Clinical trials
Immune System clinical trials
Below are recruiting immune system clinical trials, each written for real people, not researchers. We’re tracking 126 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07598643RecruitingPhase 2
Study of tofacitinib for immune function in Down syndrome
This study tests if an oral medication called tofacitinib can help the immune system work better in children and young adults with Down syndrome, which may improve learning and development. The study will follow participants for 6 months.
Aurora, ColoradoAges 6–22 - NCT07552116Recruiting
Low-intensity laser therapy for pneumonia in children with Down syndrome
This trial tests whether a special low-intensity laser treatment can help boost the immune system and fight pneumonia in children with Down syndrome. Researchers want to see if this approach might help children recover better from their first pneumonia infection.
CairoAges 3–5 - NCT07508319Recruiting
Immune system’s role in preventing laryngeal cancer
This trial studies how the immune system helps prevent laryngeal cancer. It focuses on people with a precancerous condition called laryngeal dysplasia to see if the immune response can stop cancer from developing.
Milan, MIAges 18–99 - NCT06787560RecruitingEarly Phase 1
CAR-T cells and stem cell transplant for blood diseases
This trial tests a new approach for people with non-cancerous blood and immune system diseases. It uses your own engineered immune cells (CAR-T cells) to prepare your body for a stem cell transplant from a relative.
Hangzhou, ZhejiangAges Any age - NCT07463196RecruitingPhase 1
Study of ACI-19764 for healthy people and those with heart risks
This trial tests an experimental drug called ACI-19764 to see how safe it is, how the body handles it, and how it affects the immune system. It's for healthy adults and for adults with heart-related risk factors like obesity or type 2 diabetes.
GroningenAges 18–75 - NCT07416201Recruiting
Study of Immune System Aging in Down Syndrome
This study is looking at how the immune system changes over time in people with Down syndrome, and how it may be affected by removal of the thymus gland. The goal is to understand why people with Down syndrome may age faster or have different immune health.
Bethesda, MarylandAges 1–120 - NCT07314359Recruiting
Study of a biofield patch on antioxidants and energy
This study tests a special patch (called a biofield patch) to see if it can improve your body's antioxidant levels and energy. It involves several clinic visits with blood draws over a short time period.
Klamath Falls, OregonAges 18–75 - NCT07273344Recruiting
How the immune system responds to sepsis
This study looks at how the immune system reacts to sepsis (a severe infection that causes organs to fail) and whether there are lasting effects on health. It may help researchers understand why some people recover well and others don’t.
Nijmegen, GelderlandAges 18 years+ - NCT06109337Recruiting
Immune cells in children with ADHD
This study looks at immune system cells in the blood of children with ADHD. It aims to understand how these cells might be different, which could lead to new treatment ideas.
Hangzhou, ZhejiangAges 6–12 - NCT07220915RecruitingPhase 3
Study of Panzyga to prevent infections in people with weak immune systems
This trial tests if a medication called Panzyga can help prevent infections in people with autoimmune conditions who have low antibody levels after B-cell therapy. It may be an option if you have a condition like multiple sclerosis, rheumatoid arthritis, or lupus.
Glendale, ArizonaAges 18 years+ - NCT06286644Recruiting
Hops compounds and your immune system
This study looks at how compounds found in hops (used in beer) affect your immune system. If you are a healthy adult, you may join and help researchers learn more about how these natural substances work.
ViennaAges 18–70 - NCT06745102Recruiting
Hop compounds for immune health in people with extra weight
This trial tests if compounds from hops can help the immune system of people who are overweight and showing early signs of metabolic issues like prediabetes, fatty liver, or mild high blood pressure.
ViennaAges 18–75 - NCT06092463Recruiting
Immune system study in newborn intestines
This study looks at how the immune system develops in the intestines of newborns, including those born early or with a blocked intestine (atresia). It may help doctors understand inflammation and improve care for sick babies.
