Clinical trials
Intraoperative clinical trials
Below are recruiting intraoperative clinical trials, each written for real people, not researchers. We’re tracking 284 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04938765RecruitingPhase 4
Magnesium before surgery to improve nerve monitoring
This trial tests whether giving a one-time magnesium dose (through an IV) before or during surgery changes how well doctors can monitor nerves while you’re under anesthesia. It may help make nerve monitoring more reliable during spine or brain operations.
Loma Linda, CaliforniaAges 18–80 - NCT03868150RecruitingPhase 4
Preventing an abnormal heart rhythm after heart surgery
This trial studies whether giving a medication (amiodarone) during and after certain heart surgeries can help prevent atrial fibrillation, an irregular heartbeat that can happen after surgery. It may help by aiming to stop this rhythm problem before it starts.
Stanford, CaliforniaAges 18 years+ - NCT03441165Recruiting
Measure knee looseness during ACL and meniscus surgery
This trial checks how loose the knee feels during surgery for ACL reconstruction, ACL revision, or meniscus transplantation. The goal is to better assess knee stability during the operation, which may help surgeons choose the best repair.
Bologna, ItaliaAges 14–65 - NCT03107520RecruitingEarly Phase 1
Ultrasound during hip surgery to check blood flow
This early-phase study tests a special ultrasound with an added contrast medicine (Lumason) during surgery for babies with developmental dysplasia of the hip (DDH). It aims to better see blood flow at the time of surgery, which may help guide and improve care.
Philadelphia, PennsylvaniaAges 4 months–2 years - NCT07877285Recruiting
Nutrition and monitoring to prevent confusion after gynecologic cancer surgery
This trial tests whether giving special nutrition before and possibly during surgery, along with careful brain monitoring during anesthesia, can reduce confusion (delirium) after surgery in older women with gynecologic cancer.
Elâzığ, ElâzığAges 65–80 - NCT05477680Recruiting
Measuring brain shift during brain tumor surgery
This study looks at how the brain may shift during surgery for certain brain tumors. The goal is to improve the accuracy of the navigation system so surgeons can remove tumors more precisely.
MoscowAges 18–80 - NCT07617428Enrolling by invitation
Testing a new blood loss monitor during surgery
This study tests a new system designed to accurately measure blood loss during elective surgery. If you're having planned urological or general surgery, this trial may help doctors better monitor your blood during the procedure.
Lanzhou, GansuAges 18 years+ - NCT06307548RecruitingPhase 1/Phase 2
Image-guided surgery and light therapy for colorectal cancer
This trial tests a special dye that helps surgeons see tumors more clearly during surgery, followed by a light therapy to destroy any remaining cancer cells. It is for people with advanced or returning colorectal cancer who are already scheduled for surgery.
Buffalo, New YorkAges 18 years+ - NCT04666103Recruiting
Study of neck anatomy in thyroid surgery
This study looks at how the structures in the neck affect thyroid surgery outcomes. You may be asked about your diagnosis and pre-surgery neck imaging to better understand surgical safety for people with certain thyroid conditions.
Wuhan, HubeiAges 18–75 - NCT06031181RecruitingPhase 3
Sublobar resection for early lung cancer found during surgery
This trial tests if a smaller surgery (sublobar resection) works well for patients with very early-stage lung cancer (adenocarcinoma in situ or minimally invasive adenocarcinoma) that is found during the operation. It may help avoid removing more lung tissue than necessary.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07856017Recruiting
Smarter prostate biopsy using imaging and metabolic data
This study tests a new biopsy system that uses MRI images and metabolic information to guide doctors to the most suspicious areas of the prostate during the biopsy. This could make the biopsy more accurate and help diagnose prostate cancer better.
ShanghaiAges 55 years+ - NCT07871188Recruiting
Blood pressure swings and recovery after heart bypass surgery
This study looks at how changes in blood pressure during heart bypass surgery relate to how quickly the body clears lactic acid afterwards, which is a sign of recovery. It may help doctors understand recovery patterns after surgery.
