Clinical trials
Injection clinical trials
Below are recruiting injection clinical trials, each written for real people, not researchers. We’re tracking 2,089 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03812874RecruitingPhase 1/Phase 2
Drug after chemo-embolization for liver cancer that can’t be removed
This Phase 1/2 study tests PTX-9908 (a study drug) to see if it’s safe and effective when given after TACE, a liver-directed treatment. It may help people with liver cancer that can’t be surgically removed and who have recovered enough from their recent TACE.
New Taipei City, TaiwanAges 20 years+ - NCT03910738RecruitingPhase 2
Testosterone treatment for nerve protection and myelin repair in MS
This Phase 2 study tests whether taking testosterone (for low testosterone levels) can help protect nerves and repair myelin in people with relapsing-remitting multiple sclerosis (MS). It may be most relevant if your MS is stable and you have low blood testosterone without current androgen treatment.
BesançonAges 18–55 - NCT03968913RecruitingEarly Phase 1
Biologic shot to prevent knee arthritis after ACL injury
This early-phase trial tests a biologic medicine (anakinra) given after an ACL injury to try to prevent or reduce later osteoarthritis (wear-and-tear arthritis). It enrolls young adults who recently tore their ACL and are planning a specific type of ACL reconstruction.
Los Angeles, CaliforniaAges 18–35 - NCT04020510RecruitingPhase 4
Standard versus fewer bladder Botox injections for overactive bladder
This study compares the usual amount of Botox injected into the bladder versus a smaller amount. It aims to see whether fewer injections can reduce overactive bladder symptoms with fewer side effects, like trouble emptying the bladder.
Bethesda, MarylandAges 18 years+ - NCT04375033RecruitingPhase 4
Oral versus injection buprenorphine for opioid use disorder
This trial compares taking buprenorphine by mouth versus as an injection for opioid use disorder. It aims to see which option helps people stay on treatment and reduces opioid use over about a year.
Tuscaloosa, AlabamaAges 18 years+ - NCT04383808Recruiting
PET/MRI scan with a small injected tracer
This study tests a new brain PET “insert” that can work at the same time as MRI to create brain images. If you’re healthy and can receive an approved injected tracer (FDG or Neuraceq), you may be able to help confirm the device works safely and clearly.
Palo Alto, CaliforniaAges 21 years+ - NCT04588077RecruitingPhase 4
Two-dose vs three-dose hepatitis B vaccine for cirrhosis
This study compares giving the hepatitis B vaccine in 2 doses versus 3 doses for people with cirrhosis who do not yet have protection against hepatitis B. It may help your care team choose the schedule most likely to build lasting immunity.
Baltimore, MarylandAges 18 years+ - NCT04663750RecruitingPhase 3
Surgery to treat bleeding under the retina in wet macular degeneration
This trial tests whether a specific eye surgery plus targeted clot-busting medicine and gas can improve vision after bleeding under the retina from “wet” age-related macular degeneration. It aims to reduce how long the bleeding lasts and help protect the central vision.
BonnAges 50–120 - NCT04754737Recruiting
Testing antibiotic timing before bladder Botox injections
This study looks at whether taking antibiotics shortly before bladder Botox injections affects outcomes for people with overactive bladder. It aims to clarify what to do about antibiotic use before treatment.
Stony Brook, New YorkAges 18 years+ - NCT04770207RecruitingPhase 2
Injecting a cancer drug mixture directly into tumors
This Phase 2 study tests a treatment where drug-loaded tiny beads are injected into a solid tumor, using more than one medicine. It may help people with advanced solid cancers by delivering the drugs right at the tumor site.
Guangzhou, GuangdongAges 18–99 - NCT04901273Recruiting
PRP shot vs placebo for knee osteoarthritis in adults 65+
This trial compares an injection made from your own platelets (PRP) to a placebo shot to see if it helps knee osteoarthritis symptoms and function. It is designed for people over 65 with arthritis affecting only one knee.
BolognaAges 65 years+ - NCT04912843RecruitingPhase 2/Phase 3
Gene therapy for inherited optic nerve vision loss
This trial tests a gene therapy injection into the eye to improve vision in people with a specific type of inherited optic nerve disease called Leber’s hereditary optic neuropathy (LHON). It is aimed at people who have a particular genetic change and a history of vision loss lasting long enough to measure change, while checking for safety first.