CopenhagenAges Up to 1 year - NCT07075185RecruitingPhase 1
Gene therapy study for hard-to-treat multiple myeloma
This study tests a new gene therapy for people with multiple myeloma that has come back or stopped responding to at least 3 prior treatments. The therapy is designed to help your immune system fight the cancer cells more effectively.
Duarte, CaliforniaAges 18 years+ - NCT07042295RecruitingPhase 2
Amivantamab or Cetuximab for Skin Cancer in People with Weakened Immune Systems
This trial tests two drugs, amivantamab with hyaluronidase or cetuximab, in people with weakened immune systems who have advanced skin cancer (squamous cell carcinoma). The goal is to see if these treatments can help shrink or control the cancer.
Birmingham, AlabamaAges 18 years+ - NCT07024238Enrolling by invitation
Short-chain fatty acid supplement for kidney transplant patients
This study tests whether taking a short-chain fatty acid (a type of fiber-like substance) supplement can improve gut health in people who have had a kidney transplant. It may help keep the transplant working well.
Martin, SlovakiaAges 18 years+ - NCT07020156RecruitingPhase 1
First test of drug OX118 in healthy people
This early-phase trial tests a new drug called OX118 in healthy volunteers to see if it is safe and how the body processes it. It is a first step in developing a potential new treatment.
UppsalaAges 18–60 - NCT06996652RecruitingPhase 2
Study of adalimumab to delay Parkinson's symptoms in sleep disorder
This trial tests whether adalimumab, an immune system drug, helps people with REM sleep behavior disorder (a condition that may warn of Parkinson's disease) stay healthy longer. Participants will receive injections of the drug or a placebo to see if it prevents Parkinson's-related brain problems.
Los Angeles, CaliforniaAges 50–80 - NCT06626269Recruiting
Biomarkers for immunotherapy in digestive and gynecological cancers
This study looks for new markers in the blood or tumor that could predict how well immunotherapies work for advanced digestive and gynecological cancers. It includes people getting immunotherapy, chemotherapy, or targeted therapy, and also those with certain liver or abdominal metastases that can be surgically removed after chemo.
BesançonAges 18 years+ - NCT06826066Recruiting
How your immune system reacts to radiation therapy
This study looks at how your immune system affects how your body reacts to radiation therapy. It involves a blood sample and is for people who have had radiation but no major side effects.
Créteil, Île-de-France RegionAges 18 years+ - NCT06635863Enrolling by invitationPhase 4
Steroids versus standard heart medications for heart inflammation
This study compares two treatment strategies for people with unexplained heart failure and irregular heartbeats caused by inflammation: one group gets standard heart medications plus an immune-suppressing steroid (prednisone), and the other gets standard medications alone. Doctors want to see whether adding steroids helps improve heart function and control dangerous heart rhythms.
Phoenix, ArizonaAges 18 years+ - NCT06622174RecruitingPhase 1
Pulse radiation to help immunotherapy work better in lung cancer
This trial tests if a special type of radiation (pulse radiotherapy) can help your immune system fight cancer when it's not responding well to immunotherapy. It's for people with lung cancer that has spread to five or more areas and is growing despite treatment with PD(L)-1 inhibitors.
Montreal, QuebecAges 18 years+ - NCT06575426RecruitingPhase 1/Phase 2
Pig pancreatic cell transplant for type 1 diabetes
This trial tests a new treatment made from pig pancreatic cells (called OPF-310) that are placed under the skin to help control blood sugar in people with type 1 diabetes. It is for those whose diabetes is difficult to manage and who have dangerous low blood sugar episodes.
Chicago, IllinoisAges 35–70 - NCT06133530Enrolling by invitation
Human milk sugars for gut health in Antarctica
This study tests whether natural sugars found in human milk (called HMOs) can improve gut health and the immune system. Researchers are looking for healthy adults who are willing to travel to Antarctica for the study.
ErfurtAges 18–65
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Common questions
- Are there clinical trials for immune system?
- Yes. Clin2 currently lists 126 recruiting immune system studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a immune system trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a immune system trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.