Clinical trials
Hyperuricemia or Gout clinical trials
Below are recruiting hyperuricemia or gout clinical trials, each written for real people, not researchers. We’re tracking 54 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07400549Recruiting
Exercise plan study for people with high blood pressure, blood sugar, cholesterol, or uric acid
This study tests a tool that helps doctors create personalized exercise plans for people with conditions like high blood pressure, diabetes, high cholesterol, or high uric acid (the "Four Highs"). It could help you stay active and manage your health better.
BeijingAges 18 years+ - NCT07388498RecruitingPhase 3
Study of pegloticase with methotrexate for uncontrolled gout
This trial tests a new way of giving pegloticase (a drug that breaks down uric acid) by injection under the skin, combined with methotrexate, to see if it works better for people with uncontrolled gout. It might help if you have painful flares that don't go away with usual treatments.
Birmingham, AlabamaAges 18 years+ - NCT07343336Recruiting
Study of gout in French Polynesia
This study looks at gout in people of Polynesian ancestry to learn more about its causes and how it affects people. It may help improve diagnosis and treatment for this community.
Faa'aAges 18–75 - NCT05927688Recruiting
Using patient reports to adjust treatment for autoimmune diseases
This study looks at whether doctors consider patient “electronic reports” (completed online/phone) when deciding how often to change treatment. It may help improve how well treatment plans match how patients feel over time.
StrasbourgAges 18 years+ - NCT05546593Recruiting
Ultrasound check for joint and tendon problems in gout
This study uses ultrasound to look for hidden changes in joints and tendons in people who have gout. It may help doctors better understand what ultrasound can show in gout, but it doesn’t sound like it’s testing a new medicine.
Boulogne-Billancourt, APHPAges 18 years+ - NCT07280156RecruitingPhase 2
Study of PRX-115 for gout with or without methotrexate
This trial tests a new medicine, PRX-115, given through a vein, to see if it lowers uric acid levels in people with gout who haven't had success with standard treatments. Some participants will also take methotrexate, and the results are compared to a placebo (a dummy infusion).
Glendale, ArizonaAges 18 years+ - NCT06824376Recruiting
Acupuncture for high uric acid without gout
This trial tests if manual acupuncture can safely lower uric acid in people who have high levels but have never had a gout attack. It aims to find a drug-free way to manage hyperuricemia before it causes joint problems.
Wuhan, HubeiAges 18 years+ - NCT07089888RecruitingPhase 3
Dotinurad vs allopurinol for gout with lumps
This trial is testing a new gout medication, dotinurad, compared to the standard treatment allopurinol for people with tophaceous gout (gout that causes hard lumps). It aims to see if dotinurad is better at reducing uric acid and shrinking those lumps.
Birmingham, AlabamaAges 18–75 - NCT07089875RecruitingPhase 3
Testing dotinurad vs allopurinol for people with gout
This study compares a new gout medicine called dotinurad to the common medicine allopurinol. It is for people who have had gout for at least a year, have had at least 2 gout attacks in the last year, and are already taking a stable dose of allopurinol but still have high uric acid levels.
Birmingham, AlabamaAges 18–75 - NCT07001865Enrolling by invitation
Effects of healthy obesity on liver and uric acid risks
This study looks at people who are metabolically healthy but overweight or obese, and how that affects their risk of developing fatty liver disease (MASLD) or high uric acid levels (hyperuricemia). It aims to see if 'healthy' obesity still carries hidden health risks.
NingboAges 18–100 - NCT06859073RecruitingPhase 1
Safety study of NNC4004-0002 for high uric acid without symptoms
This study tests a new medicine, NNC4004-0002, for people who have high uric acid levels but no gout symptoms. The goal is to see if it is safe and how well it works in healthy adults aged 35 to 75.
Glendale, CaliforniaAges 35–75 - NCT06822933Enrolling by invitation
Remote monitoring study for gout patients
This study tests whether using a smartphone or tablet to monitor your gout from home can help manage the condition. You may qualify if you have had at least one gout flare in the last year and have high uric acid levels.
