Clinical trials
High blood pressure clinical trials
Persistently raised blood pressure, a major risk factor for heart disease and stroke. We’re tracking 980 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07747025Recruiting
Nurse-led talks to help control blood pressure
This study tests whether talking with a nurse can help you manage your blood pressure better. You'll have support from a family member and learn ways to keep your blood pressure in a healthy range.
SimavAges 18 years+ - NCT05845905Recruiting
Remote arm treatment to lower blood pressure in older adults
This study tests whether a simple “remote conditioning” method done on the arm can help lower blood pressure in older adults with hypertension. It may help people whose blood pressure is high but not dangerously high at the time of screening.
Changchun, JilinAges 65–85 - NCT07728630Recruiting
Blood Vessel Health in Newly Diagnosed Hypertension
This study looks at tiny particles from blood vessel cells to understand early changes in people with newly diagnosed high blood pressure. It compares people with normal blood pressure and those with high blood pressure who have never been treated.
OsijekAges 18 years+ - NCT06635603Recruiting
Atmospheric pressure and hypertensive crisis study
This study looks at whether changes in atmospheric pressure (the weight of the air) are linked to very high blood pressure emergencies. You may be able to join if you come to the emergency room with a hypertensive crisis but without organ damage.
AnkaraAges 18 years+ - NCT05745961Recruiting
Measuring a lung protein in pulmonary artery hypertension
This study measures how much of a specific lung protein (TSPO) is present in people with pulmonary artery hypertension. The results may help researchers better understand the disease and guide future treatments.
LondonAges 25–75 - NCT07713914RecruitingPhase 4
Triple therapy vs sildenafil dose increase for PAH
This study compares two approaches for people with PAH whose current treatment (a combination of sildenafil and an endothelin receptor antagonist) needs to be stepped up. Half the participants will add a third medicine (iloprost or selexipag), while the other half will increase their sildenafil dose. The goal is to see which strategy works better for improving symptoms and lowering risk.
São Paulo, São PauloAges 18 years+ - NCT05039684Recruiting
Testing eye-surface inflammation in glaucoma or high eye pressure
This study measures inflammation markers on the eye surface in people with primary open-angle glaucoma or ocular hypertension who use certain glaucoma drops. The results may help doctors understand how these drops affect the eye and inflammation.
ValladolidAges 18–99 - NCT07675824RecruitingPhase 1/Phase 2
New treatment for open-angle glaucoma or high eye pressure
This trial tests an investigational drug called REGN22530 for people with mild to moderate primary open-angle glaucoma or ocular hypertension (high eye pressure). The goal is to see if it can safely lower eye pressure and protect vision.
Deerfield Beach, FloridaAges 18 years+ - NCT07661329RecruitingPhase 3
Comparing a new eye drop to a standard one for glaucoma and high eye pressure
This study tests a new eye drop against an existing one to see which better lowers eye pressure in people with open-angle glaucoma or ocular hypertension. You may be able to join if you have high eye pressure in both eyes that needs treatment and you are at least 18 years old.
Beverly Hills, CaliforniaAges 18 years+ - NCT07662759RecruitingPhase 3
Study of TFC-003 for open-angle glaucoma or high eye pressure
This trial tests a new eye drop combination (TFC-003) to lower eye pressure in people with primary open-angle glaucoma or ocular hypertension. It compares the new drug to existing treatments to see if it works better or is safer.
SeongnamAges 19 years+ - NCT06678698Recruiting
Light therapy for blood pressure control in adults
This trial tests light therapy (photobiomodulation) to see if it helps people with high blood pressure who still have trouble controlling it with medication. It is a short study looking at an acute effect.
São Carlos, São PauloAges 40–60 - NCT07646860RecruitingPhase 2
Sotatercept for Japanese Children With Pulmonary Arterial Hypertension
This study tests a new medicine called sotatercept in Japanese children who have pulmonary arterial hypertension (PAH)—a condition where blood vessels in the lungs become narrow and stiff, making it harder for the heart to pump blood through them. The medicine may help improve how well their hearts and lungs work together.
