Clinical trials
Ischemia Limb clinical trials
Below are recruiting ischemia limb clinical trials, each written for real people, not researchers. We’re tracking 55 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06569771Recruiting
How patients feel about using their arm after stroke rehab
This study looks at how people feel about using their arm after a stroke during intensive rehab. It helps understand if therapy makes a difference in how you use your arm in daily life.
Charleroi, HainautAges 18 years+ - NCT06318767Recruiting
Foot Blood Flow Measurements to Predict Limb and Heart Events
This study measures how blood flows through your foot using ultrasound to see if it can predict serious problems with your leg or heart in people with severe circulation problems. The goal is to find a simple test that helps doctors decide the best treatment for you.
AmiensAges 18 years+ - NCT04027244Recruiting
Studying care plans for severe leg blood flow problems
This study looks at how best to manage severe leg ischaemia, a condition where blood flow to the leg is dangerously reduced. It mainly involves patients who are planning an intervention, and some participants may also do special heart imaging tests.
Leicester, LeicestershireAges 18–110 - NCT05698628Recruiting
Timing strategies to protect legs during peripheral ECMO
This trial studies whether an “early” or more “conservative” approach to improving blood flow to the leg can prevent limb damage during a type of heart-lung machine called peripheral VA-ECMO. It may help reduce the risk of poor leg blood flow (ischemia) in people with severe heart failure-related shock.
SeoulAges 19 years+ - NCT07588295Recruiting
How immune cells respond in heart and leg blood vessel disease
This study examines how immune cells (macrophages) behave differently in patients with blocked arteries in the heart or legs. Understanding this may help doctors develop better treatments for these conditions.
Cotignola, RavennaAges 18 years+ - NCT07397390Enrolling by invitation
Study of a new scoring balloon for leg artery blockages with heavy calcium buildup
This study tests a new balloon device that scores the artery walls to treat leg artery blockages with heavy calcium deposits. It aims to see if the device helps prepare the vessel safely and effectively before placing a stent.
Dalian, LiaoningAges 18–85 - NCT03594344Recruiting
Extra hyperbaric oxygen after leg amputation wounds heal
This study tests whether giving extra treatments with hyperbaric (pressure) oxygen after a leg amputation can improve healing or recovery. It’s meant for people whose amputation happened due to long-lasting infection or poor blood flow and who can attend follow-up visits.
OsloAges 18–90 - NCT07163234Recruiting
Safety of a groin artery tube for heart surgery
This study is testing a special tube (cannula) placed in the groin artery during heart surgery to connect a heart-lung machine. It's for people who are scheduled for planned heart surgery and may be helped by this refined device.
MassyAges 18 years+ - NCT07147790Enrolling by invitation
Silver spray and wound vacuum for diabetic foot wounds
This trial compares a special wound vacuum that adds silver nanoparticle spray to a standard wound vacuum. It's for people with diabetic foot wounds after a procedure to restore blood flow to their leg.
Kafr ash Shaykh, Kafrelshaykh GovernorateAges 40–80 - NCT06434194Recruiting
Stent study for severe leg pain or wounds
This trial tests a new stent to improve blood flow in blocked leg arteries causing severe pain or tissue loss. It may help if you have a long blockage in the upper leg but not below the knee.
New York, New YorkAges 19 years+ - NCT07052435Recruiting
Measuring pressure and flow during leg artery treatment
This study looks at how well blood flows through leg arteries after using a balloon to open blockages. It uses special measurements to check if the treatment fully restores blood flow, which may help guide future treatments.
PátraiAges Any age - NCT07006467Recruiting
Study of a dissolving scaffold for leg artery blockages
This trial tests a new type of absorbable scaffold (like a temporary mesh) that is placed inside a blocked artery below the knee to restore blood flow. It is for people with severe leg pain or small ulcers due to chronic limb-threatening ischemia (CLI) who have a short blockage in a specific artery.
