Clinical trials
Humans clinical trials
Below are recruiting humans clinical trials, each written for real people, not researchers. We’re tracking 1,228 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05361733RecruitingPhase 1
Safety and blood-drug study of XFB19 in healthy adults
This Phase 1 study tests whether XFB19 is safe and tolerable in healthy adults and how the drug moves through the body (what the blood levels look like). You would be in the study to help researchers understand early safety and dosing information.
Knoxville, TennesseeAges 18–55 - NCT05357170Recruiting
Testing gut bacteria changes after severe ICU illnesses
This study looks at changes in the microbiome (gut bacteria) in adults after serious ICU illnesses like sepsis, major trauma, or open heart/abdominal surgery. It may help researchers understand why recovery can be harder in some people and guide future treatments.
Gainesville, FloridaAges 18–110 - NCT05335811RecruitingPhase 1
PET scan test of a new radioactive drug for tumors and inflammation
This Phase 1 study tests whether a new PET imaging tracer (a small amount of radioactive medicine) is safe and how it moves through the body. It’s mainly for adults with cancer who have signs of inflammation or possible immune side effects, so doctors can see what’s happening in the body.
Houston, TexasAges 18 years+ - NCT05332899RecruitingPhase 1
Flu challenge study in healthy adults to test an investigational approach
This Phase 1 study tests an investigational influenza (flu) approach in a carefully selected group of healthy adults. It may help researchers understand how the flu challenge works and how well the treatment performs and is tolerated.
Atlanta, GeorgiaAges 18–49 - NCT05355272RecruitingPhase 2
Growth hormone treatment for Gulf War illness with low growth hormone
This Phase 2 study tests whether replacing growth hormone can improve symptoms in veterans with Gulf War Illness and adult growth hormone deficiency. It also checks that the treatment is safe for people with stable medications and hormone regimens.
Houston, TexasAges 18–64 - NCT05307939RecruitingPhase 2
Using tumor DNA tests to time treatment for HPV throat cancer
This study checks a blood test that looks for HPV tumor DNA to help doctors decide when to start routine treatment after surgery. It may help some people avoid starting treatment too early or too late based on how the test changes after the operation.
Miami, FloridaAges 18 years+ - NCT05299736Enrolling by invitation
Study of the effects of boat rides on onboard crew
This study looks at how being on high-speed boats affects people who serve as crew or passengers for work. It’s for volunteers who are onboard in a professional role.
GothenburgAges 17–70 - NCT05302271RecruitingPhase 1
Gene therapy for the heart problems in Friedreich's ataxia
This trial tests a one-time gene therapy that delivers a corrected copy of the frataxin gene directly to the heart. It aims to improve or stabilize heart function in people with Friedreich's ataxia who have early or advanced heart involvement.
New York, New YorkAges 12–50 - NCT05305287RecruitingPhase 4
Measuring liver energy use in people with diabetes and fatty liver disease
This study looks at how the liver uses energy (mitochondria) in people with type 2 diabetes and fatty liver disease. By understanding this, researchers may find better ways to treat liver problems.
San Antonio, TexasAges 18–80 - NCT05238740Recruiting
Compare fusion results after two spine surgeries with added biologics
This study compares two types of spine surgery (ALIF or XLIF) for one spinal level, and tests how well the bones fuse when a specific bone-forming product is used. It also looks at how patients feel and function after surgery.
BernAges 18–70 - NCT05222594Recruiting
Brain language study using electrodes during epilepsy care
This study looks at how the brain processes language using recordings from electrodes placed during epilepsy treatment. If you’re already being considered for this type of brain monitoring, the study’s tasks may help researchers better understand language function in the brain.
Boston, MassachusettsAges 18–85 - NCT05157282Recruiting
Spinal cord stimulation to improve hand function after tetraplegia
This trial tests whether a special device that stimulates the spinal cord can help people with long-lasting neck spinal cord injuries recover useful hand movement and grip strength. It may help your nervous system communicate better so daily hand tasks become easier.
