Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 949 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07391683Recruiting
Heart failure support before heart surgery
This trial tests if special remote care before heart surgery can improve recovery for people with heart failure. You will have regular check-ins by video or phone to help manage your health before your operation.
Innsbruck, TyrolAges 18 years+ - NCT07320677Enrolling by invitation
Finding Heart Failure in People Taking Water Pills
This study is for people who take a type of water pill called a loop diuretic, but do not yet have a diagnosis of heart failure. The study will check a blood test to see if undiagnosed heart failure might be present.
Saint HelierAges 18 years+ - NCT06435585Recruiting
Heart failure genetics and response study
This study looks at how genes affect heart failure treatment response. It uses blood samples to find new markers that may help predict who will benefit most from therapy.
StockholmAges 18 years+ - NCT06360380Recruiting
Wearable device for fluid removal in heart failure
This trial tests a wearable device that removes extra fluid from your body without using the kidneys. It may help people with heart failure who still have fluid buildup despite taking high doses of water pills.
La Jolla, CaliforniaAges 21–79 - NCT05411614Recruiting
Testing two heart procedures for atrial fibrillation in heart failure
This study compares two different ablation procedures (treatments that target heart rhythm triggers) for people with atrial fibrillation and reduced heart pumping. It aims to see which approach works best and is safest for improving your heart rhythm when you also have heart failure.
ChertseyAges 18 years+ - NCT04941794Recruiting
Test heart-related blood markers in people with type 2 diabetes
This study looks at blood tests (called biomarkers) to see if they can help predict chronic heart failure risk. It focuses on adults with type 2 diabetes over age 50 who do not already have certain heart conditions.
HjørringAges 50 years+ - NCT07490067RecruitingPhase 4
Metoprolol for heart failure: genes and drug response
This trial tests how the drug metoprolol works in people with heart failure and reduced pumping function. It looks at whether your genetic makeup affects how the drug is processed and how well it helps your heart.
Ann Arbor, MichiganAges 18 years+ - NCT06702501Recruiting
Shunt device to treat heart failure with preserved ejection fraction
This trial tests a tiny tube (shunt) placed in the heart to relieve pressure and ease severe shortness of breath. It's for people with a type of heart failure where the heart pumps well but doesn't relax enough.
Rochester, MinnesotaAges 30 years+ - NCT06148935Recruiting
Study of vericiguat in Korean heart failure patients
This study looks at how well Verquvo (vericiguat) works in daily life for Korean adults with chronic heart failure and a weak heart pump. It’s for people whose heart failure has recently gotten worse and who are starting Verquvo for the first time.
Multiple LocationsAges 19 years+ - NCT05666518Recruiting
Study of vericiguat safety in Japanese chronic heart failure patients
This study checks how safe the medicine vericiguat is for Japanese people with chronic heart failure when used in everyday care. It compares patients who receive vericiguat with patients who continue standard treatments without vericiguat.
Multiple Locations, Many LocationsAges Any age - NCT04583800Recruiting
Tracking heart failure risk and memory change in diabetes
This study follows adults with type 2 diabetes to see who may develop heart problems and who may have memory or thinking changes over time. It may help doctors better predict risk and plan earlier support.
LilleAges 18 years+ - NCT07081711Recruiting
Testing new heart MRI technology in volunteers
This study is testing a new way to take pictures of the heart using MRI. It is looking for healthy volunteers to help make sure the technology works correctly.
Cleveland, OhioAges 18 years+ - NCT05654272Recruiting
Testing CIRC imaging technology for people with heart problems
This study is developing and testing CIRC technologies using heart imaging. You may be able to join if you’re an adult with cardiovascular (heart) disease and can safely have the MRI scans.
Cleveland, OhioAges 18 years+ - NCT06906432Recruiting
Brain-Heart Injury After Brain Bleed Study
This study looks at how a brain bleed can affect the heart. Researchers hope to understand the link between brain and heart injury to help improve care for people who have had a brain bleed.
Beijing, Beijing MunicipalityAges 18–80 - NCT07154355Recruiting
Community exercise for heart and lung patients
This study tests whether a community exercise program can improve health in people with heart or lung problems. It may help if you are not already doing regular, structured exercise.
Guangzhou, GuangdongAges 18–85 - NCT07486791Recruiting
Baduanjin exercise for heart health after heart attack
This study tests whether a gentle exercise called 'Lying-Sitting-Standing' Baduanjin can improve heart and lung function and quality of life in people who have had a heart attack and also have heart failure.
Taiyuan, ShanxiAges Up to 85 years - NCT07352891Recruiting
Digital remote management vs. usual care for heart failure
This trial tests whether using a remote monitoring platform to help manage medications improves outcomes in people with heart failure and reduced pumping function. It compares this approach to standard follow-up care.
BeijingAges 18 years+ - NCT06678841Recruiting
Pacing therapy for heart failure with preserved pumping ability
This study tests a new pacing approach for people with a specific type of heart failure (HFpEF) to see if it can improve symptoms and quality of life. It involves a pacemaker-like device that adjusts heart rate based on your needs.
Phoenix, ArizonaAges 40 years+ - NCT05838287RecruitingPhase 4
Pioglitazone for heart failure with preserved pumping in type 2 diabetes
This trial tests whether pioglitazone (a diabetes medicine) helps people who have type 2 diabetes and a specific type of heart failure where the heart pumps normally. It may improve heart failure symptoms and function in carefully selected patients.
San Antonio, TexasAges 30–70 - NCT07224906Recruiting
Observing patients having a right heart catheterization
This study observes people who are already scheduled for a right heart catheterization, a procedure that checks the pressure in your heart. It helps doctors learn more about heart conditions without adding any extra treatments or procedures.
Boulder, ColoradoAges 18 years+ - NCT07076329Recruiting
Using a special diet to prevent malnutrition in older heart patients
This trial tests whether a special type of food can help prevent malnutrition in older adults with heart failure or atrial fibrillation. It looks at how the bacteria in your gut and inflammation in your body affect your brain and overall health.
FlorenceAges 70 years+ - NCT06898515Recruiting
Fluid removal study for acute heart failure patients
This trial tests a device designed to safely remove extra fluid from patients hospitalized with worsening heart failure. It may help those who are not responding well to standard water pills (diuretics).
Irvine, CaliforniaAges 22 years+ - NCT06033950RecruitingPhase 3
A study of finerenone for heart failure patients who can't take standard MRA drugs
This study tests whether finerenone, a new type of drug, can help people with heart failure who cannot take standard steroid-based MRAs (a kind of heart medication) because of side effects or other reasons. It aims to see if it improves symptoms and is safe for you.
Fairhope, AlabamaAges 18 years+ - NCT07814118Enrolling by invitation
Understanding how your body works during routine care
This study looks at how different body systems work together in people with various conditions and healthy volunteers. It uses routine medical tests and data to understand health better, which can help improve future care.
New York, New YorkAges 18 years+
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Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 949 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.