Clinical trials
Immunology clinical trials
Below are recruiting immunology clinical trials, each written for real people, not researchers. We’re tracking 136 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06691035RecruitingPhase 1
Targeting ESR1 mutation in hormone-positive breast cancer
This trial tests a new treatment for metastatic breast cancer that is hormone receptor-positive and HER2-negative, and has a specific genetic change called an ESR1 mutation. The goal is to see if targeting this mutation can help control the cancer.
Tampa, FloridaAges 18 years+ - NCT06726785Recruiting
Gene changes in nasal cells of RLS patients on long-term dopamine agonist
This study looks at changes in a gene (DRD2) in nasal cells of people with Restless Legs Syndrome who are taking a dopamine agonist medication for a long time. It aims to understand how this gene might be involved in RLS.
San Francisco, CaliforniaAges 18–60 - NCT06733987Recruiting
Pembrolizumab and immune aging in relapsed Hodgkin lymphoma
This study looks at how a type of immune cell aging (called 'immunological senescence') might affect how well the drug pembrolizumab works in people whose Hodgkin lymphoma has come back or not responded to treatment.
BolognaAges 18 years+ - NCT06756152RecruitingPhase 2/Phase 3
Preventing GVHD after transplant for blood cancers in children and young adults
This trial tests a combination of four medicines (cyclophosphamide, abatacept, vedolizumab, and ruxolitinib) to prevent graft-versus-host disease (GVHD) after a stem cell transplant for children and young adults with certain blood cancers. The goal is to see if this approach reduces the risk of GVHD, a serious complication where donor cells attack the body.
MoscowAges 1 day–21 years - NCT06762002Recruiting
Immune system study for people with certain immune weaknesses
This study is for adults whose immune system has trouble fighting viruses due to specific antibodies or a genetic condition. Researchers want to follow these people over time to better understand the condition and improve care.
LilleAges 18 years+ - NCT06809075Recruiting
Stem cell therapy to help highly sensitized patients get a kidney transplant
This trial tests if a special stem cell treatment (using your own stem cells) can reset your immune system so you can accept a kidney from a deceased donor, even if you have very high antibody levels that make it hard to find a match. It's for people who have been waiting a long time and haven't had a transplant offer.
BarcelonaAges 18–65 - NCT06873100RecruitingPhase 1/Phase 2
Upadacitinib for relapsing polychondritis
This trial tests whether upadacitinib, an oral medication, is safe and effective for people with relapsing polychondritis that hasn't improved enough with standard treatments. It aims to reduce inflammation and control symptoms.
Beijing, Beijing MunicipalityAges 18–70 - NCT06882850Recruiting
Immune system study during pregnancy
This study looks at how the immune system works during pregnancy, focusing on women at high risk for preeclampsia. Researchers want to understand immune changes before any treatment is started.
Coimbra, Coimbra DistrictAges 18 years+ - NCT06892015Recruiting
Oropouche virus shedding and immune response study
This study monitors how long the Oropouche virus stays in the body and how the immune system responds after a positive diagnosis. It may help us better understand the course of the infection and improve patient care.
Negrar, VRAges 18 years+ - NCT06945861Recruiting
Immune aspects of TTP study
This trial is looking at the immune system's role in thrombotic thrombocytopenic purpura (TTP), a rare blood disorder. It may help researchers understand the condition better and possibly improve future treatments.
RouenAges 18 years+ - NCT07012928Recruiting
Study of immune responses in eosinophilic esophagitis patients
This study looks at how the immune system and the esophageal barrier function in people with eosinophilic esophagitis (EoE) compared to those without. It involves taking biopsies during an upper endoscopy to understand the disease better. The results may help improve treatments for EoE.
Amsterdam, North HollandAges 18–75 - NCT07012915Recruiting
Study of Immune Causes of Implant Inflammation
This trial studies severe inflammation around dental implants (peri-implantitis). It aims to understand the immune and tissue changes causing this condition, which may lead to new treatment approaches.
Wroclaw, Lower Silesian VoivodeshipAges 18 years+ - NCT07019857Recruiting
Thymus removal and immunity in infant heart surgery
This study looks at how removing the thymus gland during infant heart surgery affects the immune system. It compares babies who have their thymus removed with those who have heart surgery without removing it, and with babies having other types of surgery.
NantesAges Up to 6 months - NCT07050888Recruiting
Inulin supplement study for type 1 diabetes
This study tests if taking inulin, a type of fiber, can help improve blood sugar control and immune health in people with type 1 diabetes. Participants will take a daily supplement for a period of time to see if it makes a difference.
AmsterdamAges 18–70 - NCT07111598Recruiting
Iron supplements and the immune system in HHT
This study looks at how iron supplements affect the immune system in people with HHT (a genetic condition that causes bleeding from abnormal blood vessels). You may be placed in one of three groups depending on your iron and ferritin levels.
Bron, RhoneAges 18–99 - NCT07111793Recruiting
Study of severe bacterial infections in children
This study looks at children who had a severe bacterial infection in the past to understand why some get very sick. It may help find better ways to prevent or treat these infections in the future.
Nantes, Loire AtlantiqueAges Any age - NCT07124858Recruiting
Fruquintinib for advanced colorectal cancer
This study tracks how well fruquintinib works for people with advanced colorectal cancer that has spread. It aims to find factors that predict better outcomes, using blood and tumor samples.
Poitiers, FranceAges 18 years+ - NCT07153211Recruiting
Chemicals in spinal fluid and blood during spinal cord stimulation for nerve pain
This study is testing a spinal cord stimulation treatment for long-term nerve pain. It will look at certain chemicals in your spinal fluid and blood to understand how the treatment works.
BydgoszczAges 18–80 - NCT07232134RecruitingPhase 3
Treating AML in children with Down syndrome
This trial tests a treatment plan for children with Down syndrome who have been diagnosed with acute myeloid leukemia (AML) or a related bone marrow condition. The goal is to see how well the therapy works and to help guide doctors in choosing the best approach.
MoscowAges 1 day–18 years - NCT07681973Recruiting
Smell training for loss of smell in sinus patients
This study tests whether smell training can improve your sense of smell and affect your immune system. It is for people with chronic sinus inflammation and nasal polyps who have lost their sense of smell.
Cleveland, OhioAges 18 years+ - NCT07256210RecruitingPhase 2
Donor NK cells to prevent leukemia return after stem cell transplant
This trial tests whether giving donor natural killer (NK) cells after a stem cell transplant can help prevent leukemia from coming back. It is for people aged 14-25 with certain hard-to-treat leukemias who are already getting a stem cell transplant from a related donor.
MoscowAges 1 month–25 years - NCT07329595Recruiting
Tracking gut bacteria changes after severe burns
This study looks at how severe burns change the bacteria in your gut and your immune system. It will track these changes to better understand recovery and find new ways to help healing.
Debrecen, Hajdú-BiharAges 18–65 - NCT07345169Recruiting
Immune and inflammation study in ICU patients
This study looks at how your immune system and inflammation affect your recovery in the intensive care unit. Researchers want to understand why some patients do better than others.
ParisAges 18 years+ - NCT07366801RecruitingPhase 2/Phase 3
Preventing graft versus host disease in children with blood cancer
This trial tests if adding special immune cells (Treg cells) to a stem cell transplant from a half-matched donor can lower the risk of graft versus host disease (a serious side effect where donor cells attack the patient's body) in children and young adults with blood cancers.
MoscowAges 1–25
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Common questions
- Are there clinical trials for immunology?
- Yes. Clin2 currently lists 136 recruiting immunology studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a immunology trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a immunology trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.