Clinical trials
Immune System clinical trials
Below are recruiting immune system clinical trials, each written for real people, not researchers. We’re tracking 130 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06787560RecruitingEarly Phase 1
CAR-T cells and stem cell transplant for blood diseases
This trial tests a new approach for people with non-cancerous blood and immune system diseases. It uses your own engineered immune cells (CAR-T cells) to prepare your body for a stem cell transplant from a relative.
Hangzhou, ZhejiangAges Any age - NCT06826066Recruiting
How your immune system reacts to radiation therapy
This study looks at how your immune system affects how your body reacts to radiation therapy. It involves a blood sample and is for people who have had radiation but no major side effects.
Créteil, Île-de-France RegionAges 18 years+ - NCT07273344Recruiting
How the immune system responds to sepsis
This study looks at how the immune system reacts to sepsis (a severe infection that causes organs to fail) and whether there are lasting effects on health. It may help researchers understand why some people recover well and others don’t.
Nijmegen, GelderlandAges 18 years+ - NCT07314359Recruiting
Study of a biofield patch on antioxidants and energy
This study tests a special patch (called a biofield patch) to see if it can improve your body's antioxidant levels and energy. It involves several clinic visits with blood draws over a short time period.
Klamath Falls, OregonAges 18–75 - NCT00001979Recruiting
Understanding Immune System Kidney Disease
This research study looks at kidney diseases caused by the immune system—conditions where your body's defense system mistakenly attacks the kidneys. Researchers will study your medical history, blood, and urine to better understand these diseases and potentially improve treatment.
Bethesda, MarylandAges 10–99 - NCT00001406Recruiting
Understanding eosinophil behavior in rare blood and tissue conditions
This research study examines how eosinophils (a type of white blood cell) behave and function when they become abnormally high in the blood or tissues. Researchers want to understand these conditions better to potentially improve treatment options.
Bethesda, MarylandAges 1–100 - NCT01503190Recruiting
Study of how breast cancer affects the immune system
This study looks at how the immune system changes in people with breast cancer, using patient tissue samples. It may help researchers understand immune responses in young women and guide future cancer treatments.
Aurora, ColoradoAges 18 years+ - NCT00006150Recruiting
Understanding Hyper-IgE Syndrome: Natural History and Genetics
This study follows people with or suspected Hyper-IgE syndrome (a rare immune disorder causing repeated infections and skin problems) to understand how the condition develops, how best to manage it, and which genes are involved. Researchers also welcome healthy relatives of patients to help identify genetic patterns.
Bethesda, MarylandAges 1 month–120 years - NCT01568697Recruiting
Studying gum disease in people with immune and genetic differences
This study looks at how mouth bacteria and the immune system may work together to cause gum disease (periodontitis), especially in people with certain genetic immune problems. It may help researchers understand what drives severe gum disease and how to better monitor or treat it in the future.
Bethesda, MarylandAges 7–100 - NCT01351545Recruiting
Cryopreserved cord blood access program for transplant patients
This trial studies an organized way to obtain and distribute unlicensed (not FDA-approved for general use) stored cord blood units that have been frozen and kept. It may help people who need a cord blood transplant but don’t fit the “licensed cord blood only” options.
Birmingham, AlabamaAges Any age - NCT02579967RecruitingPhase 2
Stem cell transplant for primary immune system disorders
This study tests whether an allogeneic stem cell (bone marrow) transplant can correct an inherited immune problem in people with severe primary immunodeficiencies. It may help reduce life-threatening infections and improve quality of life, depending on your overall health and donor match.
Bethesda, MarylandAges 4–75 - NCT02869048Recruiting
Study blood and immune signals in ALS and healthy controls
This trial studies the “innate immune system” (your body’s first-line immune response) in people with ALS and in comparison groups. It may help researchers understand what drives ALS and how immune changes could relate to symptoms.