Chicago, IllinoisAges 18–70 - NCT05196061Recruiting
Skin and gut sample study for healthy people
This study builds a detailed library of the microbes living on your skin and in your gut. It may help researchers better understand how these microbes relate to health and future diseases.
Cleveland, OhioAges 18 years+ - NCT04954664Recruiting
Bone graft particles to help dental implants fit in missing teeth areas
This study tests a bone-grafting approach (using processed donor bone particles, with or without a growth factor) to help dental implants work when the jaw bone is too narrow. It may help people get implants placed more safely and effectively in areas with missing teeth.
Birmingham, AlabamaAges 18–99 - NCT05075967Enrolling by invitation
Study attitudes and services among southern gay and bisexual men
This study gathers opinions and experiences from gay and bisexual men and from clinic staff in the American South. It helps researchers understand what affects HIV prevention and care, and how programs can better support people at higher risk.
Durham, North CarolinaAges 15 years+ - NCT05103683RecruitingPhase 1
First-time test of TORL-1-23 for advanced solid tumors
This early study tests a new drug (TORL-1-23) in people with advanced solid cancers. It aims to find the safest dose and see how the tumor responds.
Fullerton, CaliforniaAges 18 years+ - NCT05120596RecruitingPhase 1/Phase 2
Testing an immune-targeting drug by direct injection into tumors
This Phase 1/2 trial tests T3P, a new treatment given directly into reachable solid tumors, to see if it is safe and can help shrink tumors. It is for adults with advanced cancers when no curative treatment is available.
Pamplona, NavarreAges 18–74 - NCT05067179Recruiting
ALS patient data and tissue study
This study collects information from people diagnosed with ALS and, if applicable, studies ALS tissue samples. It aims to improve understanding of ALS using patient records and donated materials, which may help future treatments.
Chicago, IllinoisAges 18–90 - NCT05107947Recruiting
Dynamic room lighting to improve sleep and daily body rhythm
This study tests whether changing the light in a hospital room can improve sleep and help your body clock work better in older adults. It may be most helpful if sleep problems or irregular daily rhythms are affecting you in the hospital.
MalmöAges 65 years+ - NCT05120635Recruiting
Study brain signals tied to fear and anxiety in RNS patients
This study records electrical brain activity to understand how fear and anxiety work in people who already have an RNS (responsive neurostimulation) device placed. It may help researchers develop better ways to monitor and treat anxiety-related symptoms in the future.
Los Angeles, CaliforniaAges 18–70 - NCT05071079Recruiting
Study infects volunteers with a malaria germ to test treatment
This study gives healthy volunteers a controlled infection with a type of malaria (vivax) to see how the infection behaves and how well curative anti-malaria medicine works. It may help researchers better design and test future malaria vaccines and treatments.
BangkokAges 20–55 - NCT05093335RecruitingEarly Phase 1
PET scan test for CXCR4 in many relapsed cancers
This early study tests a new PET scan tracer (a radioactive imaging agent) that may light up a cell marker called CXCR4 in certain blood and solid tumor cancers. It may help doctors see where cancers are and how much CXCR4 they have, which could guide future treatments.
New York, New YorkAges 18 years+ - NCT05108818RecruitingPhase 4
Study immune responses after an flu shot in healthy adults
This study gives you a flu vaccine and measures how your immune system reacts, including both “blood immunity” and “cell immunity.” It’s for healthy adults and mainly aims to better understand how well flu vaccines work in people without major health issues.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05065216RecruitingPhase 2/Phase 3
Study drug for acute ischemic stroke started within 24 hours
This trial tests whether an investigational study drug can improve outcomes after an acute ischemic stroke (a stroke caused by blocked blood flow). You may be eligible if you are able to start treatment quickly after symptom onset and have a moderate stroke severity on a standard stroke exam.
Fairhope, AlabamaAges 18–90
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Common questions
- Are there clinical trials for humans?
- Yes. Clin2 currently lists 1,228 recruiting humans studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a humans trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a humans trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.