Clinical trials
Intraoperative clinical trials
Below are recruiting intraoperative clinical trials, each written for real people, not researchers. We’re tracking 283 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06450834Enrolling by invitation
Ostene in planned open back spine surgery
This trial tests an experimental bone healing material, Ostene, during spine surgery. It may help reduce scar tissue and improve fusion. You are likely eligible if you are having planned open back surgery for nerve decompression and fusion.
Baltimore, MarylandAges 18–88 - NCT05163639RecruitingEarly Phase 1
Noninvasive brain and spinal training for spinal cord injury
This early study tests a noninvasive way of training the nervous system to see how it affects “associative plasticity,” or the brain/spinal cord’s ability to change with practice. It may help researchers learn strategies that could improve function for people with spinal cord injury.
New York, New YorkAges 18–80 - NCT05595954Recruiting
Personalized anesthesia plan to protect the brain during heart surgery
This trial studies whether tailoring anesthesia and monitoring the brain’s blood-flow control during heart surgery can improve neurological outcomes (brain-related function and recovery). It may help by guiding anesthesia in a more individualized way and checking how well the brain is protected during the operation.
BaselAges 65 years+ - NCT07831590Recruiting
Tracking awareness during laparoscopic surgery
This trial tests if a special brain monitor can help track awareness during laparoscopic surgery while under general anesthesia. Participation may help improve safety and comfort during surgery.
DüzceAges 18 years+ - NCT07440667Recruiting
Fluid amounts during planned C-section and recovery
This trial compares giving less fluid versus more fluid during planned C-section surgery to see which approach leads to better recovery afterward.
Niğde, MerkezAges 18–45 - NCT07396636Recruiting
Using machine learning to manage low blood pressure during surgery
This study tests whether an AI tool can help doctors better manage low blood pressure during planned surgeries. If you are having an elective surgery with general anesthesia and need an arterial line for monitoring, this trial may be for you.
Konya, Konya/MeramAges 18 years+ - NCT03107520RecruitingEarly Phase 1
Ultrasound during hip surgery to check blood flow
This early-phase study tests a special ultrasound with an added contrast medicine (Lumason) during surgery for babies with developmental dysplasia of the hip (DDH). It aims to better see blood flow at the time of surgery, which may help guide and improve care.
Philadelphia, PennsylvaniaAges 4 months–2 years - NCT07301307Recruiting
Blood pressure and fluid management during surgery
This trial tests a new tool that helps doctors manage fluids and blood pressure during surgery. It uses a special index (HPI) and computer-assisted fluid management to keep your blood pressure stable, which may reduce complications.
Athens, AtticaAges 18 years+ - NCT06703814Recruiting
Protective breathing support during robot surgery
This trial tests a special way of breathing support during robot-assisted surgery to protect your lungs. It's for people who are at higher risk of lung problems after surgery.
Innsbruck, TyrolAges 18 years+ - NCT07349784Recruiting
Automated lung opening steps during laparoscopic surgery
This trial tests a computer-controlled method to open collapsed lung parts during laparoscopic colorectal cancer surgery. It aims to improve breathing and reduce complications after surgery.
Istanbul, BakırkoyAges 18–80 - NCT07339475Recruiting
Using vein size to predict blood pressure drops in older adults during hip or leg surgery
This study uses an ultrasound to measure the size of a vein in your leg before surgery to see if it can predict a drop in blood pressure during the procedure. If you are over 60 and having planned lower-limb surgery with spinal anesthesia, this non-invasive test might help your doctors prepare for your care.
CairoAges 60 years+ - NCT04938765RecruitingPhase 4
Magnesium before surgery to improve nerve monitoring
This trial tests whether giving a one-time magnesium dose (through an IV) before or during surgery changes how well doctors can monitor nerves while you’re under anesthesia. It may help make nerve monitoring more reliable during spine or brain operations.
Loma Linda, CaliforniaAges 18–80 - NCT06204926Recruiting
AI predicts SMILE surgery results and risks
This trial tests if an AI program can predict complications and recovery after SMILE eye surgery for nearsightedness. It may help you understand your risks if you are a candidate for this surgery.
Nanchang, JiangxiAges 18–45 - NCT07315308Recruiting
Nerve block before heart surgery and painkiller use
This study tests whether a numbing injection in the chest before heart surgery can reduce the amount of pain medicine needed during the operation. It may help you manage pain better and recover more comfortably.
Gaziantep, SahinbeyAges 18–65 - NCT07250399Recruiting
Pain after root canal treatment with different tools
This trial compares two different ways of cleaning a tooth's root canal to see which causes less pain during and after treatment. It is for people with severe tooth pain in an upper premolar.
CairoAges 20–50 - NCT07141732RecruitingPhase 1
Brain radiation therapy during surgery for new glioblastoma
This trial tests giving a precise dose of radiation directly to the tumor area during surgery for newly diagnosed glioblastoma. The goal is to destroy remaining tumor cells immediately after removal, which may improve outcomes.
Moscow, MoscowAges 40–75 - NCT07108764Recruiting
Medicine to prevent confusion after abdominal surgery in seniors
This trial tests giving either lidocaine or dexmedetomidine during abdominal surgery to see if it helps keep the brain healthy and lowers the chance of waking up confused or agitated. It is for older adults having planned abdominal surgery who are otherwise in fairly good health.
Tanta, El-GharbiaAges 65 years+ - NCT07030231Enrolling by invitation
Intraoperative radiation therapy for breast cancer
This trial tests a type of radiation given during breast cancer surgery. It may be used alone or with standard radiation after surgery, and is also open to people whose breast cancer has come back.
Barcelona, BarcelonaAges 18 years+ - NCT06966518Recruiting
Ketamine and magnesium for pain control after nose surgery
This study tests whether giving a combination of two medicines (ketamine and magnesium sulfate) during nose surgery can help reduce pain after the operation. It may be a good option for healthy adults having rhinoplasty and looking for better pain control.
CairoAges 18–65 - NCT06952608RecruitingPhase 4
Ciprofol for blood pressure stability in older adults on heart medications
This study tests whether ciprofol, a newer sedative, can help prevent low blood pressure during surgery in older patients who are already taking medications for high blood pressure or heart failure (called RAS inhibitors). It may be a good option if you're 65 or older, on these medications for more than 3 months, and having abdominal surgery lasting over 2 hours.
Hangzhou, ZhejiangAges 65 years+ - NCT06911528Recruiting
New cell-probing technology for early breast cancer surgery
This trial tests a new technology that helps doctors examine cells during surgery for early-stage breast cancer. It may help make the sentinel lymph node biopsy more accurate.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06897514Recruiting
Testing a device to predict low blood pressure during surgery
This trial is testing a non-invasive device that predicts low blood pressure during surgery. It aims to help doctors prevent dangerous drops in blood pressure, making surgery safer for patients.
SeoulAges 19 years+ - NCT06876376Recruiting
Ultrasound during surgery for bowel endometriosis
This trial uses ultrasound during surgery to help surgeons find and remove endometriosis from the bowel and nearby areas. It may improve outcomes for people with deep endometriosis affecting the bowel.
BarcelonaAges 18 years+ - NCT06814353Enrolling by invitation
Studying where medulloblastoma starts in the brain
This trial observes where medulloblastoma tumors first appear and how they grow during surgery. It helps doctors better understand these rare childhood and adult brain tumors.
Vienna, State of ViennaAges Any age
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Common questions
- Are there clinical trials for intraoperative?
- Yes. Clin2 currently lists 283 recruiting intraoperative studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a intraoperative trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a intraoperative trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.