Clinical trials
Intraoperative clinical trials
Below are recruiting intraoperative clinical trials, each written for real people, not researchers. We’re tracking 284 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06660095Enrolling by invitation
Measuring p50 during liver transplant surgery
This study is testing a new way to measure something called 'p50' during liver transplant surgery to see if it can help doctors better manage your care. It is for people who are having a planned liver transplant and are in relatively stable but serious health condition.
MalatyaAges 18–65 - NCT06617208Recruiting
Brain wave monitoring during brain tumor surgery
This study tests a new way to monitor brain activity during surgery to remove brain tumors. It may help doctors better protect important brain functions during the operation.
Rotterdam, South HollandAges 18 years+ - NCT06600165Recruiting
AI-guided microscope for basal cell skin cancer surgery
This trial tests a special microscope that uses artificial intelligence (AI) to help surgeons see exactly where skin cancer (basal cell carcinoma) ends during surgery. This could help remove all cancer cells in one go, making repeat surgeries less likely.
Munich, BavariaAges Any age - NCT06536517RecruitingPhase 2
Methadone during hysterectomy to reduce pain pills
This study tests whether a single dose of methadone given during minimally invasive hysterectomy (for non-cancer reasons) can reduce the need for opioid pain pills after surgery. It aims to see if this approach helps with pain control and lessens opioid use.
Baltimore, MarylandAges 18 years+ - NCT06507293Recruiting
Pain relief methods comparison for lung surgery
This trial tests two numbing injections to see which reduces pain medicine use during lung surgery. A special pain monitor guides the treatment. It may help you need fewer opioids during your procedure.
KocaeliAges 18–65 - NCT06446648RecruitingEarly Phase 1
Green dye to improve recovery after prostate cancer surgery
This trial tests whether using a green dye (ICG) during robot-assisted prostate removal helps preserve urinary and sexual function. It is for men with localized prostate cancer and good baseline erectile function.
Orange, CaliforniaAges 18 years+ - NCT06375798Recruiting
Breast conservation with radiation during surgery for early breast cancer
This trial is for women aged 55 or older with very early-stage breast cancer (stage 0 or 1) who want to save their breast. It tests giving a single dose of radiation during the lumpectomy instead of weeks of daily radiation afterward.
Shijiazhuang, HebeiAges 55 years+ - NCT06409013Recruiting
Dye-guided surgery for sarcoma removal
This study tests whether using a special dye during surgery helps doctors see and remove sarcoma tumors more completely. It may help improve the chances that no cancer is left behind.
Rochester, MinnesotaAges 18 years+ - NCT05898581Recruiting
Compare two pain block methods for hip replacement surgery
This trial studies whether one type of numbing injection (a PENG block) works better than another method (local anesthetic injected into the surgical area) to control pain during and after total hip replacement. It may help choose the best pain plan for people having a specific surgical approach.
London, OntarioAges 19 years+ - NCT06377371RecruitingPhase 4
Intraoperative tracing of meningioma with copper-64 DOTATATE
This trial tests a special imaging agent called [Cu64]DOTATATE that helps surgeons see meningioma tumors during surgery. It may make tumor removal more complete and safer.
New York, New YorkAges 18–99 - NCT06357546Recruiting
Avoiding a bladder tube during planned c-section
This study looks at whether it is safe to skip placing a urinary catheter (a tube in the bladder) during a planned cesarean section. The goal is to see if this can lower discomfort and the risk of infection without causing problems.
MontpellierAges 18 years+ - NCT06335719Recruiting
Electrical stimulation during nerve grafting for facial paralysis
This trial tests whether using gentle electrical stimulation during surgery can improve the results of nerve grafting for people with facial paralysis on one side. It's for patients who are already planning a two-stage surgery to restore their smile.
Cleveland, OhioAges 18–80 - NCT06335862Enrolling by invitation
Surgery to stop windpipe collapse in babies with esophageal atresia
This trial tests a surgery called posterior tracheopexy to prevent the windpipe from collapsing in babies with esophageal atresia and tracheomalacia. It may help your child breathe more easily.
RotterdamAges 8 months+ - NCT06296277Recruiting
Breathing machine use during surgery
This study looks at how a breathing machine is used during surgery. It is for adults who need help breathing while under general anesthesia for their operation.
Alessandria, ItalyAges 18 years+ - NCT06291389Recruiting
Airway pressure changes during tummy tuck surgery
This trial tests how changes in airway pressure during tummy tuck surgery affect breathing after the operation. It is for healthy adults having a tummy tuck with muscle tightening.
Tanta, EgyptAges 20–50 - NCT06275542Enrolling by invitation
Removing breathing tube without standard monitoring device
This study tests if it is safe to remove the breathing tube after surgery based on oxygen levels without using a special nerve monitor. It may help find a simpler method for deciding when to take the tube out.
YogyakartaAges 18–60 - NCT06263075Recruiting
Monitoring during craniosynostosis surgery: comparing newer vs. traditional monitors
This study compares two types of monitors that track your baby's heart and blood flow during surgery to fix craniosynostosis. The goal is to see if a newer monitor works as well as the traditional one.
Bologna, BOAges 3 months–8 months - NCT06235125RecruitingPhase 1
Using Cytalux during lung surgery in children and teens
This study tests whether a dye called Cytalux, injected before lung surgery, can help surgeons see and remove cancer spots in children and teens with certain cancers. It may help make sure all visible cancer is removed during the operation.
Chicago, IllinoisAges 6–17 - NCT06229483RecruitingPhase 3
Does tranexamic acid reduce bleeding during brain tumor surgery?
This study tests whether a medication called tranexamic acid (TXA) given during brain tumor surgery can reduce bleeding. If you are having a standard craniotomy for a tumor and don’t have certain health risks, you may be eligible.
Halifax, Nova ScotiaAges 18–80 - NCT06015711Recruiting
Does a pre-surgery painkiller reduce strong IV pain meds needed?
This trial tests if taking Maxigesic® (a combination of two pain relievers) before surgery can lower the amount of a strong IV pain medicine called remifentanil needed during anesthesia. It may help patients have a smoother recovery with fewer side effects.
Suwon, Gyeonggi-doAges 19–60 - NCT06205160Recruiting
Flexible brain electrodes for epilepsy surgery
This trial is testing new flexible brain electrodes during epilepsy surgery. These electrodes may help doctors map brain activity better than standard rigid ones. If you are having surgery for epilepsy caused by a brain lesion, you might be able to join.
UtrechtAges 18 years+ - NCT03713268Recruiting
Using a scan to guide eye surgery in real time
This trial tests whether a special eye scan (OCT) can help guide eye surgery during the operation. It may improve how surgeons see and target the exact eye structures they need to treat.
Durham, North CarolinaAges 4 weeks+ - NCT06133842Recruiting
Brain blood flow and confusion after surgery study
This trial looks at how well the brain controls its own blood flow during non-cardiac surgeries. It aims to see if problems with this regulation are linked to confusion after surgery (delirium).
Boston, MassachusettsAges 60 years+ - NCT04811313Recruiting
Tranexamic acid for children having hip bone surgery
This study tests whether tranexamic acid (a medicine that helps reduce bleeding) can safely help children during certain hip bone operations. It may help lower blood loss around the surgery.
AsyutAges 1–18
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Common questions
- Are there clinical trials for intraoperative?
- Yes. Clin2 currently lists 284 recruiting intraoperative studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a intraoperative trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a intraoperative trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.