Clinical trials
High blood pressure clinical trials
Persistently raised blood pressure, a major risk factor for heart disease and stroke. We’re tracking 982 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05644548Recruiting
Eye scan study for people with common health conditions
This study uses a special eye scan (OCTA) to look at how blood vessels in the retina change in people with conditions like high blood pressure, diabetes, or abnormal cholesterol. It may help doctors better understand how these common illnesses affect the eyes.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05651724Recruiting
MASH screening study for people with diabetes or obesity
This study screens participants for MASH (a type of liver fat inflammation) using information about your health and risk factors. It may help you and your care team learn whether you could have MASH and need follow-up.
Brussels, Vlaams-brabantAges 18–75 - NCT05679206Recruiting
Postpartum care study for pregnancy blood-pressure complications
This study looks at people with preeclampsia during pregnancy and how their lung blood pressure and related symptoms change after delivery. It may help doctors better monitor and manage postpartum risks, especially involving the heart and lungs.
BernAges 16 years+ - NCT05703386Recruiting
Study MRI changes in small-vessel stroke disease
This study looks at how “small-vessel” changes in the brain develop after an ischemic stroke, using repeated MRI scans. It may help researchers better understand what causes these changes and how to track them over time.
Baltimore, MarylandAges 18 years+ - NCT05707442RecruitingPhase 3
Stent or standard treatment for idiopathic intracranial hypertension
This Phase 3 trial compares putting in a venous sinus stent versus using medicine alone for idiopathic intracranial hypertension (IIH). It aims to see which approach better protects vision and lowers pressure in the brain.
Beijing, Beijing MunicipalityAges 18–60 - NCT05719415Recruiting
Testing balloon treatment effects on lung blood-vessel surface area
This study looks at how a procedure called balloon pulmonary angioplasty changes measurements in lung blood vessels in people with chronic thromboembolic pulmonary hypertension. It may help doctors understand what changes the treatment makes and why.
Montreal, QuebecAges 18–75 - NCT05719454Recruiting
Pacemaker-based nerve therapy for high blood pressure
This study tests a new pacemaker programming method (nerve therapy) to help lower blood pressure. It may be an option if you need a dual-chamber pacemaker and your blood pressure stays high despite medicine.
PragueAges 18 years+ - NCT05746039RecruitingPhase 1/Phase 2
Testing semaglutide for advanced lung disease
This study checks whether semaglutide is safe and feasible for people with advanced lung diseases and higher body weight. It may help by testing a structured treatment approach, but it includes several health and safety limits.
Philadelphia, PennsylvaniaAges 18–80 - NCT05830305Recruiting
Phone app coaching after brain bleed to help blood pressure
This trial tests a mobile health app (WeRISE) to help people who survived an intracerebral hemorrhage (a type of brain bleed) monitor health and manage blood pressure after discharge. It may help you reduce the risk of problems related to high or unstable blood pressure.
Hong KongAges 18–85 - NCT05844384Recruiting
Testing a new eye drop bottle for glaucoma
This study checks whether a device called the Nanodropper helps deliver glaucoma medicine as well as standard use. It is for adults with stable primary open-angle glaucoma (or ocular hypertension) who are on a limited number of eye-pressure medicines.
Lackland Air Force Base, TexasAges 18 years+ - NCT05881447Recruiting
Study kidney disease patterns in people in Tanzania
This study looks at how common chronic kidney disease is, how it develops over time, and what risk factors are linked to it. It may help improve how kidney disease is recognized and managed in your community.
Bagamoyo, Coast RegionAges 18–99 - NCT05882370RecruitingPhase 2
Immunotherapy plus TIPS for liver cancer with blocked portal vein
This study tests whether adding the immunotherapy drug cadonilimab (and a related treatment plan) plus TIPS can help people with advanced liver cancer that has a tumor clot causing portal vein pressure problems. It aims to improve disease control while managing the circulation pressure in the liver.
