Clinical trials
High blood pressure clinical trials
Persistently raised blood pressure, a major risk factor for heart disease and stroke. We’re tracking 980 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06302127Recruiting
Heart and diabetes care study for county residents
This trial tests a team-based care model for people with high blood pressure or diabetes living in county areas. It aims to improve long-term health by working with local family doctors.
Sanming, FujianAges 40–70 - NCT06814509Recruiting
HOPE program for pregnant women
This study tests a program called HOPE that helps pregnant women get the support they need for a healthy pregnancy. It is designed to make prenatal care more fair and accessible.
Corning, ArkansasAges 16–44 - NCT06801886Enrolling by invitationPhase 3
Silymarin for better kidney transplant success
This trial tests if adding silymarin (a milk thistle extract) to standard anti-rejection medicines helps protect the new kidney from damage. It may improve how well the transplanted kidney works over time.
MartinAges Any age - NCT05129345Recruiting
HIV care program for heart health goals in the Southeast US
This trial tests an approach to help people living with HIV reach heart- and metabolism-related health goals, such as blood pressure, cholesterol, and blood sugar. It involves clinics and community partners and may offer education, support, and care coordination to remove barriers to treatment.
Charlotte, North CarolinaAges 18 years+ - NCT06049420Recruiting
Lifestyle medicine for rural patients with chronic disease
This trial tests whether exercise therapy can help people with two or more chronic conditions like obesity, diabetes, or heart disease. It's designed for rural patients and requires a referral from your doctor.
Lewisburg, West VirginiaAges 18–64 - NCT06752772Recruiting
Wearable health coaching for blood pressure and weight
This study tests a digital health coaching program that uses a smartwatch and smartphone to help people manage conditions like high blood pressure, pre-diabetes, or weight. It aims to see if wearable technology can improve your health with personalized coaching.
SingaporeAges 21–75 - NCT06753786Recruiting
Blood thinner timing study for bleeding stroke patients
This study looks at when it is safest to start blood thinners to prevent blood clots (deep vein thrombosis) after a type of bleeding stroke called hypertensive intracerebral hemorrhage. Researchers want to find the best time to start this prevention treatment.
MoscowAges 18 years+ - NCT06742723RecruitingPhase 3
Study of baxdrostat and dapagliflozin for kidney disease and high blood pressure
This trial tests if combining baxdrostat with dapagliflozin helps protect kidney function and reduce heart risks in people with chronic kidney disease and high blood pressure. It's for adults who are already taking standard blood pressure medications.
Fairhope, AlabamaAges 18 years+ - NCT06741436Recruiting
Exercise testing after preeclampsia
This study looks at how the heart and blood vessels work after a pregnancy complicated by preeclampsia. It uses exercise testing to see if there are lasting effects, which may help improve long-term heart health monitoring and care.
Nashville, TennesseeAges 18 years+ - NCT06740838Recruiting
Overnight dexamethasone test for aldosterone screening
This trial is testing a new way to screen for a hormone problem called primary aldosteronism (which can cause high blood pressure) by giving a steroid pill (dexamethasone) overnight. You may be eligible if you have high blood pressure and an adrenal growth, and are already scheduled for a related hormone test.
Gdansk, Pomeranian VoivodeshipAges 40–75 - NCT06744231Enrolling by invitation
Thriving Hearts Postpartum Parent Survey
This study is for new parents in certain North Carolina counties who had a baby in the past 6 months. You will fill out a one-time survey to help improve maternity care and support for families.
Chapel Hill, North CarolinaAges 15 years+ - NCT06735599Recruiting
Wild blueberries for blood pressure health
This study tests whether eating wild blueberries can improve your gut, brain, and heart health if you have high blood pressure. You'll eat blueberries daily for several weeks and have checkups to see how your body responds.
