Clinical trials
High blood pressure clinical trials
Persistently raised blood pressure, a major risk factor for heart disease and stroke. We’re tracking 988 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05156736Recruiting
Study of early heart artery disease in South Asians
This study looks at early buildup of plaque in heart arteries in young adults from Pakistan. It may help doctors understand why this happens earlier and guide better prevention and screening.
Karachi, SindhAges 35–65 - NCT05168605Recruiting
Targeted home visits for adults with diabetes and high blood pressure
This study tests whether tailored visits from a care team at your home can improve ongoing health problems from high blood pressure and poorly controlled blood sugar. It may help you by making care easier to follow and more personalized to your daily life.
Dallas, TexasAges 18–60 - NCT05183763Recruiting
Program to help improve blood pressure medication use
This trial tests a medication adherence program to help people with high blood pressure take their blood pressure medicines more reliably. It may help lower blood pressure by improving refill timing and daily medication use.
Baton Rouge, LouisianaAges 40 years+ - NCT05201144RecruitingPhase 2
Test of sildenafil after diaphragm hernia surgery in newborns
This trial studies whether sildenafil (a medicine that helps relax blood vessels) can improve outcomes in babies born with a congenital diaphragmatic hernia (CDH) after they’ve had surgery. Babies are selected based on an ultrasound/echo of heart function after repair.
Salt Lake City, UtahAges Any age - NCT05232240Recruiting
Study blood pressure swings after stroke or TIA
This trial studies changes (“swings”) in blood pressure in people who recently had an ischemic stroke or a TIA. It may help doctors understand how blood pressure fluctuations affect recovery, even when you do not have known hypertension.
Beijing, BJAges 18 years+ - NCT05236348Recruiting
Testing an optical blood pressure monitor against standard checks
This trial checks whether an optical device can measure your blood pressure as accurately as the usual method used by clinicians. You may be asked to come for 9 visits and do brief exercises while measurements are taken.
LausanneAges 21–85 - NCT05242055Recruiting
Tracking and treating chronic kidney disease risk
This trial looks at how well an integrated program for identifying and treating people at risk for chronic kidney disease (CKD) can improve outcomes. It may help by catching problems earlier and guiding treatment sooner.
Beijing, Beijing MunicipalityAges 18–100 - NCT05248412Recruiting
Study how COVID-19 long-term effects impact chronic diseases
This research looks at how the COVID-19 pandemic has affected the health and healthcare of adults with long-term conditions like diabetes, high blood pressure, heart disease, cancer, kidney disease, or chronic lung disease. It compares people who may have been affected by the pandemic and looks at their health and access to care over time.
Hong Kong, Hong KongAges 18 years+ - NCT05252208Recruiting
Stretching or walking to lower blood pressure
This study compares stretching versus walking to see which helps lower blood pressure. It may help you learn a safe, low-cost routine to improve blood pressure if you have mildly high readings.
Saskatoon, SaskatchewanAges 18 years+ - NCT05293756Recruiting
Helping African American adults take blood pressure medicines consistently
This study tests whether a technology-based program (like a smartphone app or videos) can help you take your blood pressure medicines more reliably and improve blood pressure control. It mainly targets adults who need help staying on a multi-drug treatment plan.
Cleveland, OhioAges 50 years+ - NCT05312892RecruitingPhase 1/Phase 2
Study for weight-related hormone signals in people with high blood pressure
This early-phase study looks at how the body’s “fight-or-flight” signals may be involved in weight gain (obesity) and high blood pressure. It may help researchers understand the biology and guide future treatments.
Nashville, TennesseeAges 18–65 - NCT05321368Recruiting
Program to help control blood pressure and support health equity
This study tests a program that combines clinic care, community support, and phone-based monitoring to help people better manage blood pressure and related health problems. It aims to reduce health differences between groups that have been affected more by preventable disease.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05325437Recruiting
Laparoscopic spleen surgery to protect liver function in cirrhosis
This trial looks at whether a minimally invasive spleen surgery (with a specific vein-disconnection procedure) can better protect liver function in people with cirrhosis who have had variceal bleeding. It may help reduce stress on the liver after treatment, but you must meet several safety criteria.
