heart attack to improve heart recovery
This trial studies whether starting an SGLT-2 inhibitor around the time of a heart attack can reduce heart damage size and improve how the heart heals. It focuses on people with a high risk of developing heart failure and who are getting a procedure to open blocked heart arteries.
SeoulAges 18 years+ - NCT05583773RecruitingPhase 4
Herbal medicine for heart failure with lower pumping strength
This trial tests SHengXIaN-QuYu decoction (an herbal treatment) in people with symptomatic heart failure and reduced pumping function. It looks to see whether the herbal formula is safe and helpful for heart failure symptoms and heart function.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06105580Recruiting
Pacing methods for heart failure with wide QRS
This trial compares two ways to pace the heart in people with heart failure and a wide QRS (a sign the heart's electrical signals are slowed). The goal is to see which method better reduces the risks of death, heart failure hospitalization, or needing a heart transplant.
BarcelonaAges 18 years+ - NCT06154044RecruitingPhase 2
Cell therapy for heart recovery with LVAD support
This trial tests whether injecting special cells (cell therapy) can help the heart recover in people with advanced heart failure who are getting a mechanical heart pump (LVAD). It may offer a new way to improve heart function and quality of life.
LjubljanaAges 18–65 - NCT06447467Recruiting
Heart failure recovery in diabetics and non-diabetics
This study looks at how people with and without diabetes recover from acute heart failure (a sudden worsening). It aims to compare short-term outcomes in the hospital.
SohagAges 18 years+ - NCT06540521Recruiting
Heart device holter study for LBBAP patients
This study uses a special wearable device to record your heart's electrical signals. It is for people who have a pacemaker or CRT-P with a specific type of lead (LBBAP) and wants to check how well the therapy is working.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06593314Recruiting
Using heart ultrasound to find and treat heart failure risk in diabetes
This trial tests a special software (Ultromics EchoGo) that looks at your heart ultrasound to find people with type 2 diabetes who are at high risk for heart failure. If you're at risk, the software helps your doctor decide on treatments to prevent heart failure.
Dallas, TexasAges Any age - NCT06183437RecruitingPhase 4
Can I stop heart meds after cancer therapy?
This trial tests whether it is safe to stop taking heart failure medications in people who developed heart weakness after cancer treatment but whose heart function has since recovered. It aims to see if stopping these drugs leads to any worsening of heart health.
Los Angeles, CaliforniaAges 18 years+ - NCT07184541Recruiting
Nurse-led weight monitoring for heart failure quality of life
This study tests a nurse-led program where you weigh yourself daily at home to help manage your heart failure. It aims to improve your quality of life and your ability to care for yourself.
Avon, OhioAges 55 years+ - NCT06704633RecruitingPhase 4
Heart failure drug study for rural Tanzanians
This trial tests a medicine called sacubitril-valsartan for people in rural Tanzania with heart failure and reduced pumping strength. It aims to see if switching to this drug can improve symptoms and outcomes.
Ifakara, MorogoroAges 18 years+ - NCT07460219Enrolling by invitation
Pharmacist-led heart failure medication study for VA clinics
This trial tests if pharmacists in VA regions can help adjust heart failure medications. It may improve how patients are treated.
Palo Alto, CaliforniaAges 18 years+ - NCT07556185Recruiting
Testing a home heart health monitoring app for kids
This study tests whether young people with heart conditions can use a home monitoring app called Medly to track their symptoms and weight. The app may help doctors catch problems earlier and keep kids healthier at home.
Toronto, OntarioAges 8–18 - NCT06080074RecruitingPhase 2
Emergency heart-lung machine study for children with severe heart failure
This study tests a specific heart-lung machine called Cardiohelp to help children with severe heart failure. It looks at how well the machine works and whether a blood thinner (either heparin or bivalirudin) is safer and more effective.
Palo Alto, CaliforniaAges birth–16 years
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Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 981 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.