Clinical trials
Hyperuricemia or Gout clinical trials
Below are recruiting hyperuricemia or gout clinical trials, each written for real people, not researchers. We’re tracking 56 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07535034RecruitingPhase 2
Testing Dotinurad for Gout in People Who Can't Take Other Medications
This trial tests a new drug called dotinurad for gout patients whose standard medications either don't work or cause side effects. Dotinurad works differently by helping your body get rid of uric acid (the substance that causes gout attacks), and the study will see if it safely lowers uric acid levels.
Granada Hills, CaliforniaAges 18–75 - NCT04875702RecruitingPhase 4
Compare urate targets to reduce gout attacks or symptoms
This study compares two different treatment goals for a blood level called urate in people with gout. The goal is to see which approach lowers gout flares better while helping people feel better.
South Birmingham, AlabamaAges 18–90 - NCT05546593Recruiting
Ultrasound check for joint and tendon problems in gout
This study uses ultrasound to look for hidden changes in joints and tendons in people who have gout. It may help doctors better understand what ultrasound can show in gout, but it doesn’t sound like it’s testing a new medicine.
Boulogne-Billancourt, APHPAges 18 years+ - NCT05927688Recruiting
Using patient reports to adjust treatment for autoimmune diseases
This study looks at whether doctors consider patient “electronic reports” (completed online/phone) when deciding how often to change treatment. It may help improve how well treatment plans match how patients feel over time.
StrasbourgAges 18 years+ - NCT06298071RecruitingPhase 1
Peguricase with methotrexate for uncontrolled gout
This early-phase trial tests a new injectable medication (Peguricase) combined with methotrexate to lower uric acid in people with gout that standard pills haven't controlled. You would first take a low dose of methotrexate to check your tolerance, then receive Peguricase infusions while stopping your usual gout medications.
Bengbu, AnhuiAges 18–70 - NCT06310967RecruitingPhase 1/Phase 2
Study of IG3018 for high uric acid with or without kidney disease
This trial tests a new medicine, IG3018, to lower high uric acid levels in people with or without chronic kidney disease. It aims to find the right dose and see if it's safe.
Botany, New South WalesAges 18–75 - NCT06463561RecruitingPhase 4
CPAP for high cholesterol and sleep apnea
This study tests if CPAP therapy can improve cholesterol and uric acid levels in people with both high cholesterol and moderate to severe sleep apnea. It may help if you have sleep apnea and are looking for additional ways to manage your lipid levels.
Coslada, MadridAges 35–80 - NCT06534554Recruiting
Improving gout care after an emergency room visit
This study looks at ways to improve how gout is managed after a visit to the emergency room. It aims to help you get better follow-up care and prevent future flares.
Birmingham, AlabamaAges 18–99 - NCT06622603RecruitingPhase 4
Testing lower doses of febuxostat in well-controlled gout
This trial tests if gradually lowering the dose of the gout medication febuxostat is safe for people whose gout has been well-controlled for at least 5 years. The goal is to see if a lower dose can still keep uric acid levels in a healthy range.
Seongnam-si, Gyeonggi-doAges 19–79 - NCT07280156RecruitingPhase 2
Study of PRX-115 for gout with or without methotrexate
This trial tests a new medicine, PRX-115, given through a vein, to see if it lowers uric acid levels in people with gout who haven't had success with standard treatments. Some participants will also take methotrexate, and the results are compared to a placebo (a dummy infusion).
Little Rock, ArkansasAges 18 years+ - NCT07343336Recruiting
Study of gout in French Polynesia
This study looks at gout in people of Polynesian ancestry to learn more about its causes and how it affects people. It may help improve diagnosis and treatment for this community.
Faa'aAges 18–75 - NCT07400549Recruiting
Exercise plan study for people with high blood pressure, blood sugar, cholesterol, or uric acid
This study tests a tool that helps doctors create personalized exercise plans for people with conditions like high blood pressure, diabetes, high cholesterol, or high uric acid (the "Four Highs"). It could help you stay active and manage your health better.
