Clinical trials
Heart Valve Diseases clinical trials
Below are recruiting heart valve diseases clinical trials, each written for real people, not researchers. We’re tracking 227 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07516444Recruiting
Tricuspid valve replacement using a new catheter device
This trial tests a new device that replaces a leaky tricuspid valve (a heart valve) without open-heart surgery. If your tricuspid valve isn't working well and medicines haven't helped enough, this procedure might improve your heart function and symptoms.
Minneapolis, MinnesotaAges 18 years+ - NCT07511673Recruiting
Dental screening before heart valve surgery
This trial tests whether a dental checkup before heart valve surgery can improve recovery and prevent complications. If you are scheduled for a heart valve procedure, you may be able to join.
GothenburgAges 18 years+ - NCT07516145Recruiting
Robotic catheter repair for leaky tricuspid heart valve
This trial tests a new robotic catheter procedure to repair a leaky tricuspid valve (the valve on the right side of your heart). Instead of open-heart surgery, doctors thread a tiny device through a vein in your neck to fix the valve. It may be an option if you have severe leaking and your heart team thinks surgery is too risky for you.
ShatinAges 18–90 - NCT07483203Recruiting
Lung blood vessel health in people getting heart valve procedures
This study looks at how lung blood vessels work in people who are getting their heart valve fixed or replaced. It may help doctors understand and manage related lung issues.
Rochester, MinnesotaAges 18 years+ - NCT07476703Recruiting
Extended study on the SCAPIS Stockholm reexamined group
This trial studies data and samples from people already taking part in the main SCAPIS reexamination study in Stockholm. It looks for new findings to help understand heart and lung health.
StockholmAges 56–74 - NCT07456085Enrolling by invitationPhase 3
Rivaroxaban vs warfarin for mechanical heart valves
This trial compares a newer blood thinner (rivaroxaban) to the standard one (warfarin) for people with mechanical heart valves who have had clots or bleeding while on warfarin, or who cannot easily monitor their INR levels. It aims to see if rivaroxaban is safer and more effective.
Rawalpindi, Punjab ProvinceAges 18 years+ - NCT07462624Recruiting
Comparing treatments for a failing surgical aortic valve
This trial compares two ways to treat a failing aortic valve that was replaced with a tissue valve during surgery: another surgical replacement or a less invasive catheter-based valve-in-valve procedure. It is for people with low to intermediate surgical risk who are between 18 and 75 years old.
Leipzig, SaxonyAges 18–75 - NCT06838611Recruiting
Study of patients with severe tricuspid regurgitation
This study is collecting information about people with severe tricuspid regurgitation (a leaky heart valve) who are having a catheter-based repair. The goal is to better understand these patients and how well the procedure works for them.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT07296016Recruiting
Asia-Pacific mitral and tricuspid valve replacement registry
This study collects information from patients in the Asia-Pacific region who have had or plan to have a procedure to replace a failing mitral or tricuspid valve with a new valve placed inside the old one (called valve-in-valve) or inside a ring that was used in a previous repair (valve-in-ring). The goal is to learn more about how well these procedures work and how they can be improved.
Hong Kong, ShatinAges 21 years+ - NCT07267117Recruiting
Heart valve disease progression and outcomes study
This study is following people with heart valve disease (leaky or narrowed valves) to understand how the disease changes over time and what problems it may cause. It does not test a new treatment, but helps doctors learn more about valve disease progression.
Fuzhou, FujianAges 18 years+ - NCT07243184Recruiting
Polymer heart valve study for mitral valve disease
This trial is testing a new polymer artificial heart valve for people with severe mitral valve problems. It aims to see if this valve is safe and works well during surgical replacement.
BeijingAges 60 years+ - NCT05996120Recruiting
Finding the best temperature during heart-lung machine surgery
This study looks at the best body temperature to use during heart surgery when a heart-lung machine is needed. You may be able to join if you are having bypass surgery or valve repair, your risk score is moderate or higher, and your surgery is not an emergency.
