Clinical trials
High blood pressure clinical trials
Persistently raised blood pressure, a major risk factor for heart disease and stroke. We’re tracking 980 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05309460RecruitingPhase 4
Labetalol or nifedipine to treat postpartum high blood pressure
This study compares two common blood pressure medicines—labetalol and nifedipine—to control high blood pressure after childbirth. It may help you and your care team find the safest way to bring your blood pressure back to normal after delivery.
Omaha, NebraskaAges 19 years+ - NCT06394934Recruiting
Home blood pressure changes and artery health in hypertension
This study looks at how changes in home blood pressure readings over time relate to hardening of the arteries and metabolic problems in people with high blood pressure. If you take medication for high blood pressure and monitor your pressure at home, you may help researchers understand these connections better.
SeoulAges 19 years+ - NCT07850934Recruiting
Melatonin for high blood pressure in the lungs of newborns
This trial tests whether giving melatonin to full-term newborns with high blood pressure in their lungs (pulmonary hypertension) can help improve their breathing and oxygen levels. It may offer a new treatment option for babies with this condition.
Cairo, AbbassiaAges Any age - NCT07852403Recruiting
Sleep problems and outcomes in pulmonary arterial hypertension
This study looks at how sleep-disordered breathing (abnormal breathing during sleep) affects the long-term health of people with pulmonary arterial hypertension (PAH), a type of high blood pressure in the lungs. By participating, you will have a sleep study and be followed over time to see how your breathing during sleep relates to your PAH outcomes.
BeijingAges 18 years+ - NCT07850908Enrolling by invitation
Ventilation method for newborns with persistent pulmonary hypertension
This study tests a specific type of breathing machine (ventilator) that adjusts air pressure to help newborns with persistent pulmonary hypertension breathe better. It aims to see if this method improves oxygen levels and outcomes for babies needing mechanical ventilation in their first week of life.
Tanta, Gharbia GovernorateAges 1 day–2 months - NCT06429579Recruiting
Potts shunt for severe pulmonary hypertension in children
This trial tests a surgery called a Potts shunt for children with severe pulmonary hypertension (high blood pressure in the lungs). It may help children who are still very sick despite standard medications.
Beijing, Beijing MunicipalityAges 6 months–18 years - NCT07848828RecruitingPhase 4
Blood pressure and kidney study for prostate cancer treatment
This study looks at how a common prostate cancer treatment called androgen deprivation therapy (ADT) affects blood pressure and kidney function. It may help doctors understand and manage these side effects better.
Richmond, VirginiaAges 40 years+ - NCT07837830RecruitingEarly Phase 1
Early treatment for exercise-related lung pressure
This trial tests an inhaled medicine that may help people with lung scarring or connective tissue disease who have high blood pressure in the lungs only during exercise. It aims to improve their ability to be active and reduce symptoms.
Paramus, New JerseyAges 18 years+ - NCT07827560Recruiting
Acupressure for better sleep in older adults with high blood pressure
This study tests whether acupressure (applying pressure to certain points on the body) can help improve sleep in older adults who have both high blood pressure and trouble sleeping. It aims to find a drug-free way to reduce insomnia and potentially improve overall well-being.
Hanoi, Son TayAges 60 years+ - NCT07822997Recruiting
Quality of Life Questionnaire for Pulmonary Hypertension in Brazil
This study is testing a questionnaire (EMPHASIS-10) to measure quality of life in people with pulmonary hypertension. The goal is to adapt it for Brazilian Portuguese speakers so doctors can better understand how the disease affects daily life.
Porto AlegreAges 18 years+ - NCT07824674RecruitingPhase 2/Phase 3
On-demand sildenafil for exercise capacity in pulmonary arterial hypertension
This trial tests whether taking sildenafil (a medicine that helps relax blood vessels) on demand, compared to a sugar candy placebo, can improve exercise capacity in people with pulmonary arterial hypertension (PAH). Participating may help you exercise more easily and contribute to better treatment options.
Zurich, Canton of ZurichAges 18–80 - NCT07814118Enrolling by invitation
Understanding how your body works during routine care
This study looks at how different body systems work together in people with various conditions and healthy volunteers. It uses routine medical tests and data to understand health better, which can help improve future care.