BeijingAges 18 years+ - NCT07414394RecruitingPhase 3
Tigulixostat vs febuxostat for gout patients
This trial tests a new medicine called tigulixostat against febuxostat, a standard gout treatment, to see which works better at lowering uric acid levels. You may qualify if you have gout with high uric acid and have not had a gout flare in the last month.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07490522Recruiting
Remote monitoring for gout in primary care
This study tests whether a smartphone app can help your doctor monitor your gout and adjust your urate-lowering medication. It is a feasibility study, meaning it checks if the approach works well for patients.
OsloAges 18 years+ - NCT07666126Recruiting
Uric acid and gum bone health study
This study looks at whether high uric acid levels affect the bone around your teeth. If you are between 18 and 65, have at least 20 natural teeth, and are either healthy or have high uric acid and gum disease, this trial may be for you.
RizeAges 18–65 - NCT07001865Enrolling by invitation
Effects of healthy obesity on liver and uric acid risks
This study looks at people who are metabolically healthy but overweight or obese, and how that affects their risk of developing fatty liver disease (MASLD) or high uric acid levels (hyperuricemia). It aims to see if 'healthy' obesity still carries hidden health risks.
NingboAges 18–100 - NCT06822933Enrolling by invitation
Remote monitoring study for gout patients
This study tests whether using a smartphone or tablet to monitor your gout from home can help manage the condition. You may qualify if you have had at least one gout flare in the last year and have high uric acid levels.
Oslo, Please SelectAges 18 years+ - NCT06981663Recruiting
Fibers and probiotics for uric acid levels
This study looks at how certain fibers and probiotics might affect uric acid levels in your body. You'll provide a stool sample, and it will be tested in a lab to see if these ingredients can help lower uric acid.
ÖrebroAges 18–80 - NCT03524222Recruiting
Home hospital care for adults after sudden illness
This trial tests whether certain adults can safely receive hospital-level care at home instead of staying in the hospital, using a home care team. It may help you recover in your own home if your condition fits their plan and you have support at home.
Boston, MassachusettsAges 18 years+ - NCT04695028Recruiting
Study to better understand crystal-related joint pain
This study looks at people with certain types of crystal deposits in joints (like gout, CPPD, or hydroxyapatite crystal disease). It uses scans such as ultrasound and a special CT-type scan called DECT to confirm and better understand what’s causing your symptoms.
LommeAges 18 years+ - NCT05109936RecruitingPhase 3
Febuxostat given right away versus later for gout flare
This Phase 3 study compares starting febuxostat immediately during a gout flare versus delaying the start. It aims to see which timing helps control gout better and safely.
CaenAges 18 years+ - NCT05476627Recruiting
Study risk factors for kidney disease from metabolic conditions
This study looks at risk factors and body “omics” information (like blood/tissue patterns) to better understand chronic kidney disease caused by metabolic diseases. It may help researchers find better ways to predict or manage kidney problems in people with these conditions.
Beijing, Beijing MunicipalityAges 18–80 - NCT05507723Recruiting
Smartphone-guided tight gout control vs usual care
This study tests whether a “tighter” gout treatment plan guided through a smartphone app can reduce gout flare-ups compared with usual care. It may help people whose uric acid levels are still high despite treatment.
EdinburghAges 18 years+ - NCT06092346Recruiting
Understanding rare purine and pyrimidine metabolism disorders
This study aims to learn more about rare disorders of purine and pyrimidine metabolism (DPPM), which can affect the brain, immune system, kidneys, and muscles. Researchers will study people with these disorders, their family members, and healthy volunteers to better understand the condition over time.
Bethesda, MarylandAges 1 month–100 years
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Common questions
- Are there clinical trials for hyperuricemia or gout?
- Yes. Clin2 currently lists 56 recruiting hyperuricemia or gout studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hyperuricemia or gout trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hyperuricemia or gout trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.