Clinical trials
Intraoperative clinical trials
Below are recruiting intraoperative clinical trials, each written for real people, not researchers. We’re tracking 272 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03975179Recruiting
Frozen biopsy vs no frozen biopsy during breast-conserving surgery
This study compares two approaches during breast-conserving surgery: doing a quick “frozen section” biopsy during the operation versus deciding later without it. It aims to see which approach better guides treatment decisions about whether the cancer is close to the removed tissue edges (margins).
Goyang-siAges 19–70 - NCT04847284Recruiting
Radiation during brain tumor surgery for brain metastases
This trial tests giving targeted radiation while surgeons are operating to treat brain metastases. It may help control the cancer locally at the time of surgery, especially for certain single lesions.
BarcelonaAges 18 years+ - NCT04949646Recruiting
Nerve monitoring during rectal cancer surgery
This trial studies whether checking pelvic nerve signals during rectal cancer surgery (total mesorectal excision) is helpful. It may help surgeons avoid nerve injury while removing the cancer.
LarissaAges 18–90 - NCT05168839RecruitingPhase 3
Using dye scans during surgery to help prevent leakage
This trial tests whether using a special dye and camera during colorectal cancer surgery can help lower the risk of a surgical “leak” where the bowel is joined. If you’re having a planned left-sided colectomy or high rectal resection, the scan may help surgeons see blood flow more clearly.
AmiensAges 18 years+ - NCT05268432Recruiting
Testing a surgical help system during camera-based operations
This trial tests new technology that helps surgeons during operations that use cameras, robots, or imaging. If you’re having a surgery with these tools and you can consent, you may be able to participate by supporting the in-the-room demonstration.
Dresden, SaxonyAges 18 years+ - NCT05648474Recruiting
Nerve monitoring during a low-back fusion surgery
This study tests whether special nerve monitoring during a low-back fusion helps make surgery safer and the results easier to judge. It’s for people having a specific type of low-back fusion on one or two levels.
Carlsbad, CaliforniaAges 18 years+ - NCT05671458Recruiting
Imaging guidance during head and neck tumor surgery plus radiation
This trial tests whether advanced imaging used during surgery can better guide where surgeons remove head-and-neck tumors. It also studies how this approach works alongside planned postoperative radiation therapy, which may be needed for more advanced tumors.
HeidelbergAges 18 years+ - NCT06182111Recruiting
Morphine during gallbladder removal
This study gives morphine during gallbladder removal surgery to see how it affects pain afterward. It may help you have less pain and recover more comfortably.
EsbjergAges 21 years+ - NCT06219252Recruiting
Comparing lens power methods during cataract surgery
This study compares two ways to choose the right lens power during cataract surgery: one uses a special measurement during surgery, the other uses standard pre-surgery measurements. The goal is to see which method gives you better vision after surgery.
Mexico City, CuauhtemocAges 40 years+ - NCT06256354Recruiting
Managing body temperature during cancer surgery to prevent confusion
This trial tests whether carefully managing a patient's body temperature during cancer surgery can reduce the risk of postoperative delirium and improve long-term survival. It is for older adults undergoing major cancer surgery.
Chizhou, AnhuiAges 65 years+ - NCT06291714Recruiting
Non-invasive blood pressure prediction during major surgery
This trial tests a new, non-invasive way to predict drops in blood pressure during major hip, knee, pelvis, or spine surgery. The goal is to help doctors prevent low blood pressure, which can lead to complications.
GiessenAges 45 years+ - NCT06351475Recruiting
Albumin during surgery for advanced cancer in the abdomen
This trial tests whether adding a protein called albumin to standard fluids given during surgery helps patients with advanced cancer in the abdomen (from the ovaries, uterus, or digestive system) recover better. You would receive either the usual fluids or fluids plus albumin during your operation.
MontpellierAges 18–80 - NCT06511037RecruitingEarly Phase 1
Dye injection to help see cancer during belly surgery
This study tests a special dye, called pafolacianine, that is injected before surgery to help surgeons see hidden cancer spots in the belly during the operation. The goal is to see if using this dye improves how completely the cancer is removed in people with gastrointestinal cancer that has spread to the belly lining.
Orange, CaliforniaAges 18 years+ - NCT06545786Recruiting
Brain monitoring during surgery to prevent confusion
This study uses a special brain-wave monitor during your surgery to see if it can predict confusion or memory problems afterward. It may help you and your doctors better understand your recovery.
Moscow, Moscow OblastAges 18 years+ - NCT06574022RecruitingPhase 4
Comparing two pain blocks for mastectomy recovery
This trial compares two types of pain blocks (PECS-II and pectoral blocks) to see which works better after mastectomy. The goal is to improve pain control and recovery for patients with breast cancer or high risk.
Cincinnati, OhioAges 18 years+ - NCT06687356Recruiting
Using OCT during lens surgery for better results
This study uses a special imaging technique called optical coherence tomography (OCT) during lens surgery to help doctors see inside your eye more clearly. It may be a good option if you need surgery for a cataract or a lens that is out of place.
Hangzhou, ZhejiangAges 18 years+ - NCT06778811RecruitingPhase 4
Sleep quality study for heart surgery patients
This trial studies sleep problems before and after heart surgery. It tests two medicines to see if they can help improve sleep. This may help you recover better after surgery.
Nanjing, JiangsuAges 40–75 - NCT06876376Recruiting
Ultrasound during surgery for bowel endometriosis
This trial uses ultrasound during surgery to help surgeons find and remove endometriosis from the bowel and nearby areas. It may improve outcomes for people with deep endometriosis affecting the bowel.
BarcelonaAges 18 years+ - NCT06911528Recruiting
New cell-probing technology for early breast cancer surgery
This trial tests a new technology that helps doctors examine cells during surgery for early-stage breast cancer. It may help make the sentinel lymph node biopsy more accurate.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06952608RecruitingPhase 4
Ciprofol for blood pressure stability in older adults on heart medications
This study tests whether ciprofol, a newer sedative, can help prevent low blood pressure during surgery in older patients who are already taking medications for high blood pressure or heart failure (called RAS inhibitors). It may be a good option if you're 65 or older, on these medications for more than 3 months, and having abdominal surgery lasting over 2 hours.
Hangzhou, ZhejiangAges 65 years+ - NCT07108764Recruiting
Medicine to prevent confusion after abdominal surgery in seniors
This trial tests giving either lidocaine or dexmedetomidine during abdominal surgery to see if it helps keep the brain healthy and lowers the chance of waking up confused or agitated. It is for older adults having planned abdominal surgery who are otherwise in fairly good health.
Tanta, El-GharbiaAges 65 years+ - NCT07141732RecruitingPhase 1
Brain radiation therapy during surgery for new glioblastoma
This trial tests giving a precise dose of radiation directly to the tumor area during surgery for newly diagnosed glioblastoma. The goal is to destroy remaining tumor cells immediately after removal, which may improve outcomes.
Moscow, MoscowAges 40–75 - NCT07250399Recruiting
Pain after root canal treatment with different tools
This trial compares two different ways of cleaning a tooth's root canal to see which causes less pain during and after treatment. It is for people with severe tooth pain in an upper premolar.
CairoAges 20–50 - NCT07315308Recruiting
Nerve block before heart surgery and painkiller use
This study tests whether a numbing injection in the chest before heart surgery can reduce the amount of pain medicine needed during the operation. It may help you manage pain better and recover more comfortably.
Gaziantep, SahinbeyAges 18–65
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Common questions
- Are there clinical trials for intraoperative?
- Yes. Clin2 currently lists 272 recruiting intraoperative studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a intraoperative trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a intraoperative trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.