Atlanta, GeorgiaAges 45–65 - NCT06115122Recruiting
PEPPI Study: Finding early signs of placental problems in pregnancy
This study looks at blood markers to find women at risk for placental problems during pregnancy. It involves blood tests in early and late pregnancy, and at birth, to see how iron levels and other factors affect the placenta and baby's health.
OuluAges Any age - NCT06710314Enrolling by invitation
Metabolic syndrome and recovery after colorectal cancer surgery
This trial studies how metabolic syndrome (a mix of high blood pressure, diabetes, and other factors) changes after colorectal cancer surgery. It aims to understand why some people's metabolic syndrome gets better after their tumor is removed, which could lead to better treatments.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT06687044Enrolling by invitation
Sleep therapy for better pregnancy outcomes
This study tests whether a sleep improvement therapy can help pregnant women (with one or two babies) by improving their sleep and pregnancy outcomes. It's for women who are early in their pregnancy and having sleep problems but are otherwise healthy.
Shenyang, LiaoningAges 18–45 - NCT06687863Enrolling by invitation
Exercise and genes in high blood pressure with sleep apnea
This study looks at how exercise and your genes affect blood pressure in people with both high blood pressure and obstructive sleep apnea (a condition where breathing stops briefly during sleep). It aims to see if a tailored exercise program can help you better control your blood pressure.
São Paulo, São PauloAges 45–70 - NCT06669715Recruiting
Physical fitness and heart health in adults
This study looks at physical fitness and blood flow in a wide range of adults. It aims to understand how fitness affects heart health across different people.
LjubljanaAges 18 years+ - NCT06280313Recruiting
Splenectomy with targeted therapy and immunotherapy for liver cancer
This trial tests whether removing the spleen (splenectomy) can improve the effectiveness of targeted therapy and immunotherapy for people with advanced liver cancer (HCC) who also have enlarged spleens due to portal hypertension. It aims to see if this combination can help control the cancer better.
Wuhan, HubeiAges 18–75 - NCT06649110RecruitingPhase 1/Phase 2
A study of LTP001 for healthy people and those with PAH
This study tests an investigational medicine called LTP001 for pulmonary arterial hypertension (PAH). Part A checks safety in healthy volunteers, and Part B tests if it helps people with PAH by improving blood flow in the lungs.
Scottsdale, ArizonaAges 18–100 - NCT06646250Recruiting
New ultrasound for steady brain monitoring in newborns
This trial uses a new ultrasound device (NeoDoppler) to watch blood flow in a baby's brain continuously. It aims to see if this gentle, bedside tool can help doctors monitor babies—especially those born early or with certain health concerns—without moving them.
TrondheimAges birth–1 year - NCT06647511Recruiting
Digital health study for pregnant refugees in NYC
This study tests a smartphone-based tool to help pregnant refugees and asylum seekers stay healthy during pregnancy. It aims to reduce complications and improve care for mothers and babies.
New York, New YorkAges 18 years+ - NCT06656130Enrolling by invitation
Breathing and relaxation for pre-hypertension
This trial tests two gentle techniques—deep breathing (Pranayama) and progressive muscle relaxation—to see if they can help lower blood pressure in people with pre-hypertension. You would attend practice sessions and follow-up visits.
Sialkot, Punjab ProvinceAges 30–60 - NCT06643819RecruitingPhase 3
Testing a new blood pressure drug
This trial tests a new combination blood pressure medicine called CKD-202A. It is for adults with high blood pressure who have not had other treatments or conditions that could affect the results.
WŏnjuAges 19 years+ - NCT06634069RecruitingPhase 2
Testing a new approach for septic shock patients
This trial tests a special fluid management strategy for people in septic shock—a serious infection that causes very low blood pressure. It aims to improve blood flow to organs and help you recover.
Pilsen, Czech RepublicAges 18–90
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Common questions
- Are there clinical trials for high blood pressure?
- Yes. Clin2 currently lists 980 recruiting high blood pressure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high blood pressure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.