New York, New YorkAges 18 years+ - NCT07803835RecruitingPhase 1
Study of MWX401 for healthy adults and mild high blood pressure
This study tests a new medicine, MWX401, to see if it is safe and how it works in the body. It includes healthy adults and people with mild high blood pressure, with frequent check-ups to ensure safety.
Nanjing, JiangsuAges 18–60 - NCT07789535Recruiting
Sleep study for people with high blood pressure and poor sleep
This study looks at how improving sleep might affect blood vessel health in people with high blood pressure who don't sleep well. You might join if you have high blood pressure and poor sleep quality.
Guimarães, Braga DistrictAges 18–70 - NCT07784296Recruiting
Triple combination therapy for high blood pressure in Korean adults
This study tests a three-drug combination pill for high blood pressure in Korean adults. It aims to see if this treatment is safe and effective.
Gyeonggi-doAges Any age - NCT07777367Recruiting
Exercise with liquid oxygen in chronic lung disease
This study compares how well people with chronic lung diseases perform during exercise when breathing regular air versus when using low-flow liquid oxygen. It aims to see if using liquid oxygen during exercise can improve exercise ability and quality of life.
Zurich, Canton of ZurichAges 18 years+ - NCT07777445Recruiting
Oxygen treatment during exercise for lung and pulmonary vascular disease
This study compares breathing normal air versus low-flow liquid oxygen during exercise to see if oxygen helps improve performance in people with conditions affecting the lungs or the blood vessels in the lungs. You would exercise while using a portable oxygen device and then without it to compare the effects.
Zurich, Canton of ZurichAges 18 years+ - NCT07780500Recruiting
Using electronic health records to study people with high blood pressure
This study is not testing a new medicine. Instead, it is using electronic health records to better understand people with high blood pressure, with a focus on those recently diagnosed. If you join, you may help researchers learn more about how to improve care for others with high blood pressure.
Oakland, CaliforniaAges 18 years+ - NCT06093932RecruitingPhase 4
Songling Xuemaikang Capsules for mild high blood pressure
This study tests whether Songling Xuemaikang Capsules can help lower blood pressure in people with mild hypertension who are not currently on regular medication. It may offer a natural treatment option for managing early-stage high blood pressure.
Beijing, Beijing MunicipalityAges 35–65 - NCT07768865Recruiting
Artery stiffness in young people with kidney disease
This study looks at how stiff the arteries are in children and young adults with chronic kidney disease (CKD) compared to healthy controls. The results may help doctors better understand heart risks and improve care for young people with kidney problems.
London, Greater LondonAges 10–25 - NCT06568640Recruiting
Adrenal artery treatment for hard-to-control high blood pressure
This study tests a minimally invasive procedure called superselective adrenal arterial embolization for people whose high blood pressure is hard to control with medications. The goal is to see if this treatment can safely lower blood pressure.
NanchangAges 18 years+ - NCT07759804RecruitingPhase 4
Switching from selexipag to inhaled treprostinil for pulmonary arterial hypertension
This study tests whether switching from the oral medicine selexipag to an inhaled medicine called treprostinil can improve symptoms or side effects in people with pulmonary arterial hypertension (PAH). It may be an option if you are not getting enough benefit or are having trouble tolerating selexipag.
Columbus, GeorgiaAges 18–80 - NCT07758634RecruitingPhase 1/Phase 2
Study of an experimental treatment for high blood pressure
This trial tests a new treatment called CTX340 for high blood pressure that is hard to control even with multiple medications. The study aims to see if it is safe and effective.
Port Orange, FloridaAges 18–75 - NCT07751445Recruiting
Weight training for blood pressure control
This study tests whether exercising one arm or leg at a time versus both together can lower blood pressure better in people with hypertension. It may help you manage your blood pressure through a safe, supervised workout program.
TunceliAges 40–75
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Common questions
- Are there clinical trials for high blood pressure?
- Yes. Clin2 currently lists 980 recruiting high blood pressure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high blood pressure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.