Clinical trials
High blood pressure clinical trials
Persistently raised blood pressure, a major risk factor for heart disease and stroke. We’re tracking 982 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07318597RecruitingPhase 2
A study of an experimental drug for pulmonary arterial hypertension
This trial tests a new medication called REGN13335 for people with pulmonary arterial hypertension (PAH). It aims to see if the drug can improve symptoms and function compared to standard care alone.
Aurora, ColoradoAges 18 years+ - NCT07181109RecruitingPhase 3
Study of zilebesiran for high-risk hypertension patients
This trial tests a new medicine called zilebesiran for people with high blood pressure that isn't well controlled. It may be an option if you have heart or blood vessel disease, or are at high risk for it.
Birmingham, AlabamaAges 18 years+ - NCT07132788Recruiting
How PAH affects muscle mass
This study looks at how pulmonary arterial hypertension (PAH) impacts lean muscle mass. It may help researchers understand changes in your body and find new ways to support your health.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07322133RecruitingPhase 4
Comparing two blood pressure medicines for newborns with lung hypertension
This trial compares two medicines (dopamine and norepinephrine) to see which works better for raising blood pressure in newborns who have both low blood pressure and high blood pressure in the lungs. Both medicines are given through a vein to help stabilize your baby's blood pressure.
Sacramento, CaliforniaAges Up to 4 weeks - NCT07368608RecruitingPhase 1/Phase 2
Testing a new drug for high blood pressure and cholesterol
This study tests a new medicine called BEBT-701 for people with mild to moderate high blood pressure and high cholesterol. The goal is to see if it can lower both blood pressure and LDL ('bad') cholesterol safely.
Changsha, HunanAges 18–60 - NCT07768865Recruiting
Artery stiffness in young people with kidney disease
This study looks at how stiff the arteries are in children and young adults with chronic kidney disease (CKD) compared to healthy controls. The results may help doctors better understand heart risks and improve care for young people with kidney problems.
London, Greater LondonAges 10–25 - NCT07123779RecruitingPhase 1/Phase 2
Study of HS235 in obese patients with pulmonary hypertension and heart failure
This trial tests an investigational drug called HS235 in people who have both obesity (BMI 30-50) and a specific type of heart failure with preserved pumping function, along with high blood pressure in the lungs. The goal is to see if the drug can improve symptoms and quality of life.
Greenville, South CarolinaAges 18 years+ - NCT07143448RecruitingPhase 1/Phase 2
Study of HS235 for pulmonary arterial hypertension in adults
This trial tests an experimental drug called HS235 for people with pulmonary arterial hypertension (PAH), a condition of high blood pressure in the lungs. It aims to see if the drug can help improve symptoms and exercise ability.
Tampa, FloridaAges 18 years+ - NCT07179380RecruitingPhase 3
A study of an inhaled drug for lung disease with high blood pressure
This trial tests an inhaled medicine (TPIP) for people with both lung scarring (interstitial lung disease) and high blood pressure in the lungs (pulmonary hypertension). It aims to see if the drug helps improve exercise ability and symptoms.
Los Angeles, CaliforniaAges 18 years+ - NCT07234032RecruitingPhase 3
Long-term follow-up study of TPIP for PH-ILD
This trial is a long-term follow-up study for people who already completed a previous study of an inhaled treprostinil medication (TPIP) for pulmonary hypertension caused by interstitial lung disease (PH-ILD). It tests whether continued treatment with TPIP is safe and effective over a longer period.
Naples, FloridaAges 18 years+ - NCT07420907Recruiting
Tracking heart health over time
This study uses a wearable patch to monitor heart-related signs in people with heart conditions. It aims to learn more about how these conditions progress, which could help improve future care.
Chicago, IllinoisAges 18 years+ - NCT07747025Recruiting
Nurse-led talks to help control blood pressure
This study tests whether talking with a nurse can help you manage your blood pressure better. You'll have support from a family member and learn ways to keep your blood pressure in a healthy range.
