Clinical trials · Charlotte, NC
High blood pressure clinical trials in Charlotte
We’re tracking 11 recruiting high blood pressure studies with a site in or near Charlotte — including Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Charlotte
- NCT05129345Recruiting
HIV care program for heart health goals in the Southeast US
This trial tests an approach to help people living with HIV reach heart- and metabolism-related health goals, such as blood pressure, cholesterol, and blood sugar. It involves clinics and community partners and may offer education, support, and care coordination to remove barriers to treatment.
Charlotte, North CarolinaAges 18 years+ - NCT06059638Recruiting
Pacemaker pacing for blood pressure control
This study tests whether adjusting the timing of a pacemaker can help lower blood pressure in people who already have or need a pacemaker. It could be an option for those whose blood pressure is not well controlled with medication.
Charlotte, North CarolinaAges 18 years+ - NCT06526195Recruiting
A study of CardioMEMS and HeartMate 3 for advanced heart failure
This trial tests if a combination of a tiny lung-artery pressure sensor (CardioMEMS) and a mechanical heart pump (HeartMate 3) is safe and effective for people with advanced heart failure. If you qualify, you'll either get the heart pump plus standard medical therapy, or continue with standard therapy alone and have your pressure monitored remotely.
Charlotte, North CarolinaAges 18 years+ - NCT07142356RecruitingPhase 2
New oral medication for high blood pressure not controlled by current pills
This study tests a new medication, RTN-001, for people whose blood pressure remains high even when taking multiple blood pressure medications. The goal is to see if this drug can lower blood pressure more effectively.
Charlotte, North CarolinaAges 18–75 - NCT07064473RecruitingPhase 3
Testing vicadrostat plus empagliflozin for diabetes, high blood pressure, and heart disease
This study tests a new pill called vicadrostat taken with another medicine (empagliflozin) to see if it helps people with type 2 diabetes, high blood pressure, and heart disease. It may reduce the risk of heart problems, but you must not have had heart failure or use certain other heart medications.
Fort Mill, South CarolinaAges 18 years+ - NCT07511361RecruitingPhase 2
Tonlamarsen for high blood pressure after hospitalization
This study tests an investigational medication (Tonlamarsen) for people who were recently hospitalized for a very severe high blood pressure episode and also have heart or kidney disease. It aims to see if the drug can help control blood pressure after discharge.
Fort Mill, South CarolinaAges 18 years+ - NCT07543120RecruitingPhase 2
Extended Safety Study of QCZ484 Blood Pressure Medication
This is a continuation study for people who completed a previous QCZ484 trial and tolerated it well. Researchers will monitor how safe and effective the medication remains with longer-term use for managing high blood pressure.
Monroe, North CarolinaAges 18 years+ - NCT07181109RecruitingPhase 3
Study of zilebesiran for high-risk hypertension patients
This trial tests a new medicine called zilebesiran for people with high blood pressure that isn't well controlled. It may be an option if you have heart or blood vessel disease, or are at high risk for it.
Monroe, North CarolinaAges 18 years+ - NCT07610278RecruitingPhase 2
Blood Pressure and Cholesterol Treatment Study
This study tests a combination of two new medications (QCZ484 and inclisiran) designed to lower both blood pressure and cholesterol levels. You may be a good fit if you have high blood pressure and high cholesterol that isn't fully controlled by current treatments.
Monroe, North CarolinaAges 18–75 - NCT06343298RecruitingPhase 2
Study of manp for hard-to-control high blood pressure
This study tests a new investigational drug called MANP to see if it can lower blood pressure in people whose blood pressure stays high even when they are already taking several medications. If it works, this drug might offer a new option for people with difficult-to-control hypertension.
Monroe, North CarolinaAges 18–80 - NCT06742723RecruitingPhase 3
Study of baxdrostat and dapagliflozin for kidney disease and high blood pressure
This trial tests if combining baxdrostat with dapagliflozin helps protect kidney function and reduce heart risks in people with chronic kidney disease and high blood pressure. It's for adults who are already taking standard blood pressure medications.
Statesville, North CarolinaAges 18 years+
Hear when a new High blood pressure trial opens near Charlotte, NC
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High blood pressure trials in other cities
Where these studies are running near Charlotte
Institutions with a site for the recruiting high blood pressure studies listed above.
- Monroe Biomedical Research · 3 studies
- Accellacare of Piedmont, Piedmont Healthcare
- Atrium Health Carolinas Medical Center
- Atrium Health Sanger Heart
- Clinical Trial Site
- Duke University - Charlotte Study Sites
- OnSite Clinical Solutions, LLC
- Piedmont Research Partners, LLC
What taking part in a high blood pressure study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting high blood pressure studies in North Carolina.
Common questions
- Are there high blood pressure clinical trials near Charlotte?
- Yes. We're currently tracking 11 recruiting high blood pressure studies with a site near Charlotte, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a high blood pressure study near Charlotte?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Charlotte to take part?
- Not necessarily. These studies have a site near Charlotte, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New high blood pressure studies open near Charlotte regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.