Clinical trials
Intraoperative clinical trials
Below are recruiting intraoperative clinical trials, each written for real people, not researchers. We’re tracking 275 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06450834Enrolling by invitation
Ostene in planned open back spine surgery
This trial tests an experimental bone healing material, Ostene, during spine surgery. It may help reduce scar tissue and improve fusion. You are likely eligible if you are having planned open back surgery for nerve decompression and fusion.
Baltimore, MarylandAges 18–88 - NCT05163639RecruitingEarly Phase 1
Noninvasive brain and spinal training for spinal cord injury
This early study tests a noninvasive way of training the nervous system to see how it affects “associative plasticity,” or the brain/spinal cord’s ability to change with practice. It may help researchers learn strategies that could improve function for people with spinal cord injury.
New York, New YorkAges 18–80 - NCT05595954Recruiting
Personalized anesthesia plan to protect the brain during heart surgery
This trial studies whether tailoring anesthesia and monitoring the brain’s blood-flow control during heart surgery can improve neurological outcomes (brain-related function and recovery). It may help by guiding anesthesia in a more individualized way and checking how well the brain is protected during the operation.
BaselAges 65 years+ - NCT07440667Recruiting
Fluid amounts during planned C-section and recovery
This trial compares giving less fluid versus more fluid during planned C-section surgery to see which approach leads to better recovery afterward.
Niğde, MerkezAges 18–45 - NCT07687095Recruiting
Music during breast surgery and anesthesia use
This trial tests whether listening to music during breast surgery can reduce the amount of anesthesia medication needed. If you're having breast surgery and can use headphones, this study may help make your experience more comfortable.
Bursa, BursaAges 18–70 - NCT06952608RecruitingPhase 4
Ciprofol for blood pressure stability in older adults on heart medications
This study tests whether ciprofol, a newer sedative, can help prevent low blood pressure during surgery in older patients who are already taking medications for high blood pressure or heart failure (called RAS inhibitors). It may be a good option if you're 65 or older, on these medications for more than 3 months, and having abdominal surgery lasting over 2 hours.
Hangzhou, ZhejiangAges 65 years+ - NCT05268432Recruiting
Testing a surgical help system during camera-based operations
This trial tests new technology that helps surgeons during operations that use cameras, robots, or imaging. If you’re having a surgery with these tools and you can consent, you may be able to participate by supporting the in-the-room demonstration.
Dresden, SaxonyAges 18 years+ - NCT07713121Recruiting
Keeping blood pressure up during surgery to prevent confusion in older adults
This trial tests whether keeping blood pressure at 85 mmHg or higher during surgery can reduce confusion (delirium) after surgery. It is for older adults with high blood pressure who are having non-cardiac surgery.
HamburgAges 65 years+ - NCT07656857Recruiting
Flexible brain sensor study for epilepsy surgery
This trial tests a new flexible brain sensor to help guide surgery for people with drug-resistant focal epilepsy. It aims to find exactly where seizures start so surgeons can remove that area safely.
Beijing, Beijing MunicipalityAges 3–60 - NCT06044909Recruiting
Guiding liver surgery with combined images
This trial tests a new method that combines different medical images (CT, MRI, ultrasound) to help guide surgeons during laparoscopic (keyhole) liver surgery. It may make the surgery more precise and safer.
Saint-EtienneAges 18 years+ - NCT06091904Recruiting
Sufentanil for brain bypass surgery patients
This trial tests the pain medicine sufentanil to see how it affects blood pressure and heart rate during brain bypass surgery. It may help doctors better manage anesthesia for people having this type of surgery.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT04938765RecruitingPhase 4
Magnesium before surgery to improve nerve monitoring
This trial tests whether giving a one-time magnesium dose (through an IV) before or during surgery changes how well doctors can monitor nerves while you’re under anesthesia. It may help make nerve monitoring more reliable during spine or brain operations.
