Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 949 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07685106Recruiting
Cardiostory device test for heart failure in shortness of breath
This trial tests if a device called Cardiostory can tell if your shortness of breath (dyspnea) is caused by heart failure or something else. It's for people who started having trouble breathing in the last week.
Monastir, Monastir GovernorateAges 18 years+ - NCT07449377Recruiting
Can a liver scan help diagnose heart failure in the ER?
This study tests whether a quick, non-invasive liver scan (Fibroscan) can help diagnose heart failure in people who come to the emergency department with sudden shortness of breath.
ParisAges 18 years+ - NCT07435662Recruiting
Improving heart failure care in Denver
This study aims to improve heart failure treatment for people who have limited access to care in Denver. If you have heart failure with reduced pumping ability and are a patient in the Denver Health system, this trial may help find better ways to manage your condition.
Denver, ColoradoAges 18 years+ - NCT07275931Recruiting
Digital support program for heart failure patients
Researchers in Sweden are testing a digital support program to help patients with heart failure manage their condition at home. If you qualify, you'll use a smartphone or computer-based program that may offer tips, tracking, and help from a care team.
Linköping, Östergötland CountyAges 18 years+ - NCT07100561Recruiting
Heart Failure Re-Admission Study
This trial will follow people with heart failure who are admitted to the hospital to see who returns within 30 and 90 days. It aims to understand how to reduce future hospital visits.
Kumasi, Ashanti RegionAges 18 years+ - NCT07094425Recruiting
Heart function study for ICU patients on breathing machines
This study looks at how the heart is affected in critically ill patients who need a breathing machine. It uses ultrasound and other simple tests to check for heart problems that can happen in the ICU, which may help doctors find and treat them earlier.
Vienna, State of ViennaAges 18 years+ - NCT06920160Recruiting
Remote monitoring for heart failure with reduced ejection fraction
This trial tests whether a smartphone app can help monitor your heart health after a hospital stay for heart failure. It is for people who use a smartphone often and have a type of heart failure where the heart's pumping strength is lower than normal.
Ferrol, A CoruñaAges 18 years+ - NCT06435156RecruitingPhase 2
Sotagliflozin for Heart Failure in Type 1 Diabetes
This trial tests a medication called sotagliflozin for people who have both type 1 diabetes and heart failure symptoms. The goal is to see if it can improve how you feel and manage your heart and diabetes.
AberdeenAges 18–84 - NCT07556588Recruiting
Heart transplant study using perfusion technology
This study tests a special machine that helps preserve and evaluate donor hearts before transplant. If you're waiting for a heart transplant, this trial may help doctors find the best donor hearts and improve transplant outcomes.
LeuvenAges 18 years+ - NCT07318103RecruitingPhase 2
Study of HRS-9057 for fluid retention in heart failure
This trial tests an investigational drug, HRS-9057, in people hospitalized with heart failure who still have fluid buildup despite taking standard diuretics. The goal is to see if HRS-9057 helps remove excess fluid better than current treatments.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07192952RecruitingPhase 3
Long-term safety of finerenone for children with heart failure
This trial tests a medicine called finerenone to see if it is safe for children and young adults with heart failure when taken for a long time. It may help improve heart function and manage symptoms.
Aurora, ColoradoAges Up to 18 years - NCT07188805RecruitingPhase 3
Finerenone for children with heart failure
This study tests a medicine called finerenone in children with heart failure. It looks at whether finerenone helps the heart work better and is safe compared to a placebo (a dummy pill), when taken with the usual heart-failure medicines.
Aurora, ColoradoAges 6 months–17 years - NCT07711821Recruiting
Heart failure screening in primary care for older adults
This trial is testing a simple screening tool to find early signs of heart failure in people aged 50 or older, especially those with risk factors like diabetes or high blood pressure. If you're at risk, this could help catch heart problems sooner.
AmadoraAges 49 years+ - NCT06652087Recruiting
Testing rifaximin for heart failure with preserved pumping
This trial tests whether the antibiotic rifaximin (taken by mouth) can improve heart function in people with a type of heart failure where the heart pumps well but is still weak (HFpEF). Rifaximin might help by changing the bacteria in your gut.
MoscowAges 18–80 - NCT06249932RecruitingPhase 4
Empagliflozin for heart failure and end-stage kidney disease
This trial tests whether empagliflozin, a medication for heart failure, can help people who also have end-stage kidney disease and are on dialysis. It aims to see if the drug improves heart function in this group.
Hsinchu, TaiwanAges 20 years+ - NCT06249945RecruitingPhase 4
Empagliflozin for heart failure with preserved ejection fraction and dialysis
This trial tests whether a medicine called empagliflozin (used for diabetes and heart failure) can help people with both heart failure (with preserved pumping ability) and end-stage kidney disease who are on dialysis. The study looks at how the drug affects heart function and overall well-being.
HsinchuAges 20 years+ - NCT07319039Recruiting
Brain scan study of breathlessness in cancer, COPD, and heart failure
This study uses a brain scan (fMRI) to learn how the brain processes shortness of breath in people with advanced heart failure, COPD, or lung cancer. It aims to help doctors better understand and treat breathlessness.
Geneva, Canton of GenevaAges 18 years+ - NCT07281859Recruiting
Heart monitor alert study for new ICD patients
This study tests a heart failure alert system called HeartInsight in people who recently received an ICD or CRT-D device. The goal is to see if the alerts help doctors manage care better. You may qualify if you got a new (not replacement) device less than a year ago.
Mercogliano, AvellinoAges 18 years+ - NCT06677060RecruitingPhase 3
Study of baxdrostat plus dapagliflozin for heart risk in type 2 diabetes
This study tests whether a new drug called baxdrostat, when added to the diabetes medicine dapagliflozin (Farxiga), can prevent heart failure and heart-related death in people with type 2 diabetes, high blood pressure, and existing heart or blood vessel disease. You may be able to join if you have type 2 diabetes, heart or blood vessel disease, high blood pressure, and at least one extra risk factor for heart failure.
Birmingham, AlabamaAges 40 years+ - NCT06118983Recruiting
Improving care transitions for heart failure patients in home health
This trial tests a program called I-TRANSFER-HF to improve how heart failure patients move from hospital to home with home health care. It aims to help you have a smoother recovery and avoid coming back to the hospital.
New York, New YorkAges 18 years+ - NCT05714085RecruitingPhase 2/Phase 3
Vericiguat study for children with heart failure
This trial tests whether vericiguat helps children with chronic heart failure caused by weaker left heart pumping. It also checks safety and how the medicine behaves in the body (dose and processing).
Los Angeles, CaliforniaAges 4 weeks–17 years - NCT05194111RecruitingPhase 1/Phase 2
Heart medication study for cancer survivors with mild heart weakness
This study tests a heart medication (sacubitril/valsartan) in young cancer survivors whose hearts were weakened by anthracycline chemotherapy but are not yet having heart failure symptoms. It aims to see if the drug can improve heart function and prevent future problems.
Richmond, VirginiaAges 18–120 - NCT06243653Recruiting
Heart microvessel function test for heart failure recovery
This trial looks at how tiny blood vessels in the heart affect improvement in heart pumping strength for people with heart failure. It tests whether a special procedure during heart catheterization can predict recovery.
SeoulAges 19 years+ - NCT06342492Recruiting
Comparing two pacing methods for lead failure in heart failure
This study compares two ways to fix a failed lead in a heart failure pacemaker: placing a new lead on the outside of the heart or using the heart's own electrical system. It follows people whose CRT lead stopped working and was replaced, to see which method works best.
Overland Park, KansasAges 18 years+
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Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 949 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.