Clinical trials
High blood pressure clinical trials
Persistently raised blood pressure, a major risk factor for heart disease and stroke. We’re tracking 980 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07005050Recruiting
Kidney nerve treatment for high blood pressure pilot study
This study tests a new treatment that uses a device to calm overactive nerves in the kidneys, which may help lower high blood pressure. It is for people who are already taking at least two blood pressure medications and still have high readings.
Birmingham, AlabamaAges 21–80 - NCT07132788Recruiting
Study of pulmonary arterial hypertension and lean muscle mass
This study looks at how pulmonary arterial hypertension (PAH) affects lean muscle mass. It aims to understand the relationship between PAH and muscle loss, which could help improve treatments and quality of life.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07181109RecruitingPhase 3
Study of zilebesiran for high-risk hypertension patients
This trial tests a new medicine called zilebesiran for people with high blood pressure that isn't well controlled. It may be an option if you have heart or blood vessel disease, or are at high risk for it.
Birmingham, AlabamaAges 18 years+ - NCT02608996RecruitingPhase 1/Phase 2
Nesiritide test for hard-to-control blood pressure
This Phase 1/2 study tests nesiritide, a medicine that affects blood vessels and heart strain, to see if it can improve blood pressure control in people with hypertension. It’s mainly for people whose blood pressure stays high even during the day despite medication.
OsloAges 18–79 - NCT03959748Recruiting
Pulmonary hypertension patients’ heart-lung pressure database study
This study builds a database of people with pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension. It may help doctors better understand these conditions in the Polish population and improve future care decisions.
KrakowAges 3 months+ - NCT04212455Recruiting
Study of blood tests linked to high blood pressure
This study looks at whether certain blood markers can help explain or predict high blood pressure in adults. It may help researchers understand hypertension better, which could support future prevention or treatment.
Guangzhou, GuangdongAges 18 years+ - NCT03269630Recruiting
Pulmonary hypertension biobank for heart-lung blood samples
This study collects and stores health information and possibly blood samples from people being evaluated for pulmonary hypertension or related autoimmune conditions. It helps researchers learn more about these illnesses and may support future studies.
New Orleans, LouisianaAges 18 years+ - NCT04578301Recruiting
Predicting who develops serious liver worsening after surgery
This study looks at your liver health before and after surgery to predict the risk of “acute-on-chronic liver failure,” which means a sudden worsening of liver function on top of an existing liver condition. If you qualify, your doctors may use study data to better identify who needs closer monitoring after surgery.
BonnAges 18 years+ - NCT05421767RecruitingPhase 4
Renal nerve stimulation for hard-to-control high blood pressure
This trial tests whether stimulating nerves around the kidney can lower blood pressure in people whose high blood pressure stays uncontrolled despite treatment. It may help by improving how the kidneys and blood vessels regulate blood pressure.
TaipeiAges 20 years+ - NCT05401357RecruitingPhase 3
Test eye drops for glaucoma or high eye pressure in both eyes
This Phase 3 study compares two versions of the same glaucoma eye-drop medicine (bimatoprost 0.01%) to see how similarly they work and their effect on eye pressure. It may help people with chronic open-angle glaucoma or ocular hypertension who need treatment in both eyes.
Newport Beach, CaliforniaAges 18 years+ - NCT05610631Recruiting
Switzerland heart-lung pressure registry for people with PH
This is a registry that collects information from people who have pulmonary hypertension (high blood pressure in the lungs). It helps researchers better understand the condition and may support future studies.
ZurichAges Any age - NCT05735444Recruiting
CPAP registry for sleep apnea in people with high blood pressure
This study keeps a record of people with obstructive sleep apnea (OSA) who also have high blood pressure, to better understand how CPAP is used and what outcomes happen. It may help your care team by contributing your information to a large multi-center study in China.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT04032379Recruiting
Study biomarkers to predict outcomes in idiopathic intracranial hypertension
This study looks at body measurements (“biomarkers”) to help doctors diagnose idiopathic intracranial hypertension (IIH) and predict how it may go over time. If you’re an adult with a doctor’s concern for IIH, you may be asked to provide health information and possibly samples for testing.
