Clinical trials
Kidney Failure, Chronic clinical trials
Below are recruiting kidney failure, chronic clinical trials, each written for real people, not researchers. We’re tracking 220 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06725810RecruitingPhase 4
Enarodustat for anemia in chronic kidney disease (not on dialysis)
This trial tests enarodustat, a pill for anemia, in people with chronic kidney disease who are not on dialysis. It aims to see if it can safely raise hemoglobin levels.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06738394Recruiting
Exercise study for older adults with kidney disease
This study tests whether a supervised exercise program can help older adults with chronic kidney disease improve their physical function and stay active. You have to be able to do exercise and not be on dialysis.
Winston-Salem, North CarolinaAges 65–100 - NCT06578078RecruitingPhase 3
Best heart failure care for older patients with kidney disease
This study tests the best way to manage heart failure in older adults who also have kidney problems and high potassium levels. It compares different treatment strategies to see which one is safest and most effective.
Alcorcón, MadridAges 70 years+ - NCT06329622RecruitingPhase 3
Does Ketosteril help muscle loss in kidney disease?
This study tests whether a medicine called Ketosteril can improve muscle strength and function in people with moderate to severe chronic kidney disease (CKD) who also have sarcopenia (age-related muscle loss).
ShanghaiAges Any age - NCT06202235Recruiting
Magnetic resonance imaging for chronic kidney disease
This trial uses a special MRI technique called multifrequency magnetic resonance elastography (MRE) to see if it can help evaluate chronic kidney disease. It may provide a non-invasive way to monitor kidney health without needing a biopsy.
Shenyang, LiaoningAges 18–65 - NCT05732727RecruitingPhase 3
Stronger BP lowering using diuretics in kidney disease
This Phase 3 trial compares a plan that uses diuretics (water pills) to lower blood pressure more, versus usual blood pressure care, in people with uncontrolled hypertension and moderate-to-severe chronic kidney disease. It may help your blood pressure control while monitoring safety closely because kidney function changes how medicines work.
AngersAges 18 years+ - NCT04098354Recruiting
Phone monitoring for high blood pressure in kidney disease
This study tests whether using a home blood pressure monitoring device and phone-based check-ins can help people with high blood pressure and chronic kidney disease manage their health better. You may be asked to record readings and send them regularly during the study.
Edmonton, AlbertAges 18 years+ - NCT02411773RecruitingPhase 1
Test a nerve-blocking medicine in kidney disease
This Phase 1 study tests whether a medicine that reduces nerve signals (“sympatholysis”) is safe and how it affects people with chronic kidney disease. It may help researchers understand new ways to protect the kidneys, but the main goal here is safety.
Decatur, GeorgiaAges 18–75 - NCT02808572Recruiting
Blood and urine tests to study heart risk in kidney disease
This study looks for new markers in blood or urine that may help explain heart (cardiovascular) risk in people with chronic kidney disease. It may help doctors better predict risk, especially in those not yet on dialysis.
MontpellierAges 18–95 - NCT07851454Recruiting
Walnuts for heart and kidney health in chronic kidney disease
This trial tests whether eating walnuts every day can help protect the heart and kidneys in people with chronic kidney disease. It may help improve blood pressure, cholesterol, and blood sugar control.
Reus, TarragonaAges 45–75 - NCT07657286Recruiting
Exercise and inflammation in diabetic kidney disease
This trial tests whether exercise can help people with diabetes and chronic kidney disease by reducing inflammation and stress in the body. It may show if a workout program can improve overall health.
CairoAges 36–58 - NCT06551311Recruiting
Cycling exercise for chronic kidney disease
This study tests whether a special type of cycling exercise (eccentric cycling) is safe and helpful for people with moderate to severe chronic kidney disease (CKD) or who are on dialysis. The goal is to improve fitness and overall health.
Tainan, TaiwanAges 55–85 - NCT07153432Recruiting
Chronic kidney disease screening for at-risk adults
This study is a simple screening to check for early signs of chronic kidney disease. It aims to find kidney problems in people who are at higher risk due to age or other health conditions.
PragueAges 18 years+ - NCT07053462RecruitingPhase 1/Phase 2
Gene-edited kidney transplant to lower rejection risk
This trial tests a specially edited donor kidney designed to reduce the chance of rejection, especially for people with high sensitivity to donor kidneys. If it works, it could make more kidneys available for those who have a hard time finding a match.
Beijing, ChangpingAges 16–85 - NCT06841692Recruiting
Diuretic testing for moderate kidney disease
This study checks how well diuretics (water pills) work in people with moderate chronic kidney disease. It may help doctors understand how to better treat fluid buildup in patients.
Rotterdam, South HollandAges 18 years+ - NCT06721143RecruitingPhase 1/Phase 2
Study of AION-301 for chronic kidney disease
This trial tests an experimental drug called AION-301 for people with chronic kidney disease (CKD). The goal is to see if it's safe and may help slow kidney decline. It's given by IV infusion and compared to a placebo (inactive infusion).
Miami, FloridaAges 35–75 - NCT06056102RecruitingPhase 1
CAR-T cell therapy to help highly sensitized kidney transplant patients
This trial tests whether a special immune cell treatment (CAR-T cells) can lower the antibodies that make it very hard for you to receive a kidney transplant. If it works, you might become eligible for a transplant sooner.
Boston, MassachusettsAges 18–65 - NCT05370014Recruiting
Partner support program for chronic health conditions
This study tests a program that helps patients with chronic health conditions and their care partners work together to improve their health and well-being. If you live in a rural or underserved area in South Carolina and have a condition like diabetes or high blood pressure, you and your support person might be able to join.
Columbia, South CarolinaAges 18 years+ - NCT07180368Recruiting
Managing multiple medications in older adults
This study looks at how to better manage multiple medications in older adults with long-term health conditions. It aims to improve safety and reduce drug-related problems.
Xi'an, ShaanxiAges 65 years+ - NCT06987604Enrolling by invitation
Dialysis intensity for high ammonia in liver failure
This trial tests if a higher intensity of continuous dialysis (CRRT) better lowers ammonia levels in patients with liver failure. It aims to find the best approach to reduce brain complications from high ammonia.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06635525Recruiting
How kidney failure affects your flu shot response
This study looks at how well the flu vaccine works in people with kidney failure who are on dialysis compared to healthy people. It will help doctors understand how kidney problems affect the body’s immune response to vaccination.
MilanAges 18–70 - NCT07130955Enrolling by invitation
Ablation for hard-to-control high blood pressure with kidney disease
This study tests a new device that uses energy to calm kidney nerves, which may help lower blood pressure in people with chronic kidney disease whose blood pressure stays high despite taking multiple medications.
Beijing, Beijing MunicipalityAges 18–65 - NCT06741072RecruitingPhase 1
Vaccine to prevent EBV-related cancer in transplant patients
This trial tests a vaccine (OSU-2131) that may help prevent cancers caused by the Epstein-Barr virus in people waiting for an organ transplant. The vaccine is designed to train your immune system to fight the virus.
Columbus, OhioAges 18–65 - NCT06089057Enrolling by invitation
Social exercise program for aging with kidney disease
This study tests a program to help people with chronic kidney disease who are starting to feel frail (weak or slow). It uses social activities and gentle exercise to improve well-being and strength.
Nashville, TennesseeAges Any age
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Common questions
- Are there clinical trials for kidney failure, chronic?
- Yes. Clin2 currently lists 220 recruiting kidney failure, chronic studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a kidney failure, chronic trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a kidney failure, chronic trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.