Oslo, Please SelectAges 18 years+ - NCT06622603RecruitingPhase 4
Testing lower doses of febuxostat in well-controlled gout
This trial tests if gradually lowering the dose of the gout medication febuxostat is safe for people whose gout has been well-controlled for at least 5 years. The goal is to see if a lower dose can still keep uric acid levels in a healthy range.
Seongnam-si, Gyeonggi-doAges 19–79 - NCT06534554Recruiting
Improving gout care after an emergency room visit
This study looks at ways to improve how gout is managed after a visit to the emergency room. It aims to help you get better follow-up care and prevent future flares.
Birmingham, AlabamaAges 18–99 - NCT06298071RecruitingPhase 1
Peguricase with methotrexate for uncontrolled gout
This early-phase trial tests a new injectable medication (Peguricase) combined with methotrexate to lower uric acid in people with gout that standard pills haven't controlled. You would first take a low dose of methotrexate to check your tolerance, then receive Peguricase infusions while stopping your usual gout medications.
Bengbu, AnhuiAges 18–70 - NCT06310967RecruitingPhase 1/Phase 2
Study of IG3018 for high uric acid with or without kidney disease
This trial tests a new medicine, IG3018, to lower high uric acid levels in people with or without chronic kidney disease. It aims to find the right dose and see if it's safe.
Botany, New South WalesAges 18–75 - NCT04875702RecruitingPhase 4
Compare urate targets to reduce gout attacks or symptoms
This study compares two different treatment goals for a blood level called urate in people with gout. The goal is to see which approach lowers gout flares better while helping people feel better.
South Birmingham, AlabamaAges 18–90 - NCT05476627Recruiting
Study risk factors for kidney disease from metabolic conditions
This study looks at risk factors and body “omics” information (like blood/tissue patterns) to better understand chronic kidney disease caused by metabolic diseases. It may help researchers find better ways to predict or manage kidney problems in people with these conditions.
Beijing, Beijing MunicipalityAges 18–80 - NCT04695028Recruiting
Study to better understand crystal-related joint pain
This study looks at people with certain types of crystal deposits in joints (like gout, CPPD, or hydroxyapatite crystal disease). It uses scans such as ultrasound and a special CT-type scan called DECT to confirm and better understand what’s causing your symptoms.
LommeAges 18 years+ - NCT07504146Recruiting
The Orienting study: imaging in CPPD, gout, and OA
This study looks at imaging findings (ultrasound and X-rays) in people with CPPD, gout, or osteoarthritis. It aims to help doctors better identify these conditions early.
Milan, MilanoAges 18 years+ - NCT07310849Recruiting
Digital health support for older adults with diabetes
This study tests a digital care program using the LINE messaging app to help older adults with diabetes and other chronic conditions manage their health. It may be a good fit if you are 50 or older, have type 2 diabetes plus another condition like high blood pressure, and are comfortable using a smartphone.
New Taipei City, Wugu DistrictAges 50 years+ - NCT07150000Recruiting
Rheumatic disease research study for patients and healthy volunteers
This study is for people with certain rheumatic conditions (like arthritis, lupus, or vasculitis) and for healthy volunteers. It aims to learn more about these diseases and improve how they are treated.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT07144332Recruiting
Does dialysis alone lower uric acid enough?
This study checks how well hemodialysis alone removes uric acid from the blood. It helps doctors decide if extra medicines are needed to lower uric acid in people on regular dialysis.
SohagAges 18 years+ - NCT06981663Recruiting
Fibers and probiotics for uric acid levels
This study looks at how certain fibers and probiotics might affect uric acid levels in your body. You'll provide a stool sample, and it will be tested in a lab to see if these ingredients can help lower uric acid.
ÖrebroAges 18–80
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Common questions
- Are there clinical trials for hyperuricemia or gout?
- Yes. Clin2 currently lists 54 recruiting hyperuricemia or gout studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hyperuricemia or gout trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hyperuricemia or gout trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.