Clinical trials
Intraoperative clinical trials
Below are recruiting intraoperative clinical trials, each written for real people, not researchers. We’re tracking 283 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07141732RecruitingPhase 1
Brain radiation therapy during surgery for new glioblastoma
This trial tests giving a precise dose of radiation directly to the tumor area during surgery for newly diagnosed glioblastoma. The goal is to destroy remaining tumor cells immediately after removal, which may improve outcomes.
Moscow, MoscowAges 40–75 - NCT07108764Recruiting
Medicine to prevent confusion after abdominal surgery in seniors
This trial tests giving either lidocaine or dexmedetomidine during abdominal surgery to see if it helps keep the brain healthy and lowers the chance of waking up confused or agitated. It is for older adults having planned abdominal surgery who are otherwise in fairly good health.
Tanta, El-GharbiaAges 65 years+ - NCT06966518Recruiting
Ketamine and magnesium for pain control after nose surgery
This study tests whether giving a combination of two medicines (ketamine and magnesium sulfate) during nose surgery can help reduce pain after the operation. It may be a good option for healthy adults having rhinoplasty and looking for better pain control.
CairoAges 18–65 - NCT06219252Recruiting
Comparing lens power methods during cataract surgery
This study compares two ways to choose the right lens power during cataract surgery: one uses a special measurement during surgery, the other uses standard pre-surgery measurements. The goal is to see which method gives you better vision after surgery.
Mexico City, CuauhtemocAges 40 years+ - NCT06897514Recruiting
Testing a device to predict low blood pressure during surgery
This trial is testing a non-invasive device that predicts low blood pressure during surgery. It aims to help doctors prevent dangerous drops in blood pressure, making surgery safer for patients.
SeoulAges 19 years+ - NCT06687356Recruiting
Using OCT during lens surgery for better results
This study uses a special imaging technique called optical coherence tomography (OCT) during lens surgery to help doctors see inside your eye more clearly. It may be a good option if you need surgery for a cataract or a lens that is out of place.
Hangzhou, ZhejiangAges 18 years+ - NCT07030231Enrolling by invitation
Intraoperative radiation therapy for breast cancer
This trial tests a type of radiation given during breast cancer surgery. It may be used alone or with standard radiation after surgery, and is also open to people whose breast cancer has come back.
Barcelona, BarcelonaAges 18 years+ - NCT04847284Recruiting
Radiation during brain tumor surgery for brain metastases
This trial tests giving targeted radiation while surgeons are operating to treat brain metastases. It may help control the cancer locally at the time of surgery, especially for certain single lesions.
BarcelonaAges 18 years+ - NCT06952608RecruitingPhase 4
Ciprofol for blood pressure stability in older adults on heart medications
This study tests whether ciprofol, a newer sedative, can help prevent low blood pressure during surgery in older patients who are already taking medications for high blood pressure or heart failure (called RAS inhibitors). It may be a good option if you're 65 or older, on these medications for more than 3 months, and having abdominal surgery lasting over 2 hours.
Hangzhou, ZhejiangAges 65 years+ - NCT06876376Recruiting
Ultrasound during surgery for bowel endometriosis
This trial uses ultrasound during surgery to help surgeons find and remove endometriosis from the bowel and nearby areas. It may improve outcomes for people with deep endometriosis affecting the bowel.
BarcelonaAges 18 years+ - NCT06814353Enrolling by invitation
Studying where medulloblastoma starts in the brain
This trial observes where medulloblastoma tumors first appear and how they grow during surgery. It helps doctors better understand these rare childhood and adult brain tumors.
Vienna, State of ViennaAges Any age - NCT03629418Recruiting
Blood-pressure strategy to prevent kidney injury after heart bypass
This trial tests a targeted way to manage blood pressure before and after off-pump heart bypass surgery, with the goal of reducing acute kidney injury (sudden kidney problems). It may help some people by lowering stress on the kidneys during and right after surgery.