BeijingAges 12–75 - NCT07697937RecruitingPhase 2
YH02 injection for advanced solid tumors that didn't respond to treatment
This trial tests a new injection, YH02, directly into tumors for people with advanced solid tumors (like head and neck, breast, or melanoma) that are no longer responding to standard treatments. The goal is to see if it can shrink tumors or slow disease progression.
TianjinAges 18 years+ - NCT06809998RecruitingPhase 1/Phase 2
Steroid injection in non-surgical knee before knee replacement
This study tests whether a single steroid injection in the healthy knee (the one not being replaced) can reduce pain and improve recovery after total knee replacement. It may help people who have arthritis in both knees but are only having one replaced now.
Toronto, OntarioAges 18 years+ - NCT04937998Recruiting
PRP or hyaluronic acid injections for knee cartilage pain
This trial compares two injection treatments—platelet-rich plasma (PRP) and hyaluronic acid (HA)—for pain from osteoarthritis in the kneecap area. It looks to see which injection works better and for whom, using symptom follow-up and imaging.
BolognaAges 30–65 - NCT04992572RecruitingEarly Phase 1
Comparing two types of anesthesia for back decompression surgery
This early study compares two anesthesia approaches during lumbar decompression (back surgery to relieve pressure on nerves). It may help improve comfort and safety during surgery, but whether you personally benefit is not yet known.
Redwood City, CaliforniaAges 40–95 - NCT04995003RecruitingPhase 1
HER2 CAR T plus pembrolizumab for advanced HER2 sarcoma
This Phase 1 study tests a personalized immune-cell treatment (HER2 CAR T cells) given with an immune “checkpoint” medicine (pembrolizumab or another checkpoint blocker) to shrink advanced HER2-positive sarcoma. It may help patients whose cancer is progressing or coming back after prior treatment.
Houston, TexasAges 1–25 - NCT05023369RecruitingPhase 4
Hip replacement patients may get an added steroid injection
This trial tests whether a steroid injection placed around the hip after hip replacement can reduce pain and shorten hospital stay. It is meant for older adults who are having hip replacement due to a broken femoral neck bone.
LuganoAges 50–90 - NCT05028062RecruitingPhase 4
Naltrexone injections for people who want to cut alcohol drinking
This Phase 4 study tests whether naltrexone injections can help people with alcohol use disorder (AUD) reduce or stop heavy drinking. You may get two injections over 8 weeks, and you can join if you meet specific drinking pattern and eligibility rules.
Philadelphia, PennsylvaniaAges 18–65 - NCT05065372RecruitingPhase 1
Metformin test with automated insulin in teens with type 1
This Phase 1 study tests how adding metformin affects blood flow in the kidneys, insulin sensitivity, and overall heart/metabolic health in young people with type 1 diabetes. It may help researchers understand whether this combo is safe and beneficial alongside automated or pump/shot insulin care.
Aurora, ColoradoAges 12–25 - NCT05123755RecruitingPhase 2
Testing a new medicine in hospitalized pneumonia patients needing oxygen
This Phase 2 trial tests an investigational medicine (given in increasing doses) for hospitalized people with pneumonia who need supplemental oxygen. It aims to see if the medicine is safe and potentially helps the pneumonia process in the early hospital period.
Newport Beach, CaliforniaAges 18 years+ - NCT05145361RecruitingEarly Phase 1
Study drug B001 for neuromyelitis optic spectrum disorder attacks
This early-phase study tests B001 injection to see if it can help people with neuromyelitis optica spectrum disorder (NMOSD) who have had recent relapses. It may be aimed at reducing future attacks and improving disability over time.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05193227RecruitingPhase 2
Slow-release lidocaine patch for pain after pelvic surgery
This Phase 2 study tests a slow-release form of lidocaine to reduce pain after surgery that uses a pelvic incision. If you’re having a qualifying pelvic operation, the study may help see whether this medication improves postoperative pain control.
Vancouver, British ColumbiaAges 19 years+ - NCT05292339RecruitingPhase 4
Ketorolac shot for painful hand and arm tendon/joint problems
This trial studies whether a ketorolac injection can safely reduce pain and symptoms from certain shoulder, elbow, hand, or wrist tendon or joint conditions. It may help people who haven’t had surgery for the problem yet.
Atlanta, GeorgiaAges 18 years+
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Common questions
- Are there clinical trials for injection?
- Yes. Clin2 currently lists 2,089 recruiting injection studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a injection trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a injection trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.