Loma Linda, CaliforniaAges 18–80 - NCT05106322Recruiting
Using a hand scanner to check fat buildup in liver grafts
This study tests whether an on-site, hand-held scanner during surgery can estimate fat-related liver changes in donated liver tissue. It may help surgeons better assess the quality of liver grafts while the transplant is happening.
VillejuifAges 18 years+ - NCT03868150RecruitingPhase 4
Preventing an abnormal heart rhythm after heart surgery
This trial studies whether giving a medication (amiodarone) during and after certain heart surgeries can help prevent atrial fibrillation, an irregular heartbeat that can happen after surgery. It may help by aiming to stop this rhythm problem before it starts.
Stanford, CaliforniaAges 18 years+ - NCT06204926Recruiting
AI predicts SMILE surgery results and risks
This trial tests if an AI program can predict complications and recovery after SMILE eye surgery for nearsightedness. It may help you understand your risks if you are a candidate for this surgery.
Nanchang, JiangxiAges 18–45 - NCT03441165Recruiting
Measure knee looseness during ACL and meniscus surgery
This trial checks how loose the knee feels during surgery for ACL reconstruction, ACL revision, or meniscus transplantation. The goal is to better assess knee stability during the operation, which may help surgeons choose the best repair.
Bologna, ItaliaAges 14–65 - NCT05828862Recruiting
Checks blood-pressure drops during major upper stomach surgery
This trial studies what happens when blood pressure drops during planned (elective) major upper gastrointestinal surgery and looks at related blood chemistry. Your care team may collect samples during the operation to understand why this happens and how to improve outcomes.
TaipeiAges 20–80 - NCT07339475Recruiting
Using vein size to predict blood pressure drops in older adults during hip or leg surgery
This study uses an ultrasound to measure the size of a vein in your leg before surgery to see if it can predict a drop in blood pressure during the procedure. If you are over 60 and having planned lower-limb surgery with spinal anesthesia, this non-invasive test might help your doctors prepare for your care.
CairoAges 60 years+ - NCT05653687Recruiting
Hip replacement surgery: X-ray guidance versus usual hand placement
This trial compares two ways of guiding hip replacement surgery during the operation. It may help improve how accurately the surgeon places the hip components and how well patients do afterward.
Lugano, Canton TicinoAges 18–90 - NCT06966518Recruiting
Ketamine and magnesium for pain control after nose surgery
This study tests whether giving a combination of two medicines (ketamine and magnesium sulfate) during nose surgery can help reduce pain after the operation. It may be a good option for healthy adults having rhinoplasty and looking for better pain control.
CairoAges 18–65 - NCT07396636Recruiting
Using machine learning to manage low blood pressure during surgery
This study tests whether an AI tool can help doctors better manage low blood pressure during planned surgeries. If you are having an elective surgery with general anesthesia and need an arterial line for monitoring, this trial may be for you.
Konya, Konya/MeramAges 18 years+ - NCT06897514Recruiting
Testing a device to predict low blood pressure during surgery
This trial is testing a non-invasive device that predicts low blood pressure during surgery. It aims to help doctors prevent dangerous drops in blood pressure, making surgery safer for patients.
SeoulAges 19 years+ - NCT07638579Enrolling by invitation
Nerve monitoring methods during thyroid and parathyroid surgery
This study compares two ways to monitor nerves during thyroid or parathyroid surgery to see which method works better. During surgery, doctors use electrical sensors to make sure they don't accidentally damage important nerves in your neck.
ThessalonikiAges Any age - NCT07301307Recruiting
Blood pressure and fluid management during surgery
This trial tests a new tool that helps doctors manage fluids and blood pressure during surgery. It uses a special index (HPI) and computer-assisted fluid management to keep your blood pressure stable, which may reduce complications.
Athens, AtticaAges 18 years+
Hear when a new Intraoperative trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for intraoperative?
- Yes. Clin2 currently lists 275 recruiting intraoperative studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a intraoperative trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a intraoperative trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.