GrazAges 18 years+ - NCT04433572RecruitingPhase 3
Temsirolimus treatment to improve below-knee artery procedures
This trial studies whether delivering a medicine called temsirolimus directly into the artery during a below-knee revascularization procedure can improve blood flow and outcomes. It may help people with severe leg artery disease who have symptoms like pain while walking or threatened limb tissue loss.
Houma, LouisianaAges 18 years+ - NCT05868161Recruiting
Registry for patients treated with a thrombectomy device
This registry collects past treatment information from people who had a clot procedure using the Pounce Thrombectomy System. It helps researchers understand how this device is used in real-world care and what outcomes may look like.
Peoria, IllinoisAges 18 years+ - NCT05145478Recruiting
Real-world outcomes after Shockwave treatment for blocked leg artery
This study follows what happens in real life after using Shockwave’s device (intravascular lithotripsy) to treat a hard, calcified blockage in the common femoral artery, then completing standard treatment. It may help doctors understand which patients benefit and what results to expect.
New Haven, ConnecticutAges 18 years+ - NCT04054609Recruiting
FAZA PET/MRI scan before and after leg revascularization
This study uses a special combined scan (PET/MRI) to look at blood flow and tissue changes in people with severely reduced blood supply to the legs. The scan is done before and after a procedure to reopen blocked blood vessels, to understand how well treatment works.
Toronto, OntarioAges 18 years+ - NCT07672249Recruiting
Study on iliac stenting to prevent major leg events
This study looks at people with narrowed or blocked arteries in the pelvis (iliac arteries) who receive a stent to improve blood flow. It aims to understand which factors might predict future serious problems in the legs, like worsening pain or amputation.
Milan, MiAges 18 years+ - NCT06082466Recruiting
Comparing two types of leg bypass surgery
This study compares two types of bypass surgery for blocked leg arteries. One uses a standard vein from your own body, and the other uses a vein supported by a special metal frame. The goal is to see which works better and lasts longer.
SalzburgAges 18 years+ - NCT06713850Recruiting
Balloon treatment for leg artery blockages with calcium
This trial uses a special balloon (Shockwave IVL) to break up calcium in leg artery blockages, improving blood flow and reducing pain. It's for people with moderate to severe calcium buildup in the femoropopliteal artery.
Wuhan, HubeiAges 18 years+ - NCT07512960RecruitingPhase 3
Blood Thinner Duration After Leg Artery Treatment
This trial tests how long patients should take two blood-thinning medications (aspirin and clopidogrel) after treatment to restore blood flow to a severely damaged leg. The goal is to find the right balance between preventing clots and avoiding dangerous bleeding.
Paris, Île-de-France RegionAges 18–99 - NCT07472049Recruiting
Imaging plaque activity in peripheral artery disease
This trial studies plaque activity in leg arteries using a new imaging method to understand artery disease better. It may help people with peripheral artery disease get more targeted treatment.
Edinburgh, MidlothianAges 18 years+ - NCT07465627Recruiting
Vessel recoil study for below-knee artery disease
This study tests a new device called the Spur to open blocked arteries below the knee in people with severe leg pain or minor wounds. It is specifically for people who also have diabetes or are on dialysis.
GrazAges 18 years+ - NCT07330635Recruiting
Chronic wounds and blood circulation checkup
This study checks how well blood flows in the legs of people with and without chronic wounds or circulation problems. It may help doctors better understand and treat poor circulation.
TaipeiAges 20–95 - NCT03622359Recruiting
Imaging blood flow in leg artery disease using a scan
This study uses a special “radiotracer” scan to look at how well blood flows through the arteries in the legs. It may help researchers better understand circulation problems from peripheral artery disease.
Columbus, OhioAges 18 years+
Hear when a new Ischemia Limb trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for ischemia limb?
- Yes. Clin2 currently lists 55 recruiting ischemia limb studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ischemia limb trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ischemia limb trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.