Clinical trials
Intraoperative clinical trials
Below are recruiting intraoperative clinical trials, each written for real people, not researchers. We’re tracking 272 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06335719Recruiting
Electrical stimulation during nerve grafting for facial paralysis
This trial tests whether using gentle electrical stimulation during surgery can improve the results of nerve grafting for people with facial paralysis on one side. It's for patients who are already planning a two-stage surgery to restore their smile.
Cleveland, OhioAges 18–80 - NCT06358222Recruiting
Lung cancer trial testing blood test and PET scan for spread
This trial studies if a blood test that looks for tumor DNA combined with a PET-CT scan can better predict if lung cancer has spread to lymph nodes. It may help guide treatment decisions for people with non-small cell lung cancer that hasn't been treated yet.
ShanghaiAges 18–75 - NCT06358807Recruiting
Microfracture with PRP gel for ankle cartilage injury
This trial tests a surgery called microfracture (making tiny holes in the bone to help new cartilage grow) combined with a gel made from your own platelet-rich plasma (PRP) to treat a small ankle cartilage injury. The goal is to see if adding PRP gel improves healing and reduces pain.
BeijingAges 18–60 - NCT06375798Recruiting
Breast conservation with radiation during surgery for early breast cancer
This trial is for women aged 55 or older with very early-stage breast cancer (stage 0 or 1) who want to save their breast. It tests giving a single dose of radiation during the lumpectomy instead of weeks of daily radiation afterward.
Shijiazhuang, HebeiAges 55 years+ - NCT06377371RecruitingPhase 4
Intraoperative tracing of meningioma with copper-64 DOTATATE
This trial tests a special imaging agent called [Cu64]DOTATATE that helps surgeons see meningioma tumors during surgery. It may make tumor removal more complete and safer.
New York, New YorkAges 18–99 - NCT06398028RecruitingPhase 4
ICG dye before minimally invasive liver surgery
This study tests whether giving a special dye (ICG) before minimally invasive liver surgery helps surgeons see tumors more clearly compared to using ultrasound alone. It’s for people who are already scheduled for keyhole liver surgery.
BarcelonaAges 18 years+ - NCT06493968Recruiting
Medications to reduce blood loss during C-section hysterectomy for PAS
This trial tests if giving a special medication during surgery can help reduce blood loss in women with a condition called PAS (where the placenta grows too deeply into the uterus) who are having a C-section and their uterus removed. It may make the surgery safer.
CairoAges 20–40 - NCT06507293Recruiting
Pain relief methods comparison for lung surgery
This trial tests two numbing injections to see which reduces pain medicine use during lung surgery. A special pain monitor guides the treatment. It may help you need fewer opioids during your procedure.
KocaeliAges 18–65 - NCT06510140Recruiting
Brain monitoring and frailty to predict confusion after surgery in older adults
This study tests if monitoring your brain waves during surgery and checking your frailty level can help predict whether you might become confused after surgery. It aims to improve care for older adults having major non-cardiac operations.
Saint-EtienneAges 75 years+ - NCT06521710Recruiting
Nerve grafting to preserve erections after prostate removal
This trial tests if a nerve grafting technique can help preserve erectile function after robotic surgery for high-risk localized prostate cancer. It may be an option for men with good preoperative erectile function.
Montreal, QuebecAges 18 years+ - NCT06536517RecruitingPhase 2
Methadone during hysterectomy to reduce pain pills
This study tests whether a single dose of methadone given during minimally invasive hysterectomy (for non-cancer reasons) can reduce the need for opioid pain pills after surgery. It aims to see if this approach helps with pain control and lessens opioid use.
Baltimore, MarylandAges 18 years+ - NCT06541041Recruiting
Nerve transfer with electrical stimulation for hand function after spinal injury
This trial tests a surgery that moves nerves (nerve transfers) plus gentle electrical stimulation to help people with spinal cord injury regain hand movement. It may be a good fit if you have a C6 or C7 injury and haven't had hand surgery before.
