Clinical trials
Hip Arthroplasty clinical trials
Below are recruiting hip arthroplasty clinical trials, each written for real people, not researchers. We’re tracking 154 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07227064RecruitingPhase 3
Methadone for pain relief after hip replacement surgery
This study tests whether a single dose of methadone given during hip replacement surgery can better control pain and reduce the need for other opioid painkillers afterward. It may help you recover with less pain and fewer side effects.
Charleston, South CarolinaAges 18–75 - NCT07153003Enrolling by invitationPhase 4
Tramadol and oxycodone vs oxycodone alone for joint pain
This trial tests if taking two pain relievers (tramadol and oxycodone) together works better than oxycodone alone to control pain after knee or hip replacement surgery. It aims to find a more effective way to manage pain with fewer side effects.
Rochester, MinnesotaAges 18 years+ - NCT06956950RecruitingPhase 2/Phase 3
Magnesium Added to Numbing Medicine for Hip Replacement Pain
This study tests whether adding magnesium sulfate to a numbing medicine (bupivacaine) can provide better pain relief after hip replacement surgery. The medicine is given as a shot in the back near the hip muscles.
Tanta, El-GharbiaAges 18 years+ - NCT06917365Recruiting
Testing a new liner for SERF hip replacements
This trial is testing a new liner (the inner part) for a specific brand of hip replacement called SERF. It's looking at how well it works in people who need a total hip replacement.
DijonAges 18 years+ - NCT06903767Enrolling by invitation
Automated vs manual tool study for hip replacement
This trial tests whether an automated surgical tool is better than a manual one for putting in hip replacement parts. If you are having a planned first-time hip replacement and are over 18, you might be able to join.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06831045Recruiting
Bikini vs Straight Incision for Hip Replacement
This study compares two types of skin cuts (a bikini-line incision vs a straight side incision) for total hip replacement through the front of the hip. It is designed for people with a BMI of 30 or higher to see which incision heals better and leads to fewer wound problems.
Miami, FloridaAges 18 years+ - NCT06807866RecruitingPhase 4
Duloxetine for pain after hip replacement surgery
This trial tests if duloxetine, a medication that helps with nerve pain, can reduce pain after hip replacement surgery. It may help patients who are having a first-time total hip replacement.
Miami, FloridaAges 18 years+ - NCT06748885Recruiting
Mpact 3D metal hip replacement study
This trial tests a new 3D-printed metal hip implant for people who need a first-time hip replacement. It aims to see how well the implant works and helps you recover.
NantesAges 18–75 - NCT05898581Recruiting
Compare two pain block methods for hip replacement surgery
This trial studies whether one type of numbing injection (a PENG block) works better than another method (local anesthetic injected into the surgical area) to control pain during and after total hip replacement. It may help choose the best pain plan for people having a specific surgical approach.
London, OntarioAges 19 years+ - NCT05818891Recruiting
Study of a hip implant for people needing first hip replacement
This trial studies a specific hip implant (from Medacta) for people who need their first total hip replacement. It aims to see how well the implant works and whether patients recover mobility safely.
Dracy-le-FortAges 18–80 - NCT05653687Recruiting
Hip replacement surgery: X-ray guidance versus usual hand placement
This trial compares two ways of guiding hip replacement surgery during the operation. It may help improve how accurately the surgeon places the hip components and how well patients do afterward.
Lugano, Canton TicinoAges 18–90 - NCT05658796Recruiting
Program to reduce opioid use after hip or knee replacement
This trial tests a support program called RXWell to help people use less opioid pain medicine after elective hip or knee replacement surgery. It may help by addressing anxiety and depression symptoms that can affect pain and recovery.
Monroeville, PennsylvaniaAges 18–100 - NCT05547984Recruiting
Ceramic hip implant study for first-time hip replacement
This trial tests a specific type of ceramic “dual mobility” hip implant for people getting their first total hip replacement (cementless). It may help reduce certain hip problems by using a designed implant that’s meant to move more safely.
Ústí nad LabemAges 18 years+ - NCT05221554Recruiting
Pre-surgery hip replacement modeling study
This trial tests a new way to plan hip replacement surgery using a CT scan. It may help doctors place the new hip more accurately, which could lead to better outcomes.
London, OntarioAges 40 years+ - NCT05247255Enrolling by invitationEarly Phase 1
Nerve block during hip replacement surgery
This early-stage study tests whether a specific nerve block to numb the lower back area can make total hip replacement surgery more comfortable. It looks at patients who are having planned (elective) hip replacement and whether the nerve block is safe and works well.
Santa Monica, CaliforniaAges 18 years+ - NCT04147559Enrolling by invitation
Long-term follow-up for a specific hip replacement stem
This study checks how well a particular hip replacement stem (the PROFEMUR Preserve Classic Femoral Stem) and matching parts keep working over many years. You may be invited if you had that exact hip replacement combination and can return for long-term checkups.
Scottsdale, ArizonaAges 21 years+ - NCT02301182Enrolling by invitation
Compare two hip implant types for younger hip arthritis
This trial compares two different hip implant designs in people ages 40–65 with primary hip osteoarthritis. It looks at how well the hip works afterward—especially function and everyday results.
AarhusAges 40–65 - NCT07598552Recruiting
Brain Function Changes After Same-Day Hip or Knee Surgery
This study checks whether patients who have hip or knee replacement surgery and go home the same day experience any temporary changes in thinking or memory. Researchers want to understand how anesthesia and surgery affect the brain in the short term.
SvendborgAges 70 years+ - NCT07845695Recruiting
Music before joint replacement surgery to ease anxiety
This study tests whether listening to music just before hip or knee replacement surgery can help reduce anxiety. If you are having surgery for arthritis and are comfortable listening to music, you may be able to join.
New York, New YorkAges 18 years+ - NCT06527664Recruiting
Custom hip implant for failed arthritis treatments
This trial tests a custom-made hip socket implant for people who have had a failed hip replacement or arthritis treatment. It aims to see if a personalized implant can provide a better solution.
BolognaAges 18 years+ - NCT06747494Recruiting
Comparing general vs spinal anesthesia for hip or knee replacement
This study compares two types of anesthesia (general and spinal) for people having a total hip or knee replacement. The goal is to see which approach is better for recovery and overall outcomes.
Miami, FloridaAges 18 years+ - NCT06208267Recruiting
Tranexamic acid for pain and bleeding after hip or knee replacement
This study tests whether a medicine called tranexamic acid (TXA) can reduce pain, improve movement, and lessen bleeding after hip or knee replacement surgery. It is for adults having their first joint replacement at St. Mary's Hospital.
Montreal, QuebecAges 18 years+ - NCT06145516Recruiting
Sleep program to ease pain after joint replacement
This study tests whether a sleep program can help with pain after knee or hip replacement. If you have insomnia and arthritis pain, you may be able to join before your surgery.
Uppsala, UpplandAges 18–100 - NCT05788016Recruiting
Help planning an opioid taper before knee or hip surgery
This study looks at a plan to safely reduce (taper) opioid pain medicines before total knee or hip replacement surgery. It may help people who are already taking opioids and are preparing for surgery in the next 1 to 2 months.
Birmingham, AlabamaAges 18 years+
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Common questions
- Are there clinical trials for hip arthroplasty?
- Yes. Clin2 currently lists 154 recruiting hip arthroplasty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hip arthroplasty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hip arthroplasty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.