GaziantepAges 18–80 - NCT07868614Recruiting
Comparing brain signal recordings during deep brain stimulation surgery
This study compares a new device for recording brain signals during deep brain stimulation (DBS) surgery with the standard equipment. DBS is a treatment for movement disorders like Parkinson's disease that uses a device to send electrical signals to specific parts of the brain.
Rochester, MinnesotaAges 18 years+ - NCT07869407Recruiting
Painless cavity filling: new tools vs traditional drill
This trial compares two newer methods for removing tooth decay (smart burs and a dissolving gel called Carisolv) to the traditional drill, to see which causes less pain during the procedure. It may help find a more comfortable way to treat cavities.
Peshawar, Khyber PakhtunkhwaAges 18–45 - NCT02884271Recruiting
Study CPR during surgery when the heart stops
This trial looks at cardiopulmonary resuscitation (CPR) provided right in the operating room when a patient’s heart stops. It may help improve how emergency care is delivered during surgery.
IzmirAges Any age - NCT07867106Recruiting
Discomfort during cesarean delivery under spinal anesthesia
This study asks patients about any discomfort they felt during their cesarean section while under spinal or epidural anesthesia. The goal is to understand and improve the birthing experience.
Toronto, OntarioAges 18 years+ - NCT06273176Recruiting
Surgery with or without brain mapping for recurrent glioblastoma
This study is testing whether using a special brain-mapping technique during surgery helps people with recurrent glioblastoma. It compares standard surgery to surgery with mapping to see if it leads to better outcomes for tumors near important brain areas.
San Francisco, CaliforniaAges Up to 90 years - NCT07854704Recruiting
Controlled body temperature during long abdominal surgery
This study tests a method to keep the body temperature stable during long abdominal surgery. It may help reduce complications and improve recovery.
Saint PetersburgAges 18 years+ - NCT07857655RecruitingPhase 4
Intraoperative methadone for pain after head and neck cancer surgery
This trial tests whether giving methadone during your head and neck cancer surgery helps control pain right after the operation. Methadone is a long-acting painkiller that might reduce pain for up to a day or more, potentially improving your recovery experience.
Portland, OregonAges 18–89 - NCT04603209Recruiting
Check-in registry for radiation during breast-conserving surgery
This registry study tracks people with early-stage, single-area breast cancer to understand outcomes when radiation is given during breast-conserving surgery. It may help doctors improve treatment planning for patients like you.
Santa Monica, CaliforniaAges 18 years+ - NCT06398028RecruitingPhase 4
ICG dye before minimally invasive liver surgery
This study tests whether giving a special dye (ICG) before minimally invasive liver surgery helps surgeons see tumors more clearly compared to using ultrasound alone. It’s for people who are already scheduled for keyhole liver surgery.
BarcelonaAges 18 years+ - NCT06358807Recruiting
Microfracture with PRP gel for ankle cartilage injury
This trial tests a surgery called microfracture (making tiny holes in the bone to help new cartilage grow) combined with a gel made from your own platelet-rich plasma (PRP) to treat a small ankle cartilage injury. The goal is to see if adding PRP gel improves healing and reduces pain.
BeijingAges 18–60 - NCT07826858Recruiting
Special camera to guide prostate cancer surgery
This study tests a special camera that helps surgeons see prostate cancer tissue more clearly during surgery. It may help make surgery more precise, which could improve outcomes.
Geneva, Canton of GenevaAges 18 years+ - NCT07825337Recruiting
Futuristic headset to help surgeons see during eye surgery
This study tests whether a futuristic headset that projects digital information can help surgeons see better during eye surgery. You may be able to participate if you are having a standard eye procedure and have no other eye problems that could make surgery riskier.
Brentwood, New YorkAges 18–90
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Common questions
- Are there clinical trials for intraoperative?
- Yes. Clin2 currently lists 284 recruiting intraoperative studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a intraoperative trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a intraoperative trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.