Palo Alto, CaliforniaAges 18–65 - NCT06594289Recruiting
Liver surgery trial with special blood flow control
This trial tests a new way to control blood flow during laparoscopic liver surgery. It compares two methods to see which is safer and more effective for patients with certain liver conditions.
Guangzhou, China/GuangdongAges 18–70 - NCT06600165Recruiting
AI-guided microscope for basal cell skin cancer surgery
This trial tests a special microscope that uses artificial intelligence (AI) to help surgeons see exactly where skin cancer (basal cell carcinoma) ends during surgery. This could help remove all cancer cells in one go, making repeat surgeries less likely.
Munich, BavariaAges Any age - NCT06619002Recruiting
Using video to make uterine cancer surgery safer
This study is collecting videos from a type of minimally invasive surgery called sentinel lymph node dissection for endometrial or cervical cancer. The goal is to use deep learning (a type of artificial intelligence) to help surgeons identify important structures and any spread of cancer during the procedure, making the surgery safer and more effective.
RomaAges 18–99 - NCT06621823Recruiting
Robotic ultrasound to check lymph nodes during gynecologic cancer surgery
This trial tests a new robotic ultrasound tool to see if it can better find cancer in lymph nodes during surgery. It may help doctors decide exactly which nodes to remove, avoiding unnecessary surgery.
RomaAges 18–99 - NCT06656949Recruiting
ICG injection for lymph node mapping in endometrial cancer
This trial tests whether injecting a dye called indocyanine green (ICG) in different spots can better find sentinel lymph nodes during surgery for endometrial cancer. It may help doctors remove fewer nodes and reduce side effects.
Jinan, ShandongAges 18–80 - NCT06701422Recruiting
Neck Spinal Cord Stimulation for Recovery After Surgery
This study tests if electrical stimulation of the spinal cord in the neck can help you recover function after cervical spine surgery. It is for people who need neck surgery and do not already have a stimulator device in their neck or chest.
New York, New YorkAges 18 years+ - NCT07149207RecruitingPhase 2
Using a dye during head and neck cancer surgery
This study tests whether a special dye (ICG) injected before surgery can help surgeons see head and neck cancer more clearly during the operation. It is for people with squamous cell carcinoma who are at risk of their cancer returning and are scheduled for surgery.
Charleston, South CarolinaAges 18 years+ - NCT07683247Recruiting
Energy use during ACL reconstruction surgery
This study measures how much energy your body uses during ACL reconstruction surgery. It uses a special vest to track your heart rate and breathing, which may help surgeons understand how your body handles the operation.
LecceAges 16–49 - NCT06962007Recruiting
Jaw clenching after sugammadex for muscle relaxation reversal
This trial tests whether a drug called sugammadex, which reverses muscle relaxation from anesthesia, might cause jaw clenching in some people. The study will watch for this effect during routine surgery to better understand the risk.
Iksan, Jeonbuk-doAges 19–70 - NCT07681245Recruiting
Laser imaging plus AI for faster lung surgery diagnosis
This study tests a new laser imaging tool that works with artificial intelligence to give fast, accurate results during lung surgery. If you are already scheduled to have lung surgery for a suspicious spot, the laser scan will be done on your tissue and compared to the standard frozen section and final lab results.
Shanghai, Shanghai MunicipalityAges 18–90 - NCT06710405RecruitingPhase 4
Lidocaine for pain relief after children's chest surgery
This trial tests whether giving lidocaine during surgery can reduce pain and speed up recovery in children under 7 having chest surgery with a camera. If it works, it could mean less pain and a faster return to normal after the operation.
SeoulAges 6 months–7 years - NCT06711432Recruiting
Blood Pressure Management During Tumor Surgery and Brain Function
This trial compares different blood pressure management strategies during abdominal tumor surgery to see which one better protects cognitive function (thinking, memory, and clarity). It is for patients who have multiple stroke risk factors and are undergoing a lengthy surgery.
Hangzhou, ZhejiangAges 40–85
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Common questions
- Are there clinical trials for intraoperative?
- Yes. Clin2 currently lists 272 recruiting intraoperative studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a intraoperative trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a intraoperative trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.