Copenhagen, GlostrupAges 18 years+ - NCT05665556Recruiting
Registry for pulmonary hypertension in connective tissue disease
This trial is a registry that collects health information from people with certain types of pulmonary hypertension linked to connective tissue diseases. It helps doctors understand patterns of disease and outcomes, which can guide future care and studies.
Mexico CityAges 18 years+ - NCT05563337Recruiting
Renal denervation for young women with high blood pressure
This study tests a procedure called renal denervation to help lower blood pressure in young women with high blood pressure that’s not too severe. The goal is to see if the treatment can improve blood pressure control safely.
BordeauxAges 18–40 - NCT03169010Recruiting
Study registry for rare lung artery blood pressure problems
This study collects information from people with rare types of pulmonary hypertension (high blood pressure in the lungs) and from healthy volunteers. It helps researchers better understand these conditions, especially using a special lung-heart test to confirm the diagnosis.
Beijing, Beijing MunicipalityAges Any age - NCT05995106Recruiting
Mobile app for high blood pressure in pregnancy
This study tests a mobile health app to help manage high blood pressure during pregnancy. It's for pregnant women 18+ with high blood pressure or at high risk, who can use a smartphone.
Seongnam-si, Gyeonggi-doAges 18 years+ - NCT05726916RecruitingPhase 3
Eculizumab for severe kidney and blood clotting emergencies in adults
This trial studies eculizumab, a targeted blood-clotting and immune system medicine, for adults hospitalized with hypertensive emergency–associated hemolytic uremic syndrome (a serious condition affecting kidneys and blood). It aims to see whether the drug can improve outcomes after this life-threatening event.
ParisAges 18 years+ - NCT06135909Recruiting
CHASE registry for pulmonary hypertension patients on treatment
This study is a registry that collects information on people with pulmonary hypertension who are using or starting targeted medications. The goal is to understand how these treatments work in real-world settings and improve care for patients like you.
BeijingAges 18–85 - NCT05311072Recruiting
Update a CTEPH patient database in China
This study helps doctors update and improve how they understand chronic thromboembolic pulmonary hypertension (CTEPH) in patients in China. It likely involves sharing your medical information (not a new drug) and confirming your diagnosis details to support future research.
BeijingAges 14 years+ - NCT07874191Recruiting
Eye blood flow study in pregnant women with preeclampsia
This study uses a special eye scan to compare blood flow in the back of the eye between pregnant women with preeclampsia, healthy pregnant women, and healthy non-pregnant women. The goal is to see if preeclampsia affects eye blood vessels, which might help with early detection.
Muğla, MenteşeAges 18–45 - NCT05841615Recruiting
Atrial fibrillation and high blood pressure ablation plus kidney nerve treatment
This trial tests whether treating atrial fibrillation with a catheter procedure plus treating high blood pressure through kidney nerve treatment works better together. It may help control rhythm and blood pressure, but you must meet several heart, kidney-artery, and safety requirements.
Xiamen, FujianAges 18–75 - NCT06160921Recruiting
Predicting high blood pressure outcomes
This study is building a tool to predict how high blood pressure (primary hypertension) may progress over time. Researchers at Xinjiang Medical University will use health information from patients to create this model, which could help doctors tailor treatment.
Ürümqi, XinjiangAges Any age - NCT05638503Recruiting
Study of heart changes in people with hypertension
This study looks at new ways to measure heart structure and heart pumping function in people with high blood pressure. The results may help doctors better understand heart changes over time and improve care.
Jinan, ShandongAges 30–75
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Common questions
- Are there clinical trials for high blood pressure?
- Yes. Clin2 currently lists 980 recruiting high blood pressure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high blood pressure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.