Yangzhou, JiangsuAges 18 years+ - NCT05340062Recruiting
Noninvasive brain-pressure check versus invasive test in children
This trial compares a noninvasive way to measure brain pressure to an invasive method in children. It may help reduce the need for painful or risky procedures while still getting useful measurements for care.
BolognaAges Up to 18 years - NCT05363761RecruitingPhase 1
Artery procedure to treat type 2 diabetes and related problems
This Phase 1 study tests a new artery “ablation” procedure for people with type 2 diabetes, aiming to improve diabetes and related conditions like high blood pressure. It will also check whether the procedure is safe and works well enough to study further.
Panama CityAges 21–65 - NCT05368467Recruiting
Registry study for pulmonary hypertension patients
This is a long-term study that enrolls people who have been diagnosed with pulmonary hypertension (high blood pressure in the lung arteries). It collects medical information over time to better understand the condition and what to expect.
Guangzhou, GuangdongAges Any age - NCT05369065RecruitingPhase 1
Artery ablation for type 2 diabetes with kidney and liver arteries
This Phase 1 study tests whether a minimally invasive artery procedure can improve type 2 diabetes and related health problems by targeting kidney and liver blood vessels. Because it’s early-stage, the main goal is safety and learning how the treatment works in people who meet specific diabetes, blood pressure, and blood test requirements.
TbilisiAges 21–65 - NCT05411029Recruiting
Study on sleep problems in Somali adults
This study looks at how disrupted sleep shows up in Somali adults without certain health conditions. It may help researchers understand sleep patterns in this community and improve future sleep support.
Rochester, MinnesotaAges 18–70 - NCT05413057Recruiting
Testing blood pressure pills with two or three medicines
This trial studies whether fixed-dose blood pressure medicines—either two drugs (fimasartan + amlodipine) or three drugs (fimasartan + amlodipine + hydrochlorothiazide)—work well and are safe. It may help your care team compare how these combinations control blood pressure and what side effects occur.
SeoulAges 19 years+ - NCT05452889RecruitingEarly Phase 1
PET scan study in pulmonary hypertension related to scleroderma
This early study uses a PET scan (a type of imaging test) to better understand lung blood-vessel disease in people who have pulmonary hypertension related to scleroderma. It may help researchers find how imaging signals relate to disease and risk.
Pittsburgh, PennsylvaniaAges 18–75 - NCT05453877Recruiting
Brain scan and health data study using a long-term cohort
This study uses existing health records and then collects or uses brain imaging (CT or MRI) along with basic health measurements. It may help researchers learn patterns in brain images that relate to health or disease risk in people from the Kailuan group.
Beijing, Beijing MunicipalityAges 18–90 - NCT05460416RecruitingPhase 3
Aspirin prevention in early pregnancy after frozen embryo transfer
This trial tests whether taking baby-dose aspirin after a frozen embryo transfer can lower the chance of developing pre-eclampsia, a blood-pressure problem that can happen during pregnancy. It targets women considered at higher risk based on specific health factors and pregnancy details.
LiègeAges 18–43 - NCT05473520RecruitingPhase 3
Doxycycline add-on therapy for lung improvement in tuberculosis
This Phase 3 trial tests whether adding doxycycline to standard TB medicine can improve lung function and reduce lung tissue damage. It aims to see if patients recover better by targeting the lung response to TB.
Kota Kinabalu, SabahAges 21 years+ - NCT05476627Recruiting
Study risk factors for kidney disease from metabolic conditions
This study looks at risk factors and body “omics” information (like blood/tissue patterns) to better understand chronic kidney disease caused by metabolic diseases. It may help researchers find better ways to predict or manage kidney problems in people with these conditions.
Beijing, Beijing MunicipalityAges 18–80
Hear when a new High blood pressure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for high blood pressure?
- Yes. Clin2 currently lists 988 recruiting high blood pressure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high blood pressure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.