Clinical trials
High blood pressure clinical trials
Persistently raised blood pressure, a major risk factor for heart disease and stroke. We’re tracking 988 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07243886Recruiting
Mobile app for high blood pressure or diabetes in pregnancy
This study tests whether a mobile app can help monitor your blood pressure or blood sugar during pregnancy if you have high blood pressure or diabetes. It aims to make it easier to manage your condition and stay connected with your healthcare team.
BiratnagarAges 18 years+ - NCT06770023RecruitingPhase 1
Bridge to lung transplant with ECMO for right heart failure
This study tests a special heart-lung support machine (ECMO) for people waiting for a lung transplant whose heart is failing due to high blood pressure in the lungs. The machine helps rest the heart and lungs until transplant surgery.
Jacksonville, FloridaAges 18–80 - NCT07036510RecruitingPhase 1/Phase 2
Safety and effectiveness of a timolol eye implant for glaucoma patients having cataract surgery
This trial tests a sustained-release implant that delivers timolol, a medicine to lower eye pressure, for people with glaucoma or high eye pressure who are also having cataract surgery. The implant is placed during surgery and may provide long-term pressure control without daily eye drops.
Panama CityAges 40 years+ - NCT07543120RecruitingPhase 2
Extended Safety Study of QCZ484 Blood Pressure Medication
This is a continuation study for people who completed a previous QCZ484 trial and tolerated it well. Researchers will monitor how safe and effective the medication remains with longer-term use for managing high blood pressure.
Garden Grove, CaliforniaAges 18 years+ - NCT03945305Recruiting
Remote ischemic conditioning for high blood pressure
This trial tests if a simple, non-invasive treatment called remote ischemic conditioning (briefly restricting blood flow to an arm) can safely lower blood pressure in people with essential hypertension. It is for adults aged 30-75 whose blood pressure is consistently high despite standard care.
Changchun, JilinAges 30–75 - NCT07728630Recruiting
Blood Vessel Health in Newly Diagnosed Hypertension
This study looks at tiny particles from blood vessel cells to understand early changes in people with newly diagnosed high blood pressure. It compares people with normal blood pressure and those with high blood pressure who have never been treated.
OsijekAges 18 years+ - NCT07473700RecruitingPhase 2
Study of TX000045 for lung scarring and high blood pressure in the lungs
This trial tests a new medicine called TX000045 for people who have both lung scarring (interstitial lung disease) and high blood pressure in the lungs (pulmonary hypertension). It aims to see if the drug can help improve breathing and daily function.
Phoenix, ArizonaAges 18–80 - NCT06843577Recruiting
Handgrip therapy for high blood pressure
This trial tests if a simple handgrip exercise device can help lower blood pressure in people with elevated blood pressure or hypertension. You will use the device at home and have regular check-ups to see how well it works.
Valley Village, CaliforniaAges 22 years+ - NCT07561034Recruiting
Home Exercise Program for Pulmonary Hypertension and Lung Disease
This study tests whether daily home exercises can help people with pulmonary hypertension (high blood pressure in the lungs) combined with interstitial lung disease (scarring of lung tissue). Researchers will send you daily messages to support your exercise routine and see if it improves your symptoms and quality of life.
Rochester, New YorkAges 18 years+ - NCT07644364RecruitingPhase 1
Blood Pressure Medication Study for Japanese Adults
This early-stage trial tests a new blood pressure medication called HJB647 in Japanese adults with elevated or high blood pressure. The study aims to see if the drug is safe and how the body handles it.
Sumida Ku, TokyoAges 18–60 - NCT07713914RecruitingPhase 4
Triple therapy vs sildenafil dose increase for PAH
This study compares two approaches for people with PAH whose current treatment (a combination of sildenafil and an endothelin receptor antagonist) needs to be stepped up. Half the participants will add a third medicine (iloprost or selexipag), while the other half will increase their sildenafil dose. The goal is to see which strategy works better for improving symptoms and lowering risk.
São Paulo, São PauloAges 18 years+ - NCT07420465Recruiting
Heart and metabolic risks in pregnancy and after birth
This study looks at heart and metabolic health during late pregnancy and after delivery, tracking both healthy women and those with complications like high blood pressure or diabetes in pregnancy. The goal is to understand how these risks change and what can be done to improve long-term health.