AarhusAges 18 years+ - NCT07416201Recruiting
Study of Immune System Aging in Down Syndrome
This study is looking at how the immune system changes over time in people with Down syndrome, and how it may be affected by removal of the thymus gland. The goal is to understand why people with Down syndrome may age faster or have different immune health.
Bethesda, MarylandAges 1–120 - NCT07463196RecruitingPhase 1
Safety study of ACI-19764 in healthy adults
This trial tests a new oral medication, ACI-19764, in healthy adults to see how safe it is and how the body processes it. It may help researchers understand how the drug affects the immune system, which could lead to future treatments for certain conditions.
GroningenAges 18–65 - NCT07508319Recruiting
Immune system’s role in preventing laryngeal cancer
This trial studies how the immune system helps prevent laryngeal cancer. It focuses on people with a precancerous condition called laryngeal dysplasia to see if the immune response can stop cancer from developing.
Milan, MIAges 18–99 - NCT07552116Recruiting
Low-intensity laser therapy for pneumonia in children with Down syndrome
This trial tests whether a special low-intensity laser treatment can help boost the immune system and fight pneumonia in children with Down syndrome. Researchers want to see if this approach might help children recover better from their first pneumonia infection.
CairoAges 3–5 - NCT07598643RecruitingPhase 2
Immune System Treatment to Help Down Syndrome Development
This study tests a medication called tofacitinib that modulates the immune system in children and young adults with Down syndrome aged 6–22 years. The goal is to see if it can improve brain development and overall health outcomes over 6 months.
Aurora, ColoradoAges 6–22 - NCT06133530Enrolling by invitation
Human milk sugars for gut health in Antarctica
This study tests whether natural sugars found in human milk (called HMOs) can improve gut health and the immune system. Researchers are looking for healthy adults who are willing to travel to Antarctica for the study.
ErfurtAges 18–65 - NCT05131594Enrolling by invitation
Study immune response in Long COVID patients
This trial studies how your immune system responds in people with Long COVID after a past COVID-19 infection. It may help researchers understand why symptoms linger and how the body’s response could be targeted.
Pasadena, CaliforniaAges 18 years+ - NCT04323566Enrolling by invitationPhase 2
Rituximab for OCD or psychosis linked to immune inflammation
This trial tests rituximab (an immune system medicine) to see if it can reduce OCD symptoms and/or psychosis when there are signs the immune system may be involved. You may be considered if other standard psychiatric treatments have not helped enough and your illness seems relatively recent with possible inflammation clues.
UppsalaAges 18–55 - NCT07348055RecruitingPhase 1/Phase 2
A study of GR1803 for lupus
This trial tests a new drug called GR1803 for people with systemic lupus erythematosus (SLE), an autoimmune disease that causes inflammation. It may help reduce disease activity when standard treatments haven't worked well enough.
Wuhan, HubeiAges 18–60 - NCT07512518Recruiting
Study of Long-Term Viral Brain Infections
This study follows patients with chronic viral infections affecting the brain and spinal cord. Researchers will collect spinal fluid samples and track your health over one year to better understand these infections and improve care.
Beijing, Beijing MunicipalityAges 14 years+ - NCT06829238RecruitingPhase 4
Metformin to boost immune function in people with a history of drug use
This study tests whether metformin, a common diabetes drug, can help restore immune system balance in people who have used injection drugs in the past. It includes both people living with HIV and those who are HIV-negative.
Birmingham, AlabamaAges 18–64 - NCT06685887RecruitingPhase 2
Chemo, Immunotherapy, and Heated Belly Chemo for Stomach Cancer Spread
This trial tests combining standard chemotherapy and immunotherapy (tirelizumab) with heated chemotherapy given directly into the belly. It aims to treat stomach cancer that has spread to the abdominal lining, and may help shrink or control the cancer.
Wuhan, HubeiAges 18–75
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Common questions
- Are there clinical trials for immune system?
- Yes. Clin2 currently lists 130 recruiting immune system studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a immune system trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a immune system trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.