Leicester, LeicestershireAges 18 years+ - NCT07224906Recruiting
Observing patients having a right heart catheterization
This study observes people who are already scheduled for a right heart catheterization, a procedure that checks the pressure in your heart. It helps doctors learn more about heart conditions without adding any extra treatments or procedures.
Boulder, ColoradoAges 18 years+ - NCT07214376Recruiting
Nerve ablation for pulmonary hypertension from left heart disease
This trial tests a device that uses a catheter to deliver energy to nerves around the pulmonary arteries, aiming to reduce high blood pressure in the lungs caused by left heart failure. It is for people with ongoing heart failure symptoms despite optimal medications.
Tucson, ArizonaAges 18–85 - NCT07196930Recruiting
Valvular heart disease in women registry
This study is a registry that collects data on women with valvular heart disease (heart valve problems). It aims to better understand how these conditions affect women and improve their care. You may join if you have a heart valve condition and are treated at a participating center.
AswānAges 18 years+ - NCT07112391Recruiting
Pressure volume loop study for valve disease
This trial uses a special heart test called pressure volume loop assessment to better understand how well your heart pumps when you have severe valve disease. It aims to find patterns that may help doctors treat you more effectively. You may join if you have certain types of severe heart valve problems.
Nantes, Loire AtlantiqueAges 18 years+ - NCT07099859RecruitingPhase 4
Losartan after aortic valve surgery for severe leakage
This trial tests if the drug losartan can help the heart recover better after surgery to replace a leaky aortic valve. It may reduce strain on the heart and improve long-term outcomes.
São Paulo, São PauloAges 18–85 - NCT07099417Recruiting
Screening for heart valve disease with a single-lead ECG
This study tests whether a simple single-lead heart monitor (ECG) can spot problems with your heart valves. It may be a quick, easy way to screen for valve disease.
MoscowAges 18 years+ - NCT07097740Recruiting
Study of a new polymer heart valve for mitral or aortic replacement
This study tests a new type of prosthetic heart valve made from a special polymer material. It is for adults who need surgical replacement of either the mitral or aortic valve.
Shanghai, Shanghai MunicipalityAges 50 years+ - NCT07069673Recruiting
Abbott Cephea mitral valve disease registry
This study tracks people with mitral valve disease who receive the Cephea valve through a tube in an artery rather than open-heart surgery. It looks at how well the valve works over time.
Birmingham, AlabamaAges 18 years+ - NCT07058935Recruiting
Heart valve re-replacement study for Asia-Pacific patients
This study looks at how well a new valve works when placed inside a previous mitral or tricuspid valve repair or replacement. It may help people who need another procedure on these heart valves.
New Lambton HeightsAges 21 years+ - NCT07001007Recruiting
Heart vibration test for cardiovascular risk
This trial uses a special device that measures vibrations from your heart to see if it can better predict your risk for heart disease. It's for people already in the larger SCAPIS 2 study who had an echocardiography exam.
StockholmAges 58–72 - NCT06917586Recruiting
Mosaic mitral valve study for patients under 65
This study looks at long-term results in people under 65 who received a specific type of replacement heart valve (the Mosaic mitral valve) during surgery at ProMedica Toledo Hospital. It aims to understand how well the valve works over time.
Toledo, OhioAges 18–65 - NCT05972070Recruiting
Telemedicine home cardiac rehab after heart procedure
This trial studies whether cardiac rehabilitation done at home, with help from telemedicine, is safe and helps you stick with the program after a recent heart procedure. It may help you recover with more convenience while still improving heart-related fitness and adherence.
Brookfield, ConnecticutAges 18 years+
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Common questions
- Are there clinical trials for heart valve diseases?
- Yes. Clin2 currently lists 227 recruiting heart valve diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart valve diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart valve diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.