SimavAges 18 years+ - NCT07758634RecruitingPhase 1/Phase 2
Study of an experimental treatment for high blood pressure
This trial tests a new treatment called CTX340 for high blood pressure that is hard to control even with multiple medications. The study aims to see if it is safe and effective.
Port Orange, FloridaAges 18–75 - NCT06992440RecruitingPhase 2
Empagliflozin for better right heart function in pulmonary hypertension
This trial tests if a diabetes drug can help people with pulmonary arterial hypertension whose right heart function is reduced. Participants take empagliflozin or a placebo for 24 weeks to see if heart function improves.
Baltimore, MarylandAges 18 years+ - NCT06526858Recruiting
Laparoscopic kidney nerve treatment for resistant hypertension
This study tests a new treatment called HyperQure RDN, a laparoscopic (keyhole) surgery that targets nerves near the kidneys to lower blood pressure in people with resistant hypertension. If you have tried multiple medications but your blood pressure is still high, this procedure might offer an alternative approach.
Orange, CaliforniaAges 22–80 - NCT07751445Recruiting
Weight training for blood pressure control
This study tests whether exercising one arm or leg at a time versus both together can lower blood pressure better in people with hypertension. It may help you manage your blood pressure through a safe, supervised workout program.
TunceliAges 40–75 - NCT07069491Recruiting
High blood pressure during dialysis: what causes it?
This study is looking at why some people develop high blood pressure during their dialysis sessions. Your participation could help doctors better manage this condition in the future.
SohagAges 18–70 - NCT06081881Recruiting
High blood pressure in lungs after a severe blood clot
This study monitors people who had a severe lung blood clot to see if they develop high blood pressure in the lungs over time. It aims to catch the condition early, so treatment can start sooner.
AsyutAges 18–80 - NCT05732077Recruiting
Stent decisions for kidney artery narrowing in hard-to-control blood pressure
This trial studies whether using a pressure-based test called fractional flow reserve (FFR) helps doctors choose the right kidney artery stent for people with narrowing of kidney arteries and high blood pressure. It may help improve blood pressure control while avoiding unnecessary procedures.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04484675RecruitingPhase 4
Milrinone during heart surgery for severe pulmonary hypertension
This trial tests whether giving milrinone through a vein and inhaled during mitral valve surgery helps people with severe pulmonary hypertension. The goal is to improve heart and lung blood-flow stability around the time of surgery.
Zagazig, Sharqia ProvinceAges 18 years+ - NCT04467333Recruiting
Registry for lung cancer patients at a pulmonary hypertension center
This is a hospital registry study that collects information from people with lung cancer. It looks at pulmonary hypertension (high blood pressure in the lungs) in relation to lung cancer, which may help doctors understand risk and care needs.
Giessen, HesseAges 18 years+ - NCT05884190Recruiting
Help for early high blood pressure after childbirth
This study tests a “trauma-informed” approach to detect and manage high blood pressure soon after delivery. It may help you get faster support and safer treatment during the early postpartum period.
New Haven, ConnecticutAges 18 years+ - NCT06500351Recruiting
Postpartum hypertension gene and aging study
This study looks at two things in women with postpartum hypertension (high blood pressure after giving birth). It tests a gene called Renalase and measures the length of telomeres (a marker of cell aging) to see if they are linked to this condition.
SohagAges 18–45 - NCT06343298RecruitingPhase 2
Testing MANP for hard-to-control high blood pressure
This trial tests a new drug called MANP for people whose blood pressure stays high despite taking three or more different types of blood pressure medications. The goal is to see if MANP is safe and effective in lowering blood pressure.
Little Rock, ArkansasAges 18–80
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Common questions
- Are there clinical trials for high blood pressure?
- Yes. Clin2 currently lists 982 recruiting high blood pressure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high blood pressure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.