Beijing, Beijing MunicipalityAges 50 years+ - NCT06703814Recruiting
Protective breathing support during robot surgery
This trial tests a special way of breathing support during robot-assisted surgery to protect your lungs. It's for people who are at higher risk of lung problems after surgery.
Innsbruck, TyrolAges 18 years+ - NCT06574022RecruitingPhase 4
Comparing two pain blocks for mastectomy recovery
This trial compares two types of pain blocks (PECS-II and pectoral blocks) to see which works better after mastectomy. The goal is to improve pain control and recovery for patients with breast cancer or high risk.
Cincinnati, OhioAges 18 years+ - NCT04949646Recruiting
Nerve monitoring during rectal cancer surgery
This trial studies whether checking pelvic nerve signals during rectal cancer surgery (total mesorectal excision) is helpful. It may help surgeons avoid nerve injury while removing the cancer.
LarissaAges 18–90 - NCT06511037RecruitingEarly Phase 1
Dye injection to help see cancer during belly surgery
This study tests a special dye, called pafolacianine, that is injected before surgery to help surgeons see hidden cancer spots in the belly during the operation. The goal is to see if using this dye improves how completely the cancer is removed in people with gastrointestinal cancer that has spread to the belly lining.
Orange, CaliforniaAges 18 years+ - NCT06091904Recruiting
Sufentanil for brain bypass surgery patients
This trial tests the pain medicine sufentanil to see how it affects blood pressure and heart rate during brain bypass surgery. It may help doctors better manage anesthesia for people having this type of surgery.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT06351475Recruiting
Albumin during surgery for advanced cancer in the abdomen
This trial tests whether adding a protein called albumin to standard fluids given during surgery helps patients with advanced cancer in the abdomen (from the ovaries, uterus, or digestive system) recover better. You would receive either the usual fluids or fluids plus albumin during your operation.
LyonAges 18–80 - NCT06256354Recruiting
Managing body temperature during cancer surgery to prevent confusion
This trial tests whether carefully managing a patient's body temperature during cancer surgery can reduce the risk of postoperative delirium and improve long-term survival. It is for older adults undergoing major cancer surgery.
Chizhou, AnhuiAges 65 years+ - NCT06204926Recruiting
AI predicts SMILE surgery results and risks
This trial tests if an AI program can predict complications and recovery after SMILE eye surgery for nearsightedness. It may help you understand your risks if you are a candidate for this surgery.
Nanchang, JiangxiAges 18–45 - NCT05653687Recruiting
Hip replacement surgery: X-ray guidance versus usual hand placement
This trial compares two ways of guiding hip replacement surgery during the operation. It may help improve how accurately the surgeon places the hip components and how well patients do afterward.
Lugano, Canton TicinoAges 18–90 - NCT05671458Recruiting
Imaging guidance during head and neck tumor surgery plus radiation
This trial tests whether advanced imaging used during surgery can better guide where surgeons remove head-and-neck tumors. It also studies how this approach works alongside planned postoperative radiation therapy, which may be needed for more advanced tumors.
HeidelbergAges 18 years+ - NCT05268432Recruiting
Testing a surgical help system during camera-based operations
This trial tests new technology that helps surgeons during operations that use cameras, robots, or imaging. If you’re having a surgery with these tools and you can consent, you may be able to participate by supporting the in-the-room demonstration.
Dresden, SaxonyAges 18 years+ - NCT04938765RecruitingPhase 4
Magnesium before surgery to improve nerve monitoring
This trial tests whether giving a one-time magnesium dose (through an IV) before or during surgery changes how well doctors can monitor nerves while you’re under anesthesia. It may help make nerve monitoring more reliable during spine or brain operations.
Loma Linda, CaliforniaAges 18–80
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Common questions
- Are there clinical trials for intraoperative?
- Yes. Clin2 currently lists 283 recruiting intraoperative studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a intraoperative trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a intraoperative trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.