Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 981 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06461962Recruiting
Peer support for meth-related heart screening
This study tests whether a peer support program can help people who use methamphetamine get screened for early heart damage. It aims to connect you with care if screening shows possible heart strain.
Portland, OregonAges 18 years+ - NCT07465653RecruitingPhase 1
Study of HJB647 for heart failure with reduced pumping ability
This trial tests a new medicine, HJB647, in people with heart failure who have a weak heart pump. It aims to see if the drug is safe and well-tolerated. You may qualify if your heart's pumping ability is reduced and you are on a specific standard therapy.
Bradenton, FloridaAges 18–100 - NCT06862908RecruitingPhase 2
Study of IBI362 for heart failure with obesity
This study tests a new medicine called IBI362 for people with heart failure and obesity. The medicine may help improve symptoms and quality of life. You must have a specific type of heart failure (HFpEF or HFmrEF) and a BMI of 28 or higher.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07234565Recruiting
Improving social frailty through interactive learning
This trial tests a social program delivered over WeChat to help older adults with heart failure who feel socially frail. It aims to improve social connections and reduce frailty through interactive learning.
ShanghaiAges 60 years+ - NCT07281040Recruiting
Online discussion about heart failure treatment experiences
This study brings together people who have recently been in the hospital for heart failure and their caregivers to talk in small online groups about their experiences. The goal is to help doctors learn what matters most to patients and to plan better research on heart failure treatments.
Hull, YorkshireAges 18 years+ - NCT07420088Recruiting
Seasonal activity in heart failure with a heart device
This trial studies how physical activity changes with the seasons in people with heart failure who have a pacemaker or defibrillator. It aims to help doctors understand how to better support your activity levels throughout the year.
ÇorumAges 18 years+ - NCT07365501Enrolling by invitation
Blood pressure cuff therapy for heart failure patients
This trial tests if a simple, non-invasive blood pressure cuff procedure can improve blood vessel health in people with possible heart failure. It is an early, single-session study to see how the body responds.
Cuenca, CuencaAges 18 years+ - NCT06174103Recruiting
BiVACOR total artificial heart early feasibility study
This study tests a new total artificial heart called BiVACOR for people with severe heart failure that cannot be helped by standard pumps. It is designed to keep you alive while you wait for a heart transplant.
Phoenix, ArizonaAges 18–70 - NCT07057466Recruiting
AI heart check for hidden valve, pressure, or pump problems
This study uses an artificial intelligence (AI) program to read your ECG (a heart tracing) and detect early signs of heart failure, high blood pressure in the lungs, or valve disease before you have symptoms. The goal is to see if AI can catch these problems early.
BristolAges 18–90 - NCT06465498Recruiting
Lung ultrasound for heart failure congestion treatment
This trial tests whether using lung ultrasound to guide decongestion treatment improves outcomes for patients hospitalized with congestive heart failure. It may help doctors tailor your care more precisely.
Geneva, Canton of GenevaAges 18 years+ - NCT06337812Recruiting
Fiber supplement study for heart failure and diabetes
This study tests whether adding a daily fiber supplement can improve health in people with heart failure and type 2 diabetes. Participants take the supplement for several weeks to see if it helps manage symptoms and blood sugar.
Ann Arbor, MichiganAges 18 years+ - NCT07265349RecruitingPhase 1/Phase 2
Stem cells plus bypass surgery for chronic heart failure
This trial tests whether injecting stem cells from umbilical cord tissue into the heart muscle during bypass surgery can improve heart function in people with chronic heart failure. It is for patients who are already scheduled for bypass surgery and have a weakened heart pump (LVEF between 21% and 40%).
Shanghai, Shanghai MunicipalityAges 18–80 - NCT05508035RecruitingPhase 3
Testing sacubitril/valsartan vs ramipril for heart failure
This trial compares two blood-pressure and heart-failure medicines: sacubitril/valsartan versus ramipril, to see which improves heart pumping and heart structure over time. It’s aimed at people with ischemic (blocked-artery) heart failure with mid-range ejection fraction and ongoing symptoms.
Krakow, Lesser Poland VoivodeshipAges 18 years+ - NCT07113223Recruiting
AI heart test for heart failure detection in people over 65
This trial uses an artificial intelligence system to analyze electrocardiograms (ECGs, which are recordings of your heart's electrical activity) to detect heart failure early. It is for people over 65 who either have symptoms that might be heart failure or have risk factors for heart failure but no current symptoms.
MadridAges 65 years+ - NCT06244953Recruiting
Heart failure support program with palliative care
This study tests whether a tailored program that includes palliative care (extra support for comfort and quality of life) can help people with advanced heart failure and their family caregivers. It aims to reduce hospital visits and improve well-being.
SingaporeAges 21–99 - NCT05056129Recruiting
Phone game to help you manage heart failure
This trial tests whether a sensor-connected digital game (played on a phone) can help people manage heart failure day-to-day. It’s for adults who recently needed hospitalization and are able to do light activity and use a phone.
Austin, TexasAges 45 years+ - NCT06518694RecruitingPhase 3
Can you stop beta-blockers after heart failure recovery?
This trial tests whether people whose heart function has returned to normal after heart failure can safely stop taking beta-blockers. It aims to see if staying on the medication is still needed or if stopping is just as safe.
Paris, IDFAges 18 years+ - NCT06964464RecruitingPhase 4
Comparing two heart failure medications in ICD patients
This trial compares two beta-blocker medications, carvedilol and metoprolol succinate, to see which one works better for people with heart failure who have an implantable cardioverter defibrillator (ICD). If you are currently taking metoprolol succinate, you may be able to switch to carvedilol and help researchers find the best treatment.
Scottsdale, ArizonaAges 18 years+ - NCT07174362Recruiting
Heart failure study for newly diagnosed patients
This study is tracking people who were recently diagnosed with heart failure and have a weakened heart pumping function (less than 50%). It aims to learn more about the condition and improve care.
Basildon, EssexAges 18 years+ - NCT07309523Recruiting
Heart muscle strength in heart failure and diabetes
This study looks at how heart muscle strength changes in people with heart failure and/or diabetes. Researchers will use a pacemaker to safely measure tiny changes in heart function.
Leeds, West YorkshireAges 18 years+ - NCT07539766Recruiting
Obesity Surgery Study to Prevent Heart Problems
This study follows people with obesity who are having weight-loss surgery to see if the surgery can help prevent a specific type of heart problem (HFpEF) that sometimes develops in people carrying excess weight. Researchers will track your heart health and metabolism before and after surgery.
Heerlen, LimburgAges 35 years+ - NCT06463964Enrolling by invitation
Predicting kidney injury in emergency heart failure patients
This study looks at what factors might predict acute kidney injury (sudden kidney damage) in people who come to the emergency room with acute decompensated heart failure (a sudden worsening of heart failure). The goal is to help doctors identify who is at highest risk so they can take steps to protect the kidneys.
SohagAges 18 years+ - NCT07753681Recruiting
Chronic disease care in Zambia
This study helps improve care for people with long-term illnesses like diabetes or high blood pressure in Zambia. It aims to make sure you get regular check-ups and support.
Lusaka, Lusaka ProvinceAges Any age - NCT06428097RecruitingPhase 1
Thyroid hormone before heart transplant
This study tests whether giving a thyroid hormone supplement called levothyroxine before a heart transplant can help with recovery. It is for people already listed for a heart transplant who do not have thyroid problems.
San Francisco, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 981 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.