Izumi, OsakaAges 1–17 - NCT07654140RecruitingPhase 2
Testing a new drug for uncontrolled high blood pressure
This trial tests a new drug called SAL0140 for people whose high blood pressure is not controlled by current treatments. It may help lower blood pressure when other medications haven't worked well enough.
Beijing, Beijing MunicipalityAges 18–75 - NCT07644364RecruitingPhase 1
Blood Pressure Medication Study for Japanese Adults
This early-stage trial tests a new blood pressure medication called HJB647 in Japanese adults with elevated or high blood pressure. The study aims to see if the drug is safe and how the body handles it.
Sumida Ku, TokyoAges 18–60 - NCT05590871Recruiting
Kidney nerve ablation to treat hard-to-control blood pressure
This trial tests a procedure that targets nerves near the kidney (renal denervation) to help lower blood pressure in people whose hypertension is not controlled despite medication. It uses a special 3D mapping system to guide the procedure.
Chongqing, Chongqing MunicipalityAges 18–70 - NCT06640751Recruiting
Helping people with hypertension improve health habits
This study tests whether a program to support healthy behaviors can help people with high blood pressure better control their condition. It is for people whose blood pressure is not well managed or who find it hard to stick with treatment.
Nanjing, JiangsuAges 18–80 - NCT04898114RecruitingPhase 1/Phase 2
Inhaled magnesium and sildenafil for newborn lung blood pressure
This study tests whether breathing in magnesium sulfate and giving sildenafil can improve breathing and lung blood vessel pressure in newborns with persistent pulmonary hypertension. It may help newborns who are having trouble oxygenating despite being on a ventilator.
SohagAges 6 hours–3 days - NCT07606768Enrolling by invitation
Nurse coaching to help control high blood pressure
This study tests whether regular phone or video coaching from a nurse helps people with high blood pressure better manage their condition and take their medications. You'll receive personalized guidance to improve your health habits and blood pressure control.
Huayuan, HunanAges 18–85 - NCT07606859Recruiting
Heat and Air Pollution Reduction for Older Adults With High Blood Pressure
This study tests whether reducing exposure to heat and air pollution helps older adults with high blood pressure feel better and stay healthier. Researchers will provide tools and support to help you stay cool and breathe cleaner air at home.
NicosiaAges 65 years+ - NCT05986487Recruiting
Sleep apnea treatment for better blood pressure control
This trial tests whether treating sleep-disordered breathing (like sleep apnea) can help lower blood pressure in people with high blood pressure. You may join if you have high blood pressure and haven't been diagnosed with a sleep disorder before.
LleidaAges 18 years+ - NCT07603583Recruiting
Heart Rate Variability to Detect Sleep Apnea in Hypertension
This study tests whether a simple heart-rate measurement can help detect obstructive sleep apnea (a breathing condition during sleep) in people with high blood pressure. The goal is to find an easier way to screen for sleep apnea, which often goes undiagnosed but can worsen heart health.
Kaohsiung City, KaohsiungAges 18–65 - NCT07596966Recruiting
Propolis and Royal Jelly for High Blood Pressure
This study tests whether two bee products—propolis and royal jelly—can help reduce inflammation and stress in the body of people with high blood pressure. Researchers want to see if adding these supplements to your current blood pressure medication helps control the condition better.
Niterói, Rio de JaneiroAges 18–75 - NCT07588152RecruitingPhase 4
How Netarsudil Eye Drops Affect the Eye's Drain System
This study uses special imaging to see how the eye-pressure-lowering medication netarsudil (Rhopressa) works on the part of your eye that drains fluid. Researchers want to understand whether it helps restore normal drainage in people with high eye pressure or glaucoma.
Bloomington, IndianaAges 18 years+ - NCT07594808Enrolling by invitationPhase 2
Stress Management App for African American Men with High Blood Pressure
This study tests a mobile stress-management app to help African American men lower their blood pressure. If you have high blood pressure and a smartphone, you may be able to take part from home.
Washington D.C., District of ColumbiaAges 18 years+
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Common questions
- Are there clinical trials for high blood pressure?
- Yes. Clin2 currently lists 980 recruiting high blood pressure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high blood pressure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.