Clinical trials
Ischemia Limb clinical trials
Below are recruiting ischemia limb clinical trials, each written for real people, not researchers. We’re tracking 62 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05055297Recruiting
Drug-coated balloon for severe leg artery blockage in lower legs
This trial studies a “drug-coated balloon” procedure to improve blood flow in people with severe, long-lasting poor circulation in the lower leg arteries. It may help reduce repeat blockage after treatment for selected artery lesions below the knee.
Chandler, ArizonaAges 18 years+ - NCT05620095Recruiting
Drug-coated balloon angioplasty for lower leg artery blockages
This trial tests whether a drug-coated balloon can better reopen blocked arteries in the lower leg (below the knee). It may help keep blood flow open and reduce the chance the blockage comes back, after a procedure to cross and open the narrowed area.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06071429Recruiting
Dissolvable medicine stent for leg artery disease
This trial tests a new dissolvable stent that slowly releases medicine to keep your lower-leg artery open. It is for people with severe leg pain or small wounds due to poor blood flow, and who are not eligible for other stents.
New York, New YorkAges 18 years+ - NCT06082466Recruiting
Comparing two types of leg bypass surgery
This study compares two types of bypass surgery for blocked leg arteries. One uses a standard vein from your own body, and the other uses a vein supported by a special metal frame. The goal is to see which works better and lasts longer.
SalzburgAges 18 years+ - NCT06263322Recruiting
Recovery tracking after leg artery surgery
This study tests a mobile app to track your recovery after surgery for severe leg artery disease. The goal is to see if using the app helps improve your recovery and quality of life.
Gainesville, FloridaAges 60–100 - NCT06264843Recruiting
Peripheral bypass quality check study
This trial is testing a new way to check the quality of leg bypass surgery while you're still in the operating room, using a special device. It may help ensure the bypass is working well right away, which could reduce the risk of future problems.
San Francisco, CaliforniaAges 18 years+ - NCT06330493Recruiting
Study of a drug-coated balloon for leg artery disease
This trial tests a special balloon coated with medication to open up blocked arteries below the knee in people with serious leg circulation problems. It aims to improve blood flow and avoid amputation.
Concord, CaliforniaAges 18 years+ - NCT06713850Recruiting
Balloon treatment for leg artery blockages with calcium
This trial uses a special balloon (Shockwave IVL) to break up calcium in leg artery blockages, improving blood flow and reducing pain. It's for people with moderate to severe calcium buildup in the femoropopliteal artery.
Wuhan, HubeiAges 18 years+ - NCT06879561Recruiting
Wire-guided treatment for leg artery disease
This trial tests if using a special pressure-sensing wire during treatment of blocked leg arteries below the knee can improve outcomes for people with severe circulation problems that threaten the limb. It aims to help patients with Rutherford category 5 chronic limb threatening ischemia.
SeoulAges 19 years+ - NCT07330635Recruiting
Chronic wounds and blood circulation checkup
This study checks how well blood flows in the legs of people with and without chronic wounds or circulation problems. It may help doctors better understand and treat poor circulation.
TaipeiAges 20–95 - NCT07465627Recruiting
Vessel recoil study for below-knee artery disease
This study tests a new device called the Spur to open blocked arteries below the knee in people with severe leg pain or minor wounds. It is specifically for people who also have diabetes or are on dialysis.
GrazAges 18 years+ - NCT07472049Recruiting
Imaging plaque activity in peripheral artery disease
This trial studies plaque activity in leg arteries using a new imaging method to understand artery disease better. It may help people with peripheral artery disease get more targeted treatment.
Edinburgh, MidlothianAges 18 years+ - NCT07512960RecruitingPhase 3
Blood Thinner Duration After Leg Artery Treatment
This trial tests how long patients should take two blood-thinning medications (aspirin and clopidogrel) after treatment to restore blood flow to a severely damaged leg. The goal is to find the right balance between preventing clots and avoiding dangerous bleeding.
Paris, Île-de-France RegionAges 18–99 - NCT06421961Enrolling by invitation
AI smartphone app for monitoring leg ulcers in PAD
This study tests a smartphone-based tool that uses artificial intelligence to help monitor hard-to-heal leg ulcers caused by poor arterial blood flow. The goal is to see if the tool can accurately assess wound healing at home.
GothenburgAges 18 years+
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Common questions
- Are there clinical trials for ischemia limb?
- Yes. Clin2 currently lists 62 recruiting ischemia limb studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ischemia limb trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ischemia limb trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.