Guangzhou, GuangdongAges 18–75 - NCT05888467Recruiting
Exercise study for women at risk of pregnancy heart problems
This study looks at how physical activity affects the heart and blood-vessel health “profile” in women who have risk factors for a pregnancy condition (called GHD, related to preeclampsia risk). It may help researchers find safer or more helpful activity guidance before pregnancy.
Diepenbeek, LimburgAges 18–50 - NCT05889650Recruiting
External drainage for severe TBI brain swelling
This study tests whether placing an external drainage tube in the lower back can reduce dangerous pressure in the brain after a severe traumatic brain injury. If you meet safety and brain-scan criteria, it may help the research team understand whether this approach is safe early after injury.
Gainesville, FloridaAges 18–65 - NCT05896579Recruiting
Study heart function during rest and exercise in COPD
This study measures how well the right side of your heart works when you are resting and when you exercise, in people with chronic obstructive pulmonary disease (COPD). It may help researchers better understand COPD-related heart strain and guide future care.
Aurora, ColoradoAges 40 years+ - NCT05903001Recruiting
Breathing muscle testing to help track lung disease
This study checks whether measurements of your breathing muscle (the diaphragm) can act as a useful “biomarker” to track lung disease. You might be asked to do breathing tests and follow study instructions, and your results may help researchers better monitor COPD, asthma, fibrosis, or pulmonary hypertension.
Aachen, North Rhine-WestphaliaAges 18 years+ - NCT05917275RecruitingPhase 4
Testing tests to predict how you’ll respond to blood pressure medicines
This study uses blood and other body measurements to predict how well certain blood pressure medicines will work for you. It may help doctors choose the best treatment sooner, based on your personal “multi-omics” (biomarker) results.
NijmegenAges 18–75 - NCT05937854RecruitingPhase 2
Tadalafil to help breathing in COPD with pulmonary hypertension
This Phase 2 study tests whether tadalafil can improve breathlessness in people with COPD and pulmonary hypertension (high blood pressure in the lungs). It may help you breathe more easily if your symptoms are driven by this specific lung circulation problem.
Aurora, ColoradoAges 35–89 - NCT05937685Recruiting
Lower blood pressure after a heart or stroke event
This trial tests ways to help lower blood pressure in people who have had a heart attack or stroke and are at higher risk for more problems. If your blood pressure is high, the program may help reduce risk by getting it under better control.
Downey, CaliforniaAges 35 years+ - NCT05942729Recruiting
Checking heart disease diagnosis using echo images and health data
This study looks at how well heart ultrasound (echocardiography) images and clinical information can be used to diagnose cardiac conditions. If you have a clear ultrasound study already or can get one with good image quality, your information may help improve diagnostic accuracy.
Pierre-BéniteAges 18 years+ - NCT05955339Recruiting
Using visit recordings and open notes to improve care experience
This study tests two ways of sharing what happened at clinic visits—recording visits and using an “open notes” patient portal—to help older adults manage long-term health conditions with a better experience. It’s likely to help if you have multiple chronic conditions and can use email or a patient portal.
Manchester, New HampshireAges 18 years+ - NCT05960604Recruiting
Monitoring blood pressure during surgery to predict low blood pressure
This study tests special ways of analyzing blood-pressure recordings during major surgery to better understand why some people develop low blood pressure (hypotension). If you have high blood pressure and need invasive blood-pressure monitoring, your surgery team will use readings to study patterns that may help predict or prevent low blood pressure.
AnkaraAges 18 years+ - NCT05962372Recruiting
Culturally tailored diet program for adults in Puerto Rico
This study tests a diet program designed to fit Puerto Rico culture and daily life. It may help adults with weight or blood sugar or blood fat concerns improve their health through regular check-ins.
San JuanAges 30–65 - NCT05963126Recruiting
Fetuin A test to predict kidney function decline
This study looks at a blood protein called fetuin A to see if it can forecast worsening kidney function over time in people with treated high blood pressure. It may help identify who is at higher risk for kidney decline so care can be adjusted earlier.
Ostrava, Czech RepublicAges 18–100
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Common questions
- Are there clinical trials for high blood pressure?
- Yes. Clin2 currently lists 982 recruiting high blood pressure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high blood pressure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.