Clinical trials
Intraoperative clinical trials
Below are recruiting intraoperative clinical trials, each written for real people, not researchers. We’re tracking 284 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07285187Recruiting
Vein congestion and confusion after heart surgery trial
This trial looks at how blood backing up in veins after heart surgery might relate to delirium (sudden confusion). It uses a special ultrasound to check vein blood flow and then watches for confusion afterward.
Yangzhou, JiangsuAges 18 years+ - NCT07276789RecruitingPhase 2
Single-dose dye imaging for lung cancer surgery
This trial tests a single dose of a special dye (LS301-IT) that helps surgeons see lung cancer cells more clearly during surgery. It aims to make lung cancer removal more precise and complete.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06889532Recruiting
Wound care after sarcoma surgery: vacuum or standard dressing?
This study compares two wound care methods after surgery to remove a large sarcoma (a type of cancer) from the leg or groin. It tests whether a special vacuum dressing helps the wound heal better than standard care.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT05445960Recruiting
Tourniquet use during ankle surgery and recovery outcomes
This study looks at whether using a tourniquet during ankle fracture surgery affects healing, leg movement, and patient-reported recovery. It may help doctors choose the safest, most comfortable approach for surgery.
Portland, OregonAges 18–89 - NCT07264790RecruitingPhase 1
Minoxidil for Better Blood Flow in Breast Reconstruction
This trial tests whether applying minoxidil (a hair growth medication) to breast tissue during surgery can improve blood flow to the reconstructed breast. It is for women who are having both breasts removed to prevent cancer and have reconstruction on the same day.
Durham, North CarolinaAges 18 years+ - NCT06104059Recruiting
Pain management during planned laparoscopic surgery
This trial tests a new way to monitor pain during laparoscopic surgery. It may help your doctor adjust pain medicines to keep you comfortable.
Athens, AtticaAges 18–70 - NCT07239557Enrolling by invitation
Best timing for lung expansion moves during surgery
This trial tests different time intervals for a lung-opening technique (alveolar recruitment) during planned abdominal surgery, aiming to restore 90% of lung volume. It may help lower the risk of lung complications after surgery.
Guangzhou, GuangdongAges 65–80 - NCT07232277Recruiting
Vein congestion and kidney injury after heart surgery
This trial looks at how fluid buildup in veins might relate to kidney injury after planned heart surgery. It aims to find ways to prevent kidney damage. Participants must be having planned (non-emergency) heart surgery, be 18 or older, and have healthy kidneys and overall health.
Yangzhou, JiangsuAges 18 years+ - NCT07233954Recruiting
Can Fluorescein Dye Help Remove Brain Tumors?
This study tests whether using a fluorescent dye called fluorescein (injected into a vein during surgery) helps neurosurgeons better see and remove aggressive brain or spinal cord tumors. It may lead to safer, more complete tumor removal.
MilanAges Any age - NCT07229040RecruitingPhase 2
Kidney protection during heated chemotherapy surgery for ovarian cancer
This trial tests two drugs (cilastatin and thiosulfate) to see which one better protects the kidneys during surgery that uses heated cisplatin chemotherapy directly in the abdomen. It is for women with advanced ovarian cancer whose disease is mostly in the belly.
Madrid, MadridAges 18–75 - NCT07224243Recruiting
How oxygen during surgery affects recovery
This study looks at how different oxygen levels during surgery affect recovery. It includes adults having surgery with a breathing tube, but excludes people having open-heart surgery, certain lung procedures, or who have had bleomycin chemotherapy.
Ann Arbor, MichiganAges 18 years+ - NCT06918626Recruiting
Comparing two bile duct stone removal approaches during gallbladder surgery
This trial compares two ways of checking for and removing stones from the main bile duct during gallbladder surgery. One method uses a special scope (SpyGlass) during the operation, and the other does an MRI first. The goal is to see which approach is better for people with gallstone-related inflammation of the gallbladder who might have stones in the bile duct.
Pavia, PaviaAges 18 years+ - NCT06768580Recruiting
Melatonin or lidocaine to prevent confusion after hip replacement
This trial tests if giving either oral melatonin or lidocaine during surgery can reduce the chance of confusion (delirium) in older adults after total hip replacement. It compares these two approaches to standard care.
Tanta, El-GharbiaAges 65 years+ - NCT07211529Recruiting
Nerve block during chest surgery to reduce complications
This trial tests whether a numbing injection near the spine (paravertebral block) given during keyhole chest surgery can lower the risk of problems after surgery. It might help patients recover more comfortably.
Wuhan, HubeiAges 18–80 - NCT07194707Recruiting
How operating room noise affects brain activity during anesthesia
This trial studies whether the noise level in the operating room changes brain activity and vital signs while you are under general anesthesia. It may help doctors create a quieter, more comfortable environment during surgery.
Başakşehir, IstanbulAges 18–70 - NCT07197632Recruiting
MRI during brain metastasis surgery
This study uses an MRI scan during surgery to help doctors remove brain metastases more completely. It may help ensure that all tumor tissue is removed.
MunichAges 18 years+ - NCT07179991Recruiting
DDAVP (desmopressin) for bleeding during heart surgery
This study tests whether a medicine called desmopressin (DDAVP) can reduce bleeding during heart surgery. It uses a special blood test (TEG6) to decide who gets the medicine.
London, OntarioAges 18 years+ - NCT06895200Recruiting
Smart reminders for safer gallbladder surgery
This trial tests a smart reminder system to help surgeons follow safety steps during laparoscopic gallbladder removal. It aims to reduce risks and improve outcomes for patients with non-cancerous gallbladder disease.
StrasbourgAges 18 years+ - NCT06951802RecruitingPhase 4
Low-dose ketamine for pain during endometriosis surgery
This study tests whether giving a low dose of ketamine during endometriosis surgery can help reduce pain. If you qualify, you'll receive ketamine or a placebo during your procedure, and the team will check your pain levels afterward.
BernAges 18 years+ - NCT07166991RecruitingPhase 3
Anesthesia study for organ donation after brain death
This trial compares different anesthesia strategies used during organ donation surgery after brain death to see which one helps preserve organs better for transplant. It is for brain-dead adult patients in the ICU whose families agree to organ donation and research participation.
GrenobleAges 18 years+ - NCT07158372Recruiting
Using AI to identify key anatomy in gallbladder surgery videos
This trial uses artificial intelligence to analyze surgery videos and help surgeons identify important structures during gallbladder removal. It may lead to safer procedures.
Zhengzhou, HenanAges 18 years+ - NCT06956365Recruiting
Comparing two medicines for bleeding during c-section under general anesthesia
This trial compares two drugs, oxytocin and carbetocin, to see which one better controls blood pressure and heart rate changes during cesarean section surgery. Both medicines help the uterus contract after delivery to reduce bleeding.
Van, TuşbaAges 18–40 - NCT07149207RecruitingPhase 2
Using a dye during head and neck cancer surgery
This study tests whether a special dye (ICG) injected before surgery can help surgeons see head and neck cancer more clearly during the operation. It is for people with squamous cell carcinoma who are at risk of their cancer returning and are scheduled for surgery.
Charleston, South CarolinaAges 18 years+ - NCT06140927RecruitingPhase 3
Ketamine's effect on spinal monitoring during back surgery
This study tests if giving ketamine during certain back surgeries affects how well doctors can monitor your spinal nerves during the operation. It's for adults having a posterior spinal fusion.
San Francisco, CaliforniaAges 18–100
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Common questions
- Are there clinical trials for intraoperative?
- Yes. Clin2 currently lists 284 recruiting intraoperative studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a intraoperative trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a intraoperative trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.