AccraAges 18–45 - NCT02966665RecruitingPhase 1
Testing blood vessel function in people of different health conditions
This early study measures how well your blood vessels work using tests that may include MRI. It compares healthy people with people who have conditions like COPD, pulmonary arterial hypertension, heart failure, or high blood pressure, to better understand “vascular function” in health and disease.
Salt Lake City, UtahAges 18 years+ - NCT03042988Recruiting
Heat stress test in people with low nerve control and high blood pressure
This study checks how your body’s blood pressure and stress responses change after being exposed to heat overnight. It’s meant for people with autonomic failure (like certain Parkinson-related or nerve-function conditions) who also have high blood pressure while lying down, which may help researchers understand safer ways to manage it.
Nashville, TennesseeAges 18–80 - NCT03169010Recruiting
Study registry for rare lung artery blood pressure problems
This study collects information from people with rare types of pulmonary hypertension (high blood pressure in the lungs) and from healthy volunteers. It helps researchers better understand these conditions, especially using a special lung-heart test to confirm the diagnosis.
Beijing, Beijing MunicipalityAges Any age - NCT03269630Recruiting
Pulmonary hypertension biobank for heart-lung blood samples
This study collects and stores health information and possibly blood samples from people being evaluated for pulmonary hypertension or related autoimmune conditions. It helps researchers learn more about these illnesses and may support future studies.
New Orleans, LouisianaAges 18 years+ - NCT03312556Recruiting
CPAP for high blood pressure when lying down
This trial looks at whether using CPAP (a breathing device) can help control high blood pressure that happens when you lie down, in people with autonomic failure. It’s designed for safety and effectiveness and may improve symptoms and blood pressure control.
Nashville, TennesseeAges 18–85 - NCT03755726Recruiting
Study of care for dangerously high blood pressure
This trial looks at a health-care plan for people with malignant hypertension (very high blood pressure causing emergency eye and organ damage). It may help doctors better organize treatment and follow-up after this high-risk diagnosis.
AnnecyAges 18 years+ - NCT03762499Recruiting
Personalized blood pressure care for young adults using heart ultrasound
This study looks at a personalized approach to managing high blood pressure in adults aged 18–40, using heart ultrasound information along with regular clinical checkups. It may help clinicians tailor treatment to each person’s heart-related findings.
OxfordAges 18–40 - NCT03959748Recruiting
Pulmonary hypertension patients’ heart-lung pressure database study
This study builds a database of people with pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension. It may help doctors better understand these conditions in the Polish population and improve future care decisions.
KrakowAges 3 months+ - NCT04032379Recruiting
Study biomarkers to predict outcomes in idiopathic intracranial hypertension
This study looks at body measurements (“biomarkers”) to help doctors diagnose idiopathic intracranial hypertension (IIH) and predict how it may go over time. If you’re an adult with a doctor’s concern for IIH, you may be asked to provide health information and possibly samples for testing.
Copenhagen, GlostrupAges 18 years+ - NCT04078243Recruiting
Trial setup and testing in adults with pulmonary hypertension
This study tests new “trial tools” and designs for running early research in people with pulmonary hypertension. If you qualify, you may be asked to do extra trial-related procedures to help researchers test the process safely and smoothly.
Sheffield, South YorkshireAges 18 years+ - NCT04126785Recruiting
Exercise program for older adults with controlled high blood pressure
This trial compares two types of water-based exercise—short, intense bursts versus a steady, moderate pace—in older adults with high blood pressure that is already being controlled. It may help determine which exercise style lowers blood pressure and is easier or safer to stick with.
Bauru, São PauloAges 60 years+ - NCT04145024Recruiting
Pulmonary hypertension registry and blood sample biobank
This study keeps a health registry and biobank for people diagnosed with pulmonary hypertension using a specific heart test. It helps researchers better understand the condition and may improve future care.
GiessenAges Any age
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Common questions
- Are there clinical trials for high blood pressure?
- Yes. Clin2 currently lists 988 recruiting high blood pressure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high blood pressure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.